ZA200504163B - Methods for selectively inhibiting janus tyrosine kinase 3 (Jak3) - Google Patents
Methods for selectively inhibiting janus tyrosine kinase 3 (Jak3) Download PDFInfo
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- ZA200504163B ZA200504163B ZA200504163A ZA200504163A ZA200504163B ZA 200504163 B ZA200504163 B ZA 200504163B ZA 200504163 A ZA200504163 A ZA 200504163A ZA 200504163 A ZA200504163 A ZA 200504163A ZA 200504163 B ZA200504163 B ZA 200504163B
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
- G01N2333/91215—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases with a definite EC number (2.7.1.-)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43185102P | 2002-12-09 | 2002-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200504163B true ZA200504163B (en) | 2007-03-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| ZA200504163A ZA200504163B (en) | 2002-12-09 | 2005-05-23 | Methods for selectively inhibiting janus tyrosine kinase 3 (Jak3) |
Country Status (17)
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| US (2) | US7365096B2 (https=) |
| EP (1) | EP1578411A4 (https=) |
| JP (1) | JP2006514021A (https=) |
| KR (1) | KR20050084224A (https=) |
| CN (1) | CN1747729A (https=) |
| AU (1) | AU2003297740B2 (https=) |
| BR (1) | BR0317099A (https=) |
| CA (1) | CA2506432A1 (https=) |
| EC (1) | ECSP055843A (https=) |
| HU (1) | HUP0500844A2 (https=) |
| MX (1) | MXPA05006133A (https=) |
| NO (1) | NO20052497L (https=) |
| NZ (1) | NZ540427A (https=) |
| PL (1) | PL376844A1 (https=) |
| RU (1) | RU2005121672A (https=) |
| WO (1) | WO2004052359A1 (https=) |
| ZA (1) | ZA200504163B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| JP4928937B2 (ja) | 2003-03-28 | 2012-05-09 | スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ | ミグラスタチンアナログおよびその使用 |
| BRPI0413018B8 (pt) | 2003-07-30 | 2021-05-25 | Rigel Pharmaceuticals Inc | composto, e, uso de um composto |
| AU2005237254B2 (en) * | 2004-05-03 | 2010-02-04 | Novartis Ag | Combinations comprising a S1P receptor agonist and a JAK3 kinase inhibitor |
| WO2006001967A2 (en) | 2004-05-25 | 2006-01-05 | Sloan-Kettering Institute For Cancer Research | Migrastatin analogs in the treatment of cancer |
| US8188141B2 (en) | 2004-09-23 | 2012-05-29 | Sloan-Kettering Institute For Cancer Research | Isomigrastatin analogs in the treatment of cancer |
| GB0507918D0 (en) | 2005-04-19 | 2005-05-25 | Novartis Ag | Organic compounds |
| EP1883302A4 (en) * | 2005-05-03 | 2009-05-20 | Rigel Pharmaceuticals Inc | JAK KINASE HEMMER AND ITS USE |
| TR201802449T4 (tr) | 2005-10-26 | 2018-03-21 | Novartis Ag | Ailesel akdeniz hummasının anti ıl-1beta antikorları ile tedavisi. |
| RU2487711C2 (ru) | 2005-11-21 | 2013-07-20 | Новартис Аг | Лечение нейроэндокринных опухолей |
| GB0601744D0 (en) | 2006-01-27 | 2006-03-08 | Novartis Ag | Organic compounds |
| EP2468301A1 (en) | 2007-05-29 | 2012-06-27 | Novartis AG | New indications for anti-IL-1-beta therapy |
| WO2009060035A1 (en) | 2007-11-08 | 2009-05-14 | Novartis Ag | Gene expression signatures for chronic/sclerosing allograft nephropathy |
