ZA200500167B - Benzamide or phenylacetamide derivatives useful as thyroid receptor ligands - Google Patents
Benzamide or phenylacetamide derivatives useful as thyroid receptor ligands Download PDFInfo
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- ZA200500167B ZA200500167B ZA200500167A ZA200500167A ZA200500167B ZA 200500167 B ZA200500167 B ZA 200500167B ZA 200500167 A ZA200500167 A ZA 200500167A ZA 200500167 A ZA200500167 A ZA 200500167A ZA 200500167 B ZA200500167 B ZA 200500167B
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- IAIDUHCBNLFXEF-MNEFBYGVSA-N zofenopril Chemical compound C([C@@H](C)C(=O)N1[C@@H](C[C@@H](C1)SC=1C=CC=CC=1)C(O)=O)SC(=O)C1=CC=CC=C1 IAIDUHCBNLFXEF-MNEFBYGVSA-N 0.000 description 1
- 229960002769 zofenopril Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0215978.8A GB0215978D0 (en) | 2002-07-10 | 2002-07-10 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200500167B true ZA200500167B (en) | 2006-07-26 |
Family
ID=9940187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200500167A ZA200500167B (en) | 2002-07-10 | 2005-01-07 | Benzamide or phenylacetamide derivatives useful as thyroid receptor ligands |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7153997B2 (de) |
| EP (2) | EP1537073B1 (de) |
| JP (1) | JP2005538076A (de) |
| KR (1) | KR20050053590A (de) |
| CN (1) | CN100347152C (de) |
| AT (1) | ATE372980T1 (de) |
| AU (1) | AU2003250908A1 (de) |
| BR (1) | BR0312655A (de) |
| CA (1) | CA2492046A1 (de) |
| DE (1) | DE60316312T2 (de) |
| GB (1) | GB0215978D0 (de) |
| HR (1) | HRP20050015A2 (de) |
| IS (1) | IS7649A (de) |
| MX (1) | MXPA05000460A (de) |
| NO (1) | NO20050714L (de) |
| PL (1) | PL374733A1 (de) |
| RS (1) | RS20050017A (de) |
| RU (1) | RU2317287C2 (de) |
| WO (1) | WO2004007430A2 (de) |
| ZA (1) | ZA200500167B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20110713A1 (it) * | 2011-04-29 | 2012-10-30 | Bracco Imaging Spa | Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina |
| WO2005051298A2 (en) | 2003-11-19 | 2005-06-09 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
| WO2005085865A2 (en) * | 2004-03-09 | 2005-09-15 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with thyroid hormone receptor beta (thrb) |
| GB0406380D0 (en) * | 2004-03-22 | 2004-04-21 | Karobio Ab | Novel pharmaceutical compositions |
| GB0406378D0 (en) * | 2004-03-22 | 2004-04-21 | Karobio Ab | Novel pharmaceutical compositions |
| US20090232879A1 (en) | 2005-05-26 | 2009-09-17 | Metabasis Therapeutics, Inc. | Thyromimetics for the Treatment of Fatty Liver Diseases |
| GB0606212D0 (en) * | 2006-03-28 | 2006-05-10 | Karobio Ab | Pharmaceutical compositions |
| CN102203130B (zh) * | 2010-08-06 | 2014-06-25 | 贝达药业股份有限公司 | Glp-1衍生物及其应用 |
| CA2809958A1 (en) | 2010-08-31 | 2012-03-08 | Snu R & Db Foundation | Use of the fetal reprogramming of a ppar ? agonist |
| CN103534232A (zh) * | 2011-04-08 | 2014-01-22 | 伯拉考成像股份公司 | 用于制备3,5-二碘-o-[3-碘苯基]-l-酪氨酸的硫酸化衍生物的方法 |
| KR20190104524A (ko) | 2016-11-21 | 2019-09-10 | 바이킹 테라퓨틱스 인코포레이티드 | 당원축적질환의 치료 방법 |
| EP3634426A4 (de) | 2017-06-05 | 2021-04-07 | Viking Therapeutics, Inc. | Zusammensetzungen zur behandlung von fibrose |
| EA202091979A1 (ru) | 2018-03-22 | 2021-06-22 | Вайкинг Терапьютикс, Инк. | Кристаллические формы и способы получения кристаллических форм соединения |
