ZA200108915B - Method of removing N-terminal alanine residues from polypeptides with aeromonas aminopeptidase - Google Patents

Method of removing N-terminal alanine residues from polypeptides with aeromonas aminopeptidase

Info

Publication number
ZA200108915B
ZA200108915B ZA200108915A ZA200108915A ZA200108915B ZA 200108915 B ZA200108915 B ZA 200108915B ZA 200108915 A ZA200108915 A ZA 200108915A ZA 200108915 A ZA200108915 A ZA 200108915A ZA 200108915 B ZA200108915 B ZA 200108915B
Authority
ZA
South Africa
Prior art keywords
polypeptides
alanine residues
terminal alanine
aeromonas aminopeptidase
aeromonas
Prior art date
Application number
ZA200108915A
Other languages
English (en)
Inventor
Jacob S Tou
Douglas W Taylor
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of ZA200108915B publication Critical patent/ZA200108915B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200108915A 1999-04-30 2001-01-29 Method of removing N-terminal alanine residues from polypeptides with aeromonas aminopeptidase ZA200108915B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13206299P 1999-04-30 1999-04-30

Publications (1)

Publication Number Publication Date
ZA200108915B true ZA200108915B (en) 2006-04-26

Family

ID=22452276

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200108915A ZA200108915B (en) 1999-04-30 2001-01-29 Method of removing N-terminal alanine residues from polypeptides with aeromonas aminopeptidase

Country Status (14)

Country Link
EP (1) EP1173572B1 (de)
JP (1) JP2002542835A (de)
KR (1) KR20020011399A (de)
CN (1) CN1353755A (de)
AR (1) AR025156A1 (de)
AT (1) ATE352622T1 (de)
AU (1) AU768111B2 (de)
BR (1) BR0010187A (de)
CA (1) CA2370113A1 (de)
DE (1) DE60033141T2 (de)
ES (1) ES2280211T3 (de)
MX (1) MXPA01011057A (de)
WO (1) WO2000066761A2 (de)
ZA (1) ZA200108915B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743600B1 (en) * 1999-04-30 2004-06-01 Monsanto Technologies Llc Method of removing N-terminal alanine residues from polypeptides with Aeromonas aminopeptidase
PL206286B1 (pl) * 2001-09-13 2010-07-30 Genentech Incgenentech Inc Komórka Gram-ujemnej bakterii, sposób wytwarzania heterologicznego peptydu, sposób zapobiegania odcinaniu N-końcowego aminokwasu, sposób odcinania N-końcowego aminokwasu i sposób wytwarzania skróconego polipeptydu
CN105319207A (zh) * 2014-08-01 2016-02-10 上海梅山钢铁股份有限公司 检测电镀锡前湿平整钢板清洗效果的测试液及检测方法
KR101795918B1 (ko) 2015-07-24 2017-11-10 주식회사 포스코 내시효성 및 소부경화성이 우수한 용융아연도금강판, 합금화 용융아연도금강판 및 그 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763215A (en) * 1984-08-16 1998-06-09 Bio-Technology General Corporation Method of removing N-terminal amino acid residues from eucaryotic polypeptide analogs and polypeptides produced thereby

Also Published As

Publication number Publication date
AU4641500A (en) 2000-11-17
CN1353755A (zh) 2002-06-12
JP2002542835A (ja) 2002-12-17
WO2000066761A3 (en) 2001-03-15
AR025156A1 (es) 2002-11-13
ATE352622T1 (de) 2007-02-15
CA2370113A1 (en) 2000-11-09
WO2000066761A2 (en) 2000-11-09
EP1173572A2 (de) 2002-01-23
EP1173572B1 (de) 2007-01-24
ES2280211T3 (es) 2007-09-16
KR20020011399A (ko) 2002-02-08
AU768111B2 (en) 2003-12-04
BR0010187A (pt) 2003-07-01
MXPA01011057A (es) 2003-06-24
DE60033141T2 (de) 2007-11-15
DE60033141D1 (de) 2007-03-15

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