ZA200606102B - Tissue system with undifferentiated stem cells derived from corneal limbus - Google Patents

Tissue system with undifferentiated stem cells derived from corneal limbus

Info

Publication number
ZA200606102B
ZA200606102B ZA200606102A ZA200606102A ZA200606102B ZA 200606102 B ZA200606102 B ZA 200606102B ZA 200606102 A ZA200606102 A ZA 200606102A ZA 200606102 A ZA200606102 A ZA 200606102A ZA 200606102 B ZA200606102 B ZA 200606102B
Authority
ZA
South Africa
Prior art keywords
stem cells
cells derived
undifferentiated stem
tissue system
corneal limbus
Prior art date
Application number
ZA200606102A
Other languages
English (en)
Inventor
Totey Satish Mahadeorao
Kashyap Sudhadra Devi
Original Assignee
Reliance Life Sciences Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reliance Life Sciences Pvt Ltd filed Critical Reliance Life Sciences Pvt Ltd
Publication of ZA200606102B publication Critical patent/ZA200606102B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA200606102A 2004-01-27 2006-07-24 Tissue system with undifferentiated stem cells derived from corneal limbus ZA200606102B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN74MU2004 2004-01-27

Publications (1)

Publication Number Publication Date
ZA200606102B true ZA200606102B (en) 2007-11-28

Family

ID=34856876

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200606102A ZA200606102B (en) 2004-01-27 2006-07-24 Tissue system with undifferentiated stem cells derived from corneal limbus

Country Status (10)

