ZA200309632B - Medicinal composition for treatment of interstitial cystitis. - Google Patents
Medicinal composition for treatment of interstitial cystitis. Download PDFInfo
- Publication number
- ZA200309632B ZA200309632B ZA200309632A ZA200309632A ZA200309632B ZA 200309632 B ZA200309632 B ZA 200309632B ZA 200309632 A ZA200309632 A ZA 200309632A ZA 200309632 A ZA200309632 A ZA 200309632A ZA 200309632 B ZA200309632 B ZA 200309632B
- Authority
- ZA
- South Africa
- Prior art keywords
- capsaicin
- carboxylate
- interstitial cystitis
- acid
- salt
- Prior art date
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- 239000000203 mixture Substances 0.000 title description 7
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- 239000000314 lubricant Substances 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229940098779 methanesulfonic acid Drugs 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 239000003149 muscarinic antagonist Substances 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 206010029446 nocturia Diseases 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 238000001543 one-way ANOVA Methods 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000012044 organic layer Substances 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 102000054765 polymorphisms of proteins Human genes 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000001020 rhythmical effect Effects 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 125000005490 tosylate group Chemical group 0.000 description 1
- 150000008648 triflates Chemical class 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
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- 239000003981 vehicle Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001209041 | 2001-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200309632B true ZA200309632B (en) | 2004-12-22 |
Family
ID=19044753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200309632A ZA200309632B (en) | 2001-07-10 | 2002-07-08 | Medicinal composition for treatment of interstitial cystitis. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7335668B2 (ko) |
| EP (1) | EP1405638B1 (ko) |
| JP (1) | JP4174673B2 (ko) |
| KR (1) | KR100874815B1 (ko) |
| CN (1) | CN1270708C (ko) |
| AT (1) | ATE497765T1 (ko) |
| AU (1) | AU2002315814B2 (ko) |
| BR (1) | BR0210873A (ko) |
| CA (1) | CA2449922C (ko) |
| CY (1) | CY1112600T1 (ko) |
| DE (1) | DE60239134D1 (ko) |
| DK (1) | DK1405638T3 (ko) |
| ES (1) | ES2359719T3 (ko) |
| MX (1) | MXPA04000124A (ko) |
| PL (1) | PL208138B1 (ko) |
| PT (1) | PT1405638E (ko) |
| RU (1) | RU2290929C2 (ko) |
| WO (1) | WO2003006019A1 (ko) |
| ZA (1) | ZA200309632B (ko) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1714965A4 (en) * | 2004-02-09 | 2007-12-19 | Astellas Pharma Inc | COMPOSITION CONTAINING SOLIFENACINE SUCCINATE |
| JPWO2005087231A1 (ja) * | 2004-03-16 | 2008-01-24 | アステラス製薬株式会社 | ソリフェナシン含有組成物 |
| US7820690B2 (en) * | 2004-03-19 | 2010-10-26 | Solvay Pharmaceuticals Gmbh | Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist |
| AU2005226357B2 (en) | 2004-03-25 | 2010-07-01 | Astellas Pharma Inc. | Composition for solid pharmaceutical preparation of solifenacin or salt thereof |
| CN101601673B (zh) * | 2004-03-25 | 2012-07-18 | 安斯泰来制药株式会社 | 用于固体制剂的索非那新或其盐的组合物 |
| US20060035939A1 (en) * | 2004-07-14 | 2006-02-16 | Japan Tobacco Inc. | 3-Aminobenzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity |
| EP1777225A4 (en) | 2004-07-15 | 2009-06-24 | Japan Tobacco Inc | FUSED BENZAMIDE COMPOUND AND INHIBITOR OF VANILLOID RECEPTOR 1 (VR1) ACTIVITY |
| TWI356699B (en) * | 2004-11-10 | 2012-01-21 | Kissei Pharmaceutical | Agent for treating interstitial cystitis and agent |
| EP1832288B1 (en) * | 2004-12-27 | 2012-06-20 | Astellas Pharma Inc. | Stable granular pharmaceutical composition of solifenacin or its salt |
| EP1852117A4 (en) * | 2005-02-25 | 2010-10-27 | Astellas Pharma Inc | PHARMACEUTICAL AGENT COMPRISING SOLIFENACIN |
| JP3701964B1 (ja) * | 2005-03-08 | 2005-10-05 | アステラス製薬株式会社 | キヌクリジン誘導体の新規な塩 |
