ZA200306111B - Plant cell having animal-type sugar chain adding function. - Google Patents
Plant cell having animal-type sugar chain adding function. Download PDFInfo
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- ZA200306111B ZA200306111B ZA200306111A ZA200306111A ZA200306111B ZA 200306111 B ZA200306111 B ZA 200306111B ZA 200306111 A ZA200306111 A ZA 200306111A ZA 200306111 A ZA200306111 A ZA 200306111A ZA 200306111 B ZA200306111 B ZA 200306111B
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- South Africa
- Prior art keywords
- sugar chain
- plant
- animal
- plant cell
- cells
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- 210000001672 ovary Anatomy 0.000 description 1
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- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000003375 plant hormone Substances 0.000 description 1
- 238000004161 plant tissue culture Methods 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229940097325 prolactin Drugs 0.000 description 1
- 238000002731 protein assay Methods 0.000 description 1
- 229960000856 protein c Drugs 0.000 description 1
- 108060006633 protein kinase Proteins 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
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- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000003161 ribonuclease inhibitor Substances 0.000 description 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 description 1
- 229960001225 rifampicin Drugs 0.000 description 1
- 239000011833 salt mixture Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000020183 skimmed milk Nutrition 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007974 sodium acetate buffer Substances 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
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- 238000011426 transformation method Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
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- 239000012137 tryptone Substances 0.000 description 1
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- 238000001262 western blot Methods 0.000 description 1
- NLIVDORGVGAOOJ-MAHBNPEESA-M xylene cyanol Chemical compound [Na+].C1=C(C)C(NCC)=CC=C1C(\C=1C(=CC(OS([O-])=O)=CC=1)OS([O-])=O)=C\1C=C(C)\C(=[NH+]/CC)\C=C/1 NLIVDORGVGAOOJ-MAHBNPEESA-M 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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JP2001062704A JP5623683B2 (ja) | 2000-03-22 | 2001-03-06 | 動物型糖鎖付加機能をもつ植物細胞 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200306111B true ZA200306111B (en) | 2004-08-10 |
Family
ID=18921803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ZA200306111A ZA200306111B (en) | 2001-03-06 | 2003-08-07 | Plant cell having animal-type sugar chain adding function. |
Country Status (10)
Country | Link |
---|---|
US (3) | US20050144670A1 (fr) |
EP (2) | EP2078455A1 (fr) |
CN (2) | CN1541059A (fr) |
AU (1) | AU2002236234B2 (fr) |
BR (1) | BR0207857A (fr) |
CA (1) | CA2438375C (fr) |
IL (2) | IL157736A0 (fr) |
MX (1) | MXPA03008001A (fr) |
WO (1) | WO2002070672A2 (fr) |
ZA (1) | ZA200306111B (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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BR9917026B1 (pt) | 1998-12-09 | 2010-10-19 | método para fabricar glicoproteìnas tendo glicosilação do tipo humano. | |
CA2389217C (fr) * | 1999-10-26 | 2016-12-06 | Plant Research International B.V. | Glycosylation du type mammifere sur des plantes |
US7632983B2 (en) | 2000-07-31 | 2009-12-15 | Biolex Therapeutics, Inc. | Expression of monoclonal antibodies in duckweed |
DK1356068T3 (en) | 2001-01-19 | 2015-02-16 | Phyton Holdings Llc | PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN FOR USING A PLANT CELL |
EP2078455A1 (fr) * | 2001-03-06 | 2009-07-15 | The Dow Chemical Company | Cellule végétale disposant d'une fonction d'ajout de chaîne de sucre de type animal |
