ZA200209410B - Pyridine-2-yl-aminoalkyl carbonyl glycyl-beta-alanine and derivatives thereof. - Google Patents

Pyridine-2-yl-aminoalkyl carbonyl glycyl-beta-alanine and derivatives thereof. Download PDF

Info

Publication number
ZA200209410B
ZA200209410B ZA200209410A ZA200209410A ZA200209410B ZA 200209410 B ZA200209410 B ZA 200209410B ZA 200209410 A ZA200209410 A ZA 200209410A ZA 200209410 A ZA200209410 A ZA 200209410A ZA 200209410 B ZA200209410 B ZA 200209410B
Authority
ZA
South Africa
Prior art keywords
formula
pyridin
ylamino
ethanoylamino
acid
Prior art date
Application number
ZA200209410A
Other languages
English (en)
Inventor
Guenter Hoelzemann
Simon Goodman
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200209410B publication Critical patent/ZA200209410B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200209410A 2000-06-13 2002-11-19 Pyridine-2-yl-aminoalkyl carbonyl glycyl-beta-alanine and derivatives thereof. ZA200209410B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10028402A DE10028402A1 (de) 2000-06-13 2000-06-13 Pyridin-2-yl-aminoalkycarbonylglycyl-beta-alanin und Derivate

Publications (1)

Publication Number Publication Date
ZA200209410B true ZA200209410B (en) 2004-02-19

Family

ID=7645128

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200209410A ZA200209410B (en) 2000-06-13 2002-11-19 Pyridine-2-yl-aminoalkyl carbonyl glycyl-beta-alanine and derivatives thereof.

Country Status (18)

Country Link
US (1) US20030171304A1 (cs)
EP (1) EP1290010A1 (cs)
JP (1) JP2004503562A (cs)
KR (1) KR20030022145A (cs)
CN (1) CN1436196A (cs)
AR (1) AR028714A1 (cs)
AU (1) AU6606301A (cs)
BR (1) BR0111555A (cs)
CA (1) CA2414000A1 (cs)
CZ (1) CZ20023952A3 (cs)
DE (1) DE10028402A1 (cs)
HU (1) HUP0303716A2 (cs)
MX (1) MXPA02012411A (cs)
NO (1) NO20025968D0 (cs)
PL (1) PL358671A1 (cs)
SK (1) SK17112002A3 (cs)
WO (1) WO2001096365A1 (cs)
ZA (1) ZA200209410B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
EE200100651A (et) 1999-06-01 2003-02-17 Biogen, Inc. VLA-1 blokeeriv monoklonaalne antikeha ja tema kasutamine põletiku raviks
MXPA03009390A (es) 2001-04-13 2004-01-29 Biogen Inc Anticuerpos para integrina vla-1.
US7176322B2 (en) 2002-05-23 2007-02-13 Amgen Inc. Calcium receptor modulating agents
US6908935B2 (en) 2002-05-23 2005-06-21 Amgen Inc. Calcium receptor modulating agents
MXPA06010756A (es) 2004-03-24 2006-12-15 Jerini Ag Nuevos compuestos para la inhibicion de la angiogenesis y su uso.
US20090196912A1 (en) * 2004-07-30 2009-08-06 Gpc Botech Ag Pyridinylamines
PL2034830T3 (pl) 2006-05-25 2015-04-30 Biogen Ma Inc Przeciwciało anty-VLA-1 do leczenia udaru
WO2010057922A1 (en) * 2008-11-24 2010-05-27 Basf Se Curable composition comprising a thermolatent base
CN104271122A (zh) 2012-02-16 2015-01-07 桑塔鲁斯股份有限公司 抗vla1(cd49a)抗体药物组合物
MY208467A (en) * 2017-11-01 2025-05-11 Arrowhead Pharmaceuticals Inc Integrin ligands and uses thereof
CA3213968A1 (en) 2021-04-08 2022-10-13 Arrowhead Pharmaceuticals, Inc. Rnai agents for inhibiting expression of receptor for advanced glycation end-products, compositions thereof, and methods of use
WO2025152967A1 (zh) * 2024-01-15 2025-07-24 武汉人福创新药物研发中心有限公司 靶向αvβ6的化合物及其用途
WO2025152969A1 (zh) * 2024-01-15 2025-07-24 武汉人福创新药物研发中心有限公司 靶向化合物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024124A1 (en) * 1995-12-29 1997-07-10 Smithkline Beecham Corporation Vitronectin receptor antagonists

Also Published As

Publication number Publication date
EP1290010A1 (de) 2003-03-12
NO20025968L (no) 2002-12-12
CZ20023952A3 (cs) 2003-03-12
DE10028402A1 (de) 2001-12-20
US20030171304A1 (en) 2003-09-11
BR0111555A (pt) 2003-07-08
PL358671A1 (en) 2004-08-09
AU6606301A (en) 2001-12-24
CA2414000A1 (en) 2002-12-03
HUP0303716A2 (hu) 2004-03-01
KR20030022145A (ko) 2003-03-15
CN1436196A (zh) 2003-08-13
WO2001096365A1 (de) 2001-12-20
NO20025968D0 (no) 2002-12-12
SK17112002A3 (sk) 2003-04-01
MXPA02012411A (es) 2003-04-25
AR028714A1 (es) 2003-05-21
JP2004503562A (ja) 2004-02-05

Similar Documents

Publication Publication Date Title
EP1377540B1 (en) Inhibitors of integrin alpha-v-beta-6
AU2002254900A1 (en) Inhibitors of integrin AlphavBeta6
US20030171304A1 (en) Pyridine-2-yl-aminoalkyl carbonyl glycyl-$g(b)-alanine and derivatives thereof
US6576637B1 (en) β-alanine derivatives
US7138417B2 (en) Inhibitors of integrin αvβ6
JP4216071B2 (ja) インテグリン阻害剤としての尿素およびウレタン誘導体
US20040010023A1 (en) Biphenyl derivatives and the use thereof as integrin inhibitors
KR20030090739A (ko) αｖβ6 인테그린의 리간드
AU6155100A (en) Diacylhydrazine derivatives
US20040157902A1 (en) Integrin antagonists
KR20030022419A (ko) 비페닐 유도체, 및 인테그린 저해제로서의 그의 용도