ZA200405380B - Pyrimidine-based compounds useful as GSK-3 inhibitors. - Google Patents

Pyrimidine-based compounds useful as GSK-3 inhibitors. Download PDF

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Publication number
ZA200405380B
ZA200405380B ZA200405380A ZA200405380A ZA200405380B ZA 200405380 B ZA200405380 B ZA 200405380B ZA 200405380 A ZA200405380 A ZA 200405380A ZA 200405380 A ZA200405380 A ZA 200405380A ZA 200405380 B ZA200405380 B ZA 200405380B
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South Africa
Prior art keywords
ring
optionally substituted
aliphatic
disease
compound
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ZA200405380A
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English (en)
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Deborah Choquette
Robert J Davies
Marion W Wannamaker
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Vertex Pharma
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Publication of ZA200405380B publication Critical patent/ZA200405380B/en

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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D239/72—Quinazolines; Hydrogenated quinazolines
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/10—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with an aromatic or hetero-aromatic ring directly attached in position 2
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    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
ZA200405380A 2001-12-07 2004-07-06 Pyrimidine-based compounds useful as GSK-3 inhibitors. ZA200405380B (en)

Applications Claiming Priority (1)

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US33885701P 2001-12-07 2001-12-07

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ZA200405380B true ZA200405380B (en) 2005-06-17

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ZA200405380A ZA200405380B (en) 2001-12-07 2004-07-06 Pyrimidine-based compounds useful as GSK-3 inhibitors.

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US (1) US20030199526A1 (ja)
EP (2) EP2198867A1 (ja)
JP (2) JP2005516005A (ja)
AT (1) ATE466581T1 (ja)
AU (1) AU2002364536B2 (ja)
CA (1) CA2469316A1 (ja)
DE (1) DE60236322D1 (ja)
MX (1) MXPA04005510A (ja)
WO (1) WO2003049739A1 (ja)
ZA (1) ZA200405380B (ja)

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