ZA200403184B - Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. - Google Patents
Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. Download PDFInfo
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- ZA200403184B ZA200403184B ZA200403184A ZA200403184A ZA200403184B ZA 200403184 B ZA200403184 B ZA 200403184B ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 A ZA200403184 A ZA 200403184A ZA 200403184 B ZA200403184 B ZA 200403184B
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- South Africa
- Prior art keywords
- vascular
- arterial graft
- venous
- methyl
- shunt
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34373201P | 2001-10-25 | 2001-10-25 |
Publications (1)
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|---|---|
| ZA200403184B true ZA200403184B (en) | 2005-05-12 |
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| ZA200403184A ZA200403184B (en) | 2001-10-25 | 2004-04-28 | Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and methods of using same. |
Country Status (18)
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| US (1) | US20040044405A1 (hu) |
| EP (1) | EP1441749A4 (hu) |
| JP (1) | JP2006519623A (hu) |
| KR (1) | KR20040051618A (hu) |
| CN (1) | CN1635858A (hu) |
| BR (1) | BR0213497A (hu) |
| CA (1) | CA2464093A1 (hu) |
| CO (1) | CO5580792A2 (hu) |
| EC (1) | ECSP045085A (hu) |
| HU (1) | HUP0402036A3 (hu) |
| IL (1) | IL161583A0 (hu) |
| MX (1) | MXPA04003906A (hu) |
| NO (1) | NO20042133L (hu) |
| NZ (1) | NZ532593A (hu) |
| PL (1) | PL374315A1 (hu) |
| RU (1) | RU2004116068A (hu) |
| WO (1) | WO2003034938A2 (hu) |
| ZA (1) | ZA200403184B (hu) |
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| EP1509219A1 (en) * | 2002-05-13 | 2005-03-02 | Beth Israel Deaconess Medical Center | Methods and compositions for the treatment of graft failure |
| AU2003247634B2 (en) | 2002-06-26 | 2008-07-17 | Cook Incorporated | Stent-graft fastening |
| US20050214343A1 (en) * | 2002-07-18 | 2005-09-29 | Patrice Tremble | Medical devices comprising a protein-tyrosine kinase inhibitor to inhibit restonosis |
| WO2004108130A1 (en) * | 2003-06-03 | 2004-12-16 | Beth Israel Deaconess Medical Center | Methods and compounds for the treatment of vascular stenosis |
| WO2005095641A1 (en) * | 2004-03-03 | 2005-10-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with mitogen-activated protein kinase kinase kinase 11 (map3k11) |
| US8399609B2 (en) | 2004-03-05 | 2013-03-19 | Regenerx Biopharmaceuticals, Inc. | Treating or preventing extracellular matrix build-up |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| US20070065477A1 (en) * | 2005-09-12 | 2007-03-22 | Conor Medsystems, Inc. | Composition, system, and method for modulating release kinetics in implantable drug delivery devices by modifying drug solubility |
| US20070196428A1 (en) * | 2006-02-17 | 2007-08-23 | Thierry Glauser | Nitric oxide generating medical devices |
| JP5110559B2 (ja) * | 2006-11-24 | 2012-12-26 | 学校法人近畿大学 | 被覆ステント |
| US8217172B2 (en) | 2007-12-07 | 2012-07-10 | Vertex Pharmaceuticals Incorporated | Solid forms of 1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea |
| EP3159033B1 (en) * | 2008-05-01 | 2019-02-27 | Bayer Intellectual Property GmbH | Catheter balloon drug adherence techniques and methods |
| WO2010093889A2 (en) | 2009-02-13 | 2010-08-19 | Vertex Pharmaceuticals Incorporated | Solid forms of 2-(2, 4-difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide |
| US9265633B2 (en) | 2009-05-20 | 2016-02-23 | 480 Biomedical, Inc. | Drug-eluting medical implants |
| US9309347B2 (en) | 2009-05-20 | 2016-04-12 | Biomedical, Inc. | Bioresorbable thermoset polyester/urethane elastomers |
| US8992601B2 (en) | 2009-05-20 | 2015-03-31 | 480 Biomedical, Inc. | Medical implants |
| CA3186201A1 (en) * | 2009-05-20 | 2010-11-25 | Lyra Therapeutics, Inc. | Self-expandable medical device comprising polymeric strands and coatings thereon |
| US20110319987A1 (en) | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
| US8888840B2 (en) * | 2009-05-20 | 2014-11-18 | Boston Scientific Scimed, Inc. | Drug eluting medical implant |
| US8372133B2 (en) * | 2009-10-05 | 2013-02-12 | 480 Biomedical, Inc. | Polymeric implant delivery system |
| AU2012205419B2 (en) | 2011-01-14 | 2016-12-15 | Spero Therapeutics, Inc. | Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea |
| EP2663557B1 (en) | 2011-01-14 | 2015-05-27 | Vertex Pharmaceuticals Incorporated | Pyrimidine gyrase and topoisomerase iv inhibitors |