| US7815939B2 (en) | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
| JP4614084B2 (ja) * | 2005-07-25 | 2011-01-19 | アステラス製薬株式会社 | キヌクリジン誘導体含有医薬組成物 |
| US7906508B2 (en) * | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
| WO2007074916A1 (ja) | 2005-12-28 | 2007-07-05 | Japan Tobacco Inc. | ３，４－ジヒドロベンゾオキサジン化合物及びバニロイド受容体１型（ｖｒ１）活性阻害剤 |
| TWI482629B (zh) * | 2008-07-01 | 2015-05-01 | Tobishi Pharmaceutical Co | 下泌尿道疾病治療劑及下泌尿道症狀改善劑 |
| MD4025C2 (ro) * | 2009-08-25 | 2010-10-31 | Владимир КАРАУШ | Remediu pentru tratamentul prostatitei şi hiperplaziei prostatei |
| EP2818166A1 (en) * | 2013-06-26 | 2014-12-31 | Laboratorios del Dr. Esteve S.A. | Use of sigma receptor ligands for the prevention and treatment of pain associated to interstitial cystitis/bladder pain syndrome (IC/BPS) |
| DE102022104759A1 (de) | 2022-02-28 | 2023-08-31 | SCi Kontor GmbH | Co-Kristall-Screening Verfahren, insbesondere zur Herstellung von Co-Kristallen |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2005012I1 (no) * | 1994-12-28 | 2005-06-06 | Debio Rech Pharma Sa | Triptorelin og farmasoytisk akseptable salter derav |
| EP2246066A1 (en) * | 1997-07-15 | 2010-11-03 | The Regents of the University of Colorado | Use of neurotoxin therapy for treatment of urologic and related disorders |
| CN1224384C (zh) * | 1998-11-05 | 2005-10-26 | 大鹏药品工业株式会社 | 用于治疗排尿紊乱的治疗药物 |
| AR025353A1 (es) * | 1999-08-23 | 2002-11-20 | Lundbeck & Co As H | Tratamiento de la incontinencia urinaria |
-
2002
- 2002-07-08 MX MXPA04000124A patent/MXPA04000124A/es active IP Right Grant
- 2002-07-08 EP EP02741446A patent/EP1405638B1/en not_active Expired - Lifetime
- 2002-07-08 DE DE60239134T patent/DE60239134D1/de not_active Expired - Lifetime
- 2002-07-08 RU RU2004103746/15A patent/RU2290929C2/ru not_active IP Right Cessation
- 2002-07-08 ZA ZA200309632A patent/ZA200309632B/en unknown
- 2002-07-08 KR KR1020047000284A patent/KR100874815B1/ko not_active IP Right Cessation
- 2002-07-08 ES ES02741446T patent/ES2359719T3/es not_active Expired - Lifetime
- 2002-07-08 CN CNB028140303A patent/CN1270708C/zh not_active Expired - Fee Related
- 2002-07-08 JP JP2003511825A patent/JP4174673B2/ja not_active Expired - Fee Related
- 2002-07-08 PT PT02741446T patent/PT1405638E/pt unknown
- 2002-07-08 DK DK02741446.5T patent/DK1405638T3/da active
- 2002-07-08 WO PCT/JP2002/006904 patent/WO2003006019A1/ja active IP Right Grant
- 2002-07-08 CA CA002449922A patent/CA2449922C/en not_active Expired - Fee Related
- 2002-07-08 US US10/479,798 patent/US7335668B2/en not_active Expired - Lifetime
- 2002-07-08 AU AU2002315814A patent/AU2002315814B2/en not_active Ceased
- 2002-07-08 AT AT02741446T patent/ATE497765T1/de active
- 2002-07-08 BR BR0210873-9A patent/BR0210873A/pt not_active IP Right Cessation
- 2002-07-08 PL PL366731A patent/PL208138B1/pl not_active IP Right Cessation
-
2008
- 2008-01-03 US US12/003,908 patent/US20090105298A1/en not_active Abandoned
-
2011
- 2011-03-11 CY CY20111100272T patent/CY1112600T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1405638T3 (da) | 2011-04-18 |
| ES2359719T3 (es) | 2011-05-26 |
| US20090105298A1 (en) | 2009-04-23 |
| EP1405638A4 (en) | 2006-04-12 |
| CA2449922C (en) | 2008-11-25 |
| DE60239134D1 (de) | 2011-03-24 |
| JP4174673B2 (ja) | 2008-11-05 |
| RU2290929C2 (ru) | 2007-01-10 |
| CA2449922A1 (en) | 2003-01-23 |
| PL208138B1 (pl) | 2011-03-31 |
| EP1405638A1 (en) | 2004-04-07 |
| CN1270708C (zh) | 2006-08-23 |
| JPWO2003006019A1 (ja) | 2004-10-28 |
| EP1405638B1 (en) | 2011-02-09 |
| CN1527708A (zh) | 2004-09-08 |
| BR0210873A (pt) | 2004-06-22 |
| ATE497765T1 (de) | 2011-02-15 |
| US20040138252A1 (en) | 2004-07-15 |
| KR100874815B1 (ko) | 2008-12-19 |
| MXPA04000124A (es) | 2004-05-21 |
| PT1405638E (pt) | 2011-04-06 |
| CY1112600T1 (el) | 2016-02-10 |
| WO2003006019A1 (fr) | 2003-01-23 |
| RU2004103746A (ru) | 2005-03-27 |
| KR20040029358A (ko) | 2004-04-06 |
| AU2002315814B2 (en) | 2007-05-31 |
| PL366731A1 (en) | 2005-02-07 |
| US7335668B2 (en) | 2008-02-26 |
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