RS20050017A - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- RS20050017A RS20050017A YUP-2005/0017A YUP20050017A RS20050017A RS 20050017 A RS20050017 A RS 20050017A YU P20050017 A YUP20050017 A YU P20050017A RS 20050017 A RS20050017 A RS 20050017A
- Authority
- RS
- Serbia
- Prior art keywords
- novel compounds
- compounds
- inhibiting
- administered
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Ovaj pronalazak odnosi se na nova jedinjenja koja predstavljaju ligande tireoidnih receptora, i na postupke za dobijanje tih jedinjenja i postupke za korišćenje tih jedinjenja u regulaciji metabolizma. Osim toga, postupak se odnosi na prevenciju, inhibiranje ili lečenje oboljenja ili poremećaja povezanih sa disfunkcijom metabolizma ili onih koji zavise od ekspresije T3 regulisanog gena, gde se ovde opisano jedinjenje daje u terapeutski efikasnim količinama.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0215978.8A GB0215978D0 (en) | 2002-07-10 | 2002-07-10 | Novel compounds |
PCT/EP2003/007333 WO2004007430A2 (en) | 2002-07-10 | 2003-07-08 | Benzamide or phenylacetamide derivatives useful as thyroid receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
RS20050017A true RS20050017A (en) | 2007-08-03 |
Family
ID=9940187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YUP-2005/0017A RS20050017A (en) | 2002-07-10 | 2003-07-08 | Novel compounds |
Country Status (20)
Country | Link |
---|---|
US (1) | US7153997B2 (sr) |
EP (2) | EP1862450A2 (sr) |
JP (1) | JP2005538076A (sr) |
KR (1) | KR20050053590A (sr) |
CN (1) | CN100347152C (sr) |
AT (1) | ATE372980T1 (sr) |
AU (1) | AU2003250908A1 (sr) |
BR (1) | BR0312655A (sr) |
CA (1) | CA2492046A1 (sr) |
DE (1) | DE60316312T2 (sr) |
GB (1) | GB0215978D0 (sr) |
HR (1) | HRP20050015A2 (sr) |
IS (1) | IS7649A (sr) |
MX (1) | MXPA05000460A (sr) |
NO (1) | NO20050714L (sr) |
PL (1) | PL374733A1 (sr) |
RS (1) | RS20050017A (sr) |
RU (1) | RU2317287C2 (sr) |
WO (1) | WO2004007430A2 (sr) |
ZA (1) | ZA200500167B (sr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20110713A1 (it) * | 2011-04-29 | 2012-10-30 | Bracco Imaging Spa | Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina |
US7829552B2 (en) | 2003-11-19 | 2010-11-09 | Metabasis Therapeutics, Inc. | Phosphorus-containing thyromimetics |
WO2005085865A2 (en) * | 2004-03-09 | 2005-09-15 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with thyroid hormone receptor beta (thrb) |
GB0406378D0 (en) * | 2004-03-22 | 2004-04-21 | Karobio Ab | Novel pharmaceutical compositions |
GB0406380D0 (en) * | 2004-03-22 | 2004-04-21 | Karobio Ab | Novel pharmaceutical compositions |
MX2007014502A (es) | 2005-05-26 | 2008-02-07 | Metabasis Therapeutics Inc | Tiromimeticos para el tratamiento de enfermedades del higado graso. |
GB0606212D0 (en) * | 2006-03-28 | 2006-05-10 | Karobio Ab | Pharmaceutical compositions |
CN102203130B (zh) * | 2010-08-06 | 2014-06-25 | 贝达药业股份有限公司 | Glp-1衍生物及其应用 |
JP2013538215A (ja) | 2010-08-31 | 2013-10-10 | エスエヌユー アールアンドディービー ファウンデーション | PPARδアゴニストの胎児再プログラミング用途 |
SI2694471T1 (sl) * | 2011-04-08 | 2017-12-29 | Bracco Imaging S.P.A. | Postopek priprave sulfatiranega derivata 3,5-dijodo-O-(3-jodofenil)-L-tirozina |
EP3541395A4 (en) | 2016-11-21 | 2020-07-01 | Viking Therapeutics, Inc. | GLYCOGENOSIS TREATMENT METHODS |
US11707472B2 (en) | 2017-06-05 | 2023-07-25 | Viking Therapeutics, Inc. | Compositions for the treatment of fibrosis |
