ZA200109860B - Aminoalkyl substituted (benzodioxan, benzufuran or benzopyran) derivatives. - Google Patents

Aminoalkyl substituted (benzodioxan, benzufuran or benzopyran) derivatives.

Info

Publication number
ZA200109860B
ZA200109860B ZA200109860A ZA200109860A ZA200109860B ZA 200109860 B ZA200109860 B ZA 200109860B ZA 200109860 A ZA200109860 A ZA 200109860A ZA 200109860 A ZA200109860 A ZA 200109860A ZA 200109860 B ZA200109860 B ZA 200109860B
Authority
ZA
South Africa
Prior art keywords
benzufuran
benzodioxan
benzopyran
derivatives
aminoalkyl substituted
Prior art date
Application number
ZA200109860A
Other languages
English (en)
Inventor
Kristof Van Emelen
Marcel Frans Leopold De Bruyn
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA200109860B publication Critical patent/ZA200109860B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
ZA200109860A 1999-06-02 2001-11-29 Aminoalkyl substituted (benzodioxan, benzufuran or benzopyran) derivatives. ZA200109860B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201747 1999-06-02

Publications (1)

Publication Number Publication Date
ZA200109860B true ZA200109860B (en) 2003-05-28

Family

ID=8240260

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109860A ZA200109860B (en) 1999-06-02 2001-11-29 Aminoalkyl substituted (benzodioxan, benzufuran or benzopyran) derivatives.

Country Status (33)

Country Link
US (2) US6864273B1 (ko)
EP (1) EP1187829B1 (ko)
JP (1) JP2003501427A (ko)
KR (1) KR100699512B1 (ko)
CN (1) CN1150191C (ko)
AR (1) AR033334A1 (ko)
AT (1) ATE256125T1 (ko)
AU (1) AU773773B2 (ko)
BG (1) BG65269B1 (ko)
BR (1) BR0011237A (ko)
CA (1) CA2374902C (ko)
CZ (1) CZ20014177A3 (ko)
DE (1) DE60007124T2 (ko)
DK (1) DK1187829T3 (ko)
EA (1) EA004645B1 (ko)
EE (1) EE04780B1 (ko)
ES (1) ES2212774T3 (ko)
HR (1) HRP20010868A2 (ko)
HU (1) HUP0201404A3 (ko)
IL (2) IL146840A0 (ko)
MX (1) MXPA01012330A (ko)
MY (1) MY120618A (ko)
NO (1) NO319953B1 (ko)
NZ (1) NZ514993A (ko)
PL (1) PL198552B1 (ko)
PT (1) PT1187829E (ko)
SI (1) SI1187829T1 (ko)
SK (1) SK285619B6 (ko)
TR (1) TR200103430T2 (ko)
TW (1) TWI289559B (ko)
UA (1) UA73122C2 (ko)
WO (1) WO2000075136A1 (ko)
ZA (1) ZA200109860B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20014167A3 (cs) 1999-06-02 2002-06-12 Janssen Pharmaceutica N. V. Pyrrolidinylem, piperidinylem nebo homopiperidinylem substituované deriváty benzodioxanu, benzofuranu nebo benzopyranu
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
SI1493441T1 (sl) * 2002-04-08 2011-12-30 Zeria Pharm Co Ltd Terapevtsko sredstvo za motnjo prilagoditve Ĺľelodca na zauĹľito prehrano
WO2006089053A2 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
EP2776405A1 (en) 2011-11-11 2014-09-17 Pfizer Inc 2-thiopyrimidinones
WO2016178113A1 (en) 2015-05-05 2016-11-10 Pfizer Inc. 2-thiopyrimidinones

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (ko) 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
DE69433401T2 (de) 1993-08-19 2004-09-16 Janssen Pharmaceutica N.V. Gefässverengende dihydrobenzopyranderivate
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
CZ20014167A3 (cs) * 1999-06-02 2002-06-12 Janssen Pharmaceutica N. V. Pyrrolidinylem, piperidinylem nebo homopiperidinylem substituované deriváty benzodioxanu, benzofuranu nebo benzopyranu
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
EE04780B1 (et) 2007-02-15
IL146840A0 (en) 2002-07-25
NO319953B1 (no) 2005-10-03
SK17032001A3 (sk) 2002-07-02
DK1187829T3 (da) 2004-04-13
TR200103430T2 (tr) 2002-06-21
EA200101236A1 (ru) 2002-08-29
EP1187829B1 (en) 2003-12-10
US7273862B2 (en) 2007-09-25
DE60007124D1 (de) 2004-01-22
US6864273B1 (en) 2005-03-08
CZ20014177A3 (cs) 2002-05-15
KR20010110806A (ko) 2001-12-13
PT1187829E (pt) 2004-04-30
UA73122C2 (en) 2005-06-15
NO20015903D0 (no) 2001-12-03
MY120618A (en) 2005-11-30
DE60007124T2 (de) 2004-09-23
HUP0201404A2 (en) 2002-08-28
AU773773B2 (en) 2004-06-03
CA2374902C (en) 2009-09-15
NZ514993A (en) 2003-05-30
EP1187829A1 (en) 2002-03-20
EE200100639A (et) 2003-02-17
ES2212774T3 (es) 2004-08-01
IL146840A (en) 2006-12-10
US20050096378A1 (en) 2005-05-05
MXPA01012330A (es) 2002-07-30
JP2003501427A (ja) 2003-01-14
TWI289559B (en) 2007-11-11
SK285619B6 (sk) 2007-05-03
WO2000075136A1 (en) 2000-12-14
BG65269B1 (bg) 2007-11-30
SI1187829T1 (en) 2004-04-30
BR0011237A (pt) 2002-03-05
AU5525600A (en) 2000-12-28
EA004645B1 (ru) 2004-06-24
KR100699512B1 (ko) 2007-03-26
AR033334A1 (es) 2003-12-17
HUP0201404A3 (en) 2005-02-28
PL352112A1 (en) 2003-07-28
BG106156A (en) 2002-05-31
CN1150191C (zh) 2004-05-19
CN1353707A (zh) 2002-06-12
HRP20010868A2 (en) 2003-04-30
CA2374902A1 (en) 2000-12-14
ATE256125T1 (de) 2003-12-15
PL198552B1 (pl) 2008-06-30
NO20015903L (no) 2001-12-03

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