ZA200609422B - Thieno[3,2-b]pyridine-6-carbonitriles as protein kinase inhibitors - Google Patents
Thieno[3,2-b]pyridine-6-carbonitriles as protein kinase inhibitors Download PDFInfo
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- ZA200609422B ZA200609422B ZA200609422A ZA200609422A ZA200609422B ZA 200609422 B ZA200609422 B ZA 200609422B ZA 200609422 A ZA200609422 A ZA 200609422A ZA 200609422 A ZA200609422 A ZA 200609422A ZA 200609422 B ZA200609422 B ZA 200609422B
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- carbon atoms
- aryl
- group
- alkyl
- nitrogen
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/845,710 US7276519B2 (en) | 2002-11-25 | 2004-05-14 | Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200609422B true ZA200609422B (en) | 2008-07-30 |
Family
ID=35149207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200609422A ZA200609422B (en) | 2004-05-14 | 2006-11-13 | Thieno[3,2-b]pyridine-6-carbonitriles as protein kinase inhibitors |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7276519B2 (fr) |
| EP (1) | EP1756117A2 (fr) |
| JP (1) | JP2007537262A (fr) |
| KR (1) | KR20070015575A (fr) |
| CN (1) | CN1950379A (fr) |
| AR (1) | AR050248A1 (fr) |
| AU (1) | AU2005245820A1 (fr) |
| BR (1) | BRPI0511089A (fr) |
| CA (1) | CA2564530A1 (fr) |
| CR (1) | CR8787A (fr) |
| EC (1) | ECSP067087A (fr) |
| GT (1) | GT200500109A (fr) |
| MX (1) | MXPA06012900A (fr) |
| NO (1) | NO20065489L (fr) |
| PA (1) | PA8633201A1 (fr) |
| PE (1) | PE20060355A1 (fr) |
| RU (1) | RU2006137476A (fr) |
| TW (1) | TW200602348A (fr) |
| WO (1) | WO2005113560A2 (fr) |
| ZA (1) | ZA200609422B (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7618964B2 (en) | 2004-12-23 | 2009-11-17 | Hoffmann-La Roche Inc. | Benzamide derivatives, their manufacture and use as pharmaceutical agents |
| CA2589877A1 (fr) * | 2004-12-23 | 2006-06-29 | F. Hoffmann-La Roche Ag | Derives carbamates heterocycliques, leur fabrication et leur utilisation comme agents pharmaceutiques |
| AR056200A1 (es) * | 2005-09-27 | 2007-09-26 | Wyeth Corp | Tieno [2,3-b]piridin-5-carbonitrilos como inhibidores de proteina quinasa |
| US20110105496A1 (en) * | 2005-12-20 | 2011-05-05 | Gamber Gabriel G | Methods For The Treatment Of Myosin Heavy Chain-Mediated Conditions Using 4,7-Dihydrothieno[2,3-B]Pyridine Compounds |
| CA2655128A1 (fr) * | 2006-06-08 | 2007-12-21 | Array Biopharma Inc. | Quinolines et methodes d'utilisation |
| TW200900408A (en) * | 2007-03-02 | 2009-01-01 | Kyowa Hakko Kogyo Kk | Fused pyridine derivative |
| WO2009041591A1 (fr) * | 2007-09-28 | 2009-04-02 | Kyowa Hakko Kirin Co., Ltd. | Dérivé de pyridine fusionnée |
| AR070317A1 (es) * | 2008-02-06 | 2010-03-31 | Osi Pharm Inc | Furo (3,2-c) piridina y tieno (3,2-c) piridinas |
| EP2331530B8 (fr) * | 2008-09-26 | 2013-12-25 | National Health Research Institutes | Composés multicycliques fusionnés en tant qu inhibiteurs des protéines kinases |
| TW201204733A (en) | 2010-06-25 | 2012-02-01 | Kowa Co | Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same |
| CA2863985C (fr) * | 2012-02-09 | 2020-08-11 | Merck Patent Gmbh | Derives de la furo[3,2-b]- et de la thieno[3,2-b] pyridine comme inhibiteurs de tbk1 et ikk |
| MX367055B (es) | 2012-06-26 | 2019-08-02 | Del Mar Pharmaceuticals | El uso de una composición que comprende dianhidrogalactitol, diacetildianhidrogalactitol, y dibromodulcitol, y análogos o derivados de cada uno para el tratamiento de malignidades resistentes a inhibidores de tirosina cinasa. |
| DE102013008118A1 (de) * | 2013-05-11 | 2014-11-13 | Merck Patent Gmbh | Arylchinazoline |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0126970A3 (fr) | 1983-04-27 | 1985-11-06 | Beecham Group Plc | Dérivés de thiénopyridine anxiolytiques et antidépresseurs |
| AR004010A1 (es) * | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| WO1999024440A1 (fr) | 1997-11-11 | 1999-05-20 | Pfizer Products Inc. | Derives de thienopyrimidine et thienopyridine utiles comme agents anticancereux |
| ES2457396T3 (es) * | 1998-09-29 | 2014-04-25 | Wyeth Holdings Llc | 3-Cianoquinolinas sustituidas como inhibidores de las proteínas tirosina quinasas |
