ZA200606963B - Dry powder preparations for pre-metered DPI - Google Patents
Dry powder preparations for pre-metered DPI Download PDFInfo
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- ZA200606963B ZA200606963B ZA200606963A ZA200606963A ZA200606963B ZA 200606963 B ZA200606963 B ZA 200606963B ZA 200606963 A ZA200606963 A ZA 200606963A ZA 200606963 A ZA200606963 A ZA 200606963A ZA 200606963 B ZA200606963 B ZA 200606963B
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- dose
- preparation
- particles
- metered
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- 239000000843 powder Substances 0.000 title claims abstract description 111
- 238000002360 preparation method Methods 0.000 title claims abstract description 77
- 239000002245 particle Substances 0.000 claims abstract description 90
- 238000000034 method Methods 0.000 claims abstract description 67
- 239000003814 drug Substances 0.000 claims abstract description 59
- 238000011049 filling Methods 0.000 claims abstract description 39
- 229940112141 dry powder inhaler Drugs 0.000 claims abstract description 31
- 238000011068 loading method Methods 0.000 claims abstract description 22
- 230000005520 electrodynamics Effects 0.000 claims abstract description 14
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- 239000002831 pharmacologic agent Substances 0.000 claims abstract description 12
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
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- A—HUMAN NECESSITIES
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- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400844A SE528121C2 (sv) | 2004-03-29 | 2004-03-29 | Preparering av torrpulver för på förhand uppmätt DPI |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200606963B true ZA200606963B (en) | 2007-11-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200606963A ZA200606963B (en) | 2004-03-29 | 2005-03-23 | Dry powder preparations for pre-metered DPI |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20050211244A1 (de) |
| EP (1) | EP1732515B1 (de) |
| JP (1) | JP2007530671A (de) |
| CN (1) | CN1933815A (de) |
| AT (1) | ATE399534T1 (de) |
| AU (1) | AU2005225335A1 (de) |
| CA (1) | CA2556443A1 (de) |
| DE (1) | DE602005007876D1 (de) |
| DK (1) | DK1732515T3 (de) |
| ES (1) | ES2311217T3 (de) |
| MX (1) | MXPA06009286A (de) |
| RU (1) | RU2006131829A (de) |
| SE (1) | SE528121C2 (de) |
| WO (1) | WO2005092289A1 (de) |
| ZA (1) | ZA200606963B (de) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0327723D0 (en) | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| EA016072B1 (ru) * | 2005-05-18 | 2012-01-30 | Палметрикс Инк. | Применение состава соли кальция для изменения биофизических свойств слизистой оболочки |
| US20070101991A1 (en) * | 2005-11-08 | 2007-05-10 | Mederio Ag | Optimizing release of dry medicament powder |
| AU2006318620B2 (en) * | 2005-11-21 | 2012-04-05 | Mannkind Corporation | Powder dispensing and sensing apparatus and methods |
| GB0616299D0 (en) * | 2006-08-16 | 2006-09-27 | Cambridge Consultants | Drug Capsules for dry power inhalers |
| US7908992B2 (en) * | 2007-01-09 | 2011-03-22 | R.P. Scherer Technologies, Llc | System and method for dusting soft capsules |
| US20110077272A1 (en) * | 2008-02-01 | 2011-03-31 | Vectura Limited | Pulmonary formulations of triptans |
