ZA200507153B - Improved alphavirus replicons and helper construtcs - Google Patents
Improved alphavirus replicons and helper construtcs Download PDFInfo
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- ZA200507153B ZA200507153B ZA200507153A ZA200507153A ZA200507153B ZA 200507153 B ZA200507153 B ZA 200507153B ZA 200507153 A ZA200507153 A ZA 200507153A ZA 200507153 A ZA200507153 A ZA 200507153A ZA 200507153 B ZA200507153 B ZA 200507153B
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| DE10049587A1 (de) | 2000-10-06 | 2002-05-02 | Icon Genetics Ag | Vektorsystem für Pflanzen |
| JP4790984B2 (ja) | 2001-09-06 | 2011-10-12 | アルファヴァックス，インコーポレイテッド | アルファウイルスレプリコンベクター系 |
| BR122019005271B1 (pt) | 2002-12-13 | 2020-10-13 | Alphavax, Inc. | método para a preparação de partículas de replicon de alfavírus (arps) |
| CA2509973C (en) | 2002-12-13 | 2013-02-26 | Alphavax, Inc. | Multi-antigenic alphavirus replicon particles and methods |
| AU2004257214B2 (en) | 2003-07-11 | 2010-04-22 | Alphavax, Inc. | Alphavirus-based cytomegalovirus vaccines |
| PT1751289E (pt) | 2004-05-18 | 2009-03-31 | Alphavax Inc | Vectores de alfavirais derivados da tc-83, partículas e métodos |
| EP2811027A1 (de) | 2004-05-21 | 2014-12-10 | Novartis Vaccines and Diagnostics, Inc. | Alphavirus-Vektoren für RSV- und PIV-Impfstoffe |
| AU2005327198B2 (en) * | 2004-07-09 | 2011-03-31 | University Of North Carolina At Chapel Hill | Viral adjuvants |
| AU2006302794B2 (en) * | 2005-02-15 | 2011-08-04 | Children's Hospital, Inc. | New live virus vaccines |
| AU2007342333B2 (en) | 2006-09-12 | 2013-02-28 | Alphavax, Inc. | Alphavirus replicon particles encoding IL- 12 as immunological adjuvants |
| EP2061508B1 (de) | 2006-09-12 | 2014-10-15 | Alphavax, Inc. | An protein-antigene angepasste alphavirus replikons als immunologisches adjuvant |
| WO2008058035A1 (en) | 2006-11-03 | 2008-05-15 | Alphavax, Inc. | Alphavirus and alphavirus replicon particle formulations and methods |
| AU2008266807B2 (en) | 2007-06-21 | 2012-08-16 | Alphavax, Inc. | Promoterless cassettes for expression of alphavirus structural proteins |
| WO2009089040A1 (en) * | 2008-01-11 | 2009-07-16 | Jaffrey Samie R | Methods for expressing proteins in axons |
| AU2014265084B2 (en) * | 2008-01-24 | 2016-09-29 | The Board Of Regents Of The University Of Texas System | Attentuated recombinant alphaviruses incapable of replicating in mosquitoes and uses thereof |
| JP5758632B2 (ja) * | 2008-01-24 | 2015-08-05 | ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システムＴｈｅ Ｂｏａｒｄ Ｏｆ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｔｅｘａｓ Ｓｙｓｔｅｍ | 蚊において複製不可能な弱毒化組み換えアルファウイルス属及びそれらの使用 |
| AU2016228199B2 (en) * | 2008-01-24 | 2018-06-14 | The Board Of Regents Of The University Of Texas System | Attentuated recombinant alphaviruses incapable of replicating in mosquitoes and uses thereof |
| EP2331557B1 (de) * | 2008-08-15 | 2013-12-18 | Novartis AG | Alphavirusverpackungszellinien |
| WO2010039649A2 (en) * | 2008-10-03 | 2010-04-08 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Flavivirus-based system for production of hepatitis c virus (hcv) |
| ES2525707T3 (es) | 2008-12-01 | 2014-12-29 | Alphavax, Inc. | Uso de microRNAs para el control de ácidos nucleicos colaboradores de virus |
| AU2010234362B2 (en) | 2009-04-08 | 2015-11-26 | Alphavax, Inc. | Alphavirus replicon particles expressing TRP2 |
| WO2012001196A2 (es) * | 2010-06-28 | 2012-01-05 | Proyecto De Biomedicina Cima, S.L. | Vectores alfavirales y usos de los mismos para la expresión de genes heterólogos |