Country Link
US (1) US20050186672A1 (zh)
EP (1) EP1733026A4 (zh)
JP (1) JP2007524411A (zh)
KR (1) KR20070001108A (zh)
CN (1) CN100554411C (zh)
BR (1) BRPI0506474A (zh)
CA (1) CA2554691A1 (zh)
SG (1) SG151246A1 (zh)
WO (1) WO2005079145A2 (zh)
ZA (1) ZA200606102B (zh)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2182005B1 (en) 2000-06-05 2015-03-25 The Brigham & Women's Hospital, Inc. A gene encoding a multidrug resistance human P-glycoprotein homologue on chromosome 7p15-21 and uses thereof
US20060183102A1 (en) * 2005-02-14 2006-08-17 Young Henry E Serum-free reagents for the isolation, cultivation, and cryopreservation of postnatal pluripotent epiblast-like stem cells
US20090170059A1 (en) * 2005-11-14 2009-07-02 Hans Klingemann Methods for Preparing Cord Matrix Stem Cells (CMSC) for Long Term Storage and for Preparing a Segment of umbilical cord for cryopreservation
US8455250B2 (en) 2005-12-29 2013-06-04 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
EP1987133A2 (en) * 2006-02-24 2008-11-05 Reliance Life Sciences Pvt., Ltd. Conjunctival tissue system
KR100908481B1 (ko) * 2006-04-24 2009-07-21 코아스템(주) 중간엽 줄기세포 배양 배지 및 이를 이용한 중간엽줄기세포의 배양 방법
ES2511791T3 (es) 2006-05-31 2014-10-23 Children's Medical Center Corporation Células madre mesenquimales positivas para ABCB5 como moduladoras de inmunidad
WO2008024832A2 (en) * 2006-08-24 2008-02-28 Cedars-Sinai Medical Center Methods for isolating and using pituitary adenoma stem cells and pituitary adenoma cells
WO2008067408A2 (en) * 2006-11-28 2008-06-05 Cedars-Sinai Medical Center Method of isolating and propagating stem cells from benign tumors
AU2008243302A1 (en) * 2007-04-26 2008-11-06 Medinnova As Transplant storage
WO2010043076A1 (zh) * 2008-10-17 2010-04-22 宁夏医科大学附属医院 适于临床应用的人胎盘间质细胞库的建立方法
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
WO2010104696A1 (en) * 2009-03-11 2010-09-16 Invitrx, Inc. Method and composition for the treatment of moderate to severe keratoconjunctivitis sicca
EP2309003A1 (en) * 2009-09-18 2011-04-13 Bioftalmik, S.L. Method for the diagnosis of limbal stem cell deficiency
WO2011060135A1 (en) 2009-11-12 2011-05-19 Vbi Technologies, Llc Subpopulations of spore-like cells and uses thereof
KR101202836B1 (ko) * 2010-08-27 2012-11-20 서울대학교산학협력단 세포응집을 이용한 인간 혈액 유래 혈구 세포괴의 유도와 이를 이용한 혈중 성체줄기세포 및 전구세포의 증폭방법 및 상기의 방법에 의해 제조된 줄기세포
EP2700709A4 (en) * 2011-04-20 2014-11-19 Univ Osaka IPS CELL HAVING PREDISPOSITION FOR CORNEAL EPITHELIUM DIFFERENTIATION
RU2475218C1 (ru) * 2011-12-06 2013-02-20 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" Способ выделения и органо-типической консервации аллогенного лимбального трансплантата
WO2013184843A1 (en) * 2012-06-05 2013-12-12 The Regents Of The University Of California Novel methods to regenerate human limbal stem cells
US10265161B2 (en) 2012-08-07 2019-04-23 Regeneye L. L. C. Ocular collar stent for treating narrowing of the irideocorneal angle
US9308082B2 (en) 2012-08-07 2016-04-12 RegenEye, L.L.C. Ocular collar stent for treating narrowing of the irideocorneal angle
US9974645B2 (en) 2012-08-07 2018-05-22 RegenEye, L.L.C. Method of reducing the occurrence of macular and neuroretinal degenerations by alleviating age related retinal stresses as a contributing factor in a mammalian eye
AU2014219026B2 (en) * 2013-02-19 2018-11-29 Children's Medical Center Corporation ABCB5(+) stem cells for treating ocular disease
CA2953524A1 (en) * 2014-06-27 2015-12-30 The Regents Of The University Of California Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
KR101645901B1 (ko) * 2015-12-31 2016-08-04 가톨릭대학교 산학협력단 양막 슬라이드 지지체를 이용한 윤부줄기세포 배양방법
CN105797138A (zh) * 2016-03-29 2016-07-27 深圳爱生再生医学科技有限公司 修复角膜的干细胞制剂及其制备方法和应用
CN106039289A (zh) * 2016-05-26 2016-10-26 深圳爱生再生医学科技有限公司 干细胞制剂及其制备方法
MX2019006576A (es) 2016-12-07 2019-08-21 Mayo Found Medical Education & Res Metodos y materiales para usar soportes de fibrina para trasplante de epitelio de pigmento retiniano.
KR102241349B1 (ko) * 2017-01-13 2021-04-15 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 각막상피세포 집단의 제조 방법
CN110709504A (zh) * 2017-06-05 2020-01-17 梅约医学教育与研究基金会 培养、增殖和分化干细胞的方法和材料
EP3645068A4 (en) * 2017-06-30 2021-04-07 Vascudyne Inc REGENERATIVE AND NATURAL FABRIC IMPLANTS
WO2020018868A1 (en) 2018-07-19 2020-01-23 Texas Tech University System Corneal epithelial cells and their products for treating corneal diseases
CN109321527A (zh) * 2018-10-10 2019-02-12 中国海洋大学 角膜缘干细胞稳定性的体外培养方法
CN111700912B (zh) * 2020-06-03 2022-04-19 青岛海尔生物科技有限公司 一种适用于角膜缘干细胞缺乏症的滴眼液及制备
CN111657269B (zh) * 2020-06-22 2022-02-08 镇江雷音再生医学科技有限公司 纤维蛋白胶用于smile来源人角膜透镜保存前的保护处理方法
CN113106057B (zh) * 2020-12-23 2023-04-25 重庆医科大学附属儿童医院 一种用于肝细胞移植的自体干细胞制剂及制备方法
CN112626019A (zh) * 2020-12-28 2021-04-09 武汉爱尔眼科医院有限公司 一种眼角膜及角膜缘单细胞悬液的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703047A (en) * 1992-09-21 1997-12-30 Board Of Regents, The University Of Texas System Methods and treatments for corneal healing with growth factors
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US7410798B2 (en) * 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US20030161817A1 (en) * 2001-03-28 2003-08-28 Young Henry E. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
US20020039788A1 (en) * 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
US6921665B2 (en) * 2000-11-27 2005-07-26 Roslin Institute (Edinburgh) Selective antibody targeting of undifferentiated stem cells
US20040015617A1 (en) * 2001-01-25 2004-01-22 Sangha Onkar S. Flexible network interfaces and flexible data clocking
US7347876B2 (en) * 2001-04-25 2008-03-25 Ray Jui-Fang Tsai Method for expansion of epithelial stem cells
ITRM20010476A1 (it) * 2001-08-03 2003-02-03 Idi Irccs Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.
EP1425388A2 (en) * 2001-09-12 2004-06-09 DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung A method for isolating, culturing and differentiating intestinal stem cells for therapeutic use
WO2003089619A2 (en) * 2002-04-19 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Placental derived stem cells and uses thereof
ITUD20020092A1 (it) 2002-04-30 2002-07-30 Univ Degli Studi Udine Metodo per l'identificazione e l'isolamento di cellule staminali di un tessuto umano
US7422736B2 (en) * 2002-07-26 2008-09-09 Food Industry Research And Development Institute Somatic pluripotent cells
US20050136536A1 (en) * 2003-09-15 2005-06-23 Anderson Daniel G. Embryonic epithelial cells
KR20080036636A (ko) * 2004-02-26 2008-04-28 리라이언스 라이프 사이언시스 프라이빗. 리미티드 각막 윤부에서 유도된 다능성 배아 유사 줄기 세포, 분리방법 및 이들의 용도
US20090253151A1 (en) * 2006-09-01 2009-10-08 Stempeutics Research Private Limited Self-Renewing Master Adult Pluripotent Stem Cells

