ZA200609407B - Monoclonal antibodies to hepatocyte growth factor - Google Patents

Monoclonal antibodies to hepatocyte growth factor

Info

Publication number
ZA200609407B
ZA200609407B ZA200609407A ZA200609407A ZA200609407B ZA 200609407 B ZA200609407 B ZA 200609407B ZA 200609407 A ZA200609407 A ZA 200609407A ZA 200609407 A ZA200609407 A ZA 200609407A ZA 200609407 B ZA200609407 B ZA 200609407B
Authority
ZA
South Africa
Prior art keywords
growth factor
hepatocyte growth
monoclonal antibodies
pharmaceutical composition
administering
Prior art date
Application number
ZA200609407A
Other languages
English (en)
Inventor
Kim Kyung Jin
Su Yi-Chi
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35320045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200609407(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of ZA200609407B publication Critical patent/ZA200609407B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/4753Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ZA200609407A 2004-04-15 2004-08-13 Monoclonal antibodies to hepatocyte growth factor ZA200609407B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/825,060 US20040208876A1 (en) 2003-04-18 2004-04-15 Monoclonal antibodies to hepatocyte growth factor

Publications (1)

Publication Number Publication Date
ZA200609407B true ZA200609407B (en) 2008-07-30

Family

ID=35320045

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200609407A ZA200609407B (en) 2004-04-15 2004-08-13 Monoclonal antibodies to hepatocyte growth factor

Country Status (26)

Country Link
US (5) US20040208876A1 (de)
EP (2) EP2204191A1 (de)
JP (2) JP4594381B2 (de)
KR (1) KR101072736B1 (de)
CN (1) CN1964738A (de)
AT (1) ATE473760T1 (de)
AU (1) AU2004319276C1 (de)
BR (1) BRPI0418745A (de)
CA (1) CA2563080C (de)
CR (1) CR8698A (de)
CY (1) CY1110783T1 (de)
DE (1) DE602004028168D1 (de)
DK (1) DK1734995T3 (de)
ES (1) ES2346886T3 (de)
HK (1) HK1094167A1 (de)
HR (1) HRP20100521T1 (de)
IL (1) IL178474A (de)
MX (1) MXPA06011822A (de)
NO (1) NO20065227L (de)
NZ (1) NZ550324A (de)
PL (1) PL1734995T3 (de)
PT (1) PT1734995E (de)
RU (1) RU2361879C2 (de)
SI (1) SI1734995T1 (de)
WO (1) WO2005107800A1 (de)
ZA (1) ZA200609407B (de)

