ZA200409582B - Use of CETP inhibitors and optionally HMG Coa reductable inhibitors and/or antihypertensive agents - Google Patents
Use of CETP inhibitors and optionally HMG Coa reductable inhibitors and/or antihypertensive agents Download PDFInfo
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- ZA200409582B ZA200409582B ZA200409582A ZA200409582A ZA200409582B ZA 200409582 B ZA200409582 B ZA 200409582B ZA 200409582 A ZA200409582 A ZA 200409582A ZA 200409582 A ZA200409582 A ZA 200409582A ZA 200409582 B ZA200409582 B ZA 200409582B
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- disease
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- optionally
- optionally mono
- pharmaceutically acceptable
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Pain & Pain Management (AREA)
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- Physical Education & Sports Medicine (AREA)
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- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39339502P | 2002-07-02 | 2002-07-02 |
Publications (1)
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| ZA200409582B true ZA200409582B (en) | 2006-08-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200409582A ZA200409582B (en) | 2002-07-02 | 2004-11-26 | Use of CETP inhibitors and optionally HMG Coa reductable inhibitors and/or antihypertensive agents |
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| US (1) | US20040053842A1 (pt) |
| EP (1) | EP1519754A1 (pt) |
| JP (1) | JP2005532388A (pt) |
| KR (1) | KR20050025578A (pt) |
| CN (1) | CN1665537A (pt) |
| AP (1) | AP2004003189A0 (pt) |
| AU (1) | AU2003244921A1 (pt) |
| BR (1) | BR0312421A (pt) |
| CA (1) | CA2488736A1 (pt) |
| EA (1) | EA200401471A1 (pt) |
| EC (1) | ECSP045520A (pt) |
| HR (1) | HRP20041238A2 (pt) |
| IL (1) | IL165328A0 (pt) |
| IS (1) | IS7570A (pt) |
| MA (1) | MA27311A1 (pt) |
| MX (1) | MXPA05000015A (pt) |
| NO (1) | NO20050497L (pt) |
| OA (1) | OA12876A (pt) |
| PL (1) | PL374878A1 (pt) |
| TN (1) | TNSN04268A1 (pt) |
| TW (1) | TW200401768A (pt) |
| WO (1) | WO2004004778A1 (pt) |
| ZA (1) | ZA200409582B (pt) |
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| US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
| US20040132771A1 (en) * | 2002-12-20 | 2004-07-08 | Pfizer Inc | Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors |
| DE60319877T2 (de) * | 2002-12-20 | 2009-04-30 | Pfizer Products Inc., Groton | Dosierungsform enthaltend einen cetp-hemmer und einen hmg-coa reduktase hemmer |
| DE60323536D1 (de) * | 2002-12-20 | 2008-10-23 | Pfizer Prod Inc | Dosierungsform enthaltend einen cetp-hemmer und einen hmg-coa reduktase hemmer |
| EA011009B1 (ru) | 2003-01-14 | 2008-12-30 | Арена Фармасьютикалз Инк. | 1,2,3-тризамещённые арильные и гетероарильные производные в качестве модуляторов метаболизма и профилактика и лечение расстройств, связанных с ним, таких как диабет и гипергликемия |
| JP2006520810A (ja) * | 2003-03-17 | 2006-09-14 | 日本たばこ産業株式会社 | Ｓ−［２−（［［１−（２−エチルブチル）シクロヘキシル］カルボニル］アミノ）フェニル］２−メチルプロパンチオエートの経口吸収性を増加させる方法 |
| PT1603553E (pt) * | 2003-03-17 | 2012-02-03 | Japan Tobacco Inc | Composições farmacêuticas de inibidores de cetp |
| TWI393560B (zh) * | 2003-05-02 | 2013-04-21 | Japan Tobacco Inc | 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合 |
| CA2753318A1 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives |
| AR045697A1 (es) | 2003-07-14 | 2005-11-09 | Arena Pharm Inc | Aril y heteroaril derivados fusionados como moduladores del metabolismo y la prevencion y tratamiento de trastornos relacionados con el mismo |
| JP2007513991A (ja) * | 2003-12-16 | 2007-05-31 | ノバルティス アクチエンゲゼルシャフト | メタボリック症候群の処置のためのスタチンの使用 |
| TW200538127A (en) * | 2004-04-07 | 2005-12-01 | Millennium Pharm Inc | PGD2 receptor antagonists for the treatment of inflammatory diseases |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| WO2007115131A2 (en) * | 2006-03-29 | 2007-10-11 | Guilford F Timothy | Liposomal reduced glutathione and 1-arginine, including other ingredient(s) |
