BR0213497A - sonda vascular ou enxerto revestido ou impregnado com inibidores de proteìna tirosina cinase e método para usar o mesmo - Google Patents

sonda vascular ou enxerto revestido ou impregnado com inibidores de proteìna tirosina cinase e método para usar o mesmo

Info

Publication number
BR0213497A
BR0213497A BRPI0213497-7A BR0213497A BR0213497A BR 0213497 A BR0213497 A BR 0213497A BR 0213497 A BR0213497 A BR 0213497A BR 0213497 A BR0213497 A BR 0213497A
Authority
BR
Brazil
Prior art keywords
vascular
tyrosine kinase
protein tyrosine
probe
impregnated
Prior art date
Application number
BRPI0213497-7A
Other languages
English (en)
Inventor
Matthew R Wolff
Scott William Stoker
Michael Orrin Griffin
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of BR0213497A publication Critical patent/BR0213497A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"SONDA VASCULAR OU ENXERTO REVESTIDO OU IMPREGNADO COM INIBIDORES DE PROTEìNA TIROSINA CINASE E MéTODO PARA USAR O MESMO". A presente invenção refere-se a um dispositivo, como uma sonda cardiovascular, enxerto venoso/ arterial autólogo, enxerto venoso/ arterial protético, cateter vascular ou derivação vascular, destinado à colocação de uma sonda em um vaso sangüíneo. O dispositivo tem revestido sobre o mesmo, adsorvido no mesmo, impregnado no mesmo, ou covalentemente ou ionicamente ligado ao mesmo uma quantidade de um inibidor de proteína tirosina cinase. O inibidor de proteína tirosina cinase inibe a proliferação de células de músculo liso vascular em uma área dentro de um vaso sangüíneo imediatamente adjacente a e/ou proximal do dispositivo, enquanto simultaneamente não inibindo a proliferação de células das íntimas vasculares. Um método correspondente para usar o dispositivo destinado à colocação de sondas em vasos sangüíneos é também descrito.
BRPI0213497-7A 2001-10-25 2002-10-25 sonda vascular ou enxerto revestido ou impregnado com inibidores de proteìna tirosina cinase e método para usar o mesmo BR0213497A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34373201P 2001-10-25 2001-10-25
PCT/US2002/034344 WO2003034938A2 (en) 2001-10-25 2002-10-25 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same

Publications (1)

Publication Number Publication Date
BR0213497A true BR0213497A (pt) 2006-05-23

Family

ID=23347387

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0213497-7A BR0213497A (pt) 2001-10-25 2002-10-25 sonda vascular ou enxerto revestido ou impregnado com inibidores de proteìna tirosina cinase e método para usar o mesmo

Country Status (18)

Country Link
US (1) US20040044405A1 (pt)
EP (1) EP1441749A4 (pt)
JP (1) JP2006519623A (pt)
KR (1) KR20040051618A (pt)
CN (1) CN1635858A (pt)
BR (1) BR0213497A (pt)
CA (1) CA2464093A1 (pt)
CO (1) CO5580792A2 (pt)
EC (1) ECSP045085A (pt)
HU (1) HUP0402036A3 (pt)
IL (1) IL161583A0 (pt)
MX (1) MXPA04003906A (pt)
NO (1) NO20042133L (pt)
NZ (1) NZ532593A (pt)
PL (1) PL374315A1 (pt)
RU (1) RU2004116068A (pt)
WO (1) WO2003034938A2 (pt)
ZA (1) ZA200403184B (pt)

