ZA200704535B - Process for preparing rosuvastatin - Google Patents

Process for preparing rosuvastatin

Info

Publication number
ZA200704535B
ZA200704535B ZA200704535A ZA200704535A ZA200704535B ZA 200704535 B ZA200704535 B ZA 200704535B ZA 200704535 A ZA200704535 A ZA 200704535A ZA 200704535 A ZA200704535 A ZA 200704535A ZA 200704535 B ZA200704535 B ZA 200704535B
Authority
ZA
South Africa
Prior art keywords
preparing rosuvastatin
rosuvastatin
preparing
Prior art date
Application number
ZA200704535A
Other languages
English (en)
Inventor
Butters Michael
Murray Paul Michael
Lenger Steven Robert
Snape Evan William
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34130901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200704535(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of ZA200704535B publication Critical patent/ZA200704535B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200704535A 2004-12-24 2007-05-31 Process for preparing rosuvastatin ZA200704535B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0428328.9A GB0428328D0 (en) 2004-12-24 2004-12-24 Chemical process

Publications (1)

Publication Number Publication Date
ZA200704535B true ZA200704535B (en) 2008-11-26

Family

ID=34130901

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200704535A ZA200704535B (en) 2004-12-24 2007-05-31 Process for preparing rosuvastatin

Country Status (15)

Country Link
US (1) US8034932B2 (enExample)
EP (2) EP2361906A1 (enExample)
JP (1) JP5127460B2 (enExample)
KR (1) KR20070092307A (enExample)
CN (1) CN101084197B (enExample)
AU (1) AU2005317880B2 (enExample)
BR (1) BRPI0518647A2 (enExample)
CA (1) CA2589775A1 (enExample)
GB (1) GB0428328D0 (enExample)
IL (1) IL183528A (enExample)
MX (1) MX2007007777A (enExample)
NO (1) NO20072872L (enExample)
NZ (1) NZ555769A (enExample)
WO (1) WO2006067456A2 (enExample)
ZA (1) ZA200704535B (enExample)

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US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
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WO2008036286A1 (en) * 2006-09-18 2008-03-27 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin calcium
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US8183397B2 (en) 2007-04-03 2012-05-22 Lek Pharmaceuticals D.D. Synthesis of statins
EP1978020A1 (en) * 2007-04-03 2008-10-08 LEK Pharmaceuticals D.D. Processes for the preparation of statins, particularly rosuvastatin, and intermediates for the preparation thereof
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CN105669561B (zh) * 2014-11-19 2018-11-27 南京博优康远生物医药科技有限公司 一种4-(4-氟苯基)-5-烷氧基羰基-6-异丙基-3,4-二氢嘧啶-2(1h)-酮的制备方法
HUE069744T2 (hu) * 2015-01-23 2025-04-28 Centrient Pharmaceuticals Netherlands B V Fejlesztett eljárás a sztatin prekurzor elõállítására
KR20160126700A (ko) 2015-04-24 2016-11-02 미래파인켐 주식회사 스타틴의 중간체, 이의 제조방법 및 이를 이용한 로수바스타틴의 제조방법

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Also Published As

Publication number Publication date
BRPI0518647A2 (pt) 2008-12-02
CN101084197A (zh) 2007-12-05
GB0428328D0 (en) 2005-02-02
MX2007007777A (es) 2007-08-14
IL183528A (en) 2012-02-29
EP1871747A2 (en) 2008-01-02
NO20072872L (no) 2007-09-17
WO2006067456A3 (en) 2006-09-21
EP2361906A1 (en) 2011-08-31
NZ555769A (en) 2010-01-29
AU2005317880A1 (en) 2006-06-29
KR20070092307A (ko) 2007-09-12
JP5127460B2 (ja) 2013-01-23
JP2008525407A (ja) 2008-07-17
US8034932B2 (en) 2011-10-11
US20080207903A1 (en) 2008-08-28
WO2006067456A2 (en) 2006-06-29
CN101084197B (zh) 2012-06-13
AU2005317880B2 (en) 2009-05-28
IL183528A0 (en) 2007-09-20
CA2589775A1 (en) 2006-06-29

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