| HUE047796T2 (hu) | 2010-07-06 | 2020-05-28 | Glaxosmithkline Biologicals Sa | RNS bevitele több immunútvonal bekapcsolására |
| WO2012006378A1 (en) | 2010-07-06 | 2012-01-12 | Novartis Ag | Liposomes with lipids having an advantageous pka- value for rna delivery |
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| PT4066856T (pt) | 2010-08-31 | 2023-01-02 | Glaxosmithkline Biologicals Sa | Lipossomas peguilados para entrega de arn codificador de imunogénio |
| CN103269713B (zh) | 2010-10-11 | 2016-01-20 | 诺华有限公司 | 抗原递送平台 |
| US8892184B2 (en) | 2010-10-18 | 2014-11-18 | Siemens Medical Solutions Usa, Inc. | Systems and methods for reducing interference in a dual modality imaging system |
| EP2633049B1 (de) | 2010-10-27 | 2018-10-10 | Harrisvaccines Inc | Verfahren und zusammensetzungen zum schutz von wirbellosen wassertieren gegen krankheiten |
| US10004797B2 (en) | 2010-10-27 | 2018-06-26 | Harrisvaccines, Inc. | Method of rapidly producing improved vaccines for animals |
| US8822427B2 (en) | 2010-10-27 | 2014-09-02 | Harrisvaccines | Methods and compositions to protect aquatic invertebrates from disease |
| CN102816781B (zh) * | 2011-06-10 | 2016-01-20 | 中国疾病预防控制中心病毒病预防控制所 | 一种辛德毕斯病毒xj-160缺陷型复制子及其构建方法和应用 |
| JP2014522842A (ja) * | 2011-07-06 | 2014-09-08 | ノバルティス アーゲー | 免疫原性組み合わせ組成物およびその使用 |
| WO2013066665A1 (en) | 2011-10-19 | 2013-05-10 | Harrisvaccines, Inc | Method of rapidly producing improved vaccines for animals |
| SG11201403445YA (en) * | 2011-12-22 | 2014-07-30 | Hoffmann La Roche | Full length antibody display system for eukaryotic cells and its use |
| WO2013177133A2 (en) | 2012-05-21 | 2013-11-28 | The Regents Of The Univerisity Of California | Generation of human ips cells by a synthetic self- replicative rna |
| EP2943221A1 (de) * | 2013-01-10 | 2015-11-18 | Novartis AG | Immunogene influenzaviruszusammensetzungen und verwendungen davon |
| US9637532B2 (en) | 2013-07-12 | 2017-05-02 | Vlp Therapeutics, Llc | Virus like particle comprising PD-1 antigen or PD-1 ligand antigen |
| EP3103807B1 (de) * | 2014-02-06 | 2021-08-25 | Japan Science And Technology Agency | Peptid/beta-1,3-glucankomplex und herstellungsverfahren dafür sowie pharmazeutische zusammensetzung mit dem peptid/beta-1,3-glucankomplex |
| EP3127898B1 (de) | 2014-04-04 | 2021-08-25 | Adeka Corporation | Oximesterverbindung und fotopolymerisationsinitiator mit der verbindung |
| CA3005739A1 (en) | 2015-11-18 | 2017-05-26 | Orbis Health Solutions Llc | T7 alpha viral vector system |
| WO2017162266A1 (en) | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Rna replicon for versatile and efficient gene expression |
| WO2017162265A1 (en) * | 2016-03-21 | 2017-09-28 | Biontech Rna Pharmaceuticals Gmbh | Trans-replicating rna |
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| ES2453344T3 (es) | 2014-04-07 |
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| BRPI0408424B1 (pt) | 2020-12-01 |
| CA2518546A1 (en) | 2004-10-07 |
| CA2518546C (en) | 2012-11-13 |
| NZ542353A (en) | 2008-07-31 |
| KR20060006780A (ko) | 2006-01-19 |
| PL1608762T3 (pl) | 2014-06-30 |
| BRPI0408424B8 (pt) | 2021-05-25 |
| JP5016305B2 (ja) | 2012-09-05 |
| JP5572144B2 (ja) | 2014-08-13 |
| HK1084692A1 (en) | 2006-08-04 |
| WO2004085660A3 (en) | 2004-12-09 |
| JP2012050450A (ja) | 2012-03-15 |
| JP2006520602A (ja) | 2006-09-14 |
| KR101518309B1 (ko) | 2015-05-08 |
| IL170607A (en) | 2011-09-27 |
| CN1791678A (zh) | 2006-06-21 |
| EP1608762B1 (de) | 2014-01-08 |
| MXPA05010007A (es) | 2006-03-10 |
| WO2004085660A2 (en) | 2004-10-07 |
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