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ATE533433T1 (de) 2002-06-26 2011-12-15 Cook Medical Technologies Llc Stent-graft befestigung
US20050214343A1 (en) * 2002-07-18 2005-09-29 Patrice Tremble Medical devices comprising a protein-tyrosine kinase inhibitor to inhibit restonosis
JP2006526652A (ja) * 2003-06-03 2006-11-24 ベス・イスラエル・ディーコニス・メディカル・センター 血管狭窄を治療するための方法及び化合物
WO2005095641A1 (en) * 2004-03-03 2005-10-13 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 11 (map3k11)
US8399609B2 (en) 2004-03-05 2013-03-19 Regenerx Biopharmaceuticals, Inc. Treating or preventing extracellular matrix build-up
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
WO2007033152A2 (en) * 2005-09-12 2007-03-22 Conor Medsystems, Inc. Composition, system and method for modulating release kinetics in implantable drug delivery devices by modifying drug solubility
US20070196428A1 (en) 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
JP5110559B2 (ja) * 2006-11-24 2012-12-26 学校法人近畿大学 被覆ステント
WO2009076200A2 (en) 2007-12-07 2009-06-18 Vertex Pharmaceuticals Incorporated Solid forms of 1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1h-benzo[d]imidazol-2-yl)urea
WO2009135125A2 (en) * 2008-05-01 2009-11-05 Bayer Schering Pharma Ag Catheter balloon drug adherence techniques and methods
WO2010093889A2 (en) 2009-02-13 2010-08-19 Vertex Pharmaceuticals Incorporated Solid forms of 2-(2, 4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
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US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
US20110319987A1 (en) 2009-05-20 2011-12-29 Arsenal Medical Medical implant
CA3186201A1 (en) * 2009-05-20 2010-11-25 Lyra Therapeutics, Inc. Self-expandable medical device comprising polymeric strands and coatings thereon
US8372133B2 (en) * 2009-10-05 2013-02-12 480 Biomedical, Inc. Polymeric implant delivery system
MX341342B (es) 2011-01-14 2016-08-17 Vertex Pharma Formas solidas del inhibidor de girasa (r)-1-etil-3-[6-fluoro-5-[2 -(1-hidroxi-1-metil-etil) pirimidin-5-il]-7-(tetrahidrofuran-2-il) -1h-benzimidazol-2-il]urea.
KR101897952B1 (ko) 2011-01-14 2018-09-12 스페로 트리넴, 인코포레이티드 피리미딘 자이라제 및 토포이소머라제 ｉｖ 억제제
US9187953B2 (en) 2011-03-23 2015-11-17 Rytec Corporation Side column configuration for overhead roll-up door assemblies
KR101941420B1 (ko) 2011-06-20 2019-01-23 스페로 트리넴, 인코포레이티드 자이라제 및 토포이소머라제 억제제의 인산에스테르
US9326951B2 (en) 2011-06-28 2016-05-03 Yale University Cell-free tissue engineered vascular grafts
WO2014015105A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
PL3424920T3 (pl) 2013-10-17 2020-11-16 Vertex Pharmaceuticals Incorporated Kokryształy (S)-N-metylo-8-(1-((2'-metylo-4’,6'-dideutero-[4,5'-bipirymidyn]-6-ylo)amino)propan-2-ylo)chinolino-4-karboksyamidu i ich deuterowane pochodne jako inhibitory DNA-PK
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Also Published As

Publication number Publication date
WO2003034938A3 (en) 2003-11-13
IL161583A0 (en) 2004-09-27
MXPA04003906A (es) 2005-02-17
NZ532593A (en) 2007-11-30
HUP0402036A2 (hu) 2005-02-28
US20040044405A1 (en) 2004-03-04
WO2003034938A2 (en) 2003-05-01
HUP0402036A3 (en) 2008-04-28
CO5580792A2 (es) 2005-11-30
ZA200403184B (en) 2005-05-12
EP1441749A4 (en) 2010-05-19
NO20042133L (no) 2004-07-09
CA2464093A1 (en) 2003-05-01
JP2006519623A (ja) 2006-08-31
KR20040051618A (ko) 2004-06-18
ECSP045085A (es) 2004-07-23
EP1441749A2 (en) 2004-08-04
RU2004116068A (ru) 2005-03-20
CN1635858A (zh) 2005-07-06
PL374315A1 (en) 2005-10-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.