NZ546945A (en) | 2002-03-19 | 2008-04-30 | Plant Res Int Bv | A plant host cell system for the expression of human GnTIII |
WO2003078637A2 (fr) * | 2002-03-19 | 2003-09-25 | Plant Research International B.V. | Optimisation du traitement du glycane chez les plantes |
AR042145A1 (es) | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
NZ549537A (en) | 2004-02-11 | 2009-09-25 | Biolex Therapeutics Inc | Expression of plasminogen and microplasminogen in duckweed |
WO2006071645A2 (fr) | 2004-12-23 | 2006-07-06 | Nonomura Arthur M | Compositions et procedes pour limiter la transpiration vegetale |
US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
US7884264B2 (en) * | 2006-01-17 | 2011-02-08 | Biolex Therapeutics, Inc. | Compositions and methods for inhibition of fucosyltransferase and xylosyltransferase expression in duckweed plants |
JP5485869B2 (ja) | 2007-04-17 | 2014-05-07 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 非哺乳動物グリコシルトランスフェラーゼの発現による植物における哺乳動物型グリコシル化反応 |
EP2782990B1 (fr) | 2011-11-21 | 2020-10-07 | Innovation Hammer LLC | Procédé de culture de plantes utilisant des billes de silicate et une photoprotection par utilisation de glycopyranosides exogènes |
US9828299B2 (en) | 2012-05-21 | 2017-11-28 | Innovation Hammer, Llc | Methods for rendering micellar coordination complexes safe for the treatment of plants and formulations for same |
KR101606918B1 (ko) * | 2014-08-04 | 2016-03-28 | 경상대학교산학협력단 | 인간화 저-만노스형 엔-당질 합성 식물 및 이의 용도 |
JP6523748B2 (ja) * | 2015-04-01 | 2019-06-05 | シスメックス株式会社 | 糖タンパク質の製造方法および糖タンパク質 |
JP7313150B2 (ja) | 2016-04-29 | 2023-07-24 | イノベーション・ハマー・エルエルシー | グリカンコンポジット配合物で光合成生物を処理し、収穫物の品質及び量を高めるための配合物及び方法 |
CN110317799A (zh) * | 2019-07-18 | 2019-10-11 | 江南大学 | 一种人源岩藻糖转移酶8的原核表达方法及其产品 |
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US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US4956282A (en) * | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
EP0292435B1 (fr) | 1987-05-20 | 1995-07-26 | Ciba-Geigy Ag | Plantes de zea mays et plantes transgéniques de zea mays régénérées de protoplastes ou de cellules dérivées de protoplastes |
EP0332581B1 (fr) | 1988-03-08 | 1996-12-11 | Ciba-Geigy Ag | Régénération de plantes graminées fertiles de la sous-famille des pooideae à partir de protoplastes |
US5202422A (en) * | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
US5959177A (en) * | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US5180674A (en) * | 1990-04-16 | 1993-01-19 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
US5610042A (en) | 1991-10-07 | 1997-03-11 | Ciba-Geigy Corporation | Methods for stable transformation of wheat |
US5294593A (en) * | 1992-05-14 | 1994-03-15 | Cornell Research Foundation, Inc. | Inducing dormancy in non dormant seeds |
US5874271A (en) * | 1992-08-21 | 1999-02-23 | Takara Shuzo Co., Ltd. | Human glycosyltransferase gene, compounds and method for inhibiting cancerous metastasis |
EP0785988A1 (fr) * | 1993-07-15 | 1997-07-30 | Neose Pharmaceuticals, Inc | Procede de synthese de compositions de saccharide |
US5939288A (en) * | 1995-06-07 | 1999-08-17 | Iowa State University Research Foundation, Inc. | Plant secretory signal peptides and nectarins |
FR2736930B1 (fr) * | 1995-07-17 | 1997-09-19 | Biocem | Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines |
JP3726355B2 (ja) | 1996-06-21 | 2005-12-14 | 東洋紡績株式会社 | ヒト由来α1→6フコシルトランスフェラーゼ |
EP0816503B1 (fr) * | 1996-01-24 | 2006-07-05 | Toyo Boseki Kabushiki Kaisha | Alpha-1-6 fucosyltransferases |
JP3642361B2 (ja) | 1996-01-24 | 2005-04-27 | 東洋紡績株式会社 | ブタ由来α1→6フコシルトランスフェラーゼ |
JPH104969A (ja) | 1996-06-24 | 1998-01-13 | Toyobo Co Ltd | α−1,6−フコシルトランスフェラーゼ遺伝子 |
JP3785745B2 (ja) | 1996-07-22 | 2006-06-14 | 東洋紡績株式会社 | ヒト由来α−1,6−フコシルトランスフェラーゼ遺伝子 |
DE69738177T2 (de) * | 1996-08-02 | 2008-07-03 | The Austin Research Institute, Heidelberg | Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren |
JP4003093B2 (ja) * | 1997-07-29 | 2007-11-07 | 東洋紡績株式会社 | 糖類の製造方法 |
