ZA200405239B - Process for the manufacture of organic compounds - Google Patents

Process for the manufacture of organic compounds

Info

Publication number
ZA200405239B
ZA200405239B ZA2004/05239A ZA200405239A ZA200405239B ZA 200405239 B ZA200405239 B ZA 200405239B ZA 2004/05239 A ZA2004/05239 A ZA 2004/05239A ZA 200405239 A ZA200405239 A ZA 200405239A ZA 200405239 B ZA200405239 B ZA 200405239B
Authority
ZA
South Africa
Prior art keywords
manufacture
organic compounds
compounds
organic
Prior art date
Application number
ZA2004/05239A
Other languages
English (en)
Inventor
Beutler Ulrich
Zaugg Werner
Koteswara Kapa Prasad
M Loeser Eric
Chen Guang-Pei
J Girgis Michael
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200405239B publication Critical patent/ZA200405239B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
  • Cephalosporin Compounds (AREA)
ZA2004/05239A 2002-01-28 2004-07-01 Process for the manufacture of organic compounds ZA200405239B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35231602P 2002-01-28 2002-01-28
US38318802P 2002-05-24 2002-05-24
PCT/EP2003/000804 WO2003064382A2 (en) 2002-01-28 2003-01-27 Process for the manufacture of organic compounds

Publications (1)

Publication Number Publication Date
ZA200405239B true ZA200405239B (en) 2005-07-27

Family

ID=27669055

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2004/05239A ZA200405239B (en) 2002-01-28 2004-07-01 Process for the manufacture of organic compounds

Country Status (19)

Country Link
US (3) US6835838B2 (https=)
EP (1) EP1472227B1 (https=)
JP (1) JP2005516064A (https=)
KR (2) KR20100091267A (https=)
CN (2) CN1625550A (https=)
AU (4) AU2003239294B2 (https=)
BR (1) BR0307236A (https=)
CA (1) CA2472340A1 (https=)
CO (1) CO5601045A2 (https=)
EC (1) ECSP045202A (https=)
IL (1) IL162817A0 (https=)
MX (1) MXPA04007308A (https=)
NO (1) NO327363B1 (https=)
NZ (3) NZ554367A (https=)
PL (1) PL371383A1 (https=)
RU (1) RU2360903C2 (https=)
SG (2) SG157225A1 (https=)
WO (1) WO2003064382A2 (https=)
ZA (1) ZA200405239B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL159741A0 (en) 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
EP1466905B1 (en) * 2001-11-14 2011-05-18 Nissan Chemical Industries, Ltd. Process for producing optically active oxoheptenoic acid ester
AU2003226971B2 (en) * 2002-01-31 2006-11-30 Novartis Ag Process for the manufacture of HMG-CoA reductase inhibitors
US7339062B2 (en) * 2002-09-20 2008-03-04 Nissan Chemical Industries, Ltd. Method for producing a 3,5-dihydroxy-6-heptenoate
DE202004021379U1 (de) * 2003-02-12 2008-02-21 Ciba Specialty Chemicals Holding Inc. Kristalline Formen von Pitivastatin Calcium
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
CN1763015B (zh) * 2004-10-22 2011-06-22 四川抗菌素工业研究所有限公司 一种罗舒伐他汀及其药用盐的制备方法及中间体
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
GB0514078D0 (en) 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
US8455640B2 (en) * 2006-05-03 2013-06-04 Msn Laboratories Limited Process for statins and its pharmaceutically acceptable salts thereof
US8404841B2 (en) * 2006-10-09 2013-03-26 Msn Laboratories Limited Process for the preparation of statins and their pharmaceutically acceptable salts thereof
TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process
US8487105B2 (en) * 2009-01-19 2013-07-16 Msn Laboratories Limited Process for preparing pitavastatin, intermediates and pharmaceuctically acceptable salts thereof
RU2425034C1 (ru) * 2010-01-11 2011-07-27 Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") Способ получения производных (e)-4-(6,7-диметокси-2-метил-3-хинолил)-3-бутен-2-она
WO2011086584A2 (en) 2010-01-18 2011-07-21 Msn Laboratories Limited Improved process for the preparation of amide intermediates and their use thereof
EP2423195A1 (en) 2010-07-26 2012-02-29 LEK Pharmaceuticals d.d. Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
WO2012025939A1 (en) * 2010-08-25 2012-03-01 Cadila Healthcare Limited Pitavastatin calcium and process for its preparation
EP3178812A1 (en) * 2010-11-12 2017-06-14 Hetero Research Foundation Novel polymorphs of pitavastatin calcium
WO2012140490A2 (en) 2011-04-11 2012-10-18 Aurobindo Pharma Limited Process for preparing quinoline derivative
CN103755568B (zh) * 2013-12-10 2015-10-28 江西科技师范大学 IeodomycinA和B立体选择性合成方法
CN107949556B (zh) 2015-08-05 2021-12-07 株式会社Api 生产匹伐他汀钙的方法
CN108976168B (zh) * 2017-06-02 2020-09-25 浙江京新药业股份有限公司 一种匹伐他汀半钙盐晶型及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906624A (en) * 1987-09-08 1990-03-06 Warner-Lambert Company 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
NZ230121A (en) * 1988-08-29 1993-08-26 Squibb & Sons Inc Pyridine and quinoline terminal groups for hmg-coenzyme a reductase inhibitors and pharmaceutical compositions for lowering blood serum cholesterol levels
JP3528186B2 (ja) 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
JP3130342B2 (ja) * 1991-10-04 2001-01-31 日産化学工業株式会社 動脈硬化性血管内膜肥厚抑制薬
JP3554036B2 (ja) * 1994-09-06 2004-08-11 宇部興産株式会社 光学活性な7−置換キノリル−3,5−ジヒドロキシ−ヘプト−6−エン酸エステル誘導体の製造方法
EP1466905B1 (en) * 2001-11-14 2011-05-18 Nissan Chemical Industries, Ltd. Process for producing optically active oxoheptenoic acid ester
ES2385623T3 (es) * 2007-02-08 2012-07-27 Aurobindo Pharma Limited Un procedimiento mejorado para la preparación de rosuvastatina cálcica