| US12102646B2 (en) | 2018-12-05 | 2024-10-01 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis and inflammation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2108855T3 (es) * | 1992-07-21 | 1998-01-01 | Ciba Geigy Ag | Derivados de acido oxamico como agentes hipocolesteremicos. |
| GB9816935D0 (en) * | 1998-08-05 | 1998-09-30 | Karobio Ab | Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders |
| GB9828442D0 (en) | 1998-12-24 | 1999-02-17 | Karobio Ab | Novel thyroid receptor ligands and method II |
| US6395784B1 (en) | 2000-06-07 | 2002-05-28 | Bristol-Myers Squibb Company | Benzamide ligands for the thyroid receptor |
| JP4225791B2 (ja) * | 2001-05-18 | 2009-02-18 | キッセイ薬品工業株式会社 | 肝癌の予防または再発抑制剤 |
-
2002
- 2002-07-10 GB GBGB0215978.8A patent/GB0215978D0/en not_active Ceased
-
2003
- 2003-07-08 US US10/520,902 patent/US7153997B2/en not_active Expired - Fee Related
- 2003-07-08 AU AU2003250908A patent/AU2003250908A1/en not_active Abandoned
- 2003-07-08 KR KR1020057000466A patent/KR20050053590A/ko not_active Application Discontinuation
- 2003-07-08 WO PCT/EP2003/007333 patent/WO2004007430A2/en active IP Right Grant
- 2003-07-08 MX MXPA05000460A patent/MXPA05000460A/es not_active Application Discontinuation
- 2003-07-08 EP EP03763744A patent/EP1537073B1/de not_active Expired - Lifetime
- 2003-07-08 AT AT03763744T patent/ATE372980T1/de not_active IP Right Cessation
- 2003-07-08 BR BR0312655-2A patent/BR0312655A/pt not_active IP Right Cessation
- 2003-07-08 CA CA002492046A patent/CA2492046A1/en not_active Abandoned
- 2003-07-08 DE DE60316312T patent/DE60316312T2/de not_active Expired - Fee Related
- 2003-07-08 EP EP07017641A patent/EP1862450A2/de not_active Withdrawn
- 2003-07-08 CN CNB038163055A patent/CN100347152C/zh not_active Expired - Fee Related
- 2003-07-08 RU RU2005103406/04A patent/RU2317287C2/ru not_active IP Right Cessation
- 2003-07-08 RS YUP-2005/0017A patent/RS20050017A/sr unknown
- 2003-07-08 PL PL03374733A patent/PL374733A1/xx not_active IP Right Cessation
- 2003-07-08 JP JP2004520522A patent/JP2005538076A/ja active Pending
-
2005
- 2005-01-07 ZA ZA200500167A patent/ZA200500167B/en unknown
- 2005-01-10 HR HR20050015A patent/HRP20050015A2/hr not_active Application Discontinuation
- 2005-01-14 IS IS7649A patent/IS7649A/is unknown
- 2005-02-10 NO NO20050714A patent/NO20050714L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005538076A (ja) | 2005-12-15 |
| RS20050017A (en) | 2007-08-03 |
| US20060135614A1 (en) | 2006-06-22 |
| AU2003250908A1 (en) | 2004-02-02 |
| BR0312655A (pt) | 2005-05-24 |
| GB0215978D0 (en) | 2002-08-21 |
| EP1862450A2 (de) | 2007-12-05 |
| HRP20050015A2 (en) | 2005-08-31 |
| CN1668579A (zh) | 2005-09-14 |
| MXPA05000460A (es) | 2005-07-22 |
| ATE372980T1 (de) | 2007-09-15 |
| IS7649A (is) | 2005-01-14 |
| PL374733A1 (en) | 2005-10-31 |
| NO20050714L (no) | 2005-02-10 |
| DE60316312T2 (de) | 2008-06-05 |
| DE60316312D1 (de) | 2007-10-25 |
| CA2492046A1 (en) | 2004-01-22 |
| WO2004007430A3 (en) | 2004-02-19 |
| US7153997B2 (en) | 2006-12-26 |
| RU2005103406A (ru) | 2005-06-27 |
| CN100347152C (zh) | 2007-11-07 |
| EP1537073A2 (de) | 2005-06-08 |
| EP1537073B1 (de) | 2007-09-12 |
| KR20050053590A (ko) | 2005-06-08 |
| WO2004007430A2 (en) | 2004-01-22 |
| RU2317287C2 (ru) | 2008-02-20 |
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