| US8268834B2 (en) | 2008-03-19 | 2012-09-18 | Novartis Ag | Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme |
| CA2767616A1 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| US8791100B2 (en) | 2010-02-02 | 2014-07-29 | Novartis Ag | Aryl benzylamine compounds |
| UA112517C2 (uk) | 2010-07-06 | 2016-09-26 | Новартіс Аг | Тетрагідропіридопіримідинові похідні |
| US9018006B2 (en) | 2010-07-23 | 2015-04-28 | The University Of Toledo | Stable Tregs and related materials and methods |
| JP2014518256A (ja) | 2011-06-27 | 2014-07-28 | ノバルティス アーゲー | テトラヒドロ−ピリド−ピリミジン誘導体の固体形態および塩類 |
| KR20140058543A (ko) | 2011-07-08 | 2014-05-14 | 노파르티스 아게 | 신규 피롤로 피리미딘 유도체 |
| WO2013057711A1 (en) | 2011-10-21 | 2013-04-25 | Novartis Ag | Quinazoline derivatives as pi3k modulators |
| US20140348848A1 (en) | 2011-12-02 | 2014-11-27 | Dhananjay Kaul | Anti-il-1beta (interleukin-1beta) antibody-based prophylactic therapy to prevent complications leading to vaso-occlusion in sickle cell disease |
| DK2790705T3 (en) | 2011-12-15 | 2018-03-12 | Novartis Ag | Use of inhibitors of the activity or function of PI3K |
| WO2013093850A1 (en) | 2011-12-22 | 2013-06-27 | Novartis Ag | Quinoline derivatives |
| JP5903499B2 (ja) | 2011-12-22 | 2016-04-13 | ノバルティス アーゲー | ジヒドロ−ベンゾ−オキサジンおよびジヒドロ−ピリド−オキサジン誘導体 |
| US9371265B2 (en) * | 2012-03-26 | 2016-06-21 | Ep Pharma, Inc. | Compositions and methods related to inhibitors of JAK kinase |
| TW201422625A (zh) | 2012-11-26 | 2014-06-16 | Novartis Ag | 二氫－吡啶并－□衍生物之固體形式 |
| WO2014128612A1 (en) | 2013-02-20 | 2014-08-28 | Novartis Ag | Quinazolin-4-one derivatives |
| UY35675A (es) | 2013-07-24 | 2015-02-27 | Novartis Ag | Derivados sustituidos de quinazolin-4-ona |
| US9657007B2 (en) | 2013-09-22 | 2017-05-23 | Calitor Sciences, Llc | Substituted aminopyrimidine compounds and methods of use |
| US9512084B2 (en) | 2013-11-29 | 2016-12-06 | Novartis Ag | Amino pyrimidine derivatives |
| KR20160141856A (ko) | 2014-04-24 | 2016-12-09 | 노파르티스 아게 | 포스파티딜이노시톨 3-키나제 억제제로서의 피라진 유도체 |
| KR20160145780A (ko) | 2014-04-24 | 2016-12-20 | 노파르티스 아게 | 포스파티딜이노시톨 3-키나제 억제제로서의 아미노 피리딘 유도체 |
| EP3134397A1 (en) | 2014-04-24 | 2017-03-01 | Novartis AG | Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| EP3146077A4 (en) | 2014-05-22 | 2018-05-02 | The Scripps Research Institute | Tissue molecular signatures of kidney transplant rejections |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| CN104090115B (zh) * | 2014-07-10 | 2016-01-13 | 上海益诺思生物技术有限公司 | 次级t细胞依赖抗体反应检测外源性化合物免疫抑制方法 |
| AU2019209960B2 (en) | 2018-01-20 | 2023-11-23 | Sunshine Lake Pharma Co., Ltd. | Substituted aminopyrimidine compounds and methods of use |
| WO2020067887A1 (en) | 2018-09-24 | 2020-04-02 | Erasmus University Medical Center Rotterdam | Specific inhibition of janus kinase 3 (jak3) for modulating anti-tumor immune responses |
| BR112021023054A2 (pt) | 2019-05-23 | 2022-03-29 | Novartis Ag | Formas cristalinas de um inibidor de btk |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA712187A (en) * | 1965-06-22 | J. C. Buisson Paul | 2-(2'-oxo-1'-cyclododecyl) acetic acid, the salts thereof, and process of preparing same | |
