ITRM20010476A1 - Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento. - Google Patents

Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.

Info

Publication number
ITRM20010476A1
ITRM20010476A1 IT2001RM000476A ITRM20010476A ITRM20010476A1 IT RM20010476 A1 ITRM20010476 A1 IT RM20010476A1 IT 2001RM000476 A IT2001RM000476 A IT 2001RM000476A IT RM20010476 A ITRM20010476 A IT RM20010476A IT RM20010476 A1 ITRM20010476 A1 IT RM20010476A1
Authority
IT
Italy
Prior art keywords
reconstructed
obtaining
corneal epithelium
human corneal
sheets
Prior art date
Application number
IT2001RM000476A
Other languages
English (en)
Inventor
Luca Michele De
Graziella Pellegrini
Original Assignee
Idi Irccs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idi Irccs filed Critical Idi Irccs
Priority to IT2001RM000476A priority Critical patent/ITRM20010476A1/it
Publication of ITRM20010476A0 publication Critical patent/ITRM20010476A0/it
Priority to US09/961,314 priority patent/US6610538B2/en
Priority to DK01274401T priority patent/DK1451302T3/da
Priority to PT01274401T priority patent/PT1451302E/pt
Priority to DE60134280T priority patent/DE60134280D1/de
Priority to AT01274401T priority patent/ATE397058T1/de
Priority to EP01274401A priority patent/EP1451302B1/en
Priority to PCT/IT2001/000603 priority patent/WO2003012083A1/en
Priority to ES01274401T priority patent/ES2307570T3/es
Publication of ITRM20010476A1 publication Critical patent/ITRM20010476A1/it
Priority to CY20081100854T priority patent/CY1108257T1/el
Priority to NL300754C priority patent/NL300754I2/nl
Priority to FR15C0055C priority patent/FR15C0055I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/56—Fibrin; Thrombin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT2001RM000476A 2001-08-03 2001-08-03 Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento. ITRM20010476A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT2001RM000476A ITRM20010476A1 (it) 2001-08-03 2001-08-03 Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.
US09/961,314 US6610538B2 (en) 2001-08-03 2001-09-25 Reconstructed laminae of human epithelium corneae and method of producing the same
ES01274401T ES2307570T3 (es) 2001-08-03 2001-11-28 Laminas de epitelio corneal humano reconstituidas in vitro y procedimiento para su produccion.
DE60134280T DE60134280D1 (de) 2001-08-03 2001-11-28 In vitro rekonstituierte lagen des menschlichen ho
PT01274401T PT1451302E (pt) 2001-08-03 2001-11-28 Folhas reconstituídas in vitro de epitélio corneal humano e método de produção das mesmas
DK01274401T DK1451302T3 (da) 2001-08-03 2001-11-28 In vitro rekonstituerede lag af humant hornhindeepitel samt fremgangsmåde til fremstilling deraf
AT01274401T ATE397058T1 (de) 2001-08-03 2001-11-28 In vitro rekonstituierte lagen des menschlichen hornhautepithels und verfahren zur herstellung davon
EP01274401A EP1451302B1 (en) 2001-08-03 2001-11-28 In vitro reconstituted sheets of human corneal epithelium and method of producing the same
PCT/IT2001/000603 WO2003012083A1 (en) 2001-08-03 2001-11-28 In vitro reconstituted sheets of human corneal epithelium and method of producing the same
CY20081100854T CY1108257T1 (el) 2001-08-03 2008-08-12 In vitro ανασυσταμενες στιβαδες ανθρωπινου κερατοειδικου επιθηλιου και μεθοδος παραγωγης αυτων
NL300754C NL300754I2 (it) 2001-08-03 2015-07-23
FR15C0055C FR15C0055I2 (fr) 2001-08-03 2015-07-29 Feuillets de l'epithelium corneen humain reconstitues in vitro et methode de production de ces derniers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001RM000476A ITRM20010476A1 (it) 2001-08-03 2001-08-03 Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.

Publications (2)

Publication Number Publication Date
ITRM20010476A0 ITRM20010476A0 (it) 2001-08-03
ITRM20010476A1 true ITRM20010476A1 (it) 2003-02-03

Family

ID=11455714

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2001RM000476A ITRM20010476A1 (it) 2001-08-03 2001-08-03 Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.

Country Status (12)

