ZA200403184B - Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. - Google Patents

Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. Download PDF

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Publication number
ZA200403184B
ZA200403184B ZA200403184A ZA200403184A ZA200403184B ZA 200403184 B ZA200403184 B ZA 200403184B ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 B ZA200403184 B ZA 200403184B
Authority
ZA
South Africa
Prior art keywords
vascular
arterial graft
venous
methyl
shunt
Prior art date
Application number
ZA200403184A
Other languages
English (en)
Inventor
Matthew R Wolff
Stoker Scott William
Griffin Michael Orrin
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of ZA200403184B publication Critical patent/ZA200403184B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200403184A 2001-10-25 2004-04-28 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. ZA200403184B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34373201P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ZA200403184B true ZA200403184B (en) 2005-05-12

Family

ID=23347387

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200403184A ZA200403184B (en) 2001-10-25 2004-04-28 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same.

Country Status (18)

Country Link
US (1) US20040044405A1 (pt)
EP (1) EP1441749A4 (pt)
JP (1) JP2006519623A (pt)
KR (1) KR20040051618A (pt)
CN (1) CN1635858A (pt)
BR (1) BR0213497A (pt)
CA (1) CA2464093A1 (pt)
CO (1) CO5580792A2 (pt)
EC (1) ECSP045085A (pt)
HU (1) HUP0402036A3 (pt)
IL (1) IL161583A0 (pt)
MX (1) MXPA04003906A (pt)
NO (1) NO20042133L (pt)
NZ (1) NZ532593A (pt)
PL (1) PL374315A1 (pt)
RU (1) RU2004116068A (pt)
WO (1) WO2003034938A2 (pt)
ZA (1) ZA200403184B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2490989A1 (en) * 2002-05-13 2003-11-20 Beth Israel Deaconess Medical Center Methods and compositions for the treatment of graft failure
JP4353481B2 (ja) 2002-06-26 2009-10-28 クック インコーポレイティド ステントグラフト固定装置
US20050214343A1 (en) * 2002-07-18 2005-09-29 Patrice Tremble Medical devices comprising a protein-tyrosine kinase inhibitor to inhibit restonosis
EP1635815A4 (en) * 2003-06-03 2009-03-25 Beth Israel Hospital METHOD AND COMPOUNDS FOR TREATING TISSUE TESTS
WO2005095641A1 (en) * 2004-03-03 2005-10-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 11 (map3k11)
KR20070001995A (ko) 2004-03-05 2007-01-04 리지너크스 바이오 파마소티컬스, 인코포레이티드 세포외 매트릭스 축적의 치료 또는 예방법
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
WO2007033152A2 (en) * 2005-09-12 2007-03-22 Conor Medsystems, Inc. Composition, system and method for modulating release kinetics in implantable drug delivery devices by modifying drug solubility
US20070196428A1 (en) * 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
JP5110559B2 (ja) * 2006-11-24 2012-12-26 学校法人近畿大学 被覆ステント
CA2708241A1 (en) 2007-12-07 2009-06-18 Vertex Pharmaceuticals Incorporated Solid forms of 1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1h-benzo[d]imidazol-2-yl)urea
US9126025B2 (en) * 2008-05-01 2015-09-08 Bayer Intellectual Property Gmbh Method of coating a folded catheter balloon
CA2752544A1 (en) 2009-02-13 2010-08-19 Vertex Pharmaceuticals Incorporated Solid forms of 2-(2, 4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US20110319987A1 (en) 2009-05-20 2011-12-29 Arsenal Medical Medical implant
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
ES2968361T3 (es) * 2009-05-20 2024-05-09 Lyra Therapeutics Inc Un método para elaborar un implante autoexpandible
US8372133B2 (en) * 2009-10-05 2013-02-12 480 Biomedical, Inc. Polymeric implant delivery system
CN103443096B (zh) 2011-01-14 2016-06-29 沃泰克斯药物股份有限公司 促旋酶和拓扑异构酶iv抑制剂
TWI535714B (zh) 2011-01-14 2016-06-01 維泰克斯製藥公司 旋轉酶抑制劑(r)-1-乙基-3-[6-氟-5-[2-(1-羥基-1-甲基-乙基)嘧啶-5-基]-7-(四氫呋喃-2-基)-1h-苯并咪唑-2-基]脲之固體形式
US9187953B2 (en) 2011-03-23 2015-11-17 Rytec Corporation Side column configuration for overhead roll-up door assemblies
EP2721026B1 (en) 2011-06-20 2016-03-02 Vertex Pharmaceuticals Incorporated Phosphate esters of gyrase and topoisomerase inhibitors
WO2013003157A1 (en) * 2011-06-28 2013-01-03 Yale University Cell-free tissued engineered vascular grafts
TWI595002B (zh) 2012-07-18 2017-08-11 思沛羅三南公司 (R)-2-(5-(2-(3-乙基脲基)-6-氟-7-(四氫呋喃-2-基)-1H-苯并[d]咪唑-5-基)嘧啶-2-基)丙烷-2-基磷酸二氫鹽之固體形式及其鹽
ES2705342T3 (es) 2013-10-17 2019-03-22 Vertex Pharma Co-cristales de (S)-N-metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il)amino)propan-2-il)quinolin-4-carboxamida y derivados deuterados de la misma como inhibidores de DNA-PK
CA3007631A1 (en) 2015-12-11 2017-06-15 Research Institute At Nationwide Children's Hospital Optimized patient specific non-linear tissue engineered vascular grafts
US11628239B2 (en) 2016-11-04 2023-04-18 University Of Delaware Method for protecting skeletonized blood vessels