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US20040208876A1 (en) * 2003-04-18 2004-10-21 Kim Kyung Jin Monoclonal antibodies to hepatocyte growth factor
TW201319088A (zh) * 2003-07-18 2013-05-16 Amgen Inc 對肝細胞生長因子具專一性之結合劑
WO2006015371A2 (en) * 2004-08-05 2006-02-09 Genentech, Inc. Humanized anti-cmet antagonists
WO2006130773A2 (en) * 2005-06-02 2006-12-07 Galaxy Biotech, Llc Methods of treating brain tumors with antibodies
EP1941907B1 (de) 2005-10-14 2016-03-23 Fukuoka University Mittel zur unterdrückung von transplantations-inselzell-dysfunktion bei inselzelltransplantationen
AU2006305119B2 (en) 2005-10-21 2012-12-20 Chugai Seiyaku Kabushiki Kaisha Agents for treating cardiopathy
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
TW200803894A (en) * 2005-11-25 2008-01-16 Univ Keio Prostate cancer therapeutic agents
EP3135298B1 (de) 2006-01-27 2018-06-06 Keio University Therapeutische mittel für erkrankungen im zusammenhang mit choroidaler neovaskularisation
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
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US7951368B2 (en) * 2007-06-25 2011-05-31 Amgen Inc. Compositions of specific binding agents to hepatocyte growth factor
TW201002346A (en) * 2008-04-11 2010-01-16 Galaxy Biotech Llc Combination of HGF inhibitor and EGF inhibitor to treat cancer
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JP5544290B2 (ja) 2008-06-05 2014-07-09 独立行政法人国立がん研究センター 神経浸潤抑制剤
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
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WO2010119991A2 (en) 2009-04-17 2010-10-21 Takeda Pharmaceutical Company Limited Novel method of treating cancer
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EP2287197A1 (de) * 2009-08-21 2011-02-23 Pierre Fabre Medicament Anti-cMET-Antikörper und seine Verwendung zur Erkennung und Diagnose von Krebs
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JP2013532627A (ja) 2010-07-01 2013-08-19 武田薬品工業株式会社 cMET阻害剤とHGFおよび/またはcMETに対する抗体との組み合わせ
JP2013537918A (ja) 2010-09-27 2013-10-07 エクセリクシス, インク. 去勢抵抗性前立腺癌および骨芽細胞骨転移の治療のためのmetおよびvegfの二元阻害薬
US20130004484A1 (en) 2011-06-30 2013-01-03 Genentech, Inc. Anti-c-met antibody formulations
CZ303636B6 (cs) * 2011-08-19 2013-01-23 Invos, Spol. S R. O. Biokontejner pro sber bioodpadu a komunálního odpadu
WO2013036872A1 (en) 2011-09-09 2013-03-14 Amgen Inc. Use of c-met protein for predicting the efficacy of anti-hepatocyte growth factor ("hgf") antibodies in esophageal and gastric cancer patients
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WO2014010586A1 (ja) 2012-07-10 2014-01-16 武田薬品工業株式会社 注射用製剤
US9931400B2 (en) 2012-09-12 2018-04-03 Samsung Electronics Co., Ltd. Method of combination therapy for prevention or treatment of c-Met or angiogenesis factor induced diseases
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WO2006130773A2 (en) 2005-06-02 2006-12-07 Galaxy Biotech, Llc Methods of treating brain tumors with antibodies
AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos

Also Published As

Publication number Publication date
WO2005107800A1 (en) 2005-11-17
US20070160613A1 (en) 2007-07-12
MXPA06011822A (es) 2007-03-23
JP4594381B2 (ja) 2010-12-08
CN1964738A (zh) 2007-05-16
DK1734995T3 (da) 2010-10-25
DE602004028168D1 (de) 2010-08-26
IL178474A0 (en) 2007-02-11
IL178474A (en) 2011-04-28
ES2346886T3 (es) 2010-10-21
CA2563080A1 (en) 2005-11-17
HK1094167A1 (en) 2007-03-23
US20120064066A1 (en) 2012-03-15
CY1110783T1 (el) 2015-06-10
RU2361879C2 (ru) 2009-07-20
US7687063B2 (en) 2010-03-30
PL1734995T3 (pl) 2010-12-31
BRPI0418745A (pt) 2007-12-11
SI1734995T1 (sl) 2010-09-30
US20040208876A1 (en) 2004-10-21
US20090104192A1 (en) 2009-04-23
KR101072736B1 (ko) 2011-10-11
HRP20100521T1 (hr) 2010-10-31
AU2004319276B2 (en) 2010-08-26
NO20065227L (no) 2007-01-10
KR20070012711A (ko) 2007-01-26
AU2004319276C1 (en) 2011-03-03
EP1734995A1 (de) 2006-12-27
JP2011012067A (ja) 2011-01-20
PT1734995E (pt) 2010-08-18
RU2006140257A (ru) 2008-05-20
ATE473760T1 (de) 2010-07-15
US20080019966A1 (en) 2008-01-24
EP1734995A4 (de) 2007-04-25
NZ550324A (en) 2009-12-24
JP2007532643A (ja) 2007-11-15
EP2204191A1 (de) 2010-07-07
CR8698A (es) 2007-12-17
AU2004319276A1 (en) 2005-11-17
US7494650B2 (en) 2009-02-24
EP1734995B1 (de) 2010-07-14
CA2563080C (en) 2015-01-27

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