| AU2005305460B2 (en) * | 2004-11-22 | 2011-04-21 | Dexcel Pharma Technologies Ltd. | Stable atorvastatin formulations |
| JP4954085B2 (ja) * | 2004-12-06 | 2012-06-13 | メディシノバ， インコーポレイテッド | 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト |
| WO2006069162A1 (en) * | 2004-12-20 | 2006-06-29 | Reddy Us Therapeutics, Inc. | Novel heterocyclic compounds and their pharmaceutical compositions |
| EP1833466A1 (en) * | 2004-12-28 | 2007-09-19 | Ranbaxy Laboratories Limited | Methods for the preparation of stable pharmaceutical solid dosage forms of atorvastatin and amlodipine |
| US8604055B2 (en) * | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| DK1848430T3 (da) * | 2004-12-31 | 2017-11-06 | Dr Reddys Laboratories Ltd | Nye benzylamin-derivativer som cetp-inhibitors |
| MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| WO2007106111A2 (en) * | 2005-07-01 | 2007-09-20 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising nilvadipine |
| US20090162316A1 (en) * | 2005-07-05 | 2009-06-25 | Harvard University | Liver targeted conjugates |
| SG166829A1 (en) * | 2005-11-08 | 2010-12-29 | Ranbaxy Lab Ltd | Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| US20070238716A1 (en) * | 2006-03-14 | 2007-10-11 | Murthy Ayanampudi S R | Statin stabilizing dosage formulations |
| WO2007116243A2 (en) * | 2006-04-10 | 2007-10-18 | Mintails Limited | Method for treating fibromyalgia and related conditions |
| WO2008010087A2 (en) * | 2006-07-14 | 2008-01-24 | Ranbaxy Laboratories Limited | Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof |
| ES2392116T3 (es) * | 2007-01-30 | 2012-12-04 | Avigen, Inc. | Procedimientos para el tratamiento del dolor agudo y subcrónico |
| WO2008137012A1 (en) * | 2007-05-03 | 2008-11-13 | Avigen, Inc. | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
| EP2158333A4 (en) * | 2007-05-14 | 2010-12-29 | Synvista Therapeutics Inc | USE OF HAPTOGLOBIN ENTYPIZATION FOR DIAGNOSIS AND TREATMENT OF INCORRECT REVERSE CHOLESTER INTRANSPORT |
| WO2009021113A1 (en) * | 2007-08-09 | 2009-02-12 | Holtzman, Jordan, L. | Methods for enhancing glutahione peroxidase activity |
| EP2070520A1 (en) * | 2007-12-11 | 2009-06-17 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media |
| WO2012040279A1 (en) | 2010-09-22 | 2012-03-29 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| EP2626351A4 (en) * | 2010-10-04 | 2014-03-12 | Kowa Co | AGENT CAPABLE OF INHIBITING THE EXPRESSION OF LIPID METABOLISM-RELATED MRNA |
| EP2744803A2 (en) | 2011-08-18 | 2014-06-25 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors |
| CN103958511A (zh) | 2011-09-27 | 2014-07-30 | 雷迪博士实验室有限公司 | 作为胆固醇酯转移蛋白(CETP)抑制剂用于治疗动脉粥样硬化的5-苄基氨基甲基-6-氨基吡唑并[3,4-b]吡啶衍生物 |
| US10300059B2 (en) * | 2014-08-28 | 2019-05-28 | Dezima Pharma B.V. | Pharmaceutical composition and therapeutic combination comprising a cholesteryl ester transfer protein inhibitor and HMG CoA reductase inhibitors |
| MX2021011472A (es) | 2015-01-06 | 2022-08-17 | Arena Pharm Inc | Metodos de condiciones de tratamiento relacionadas con el receptor s1p1. |
| US10301262B2 (en) | 2015-06-22 | 2019-05-28 | Arena Pharmaceuticals, Inc. | Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compund1) for use in SIPI receptor-associated disorders |
| US20190167767A1 (en) * | 2016-07-27 | 2019-06-06 | Hartis-Pharma Sa | Therapeutic combinations to treat red blood cell disorders |
| MX2019009841A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la colangitis biliar primaria. |
| CN116196314B (zh) * | 2023-05-04 | 2023-08-15 | 广州市妇女儿童医疗中心 | Ri-1或其盐在制备防治胃肠道疾病的药物中的应用 |
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| US6144790A (en) * | 1997-02-07 | 2000-11-07 | Bledin; Anthony G | Contact fiber optic impact sensor |
| WO1999011263A1 (en) * | 1997-08-29 | 1999-03-11 | Pfizer Products Inc. | Combination therapy comprising amlodipine and a statin compound |
| GT199800127A (es) * | 1997-08-29 | 2000-02-01 | Combinaciones terapeuticas. | |