DE19754622A1 (de) * | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
US5955282A (en) * | 1998-04-03 | 1999-09-21 | Incyte Pharmaceuticals, Inc. | Human galactosyltransferases |
ATE458007T1 (de) * | 1998-04-20 | 2010-03-15 | Glycart Biotechnology Ag | Glykosylierungs-engineering von antikörpern zur verbesserung der antikörperabhängigen zellvermittelten zytotoxizität |
US6558934B1 (en) * | 1998-07-17 | 2003-05-06 | Glycozm Aps | UDP-galactose: β-N-acetyl-glucosamine β-1,4-galactosyl-transferase, β4Gal-T2 |
BR9917026B1 (pt) * | 1998-12-09 | 2010-10-19 | método para fabricar glicoproteìnas tendo glicosilação do tipo humano. | |
JP2000245470A (ja) * | 1999-02-26 | 2000-09-12 | Noda Inst For Scient Res | 植物細胞間液による外来ポリペプチドの製造方法 |
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US20020174453A1 (en) * | 2001-04-18 | 2002-11-21 | Henry Daniell | Production of antibodies in transgenic plastids |
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TW519716B (en) * | 2000-12-19 | 2003-02-01 | Tokyo Electron Ltd | Wafer bias drive for a plasma source |
DK1356068T3 (en) * | 2001-01-19 | 2015-02-16 | Phyton Holdings Llc | PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN FOR USING A PLANT CELL |
EP2078455A1 (fr) * | 2001-03-06 | 2009-07-15 | The Dow Chemical Company | Cellule végétale disposant d'une fonction d'ajout de chaîne de sucre de type animal |
WO2003078637A2 (fr) * | 2002-03-19 | 2003-09-25 | Plant Research International B.V. | Optimisation du traitement du glycane chez les plantes |
NZ546945A (en) * | 2002-03-19 | 2008-04-30 | Plant Res Int Bv | A plant host cell system for the expression of human GnTIII |
AR042145A1 (es) * | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
MX2007011801A (es) * | 2005-03-24 | 2008-02-19 | Neose Technologies Inc | Expresion de glicosiltransferasas eucarioticas activas, solubles en organismos procarioticos. |
US20070214273A1 (en) * | 2006-03-10 | 2007-09-13 | Pronto Networks | Across firewall communication system and method |
JP5485869B2 (ja) * | 2007-04-17 | 2014-05-07 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 非哺乳動物グリコシルトランスフェラーゼの発現による植物における哺乳動物型グリコシル化反応 |
-
2002
- 2002-03-06 EP EP08020953A patent/EP2078455A1/fr not_active Ceased
- 2002-03-06 US US10/467,101 patent/US20050144670A1/en not_active Abandoned
- 2002-03-06 CN CNA02805959XA patent/CN1541059A/zh active Pending
- 2002-03-06 WO PCT/JP2002/002091 patent/WO2002070672A2/fr active Application Filing
- 2002-03-06 EP EP02702772A patent/EP1367881A2/fr not_active Ceased
- 2002-03-06 MX MXPA03008001A patent/MXPA03008001A/es active IP Right Grant
- 2002-03-06 CN CN200910146674A patent/CN101781635A/zh active Pending
- 2002-03-06 AU AU2002236234A patent/AU2002236234B2/en not_active Ceased
- 2002-03-06 BR BR0207857-0A patent/BR0207857A/pt not_active Application Discontinuation
- 2002-03-06 IL IL15773602A patent/IL157736A0/xx unknown
- 2002-03-06 CA CA2438375A patent/CA2438375C/fr not_active Expired - Fee Related
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2003
- 2003-08-07 ZA ZA200306111A patent/ZA200306111B/en unknown
- 2003-09-03 IL IL157736A patent/IL157736A/en not_active IP Right Cessation
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2007
- 2007-01-04 US US11/649,720 patent/US20070214519A1/en not_active Abandoned
-
2016
- 2016-11-21 US US15/358,005 patent/US20170275599A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2078455A1 (fr) | 2009-07-15 |
IL157736A0 (en) | 2004-03-28 |
IL157736A (en) | 2014-04-30 |
US20170275599A1 (en) | 2017-09-28 |
EP1367881A2 (fr) | 2003-12-10 |
WO2002070672A3 (fr) | 2003-07-03 |
CA2438375C (fr) | 2014-07-15 |
US20070214519A1 (en) | 2007-09-13 |
BR0207857A (pt) | 2004-03-23 |
CN1541059A (zh) | 2004-10-27 |
CA2438375A1 (fr) | 2002-09-12 |
AU2002236234B2 (en) | 2007-12-20 |
MXPA03008001A (es) | 2004-10-15 |
CN101781635A (zh) | 2010-07-21 |
US20050144670A1 (en) | 2005-06-30 |
WO2002070672A2 (fr) | 2002-09-12 |
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