CN112135832A (zh) | 2018-03-22 | 2020-12-25 | 维京治疗公司 | 化合物的晶型和制备化合物的晶型的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE159515T1 (de) * | 1992-07-21 | 1997-11-15 | Ciba Geigy Ag | Oxamidsäure-derivate als hypocholesterämische mittel |
GB9816935D0 (en) * | 1998-08-05 | 1998-09-30 | Karobio Ab | Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders |
GB9828442D0 (en) * | 1998-12-24 | 1999-02-17 | Karobio Ab | Novel thyroid receptor ligands and method II |
US6395784B1 (en) * | 2000-06-07 | 2002-05-28 | Bristol-Myers Squibb Company | Benzamide ligands for the thyroid receptor |
WO2002094319A1 (en) | 2001-05-18 | 2002-11-28 | Kissei Pharmaceutical Co., Ltd. | Preventive or recurrence-suppressive agents for liver cancer |
-
2002
- 2002-07-10 GB GBGB0215978.8A patent/GB0215978D0/en not_active Ceased
-
2003
- 2003-07-08 KR KR1020057000466A patent/KR20050053590A/ko not_active Application Discontinuation
- 2003-07-08 EP EP07017641A patent/EP1862450A2/en not_active Withdrawn
- 2003-07-08 RU RU2005103406/04A patent/RU2317287C2/ru not_active IP Right Cessation
- 2003-07-08 AT AT03763744T patent/ATE372980T1/de not_active IP Right Cessation
- 2003-07-08 BR BR0312655-2A patent/BR0312655A/pt not_active IP Right Cessation
- 2003-07-08 WO PCT/EP2003/007333 patent/WO2004007430A2/en active IP Right Grant
- 2003-07-08 AU AU2003250908A patent/AU2003250908A1/en not_active Abandoned
- 2003-07-08 DE DE60316312T patent/DE60316312T2/de not_active Expired - Fee Related
- 2003-07-08 RS YUP-2005/0017A patent/RS20050017A/sr unknown
- 2003-07-08 CN CNB038163055A patent/CN100347152C/zh not_active Expired - Fee Related
- 2003-07-08 PL PL03374733A patent/PL374733A1/xx not_active IP Right Cessation
- 2003-07-08 JP JP2004520522A patent/JP2005538076A/ja active Pending
- 2003-07-08 MX MXPA05000460A patent/MXPA05000460A/es not_active Application Discontinuation
- 2003-07-08 US US10/520,902 patent/US7153997B2/en not_active Expired - Fee Related
- 2003-07-08 CA CA002492046A patent/CA2492046A1/en not_active Abandoned
- 2003-07-08 EP EP03763744A patent/EP1537073B1/en not_active Expired - Lifetime
-
2005
- 2005-01-07 ZA ZA200500167A patent/ZA200500167B/en unknown
- 2005-01-10 HR HR20050015A patent/HRP20050015A2/hr not_active Application Discontinuation
- 2005-01-14 IS IS7649A patent/IS7649A/is unknown
- 2005-02-10 NO NO20050714A patent/NO20050714L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN100347152C (zh) | 2007-11-07 |
WO2004007430A3 (en) | 2004-02-19 |
WO2004007430A2 (en) | 2004-01-22 |
NO20050714L (no) | 2005-02-10 |
US20060135614A1 (en) | 2006-06-22 |
PL374733A1 (en) | 2005-10-31 |
RU2317287C2 (ru) | 2008-02-20 |
HRP20050015A2 (en) | 2005-08-31 |
DE60316312T2 (de) | 2008-06-05 |
JP2005538076A (ja) | 2005-12-15 |
US7153997B2 (en) | 2006-12-26 |
CA2492046A1 (en) | 2004-01-22 |
AU2003250908A1 (en) | 2004-02-02 |
EP1537073B1 (en) | 2007-09-12 |
CN1668579A (zh) | 2005-09-14 |
ZA200500167B (en) | 2006-07-26 |
MXPA05000460A (es) | 2005-07-22 |
BR0312655A (pt) | 2005-05-24 |
KR20050053590A (ko) | 2005-06-08 |
EP1537073A2 (en) | 2005-06-08 |
DE60316312D1 (de) | 2007-10-25 |
EP1862450A2 (en) | 2007-12-05 |
ATE372980T1 (de) | 2007-09-15 |
GB0215978D0 (en) | 2002-08-21 |
IS7649A (is) | 2005-01-14 |
RU2005103406A (ru) | 2005-06-27 |
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