| GT199800126A (es) * | 1997-08-29 | 2000-01-29 | Terapia de combinacion. | |
| US6147090A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| GT199900147A (es) * | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
| US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
| US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| US6140342A (en) * | 1998-09-17 | 2000-10-31 | Pfizer Inc. | Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines |
| HN2000000050A (es) * | 1999-05-27 | 2001-02-02 | Pfizer Prod Inc | Sal mutua de amlodipino y atorvastatina |
| PL353483A1 (en) * | 1999-05-27 | 2003-11-17 | Pfizer Products Inc. | Mutual prodrugs of amlodipine and atorvastatin |
| US20030092745A1 (en) * | 2000-02-25 | 2003-05-15 | Pfizer Inc. | Combination therapy |
| US20020013334A1 (en) * | 2000-06-15 | 2002-01-31 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
| SK1742003A3 (en) * | 2000-08-15 | 2004-06-08 | Pfizer Prod Inc | Therapeutic combinations of a CETP inhibitor and atorvastatin |
| US6737430B2 (en) * | 2000-11-09 | 2004-05-18 | Pfizer, Inc. | Mutual prodrug of amlodipine and atorvastatin |
| WO2002087556A2 (en) * | 2001-04-11 | 2002-11-07 | Atherogenics, Inc. | Probucol monoesters and their use to increase plasma hdl cholesterol levels and improve hdl functionality |
| US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
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2003
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- 2003-06-18 MX MXPA05000015A patent/MXPA05000015A/es not_active Application Discontinuation
- 2003-06-18 AU AU2003244921A patent/AU2003244921A1/en not_active Abandoned
- 2003-06-18 OA OA1200400342A patent/OA12876A/en unknown
- 2003-06-18 AP AP2004003189A patent/AP2004003189A0/xx unknown
- 2003-06-18 KR KR1020057000061A patent/KR20050025578A/ko not_active Application Discontinuation
- 2003-06-18 EA EA200401471A patent/EA200401471A1/ru unknown
- 2003-06-18 IL IL16532803A patent/IL165328A0/xx unknown
- 2003-06-18 PL PL03374878A patent/PL374878A1/xx not_active Application Discontinuation
- 2003-06-18 WO PCT/IB2003/002792 patent/WO2004004778A1/en not_active Application Discontinuation
- 2003-06-18 CN CN038155753A patent/CN1665537A/zh active Pending
- 2003-06-18 EP EP03738394A patent/EP1519754A1/en not_active Withdrawn
- 2003-06-18 JP JP2004519080A patent/JP2005532388A/ja not_active Withdrawn
- 2003-06-18 CA CA002488736A patent/CA2488736A1/en not_active Abandoned
- 2003-06-18 BR BR0312421-5A patent/BR0312421A/pt not_active IP Right Cessation
- 2003-07-01 TW TW092117985A patent/TW200401768A/zh unknown
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2004
- 2004-11-26 ZA ZA200409582A patent/ZA200409582B/en unknown
- 2004-11-29 IS IS7570A patent/IS7570A/is unknown
- 2004-12-17 MA MA28016A patent/MA27311A1/fr unknown
- 2004-12-30 HR HR20041238A patent/HRP20041238A2/xx not_active Application Discontinuation
- 2004-12-30 EC EC2004005520A patent/ECSP045520A/es unknown
- 2004-12-30 TN TNP2004000268A patent/TNSN04268A1/fr unknown
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2005
- 2005-01-28 NO NO20050497A patent/NO20050497L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20040053842A1 (en) | 2004-03-18 |
| BR0312421A (pt) | 2005-04-19 |
| CN1665537A (zh) | 2005-09-07 |
| JP2005532388A (ja) | 2005-10-27 |
| OA12876A (en) | 2006-09-15 |
| AU2003244921A1 (en) | 2004-01-23 |
| EP1519754A1 (en) | 2005-04-06 |
| WO2004004778A1 (en) | 2004-01-15 |
| HRP20041238A2 (en) | 2005-06-30 |
| AP2004003189A0 (en) | 2004-12-31 |
| NO20050497L (no) | 2005-03-08 |
| ECSP045520A (es) | 2005-03-10 |
| PL374878A1 (en) | 2005-11-14 |
| MA27311A1 (fr) | 2005-05-02 |
| KR20050025578A (ko) | 2005-03-14 |
| IS7570A (is) | 2004-11-29 |
| CA2488736A1 (en) | 2004-01-15 |
| IL165328A0 (en) | 2006-01-15 |
| MXPA05000015A (es) | 2005-04-08 |
| EA200401471A1 (ru) | 2005-06-30 |
| TNSN04268A1 (fr) | 2007-03-12 |
| TW200401768A (en) | 2004-02-01 |
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