ATE352622T1 - Verfahren zum entfernen von den n-terminalen alaninresten mit aeromonas aminopeptidase - Google Patents

Verfahren zum entfernen von den n-terminalen alaninresten mit aeromonas aminopeptidase

Info

Publication number
ATE352622T1
ATE352622T1 AT00928135T AT00928135T ATE352622T1 AT E352622 T1 ATE352622 T1 AT E352622T1 AT 00928135 T AT00928135 T AT 00928135T AT 00928135 T AT00928135 T AT 00928135T AT E352622 T1 ATE352622 T1 AT E352622T1
Authority
AT
Austria
Prior art keywords
removal
alanine residue
terminal alanine
aeromonas aminopeptidase
aeromonas
Prior art date
Application number
AT00928135T
Other languages
English (en)
Inventor
Jacob S Tou
Douglas W Taylor
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Application granted granted Critical
Publication of ATE352622T1 publication Critical patent/ATE352622T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/06Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT00928135T 1999-04-30 2000-04-26 Verfahren zum entfernen von den n-terminalen alaninresten mit aeromonas aminopeptidase ATE352622T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13206299P 1999-04-30 1999-04-30

Publications (1)

Publication Number Publication Date
ATE352622T1 true ATE352622T1 (de) 2007-02-15

Family

ID=22452276

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00928135T ATE352622T1 (de) 1999-04-30 2000-04-26 Verfahren zum entfernen von den n-terminalen alaninresten mit aeromonas aminopeptidase

Country Status (14)

Country Link
EP (1) EP1173572B1 (de)
JP (1) JP2002542835A (de)
KR (1) KR20020011399A (de)
CN (1) CN1353755A (de)
AR (1) AR025156A1 (de)
AT (1) ATE352622T1 (de)
AU (1) AU768111B2 (de)
BR (1) BR0010187A (de)
CA (1) CA2370113A1 (de)
DE (1) DE60033141T2 (de)
ES (1) ES2280211T3 (de)
MX (1) MXPA01011057A (de)
WO (1) WO2000066761A2 (de)
ZA (1) ZA200108915B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743600B1 (en) * 1999-04-30 2004-06-01 Monsanto Technologies Llc Method of removing N-terminal alanine residues from polypeptides with Aeromonas aminopeptidase
DK1432793T3 (da) 2001-09-13 2009-12-07 Genentech Inc Aminopeptidase b2324
CN105319207A (zh) * 2014-08-01 2016-02-10 上海梅山钢铁股份有限公司 检测电镀锡前湿平整钢板清洗效果的测试液及检测方法
KR101795918B1 (ko) 2015-07-24 2017-11-10 주식회사 포스코 내시효성 및 소부경화성이 우수한 용융아연도금강판, 합금화 용융아연도금강판 및 그 제조방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763215A (en) * 1984-08-16 1998-06-09 Bio-Technology General Corporation Method of removing N-terminal amino acid residues from eucaryotic polypeptide analogs and polypeptides produced thereby

Also Published As

Publication number Publication date
AU4641500A (en) 2000-11-17
WO2000066761A3 (en) 2001-03-15
AU768111B2 (en) 2003-12-04
ES2280211T3 (es) 2007-09-16
DE60033141T2 (de) 2007-11-15
JP2002542835A (ja) 2002-12-17
EP1173572B1 (de) 2007-01-24
ZA200108915B (en) 2006-04-26
CA2370113A1 (en) 2000-11-09
DE60033141D1 (de) 2007-03-15
MXPA01011057A (es) 2003-06-24
CN1353755A (zh) 2002-06-12
BR0010187A (pt) 2003-07-01
KR20020011399A (ko) 2002-02-08
AR025156A1 (es) 2002-11-13
WO2000066761A2 (en) 2000-11-09
EP1173572A2 (de) 2002-01-23

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Legal Events

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