ZA200305184B - Sequences upstream of the CARP gene, vectors containing them and uses thereof. - Google Patents

Sequences upstream of the CARP gene, vectors containing them and uses thereof. Download PDF

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Publication number
ZA200305184B
ZA200305184B ZA200305184A ZA200305184A ZA200305184B ZA 200305184 B ZA200305184 B ZA 200305184B ZA 200305184 A ZA200305184 A ZA 200305184A ZA 200305184 A ZA200305184 A ZA 200305184A ZA 200305184 B ZA200305184 B ZA 200305184B
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ZA
South Africa
Prior art keywords
polynucleotide
composition
vector
cardiac
substance
Prior art date
Application number
ZA200305184A
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English (en)
Inventor
Bertrand Schwartz
Patrick Benoit
Ju Chen
Didier Branellec
Kenneth Chien
Original Assignee
Gencell S A The Regents Of The
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gencell S A The Regents Of The filed Critical Gencell S A The Regents Of The
Publication of ZA200305184B publication Critical patent/ZA200305184B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA200305184A 2000-12-07 2003-07-03 Sequences upstream of the CARP gene, vectors containing them and uses thereof. ZA200305184B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25158200P 2000-12-07 2000-12-07

Publications (1)

Publication Number Publication Date
ZA200305184B true ZA200305184B (en) 2004-10-04

Family

ID=22952571

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200305184A ZA200305184B (en) 2000-12-07 2003-07-03 Sequences upstream of the CARP gene, vectors containing them and uses thereof.

Country Status (18)

Country Link
US (3) US7193075B2 (fr)
EP (1) EP1358208A2 (fr)
JP (1) JP2004519222A (fr)
KR (1) KR20030090609A (fr)
CN (1) CN1483040A (fr)
AU (2) AU2002226400B2 (fr)
BR (1) BR0116014A (fr)
CA (1) CA2431193A1 (fr)
CZ (1) CZ20031569A3 (fr)
FI (1) FI20030851A (fr)
IL (1) IL156137A0 (fr)
MX (1) MXPA03005039A (fr)
NO (1) NO20032584L (fr)
NZ (1) NZ526408A (fr)
PL (1) PL365314A1 (fr)
RU (1) RU2283865C2 (fr)
WO (1) WO2002046220A2 (fr)
ZA (1) ZA200305184B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0410844A (pt) * 2003-06-05 2006-06-27 Centelion fator de crescimento de fibroblasto de codificação de plasmìdeo para o tratamento de defeitos angiogênicos associados com hipercolesterolemia ou diabetes
RU2499599C2 (ru) 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
WO2010062518A1 (fr) * 2008-10-28 2010-06-03 Pioneer Hi-Bred International, Inc. Protéines répresseurs sensibles à la sulfonylurée
AU2010210605B2 (en) * 2009-02-04 2015-08-13 Board Of Regents, The University Of Texas System Dual targeting of miR-208 and miR-499 in the treatment of cardiac disorders
RU2497529C2 (ru) * 2011-11-08 2013-11-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ стимуляции регенеративных процессов в ишемизированных тканях
CN105779457B (zh) * 2016-05-31 2019-02-12 北京大学 心肌细胞特异启动子及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE294874T1 (de) * 1998-09-11 2005-05-15 Univ California Rekombinante adenovirus für gewebespezifische genexpression ins herz
US6033642A (en) * 1999-03-29 2000-03-07 Starmet Corporation Method for producing silicon tetrafluoride from uranium oxyfluoride

Also Published As

Publication number Publication date
US20030039984A1 (en) 2003-02-27
AU2640002A (en) 2002-06-18
NO20032584D0 (no) 2003-06-06
NZ526408A (en) 2005-07-29
US20070150971A1 (en) 2007-06-28
KR20030090609A (ko) 2003-11-28
CZ20031569A3 (cs) 2003-11-12
US20060110362A1 (en) 2006-05-25
WO2002046220A3 (fr) 2003-09-04
BR0116014A (pt) 2003-10-21
WO2002046220A2 (fr) 2002-06-13
RU2283865C2 (ru) 2006-09-20
IL156137A0 (en) 2003-12-23
JP2004519222A (ja) 2004-07-02
CA2431193A1 (fr) 2002-06-13
AU2002226400B2 (en) 2006-11-02
CN1483040A (zh) 2004-03-17
US7193075B2 (en) 2007-03-20
PL365314A1 (en) 2004-12-27
RU2003120081A (ru) 2005-01-27
MXPA03005039A (es) 2004-08-02
EP1358208A2 (fr) 2003-11-05
NO20032584L (no) 2003-08-05
FI20030851A (fi) 2003-06-06
WO2002046220A9 (fr) 2007-11-08

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