| US9187953B2 (en) | 2011-03-23 | 2015-11-17 | Rytec Corporation | Side column configuration for overhead roll-up door assemblies |
| JP5977344B2 (ja) | 2011-06-20 | 2016-08-24 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | ジャイレースおよびトポイソメラーゼ阻害剤のリン酸エステル |
| WO2013003157A1 (en) | 2011-06-28 | 2013-01-03 | Yale University | Cell-free tissued engineered vascular grafts |
| US9018216B2 (en) | 2012-07-18 | 2015-04-28 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof |
| PT3424920T (pt) | 2013-10-17 | 2020-07-07 | Vertex Pharma | Co-cristais de (s)-n-metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il)amino)propan-2-il)quinolina-4-carboxamida e derivados deuterados dos mesmos como inibidores de adn-pk |
| CN108601863A (zh) | 2015-12-11 | 2018-09-28 | 国家儿童医院研究所 | 用于优化的患者特异性组织工程化血管移植物的系统和方法 |
| US11628239B2 (en) | 2016-11-04 | 2023-04-18 | University Of Delaware | Method for protecting skeletonized blood vessels |
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| US4824436A (en) * | 1985-04-09 | 1989-04-25 | Harvey Wolinsky | Method for the prevention of restenosis |
| US5171217A (en) * | 1991-02-28 | 1992-12-15 | Indiana University Foundation | Method for delivery of smooth muscle cell inhibitors |
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US6306421B1 (en) * | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5354774A (en) * | 1992-12-24 | 1994-10-11 | Yale University | Inhibition of smooth muscle cell proliferation by 8-methoxypsoralen photoactivated by visible light |
| US5279565A (en) * | 1993-02-03 | 1994-01-18 | Localmed, Inc. | Intravascular treatment apparatus and method |
| US5788687A (en) * | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
| US5788979A (en) * | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
| US6306165B1 (en) * | 1996-09-13 | 2001-10-23 | Meadox Medicals | ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin |
| US6245760B1 (en) * | 1997-05-28 | 2001-06-12 | Aventis Pharmaceuticals Products, Inc | Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases |
| CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| US6281225B1 (en) * | 1998-06-11 | 2001-08-28 | Cerus Corporation | Inhibiting proliferation of arterial smooth muscle cells |
| CN1429222A (zh) * | 2000-02-17 | 2003-07-09 | 安姆根有限公司 | 激酶抑制剂 |
| US20020156023A1 (en) * | 2000-12-06 | 2002-10-24 | Tularik Inc. | Lometrexol combination therapy |
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
-
2002
- 2002-10-25 CA CA002464093A patent/CA2464093A1/en not_active Abandoned
- 2002-10-25 WO PCT/US2002/034344 patent/WO2003034938A2/en active Application Filing
- 2002-10-25 RU RU2004116068/14A patent/RU2004116068A/ru not_active Application Discontinuation
- 2002-10-25 HU HU0402036A patent/HUP0402036A3/hu unknown
- 2002-10-25 NZ NZ532593A patent/NZ532593A/en unknown
- 2002-10-25 BR BRPI0213497-7A patent/BR0213497A/pt not_active IP Right Cessation
- 2002-10-25 JP JP2003537510A patent/JP2006519623A/ja active Pending
- 2002-10-25 PL PL02374315A patent/PL374315A1/xx not_active Application Discontinuation
- 2002-10-25 IL IL16158302A patent/IL161583A0/xx unknown
- 2002-10-25 KR KR10-2004-7006059A patent/KR20040051618A/ko not_active Application Discontinuation
- 2002-10-25 EP EP02784295A patent/EP1441749A4/en not_active Withdrawn
- 2002-10-25 US US10/280,576 patent/US20040044405A1/en not_active Abandoned
- 2002-10-25 MX MXPA04003906A patent/MXPA04003906A/es not_active Application Discontinuation
- 2002-10-25 CN CNA028211502A patent/CN1635858A/zh active Pending
-
2004
- 2004-04-23 EC EC2004005085A patent/ECSP045085A/es unknown
- 2004-04-28 ZA ZA200403184A patent/ZA200403184B/en unknown
- 2004-05-24 NO NO20042133A patent/NO20042133L/no not_active Application Discontinuation
- 2004-05-25 CO CO04048129A patent/CO5580792A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003034938A3 (en) | 2003-11-13 |
| MXPA04003906A (es) | 2005-02-17 |
| BR0213497A (pt) | 2006-05-23 |
| HUP0402036A2 (hu) | 2005-02-28 |
| NO20042133L (no) | 2004-07-09 |
| CO5580792A2 (es) | 2005-11-30 |
| CA2464093A1 (en) | 2003-05-01 |
| HUP0402036A3 (en) | 2008-04-28 |
| JP2006519623A (ja) | 2006-08-31 |
| IL161583A0 (en) | 2004-09-27 |
| EP1441749A4 (en) | 2010-05-19 |
| CN1635858A (zh) | 2005-07-06 |
| US20040044405A1 (en) | 2004-03-04 |
| PL374315A1 (en) | 2005-10-03 |
| WO2003034938A2 (en) | 2003-05-01 |
| EP1441749A2 (en) | 2004-08-04 |
| KR20040051618A (ko) | 2004-06-18 |
| NZ532593A (en) | 2007-11-30 |
| RU2004116068A (ru) | 2005-03-20 |
| ECSP045085A (es) | 2004-07-23 |
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