Also Published As

Publication number Publication date
AU2006225206A1 (en) 2006-10-26
US20040249154A1 (en) 2004-12-09
KR20040077883A (ko) 2004-09-07
JP2005516064A (ja) 2005-06-02
CA2472340A1 (en) 2003-08-07
EP1472227B1 (en) 2016-04-27
PL371383A1 (en) 2005-06-13
NO20043586L (no) 2004-10-07
AU2006225205B2 (en) 2009-08-06
NZ534136A (en) 2007-08-31
NO327363B1 (no) 2009-06-15
EP1472227A2 (en) 2004-11-03
US6835838B2 (en) 2004-12-28
BR0307236A (pt) 2004-12-07
AU2009208129A1 (en) 2009-09-03
AU2003239294B2 (en) 2006-10-19
CN1625550A (zh) 2005-06-08
RU2004126448A (ru) 2005-06-27
KR20100091267A (ko) 2010-08-18
AU2006225206B2 (en) 2009-08-06
NZ554366A (en) 2008-11-28
SG157225A1 (en) 2009-12-29
US20090299065A1 (en) 2009-12-03
MXPA04007308A (es) 2004-10-29
CO5601045A2 (es) 2006-01-31
IL162817A0 (en) 2005-11-20
AU2006225205A1 (en) 2006-10-26
US20030208072A1 (en) 2003-11-06
ECSP045202A (es) 2004-09-28
RU2360903C2 (ru) 2009-07-10
CN1660818A (zh) 2005-08-31
WO2003064382A2 (en) 2003-08-07
NZ554367A (en) 2008-11-28
US7572917B2 (en) 2009-08-11
SG161742A1 (en) 2010-06-29
CN100378081C (zh) 2008-04-02
WO2003064382A3 (en) 2003-12-11

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