| MX2011001421A (es) | 2008-08-05 | 2011-04-04 | Mannkind Corp | Modulos surtidores de polvo y ensambles surtidores de polvo mejorados. |
| AU2010229668C1 (en) | 2009-03-26 | 2016-09-15 | Pulmatrix Operating Co., Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| GB0905840D0 (en) * | 2009-04-06 | 2009-05-20 | Sagentia Ltd | Apparatus and methods |
| US8758824B2 (en) | 2010-08-30 | 2014-06-24 | Pulmatrix, Inc. | Respirably dry powder comprising calcium lactate, sodium chloride and leucine |
| AU2011296343B2 (en) | 2010-08-30 | 2015-12-10 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| ES2899621T3 (es) | 2010-09-29 | 2022-03-14 | Pulmatrix Operating Co Inc | Polvos secos catiónicos que comprenden sal de magnesio |
| RU2017144619A (ru) | 2010-09-29 | 2019-02-20 | Пулмэтрикс, Инк. | Катионы одновалентных металлов сухих порошков для ингаляций |
| WO2013130767A1 (en) | 2012-02-29 | 2013-09-06 | Pulmatrix, Inc. | Inhalable dry powders |
| US10105316B2 (en) | 2012-07-05 | 2018-10-23 | Arven llac Sanayi Ve Ticaret A.S. | Inhalation compositions comprising muscarinic receptor antagonist |
| US20150165037A1 (en) * | 2012-07-05 | 2015-06-18 | Arven llac Sanayi Ve Ticaret A.S. | Inhalation compositions comprising corticosteroid and sorbitol |
| US10111957B2 (en) | 2012-07-05 | 2018-10-30 | Arven Ilac Snayi ve Ticaret A.S. | Inhalation compositions comprising glucose anhydrous |
| AU2014248455B2 (en) | 2013-04-01 | 2018-12-06 | Pulmatrix Operating Company, Inc. | Tiotropium dry powders |
| CN103287602A (zh) * | 2013-06-27 | 2013-09-11 | 顺天保暖制品（昆山）有限公司 | 一种包装机上的分体式量杯 |
| CN105828819A (zh) * | 2014-04-08 | 2016-08-03 | 桑萨（巴巴多斯）公司 | 烟碱制剂及其制备方法 |
| WO2016067252A1 (en) | 2014-10-31 | 2016-05-06 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
| US10149844B2 (en) | 2015-09-16 | 2018-12-11 | Philip Morris Products S.A. | Inhalable nicotine formulations, and methods of making and using thereof |
| US20170071248A1 (en) * | 2015-09-16 | 2017-03-16 | Sansa Corporation (Barbados) Inc. | System and Method for Controlling the Harshness of Nicotine-Based Dry Powder Formulations |
| US9585835B1 (en) | 2015-09-16 | 2017-03-07 | Sansa Corporation (Barbados) Inc. | Inhalable nicotine formulations and methods of making and using the same |
| EP3327409B1 (de) * | 2016-11-29 | 2019-09-11 | Mettler-Toledo GmbH | Automatisiertes dosierungsausgabesystem für pulverförmige substanzen und verfahren zur bestimmung ob das system bereit für den betrieb ist |
| CN111278404B (zh) * | 2017-09-21 | 2023-05-09 | 豪夫迈·罗氏有限公司 | 制药设施和药物产品的制造方法 |
| EP3691616A1 (de) * | 2017-10-02 | 2020-08-12 | Novartis AG | Verfahren zur herstellung eines pharmazeutischen produkts |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3860618A (en) * | 1967-08-08 | 1975-01-14 | Philip Saxton Hartley | Chromone |
| US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
| US6536427B2 (en) * | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| US6794357B1 (en) * | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
| HU222355B1 (hu) * | 1993-10-01 | 2003-06-28 | Astra Aktiebolag | Eljárás és berendezés finom gyógyszerhatóanyag-porok kezelésére és feldolgozására |
| SE9400462D0 (sv) * | 1994-02-11 | 1994-02-11 | Astra Ab | Filling device |
| DK1393721T3 (da) * | 1997-03-20 | 2009-03-30 | Schering Corp | Doseringsform af pulveragglomerater |