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824436A (en) * 1985-04-09 1989-04-25 Harvey Wolinsky Method for the prevention of restenosis
US5171217A (en) * 1991-02-28 1992-12-15 Indiana University Foundation Method for delivery of smooth muscle cell inhibitors
US5521184A (en) * 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
US6306421B1 (en) * 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5354774A (en) * 1992-12-24 1994-10-11 Yale University Inhibition of smooth muscle cell proliferation by 8-methoxypsoralen photoactivated by visible light
US5279565A (en) * 1993-02-03 1994-01-18 Localmed, Inc. Intravascular treatment apparatus and method
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US5788979A (en) * 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
US6306165B1 (en) * 1996-09-13 2001-10-23 Meadox Medicals ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
US6245760B1 (en) * 1997-05-28 2001-06-12 Aventis Pharmaceuticals Products, Inc Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
CO4940418A1 (es) * 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
JP2002517435A (ja) * 1998-06-11 2002-06-18 シーラス コーポレイション 動脈平滑筋細胞の増殖阻害のためのアルキル化化合物の使用
EP1257546A1 (en) * 2000-02-17 2002-11-20 Amgen Inc. Kinase inhibitors
WO2002045717A1 (en) * 2000-12-06 2002-06-13 Tularik Inc. Lometrexol combination therapy
US6872715B2 (en) * 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins

Also Published As

Publication number Publication date
CA2464093A1 (en) 2003-05-01
NO20042133L (no) 2004-07-09
BR0213497A (pt) 2006-05-23
RU2004116068A (ru) 2005-03-20
HUP0402036A3 (en) 2008-04-28
IL161583A0 (en) 2004-09-27
EP1441749A2 (en) 2004-08-04
PL374315A1 (en) 2005-10-03
HUP0402036A2 (hu) 2005-02-28
WO2003034938A3 (en) 2003-11-13
NZ532593A (en) 2007-11-30
US20040044405A1 (en) 2004-03-04
ECSP045085A (es) 2004-07-23
CN1635858A (zh) 2005-07-06
JP2006519623A (ja) 2006-08-31
CO5580792A2 (es) 2005-11-30
EP1441749A4 (en) 2010-05-19
KR20040051618A (ko) 2004-06-18
MXPA04003906A (es) 2005-02-17
WO2003034938A2 (en) 2003-05-01

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