Country Link
US (1) US6610538B2 (it)
EP (1) EP1451302B1 (it)
AT (1) ATE397058T1 (it)
CY (1) CY1108257T1 (it)
DE (1) DE60134280D1 (it)
DK (1) DK1451302T3 (it)
ES (1) ES2307570T3 (it)
FR (1) FR15C0055I2 (it)
IT (1) ITRM20010476A1 (it)
NL (1) NL300754I2 (it)
PT (1) PT1451302E (it)
WO (1) WO2003012083A1 (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186672A1 (en) * 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
KR100931887B1 (ko) * 2004-02-26 2009-12-15 리라이언스 라이프 사이언시스 프라이빗. 리미티드 각막 윤부에서 유도된 다능성 배아 유사 줄기 세포, 분리 방법 및 이들의 용도
US8187875B2 (en) * 2004-02-26 2012-05-29 Reliance Life Sciences Pvt. Ltd. Dopaminergic neurons derived from corneal limbus, methods of isolation and uses thereof
US20060216821A1 (en) * 2004-02-26 2006-09-28 Reliance Life Sciences Pvt. Ltd. Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
ITRM20040273A1 (it) * 2004-06-03 2004-09-03 Farmigea Spa Metodo per l'isolamento e l'espansione ex vivo di cellule staminali corneali umane e loro relativi usi.
KR20080097226A (ko) * 2006-02-24 2008-11-04 리라이언스 라이프 사이언시스 프라이빗. 리미티드 결막 조직 시스템
WO2011040888A1 (en) * 2009-10-01 2011-04-07 Singapore Health Services Pte Ltd A biodegradable composition or combination and uses thereof
RU2505303C2 (ru) * 2011-09-13 2014-01-27 Общество с ограниченной ответственностью "Офтальмологические биотехнологии" Способ получения биотрансплантата для роговицы
FR2993282B1 (fr) 2012-07-13 2017-11-10 Expanscience Lab Procede d'identification de marqueurs moleculaires de la peau d'enfant
FR3011008B1 (fr) 2013-09-24 2017-12-29 Expanscience Lab Procedes d'evaluation des effets deleteres des uv sur la peau d'enfant
FR3016373B1 (fr) 2014-01-10 2018-01-19 Laboratoires Expanscience Modele de peau de mammelon reconstitue
FR3019186B1 (fr) 2014-03-31 2019-06-07 Laboratoires Expanscience Procedes d'evaluation des effets deleteres de l'urine sur la peau d'enfant
FR3045669B1 (fr) 2015-12-16 2019-04-05 Laboratoires Expanscience Procedes d'evaluation des effets de la deshydratation sur la peau d'enfant
FR3053053B1 (fr) 2016-06-23 2018-07-13 Laboratoires Expanscience Modeles de la dermatite atopique juvenile
FR3068045B1 (fr) 2017-06-22 2021-06-04 Expanscience Lab Modeles de peau sensible reconstituee
WO2020081934A1 (en) * 2018-10-19 2020-04-23 Regents Of The University Of Minnesota Methods of isolating and using descemet's membrane and compositions including isolated descemet's membrane
FR3133198A1 (fr) 2022-03-04 2023-09-08 Pierre Fabre Dermo-Cosmetique Modele de peau reconstituee
FR3138149A1 (fr) 2022-07-25 2024-01-26 Pierre Fabre Dermo-Cosmetique Méthode d’évaluation in vitro de l’activité photoprotectrice d’un actif

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255657B (it) 1992-05-29 1995-11-09 Colture di tessuto di mucosa congiuntivale differenziata, procedimentoper la loro preparazione e supporti per il loro uso.
US5827641A (en) 1992-11-13 1998-10-27 Parenteau; Nancy L. In vitro cornea equivalent model
CA2227827A1 (en) 1998-01-23 1999-07-23 Unknown In vitro artificial cornea and sclera

Also Published As

Publication number Publication date
NL300754I2 (it) 2016-09-01
FR15C0055I1 (it) 2015-09-11
FR15C0055I2 (fr) 2016-06-24
ES2307570T3 (es) 2008-12-01
EP1451302A1 (en) 2004-09-01
DK1451302T3 (da) 2008-09-08
WO2003012083A1 (en) 2003-02-13
US6610538B2 (en) 2003-08-26
EP1451302B1 (en) 2008-05-28
PT1451302E (pt) 2008-09-08
US20030027333A1 (en) 2003-02-06
CY1108257T1 (el) 2014-02-12
DE60134280D1 (de) 2008-07-10
ATE397058T1 (de) 2008-06-15
ITRM20010476A0 (it) 2001-08-03

Similar Documents

Publication Publication Date Title
FR15C0055I1 (it)
WO2002091999A3 (en) Treatment for wounds
CA2407439A1 (en) Individual venous valve prosthesis
WO2004070013A3 (en) Use of islet 1 as a marker for isolating or generating stem cells
HUP0401542A2 (hu) Follisztatin alkalmazása izomtömeg növelésére
AU2002236795A1 (en) Compositions and method of tissue superoxygenation
GB2393734A (en) Cells of the cardiomyocyte lineage produced from human pluripotent stem cells
AU2003220300A1 (en) Compositions useful as inhibitors of protein kinases
CY1116768T1 (el) Συνθεσεις οι οποιες περιεχουν βλαστοκυτταρα θηλυκης γαμετικης σειρας και μεθοδοι χρησης αυτων
PL356846A1 (en) Use of interleukin-6 antagonists for the treatment of diseases characterised by high levels of aromatase
NZ596420A (en) Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies
EA200400482A1 (ru) Кератиноциты, пригодные для применения в качестве биологически активной субстанции при лечении ран
NO20090068L (no) Aktive agent formuleringer, fremstillingsmetoder, og anvendelsesmetoder
CY1116164T1 (el) Προδρομη 4-σουλφαταση ν-ακετυλογαλακτο σαμινης, μεθοδοι θεραπευτικης αγωγης που χρησιμοποιουν το εν λογω ενζυμο και μεθοδοι για παραγωγη και καθαρισμο του εν λογω ενζυμου
AU2002325782A1 (en) Pharmaceutical composition and method of treatment of human malignancies with arginine deprivation
AR030735A1 (es) Un procedimiento para la produccion de un extracto de champinon natural
TW200407133A (en) Novel PPARα and PPARγ agonists
Emami et al. Histamine and VIP interactions with receptor-cyclic AMP systems in the human gastric cancer cell line HGT-1
DE60226896D1 (de) Herstellung von f(ab')2 fragmenten in saügetierzelle
WO2003052084A3 (fr) Construits cellulaires cultives in vitro, preparation et utilisations
AU2003271811A1 (en) Novel derivatives of 4,4'-dithiobis-(3-aminobutane-1-sulphonates) and compositions containing same
RS88704A (en) Acyl-3-carboxyphenylurea derivatives, method for production and use thereof
AU2003288867A1 (en) A moist snuff composition comprising at least one thickening agent and a method for its manufacture
NZ515531A (en) Substituted 3-pyridyl-4-arylpyrroles, and related therapeutic and prophylactic methods
DE60327710D1 (de) Modifizierte zytokine für krebs therapie