| JP3270834B2 (ja) * | 1999-01-27 | 2002-04-02 | ファイザー・プロダクツ・インク | 抗がん剤として有用なヘテロ芳香族二環式誘導体 |
| GB9906566D0 (en) | 1999-03-23 | 1999-05-19 | Zeneca Ltd | Chemical compounds |
| WO2000066583A1 (fr) | 1999-04-21 | 2000-11-09 | American Cyanamid Company | 3-cyano-[1.7], [1.5], et [1.8]-naphthyridine substitues, inhibiteurs des tyrosine kinases |
| DK1242382T3 (da) | 1999-12-29 | 2007-05-07 | Wyeth Corp | Tricycliske proteinkinaseinhibitorer |
| AR035851A1 (es) | 2000-03-28 | 2004-07-21 | Wyeth Corp | 3-cianoquinolinas, 3-ciano-1,6-naftiridinas y 3-ciano-1,7-naftiridinas como inhibidoras de proteina quinasas |
| JP2003535867A (ja) | 2000-06-06 | 2003-12-02 | ファイザー プロダクツ インコーポレイテッド | 抗癌剤として有用なチオフェン誘導体 |
| US20020004511A1 (en) * | 2000-06-28 | 2002-01-10 | Luzzio Michael Joseph | Thiophene derivatives useful as anticancer agents |
| US7253184B2 (en) * | 2000-11-02 | 2007-08-07 | Astrazeneca Ab | 4-Substituted quinolines as antitumor agents |
| CA2810339A1 (fr) | 2001-08-10 | 2003-02-20 | Novartis Ag | Utilisation d'inhibiteurs c-src seuls ou en combinaison avec sti571 pour le traitement de leucemies |
| CL2003002287A1 (es) * | 2002-11-25 | 2005-01-14 | Wyeth Corp | COMPUESTOS DERIVADOS DE TIENO[3,2-b]-PIRIDINA-6-CARBONITRILOS Y TIENEO[2,3-b]-PIRIDINA-5-CARBONITRILOS, COMPOSICION FARMACEUTICA, PROCEDIMIENTO DE PREPARACION Y COMPUESTOS INTERMEDIARIOS, Y SU USO EN EL TRATAMIENTO DEL CANCER, APOPLEJIA, OSTEOPOROSIS |
| GB0420719D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| ES2623221T3 (es) * | 2005-05-20 | 2017-07-10 | Methylgene Inc | Inhibidores de la señalización del receptor de VEGF y del receptor de HGF |
| AR056200A1 (es) * | 2005-09-27 | 2007-09-26 | Wyeth Corp | Tieno [2,3-b]piridin-5-carbonitrilos como inhibidores de proteina quinasa |
-
2004
- 2004-05-14 US US10/845,710 patent/US7276519B2/en not_active Expired - Fee Related
-
2005
- 2005-05-10 EP EP05742281A patent/EP1756117A2/fr not_active Withdrawn
- 2005-05-10 CN CNA2005800147166A patent/CN1950379A/zh active Pending
- 2005-05-10 GT GT200500109A patent/GT200500109A/es unknown
- 2005-05-10 BR BRPI0511089-0A patent/BRPI0511089A/pt not_active IP Right Cessation
- 2005-05-10 MX MXPA06012900A patent/MXPA06012900A/es unknown
- 2005-05-10 KR KR1020067023726A patent/KR20070015575A/ko not_active Application Discontinuation
- 2005-05-10 WO PCT/US2005/016150 patent/WO2005113560A2/fr active Application Filing
- 2005-05-10 AU AU2005245820A patent/AU2005245820A1/en not_active Withdrawn
- 2005-05-10 CA CA002564530A patent/CA2564530A1/fr not_active Abandoned
- 2005-05-10 RU RU2006137476/04A patent/RU2006137476A/ru not_active Application Discontinuation
- 2005-05-10 JP JP2007513251A patent/JP2007537262A/ja active Pending
- 2005-05-12 TW TW094115389A patent/TW200602348A/zh unknown
- 2005-05-12 PE PE2005000531A patent/PE20060355A1/es not_active Application Discontinuation
- 2005-05-13 PA PA20058633201A patent/PA8633201A1/es unknown
- 2005-05-13 AR ARP050101971A patent/AR050248A1/es not_active Application Discontinuation
-
2006
- 2006-11-13 ZA ZA200609422A patent/ZA200609422B/en unknown
- 2006-11-28 NO NO20065489A patent/NO20065489L/no unknown
- 2006-12-05 CR CR8787A patent/CR8787A/es not_active Application Discontinuation
- 2006-12-14 EC EC2006007087A patent/ECSP067087A/es unknown
-
2007
- 2007-09-24 US US11/903,754 patent/US20080070913A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06012900A (es) | 2007-01-26 |
| KR20070015575A (ko) | 2007-02-05 |
| JP2007537262A (ja) | 2007-12-20 |
| CR8787A (es) | 2007-10-02 |
| PA8633201A1 (es) | 2006-05-16 |
| CN1950379A (zh) | 2007-04-18 |
| AU2005245820A1 (en) | 2005-12-01 |
| AR050248A1 (es) | 2006-10-11 |
| EP1756117A2 (fr) | 2007-02-28 |
| BRPI0511089A (pt) | 2007-12-26 |
| RU2006137476A (ru) | 2008-06-20 |
| TW200602348A (en) | 2006-01-16 |
| WO2005113560A3 (fr) | 2006-01-12 |
| CA2564530A1 (fr) | 2005-12-01 |
| NO20065489L (no) | 2006-11-28 |
| WO2005113560A2 (fr) | 2005-12-01 |
| ECSP067087A (es) | 2007-01-26 |
| US7276519B2 (en) | 2007-10-02 |
| PE20060355A1 (es) | 2006-05-11 |
| US20040242883A1 (en) | 2004-12-02 |
| US20080070913A1 (en) | 2008-03-20 |
| GT200500109A (es) | 2005-12-23 |
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