ZA200109343B - Dibenzoazulene derivatives for treating thrombosis, osteoporosis, arteriosclerosis. - Google Patents
Dibenzoazulene derivatives for treating thrombosis, osteoporosis, arteriosclerosis.Info
- Publication number
- ZA200109343B ZA200109343B ZA200109343A ZA200109343A ZA200109343B ZA 200109343 B ZA200109343 B ZA 200109343B ZA 200109343 A ZA200109343 A ZA 200109343A ZA 200109343 A ZA200109343 A ZA 200109343A ZA 200109343 B ZA200109343 B ZA 200109343B
- Authority
- ZA
- South Africa
- Prior art keywords
- arteriosclerosis
- osteoporosis
- treating thrombosis
- dibenzoazulene derivatives
- dibenzoazulene
- Prior art date
Links
- 206010003210 Arteriosclerosis Diseases 0.000 title 1
- 208000001132 Osteoporosis Diseases 0.000 title 1
- 208000007536 Thrombosis Diseases 0.000 title 1
- 208000011775 arteriosclerosis disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19916837A DE19916837A1 (de) | 1999-04-14 | 1999-04-14 | Dibenzoazulenderivate |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200109343B true ZA200109343B (en) | 2003-04-30 |
Family
ID=7904536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200109343A ZA200109343B (en) | 1999-04-14 | 2001-11-13 | Dibenzoazulene derivatives for treating thrombosis, osteoporosis, arteriosclerosis. |
Country Status (19)
Country | Link |
---|---|
US (1) | US6521646B1 (xx) |
EP (1) | EP1169306A1 (xx) |
JP (1) | JP2002542231A (xx) |
KR (1) | KR20010102570A (xx) |
CN (1) | CN1345312A (xx) |
AR (1) | AR023496A1 (xx) |
AU (1) | AU3817400A (xx) |
BR (1) | BR0009690A (xx) |
CA (1) | CA2367359A1 (xx) |
CZ (1) | CZ20013704A3 (xx) |
DE (1) | DE19916837A1 (xx) |
HU (1) | HUP0200643A3 (xx) |
MX (1) | MXPA01010294A (xx) |
NO (1) | NO20014976L (xx) |
PL (1) | PL350354A1 (xx) |
RU (1) | RU2001129708A (xx) |
SK (1) | SK14342001A3 (xx) |
WO (1) | WO2000063178A1 (xx) |
ZA (1) | ZA200109343B (xx) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2806082B1 (fr) * | 2000-03-07 | 2002-05-17 | Adir | Nouveaux composes bicycliques antagonistes des recepteurs de la vitronectine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP4964389B2 (ja) * | 2000-06-30 | 2012-06-27 | ダウ グローバル テクノロジーズ エルエルシー | 多環式、縮合環化合物、金属錯体及び重合方法 |
US20050107350A1 (en) * | 2003-08-22 | 2005-05-19 | Pharmacia Corporation | Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith |
KR101224368B1 (ko) | 2004-06-04 | 2013-01-22 | 더 스크립스 리서치 인스티튜트 | 혈관신생 질환 치료용 조성물 및 방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3795709A (en) * | 1968-02-07 | 1974-03-05 | Sandoz Ag | Benzobenzazulenes |
ES2148742T3 (es) * | 1995-03-09 | 2000-10-16 | Ortho Pharma Corp | Dibenz(a,f)azulenos sustituidos y procedimientos de preparacion. |
EP0910563B1 (en) * | 1995-06-29 | 2003-05-02 | Smithkline Beecham Corporation | Integrin receptor antagonists |
EA002271B1 (ru) * | 1996-03-20 | 2002-02-28 | Хехст Марион Руссель | ТРИЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ, ОБЛАДАЮЩИЕ АКТИВНОСТЬЮ В ОТНОШЕНИИ ИНТЕГРИНОВ, В ЧАСТНОСТИ В ОТНОШЕНИИ ИНТЕГРИНА АЛЬФАvБЕТА 3, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ, ИСПОЛЬЗУЕМЫЕ В ЭТОМ СПОСОБЕ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ МЕДИКАМЕНТОВ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ |
CO4920232A1 (es) * | 1997-01-08 | 2000-05-29 | Smithkline Beecham Corp | Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin |
-
1999
- 1999-04-14 DE DE19916837A patent/DE19916837A1/de not_active Withdrawn
-
2000
- 2000-04-01 RU RU2001129708/04A patent/RU2001129708A/ru unknown
- 2000-04-01 CA CA002367359A patent/CA2367359A1/en not_active Abandoned
- 2000-04-01 AU AU38174/00A patent/AU3817400A/en not_active Abandoned
- 2000-04-01 JP JP2000612271A patent/JP2002542231A/ja active Pending
- 2000-04-01 PL PL00350354A patent/PL350354A1/xx unknown
- 2000-04-01 WO PCT/EP2000/002925 patent/WO2000063178A1/de not_active Application Discontinuation
- 2000-04-01 HU HU0200643A patent/HUP0200643A3/hu unknown
- 2000-04-01 KR KR1020017011575A patent/KR20010102570A/ko not_active Application Discontinuation
- 2000-04-01 US US09/958,812 patent/US6521646B1/en not_active Expired - Fee Related
- 2000-04-01 CZ CZ20013704A patent/CZ20013704A3/cs unknown
- 2000-04-01 MX MXPA01010294A patent/MXPA01010294A/es unknown
- 2000-04-01 BR BR0009690-3A patent/BR0009690A/pt not_active Application Discontinuation
- 2000-04-01 EP EP00917037A patent/EP1169306A1/de not_active Withdrawn
- 2000-04-01 CN CN00805748A patent/CN1345312A/zh active Pending
- 2000-04-01 SK SK1434-2001A patent/SK14342001A3/sk unknown
- 2000-04-14 AR ARP000101738A patent/AR023496A1/es unknown
-
2001
- 2001-10-12 NO NO20014976A patent/NO20014976L/no not_active Application Discontinuation
- 2001-11-13 ZA ZA200109343A patent/ZA200109343B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0200643A3 (en) | 2003-10-28 |
HUP0200643A2 (hu) | 2002-07-29 |
MXPA01010294A (es) | 2002-05-06 |
CZ20013704A3 (cs) | 2002-02-13 |
US6521646B1 (en) | 2003-02-18 |
EP1169306A1 (de) | 2002-01-09 |
NO20014976D0 (no) | 2001-10-12 |
WO2000063178A1 (de) | 2000-10-26 |
DE19916837A1 (de) | 2000-10-19 |
SK14342001A3 (sk) | 2002-04-04 |
NO20014976L (no) | 2001-10-12 |
AR023496A1 (es) | 2002-09-04 |
BR0009690A (pt) | 2002-01-08 |
JP2002542231A (ja) | 2002-12-10 |
AU3817400A (en) | 2000-11-02 |
PL350354A1 (en) | 2002-12-02 |
CA2367359A1 (en) | 2000-10-26 |
RU2001129708A (ru) | 2004-02-27 |
CN1345312A (zh) | 2002-04-17 |
KR20010102570A (ko) | 2001-11-15 |
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