| GB9911770D0 (en) * | 1999-05-21 | 1999-07-21 | Glaxo Group Ltd | Powder loading method |
| MXPA02003645A (es) * | 1999-10-11 | 2003-07-28 | Ml Lab Plc | Aparato suministrador de medicamento con revestimiento resistente a la humedad. |
| PT1666028E (pt) * | 1999-10-29 | 2010-06-15 | Novartis Ag | Composições de pós anidros com melhor dispersividade |
| DK1280520T4 (en) * | 2000-05-10 | 2018-06-25 | Novartis Ag | Phospholipid based powders for drug delivery |
| GB0014082D0 (en) * | 2000-06-10 | 2000-08-02 | Glaxo Group Ltd | Method and apparatus for transferring a defined quantity of powder |
| SE0003082L (sv) * | 2000-08-31 | 2002-01-29 | Microdrug Ag | Uppmätt elektrodos |
| SE517227C2 (sv) * | 2000-09-25 | 2002-05-14 | Microdrug Ag | Inhalator för torrt pulver med folieskärare |
| SE522558C2 (sv) * | 2001-07-13 | 2004-02-17 | Microdrug Ag | Förfarande och anordning för styrning av överföring av elektriskt laddade partiklar av ett medicinskt pulver till en målarea på ett substratelement vid en dosutformningsprocess |
| US7931022B2 (en) * | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
| GB0202912D0 (en) * | 2002-02-07 | 2002-03-27 | Meridica Ltd | Method and apparatus for introducing powder into a pocket |
| SE524990C2 (sv) * | 2002-04-12 | 2004-11-09 | Microdrug Ag | Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver |
| GB0225621D0 (en) * | 2002-11-02 | 2002-12-11 | Glaxo Group Ltd | Medicament carrier |
-
2004
- 2004-03-29 SE SE0400844A patent/SE528121C2/sv not_active IP Right Cessation
-
2005
- 2005-03-22 US US11/085,523 patent/US20050211244A1/en not_active Abandoned
- 2005-03-23 DE DE602005007876T patent/DE602005007876D1/de not_active Expired - Fee Related
- 2005-03-23 MX MXPA06009286A patent/MXPA06009286A/es not_active Application Discontinuation
- 2005-03-23 CA CA002556443A patent/CA2556443A1/en not_active Abandoned
- 2005-03-23 JP JP2007506106A patent/JP2007530671A/ja active Pending
- 2005-03-23 EP EP05722259A patent/EP1732515B1/de not_active Revoked
- 2005-03-23 CN CN200580009403.1A patent/CN1933815A/zh active Pending
- 2005-03-23 ZA ZA200606963A patent/ZA200606963B/en unknown
- 2005-03-23 AU AU2005225335A patent/AU2005225335A1/en not_active Abandoned
- 2005-03-23 WO PCT/SE2005/000418 patent/WO2005092289A1/en active Application Filing
- 2005-03-23 AT AT05722259T patent/ATE399534T1/de not_active IP Right Cessation
- 2005-03-23 RU RU2006131829/15A patent/RU2006131829A/ru not_active Application Discontinuation
- 2005-03-23 DK DK05722259T patent/DK1732515T3/da active
- 2005-03-23 ES ES05722259T patent/ES2311217T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SE528121C2 (sv) | 2006-09-05 |
| DE602005007876D1 (de) | 2008-08-14 |
| EP1732515A1 (de) | 2006-12-20 |
| WO2005092289A1 (en) | 2005-10-06 |
| ES2311217T3 (es) | 2009-02-01 |
| CA2556443A1 (en) | 2005-10-06 |
| US20050211244A1 (en) | 2005-09-29 |
| MXPA06009286A (es) | 2007-03-07 |
| CN1933815A (zh) | 2007-03-21 |
| EP1732515B1 (de) | 2008-07-02 |
| RU2006131829A (ru) | 2008-05-10 |
| SE0400844D0 (sv) | 2004-03-29 |
| ATE399534T1 (de) | 2008-07-15 |
| AU2005225335A1 (en) | 2005-10-06 |
| SE0400844L (sv) | 2005-09-30 |
| DK1732515T3 (da) | 2008-11-10 |
| JP2007530671A (ja) | 2007-11-01 |
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