Also Published As

Publication number Publication date
CA2554691A1 (en) 2005-09-01
JP2007524411A (ja) 2007-08-30
WO2005079145A3 (en) 2007-05-03
CN100554411C (zh) 2009-10-28
KR20070001108A (ko) 2007-01-03
US20050186672A1 (en) 2005-08-25
WO2005079145A2 (en) 2005-09-01
SG151246A1 (en) 2009-04-30
BRPI0506474A (pt) 2007-02-06
WO2005079145A8 (en) 2006-04-13
CN101052299A (zh) 2007-10-10
EP1733026A2 (en) 2006-12-20
EP1733026A4 (en) 2009-06-03

Similar Documents

Publication Publication Date Title
ZA200606102B (en) Tissue system with undifferentiated stem cells derived from corneal limbus
GB2440333B (en) Synthetic cornea from retinal stem cells derived from human parthenotes
HK1212197A1 (zh) 可變形的角膜植入物
EP1809207A4 (en) ARTIFICIAL CORNEEN IMPLANT
EP1874234A4 (en) ARTIFICIAL HORN SKIN
EP1732484A4 (en) OPHTHALMIC IMPLANT FOR THE TREATMENT OF GLAUCOMA
EP1809740A4 (en) CARDIAC STEM CELLS
IL181438A0 (en) Culturing human embryonic stem cells
EP1740262A4 (en) MICRO-SURGERY TISSUE TREATMENT SYSTEM
EP1812556A4 (en) NEURONAL PRECURSORS OF FEEDER-FREE HUMAN EMBRYONIC STEM CELL CULTURE
EP2183358A4 (en) PROCESS FOR THE PREPARATION OF DERMAL PAPER TISSUE EMPLOYING MESENCHYMAL STEM CELLS
PL1988865T3 (pl) Układ kontaktowy z rogówką
HK1103106A1 (en) Medium for growing human embryonic stem cells
AP2241A (en) Pyrimidine derivatives for the treatment of abnormal cell growth.
IL180170A0 (en) Flow regulating implants
ZA200607084B (en) Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
WO2007125420A3 (en) Stem cells derived from bone marrow for tissue regeneration
EP1862153A4 (en) OPHTHALMIC CANNULA
HK1120830A1 (en) Modulation of 11beta-hydroxysteroid dehydrogenase 1 expression for the treatment of ocular diseases
EP2063902A4 (en) THERAPEUTIC CELL MEDICAMENT WITH STEM CELLS OF SKIN
IL177672A0 (en) Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
EP1637589A4 (en) NEW STEM CELL DERIVED FROM ADULT FABRIC AND THEIR USE
GB0523961D0 (en) The treatment of ophthalmic diseases
HU0401385D0 (en) Tissue cultivating method for culturing skin cells
EP1768656A4 (en) TREATMENT OF OCULAR DISEASES