| FR1466205A (fr) * | 1960-04-01 | 1967-01-20 | Chimie Atomistique | Acide 1-cétocyclododécyl-2-acétique, ses sels et leur procédé de préparation |
| AU566673B2 (en) | 1983-09-15 | 1987-10-29 | F. Hoffmann-La Roche Ag | Phenethylamine derivatives |
| US6136595A (en) * | 1993-07-29 | 2000-10-24 | St. Jude Children's Research Hospital | Jak kinases and regulations of cytokine signal transduction |
| US6313129B1 (en) | 1998-08-21 | 2001-11-06 | Hughes Institute | Therapeutic compounds |
| US6080747A (en) * | 1999-03-05 | 2000-06-27 | Hughes Institute | JAK-3 inhibitors for treating allergic disorders |
| JP2003518023A (ja) * | 1999-11-30 | 2003-06-03 | パーカー ヒューズ インスティテュート | トロンビン誘導血小板凝集の阻害剤 |
| MY128450A (en) | 2000-05-24 | 2007-02-28 | Upjohn Co | 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives |
| CA2326952A1 (en) | 2000-11-27 | 2002-05-27 | The Hospital For Sick Children | T cell protein tyrosine phosphatase |
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- 2003-12-09 CA CA002506432A patent/CA2506432A1/en not_active Abandoned
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- 2003-12-09 MX MXPA05006133A patent/MXPA05006133A/es unknown
- 2003-12-09 HU HU0500844A patent/HUP0500844A2/hu unknown
- 2003-12-09 NZ NZ540427A patent/NZ540427A/en unknown
- 2003-12-09 RU RU2005121672/15A patent/RU2005121672A/ru not_active Application Discontinuation
- 2003-12-09 AU AU2003297740A patent/AU2003297740B2/en not_active Ceased
- 2003-12-09 PL PL376844A patent/PL376844A1/pl not_active Application Discontinuation
- 2003-12-09 US US10/731,769 patent/US7365096B2/en not_active Expired - Fee Related
- 2003-12-09 CN CNA2003801054687A patent/CN1747729A/zh active Pending
- 2003-12-09 EP EP03796805A patent/EP1578411A4/en not_active Withdrawn
- 2003-12-09 KR KR1020057010469A patent/KR20050084224A/ko not_active Ceased
- 2003-12-09 BR BR0317099-3A patent/BR0317099A/pt not_active IP Right Cessation
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2005
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- 2005-05-24 NO NO20052497A patent/NO20052497L/no not_active Application Discontinuation
- 2005-06-08 EC EC2005005843A patent/ECSP055843A/es unknown
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2007
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2003297740A1 (en) | 2004-06-30 |
| NO20052497L (no) | 2005-09-02 |
| ECSP055843A (es) | 2005-11-22 |
| US20050203177A1 (en) | 2005-09-15 |
| KR20050084224A (ko) | 2005-08-26 |
| US7365096B2 (en) | 2008-04-29 |
| MXPA05006133A (es) | 2006-03-09 |
| US20080167220A1 (en) | 2008-07-10 |
| CN1747729A (zh) | 2006-03-15 |
| EP1578411A4 (en) | 2007-05-02 |
| CA2506432A1 (en) | 2004-06-24 |
| RU2005121672A (ru) | 2005-11-20 |
| WO2004052359A1 (en) | 2004-06-24 |
| US7928062B2 (en) | 2011-04-19 |
| AU2003297740B2 (en) | 2008-09-11 |
| HUP0500844A2 (en) | 2007-08-28 |
| NO20052497D0 (no) | 2005-05-24 |
| JP2006514021A (ja) | 2006-04-27 |
| BR0317099A (pt) | 2005-10-25 |
| AU2003297740A2 (en) | 2004-06-30 |
| EP1578411A1 (en) | 2005-09-28 |
| NZ540427A (en) | 2008-04-30 |
| PL376844A1 (pl) | 2006-01-09 |
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