ZA200106945B - Kit for radiolabeling proteins with Yttrium-90. - Google Patents

Kit for radiolabeling proteins with Yttrium-90. Download PDF

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Publication number
ZA200106945B
ZA200106945B ZA200106945A ZA200106945A ZA200106945B ZA 200106945 B ZA200106945 B ZA 200106945B ZA 200106945 A ZA200106945 A ZA 200106945A ZA 200106945 A ZA200106945 A ZA 200106945A ZA 200106945 B ZA200106945 B ZA 200106945B
Authority
ZA
South Africa
Prior art keywords
kit
dtpa
chelator
buffer
antibody
Prior art date
Application number
ZA200106945A
Other languages
English (en)
Inventor
Paul Chinn
Original Assignee
Idec Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idec Pharma Corp filed Critical Idec Pharma Corp
Publication of ZA200106945B publication Critical patent/ZA200106945B/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/534Production of labelled immunochemicals with radioactive label
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200106945A 1999-03-01 2001-08-22 Kit for radiolabeling proteins with Yttrium-90. ZA200106945B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25933899A 1999-03-01 1999-03-01

Publications (1)

Publication Number Publication Date
ZA200106945B true ZA200106945B (en) 2002-11-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200106945A ZA200106945B (en) 1999-03-01 2001-08-22 Kit for radiolabeling proteins with Yttrium-90.

Country Status (36)

Country Link
US (3) US6994840B1 (ru)
EP (2) EP1156835B1 (ru)
JP (1) JP4558947B2 (ru)
KR (1) KR100734023B1 (ru)
CN (1) CN1251767C (ru)
AT (1) ATE428446T1 (ru)
AU (1) AU780311B2 (ru)
BG (1) BG65568B1 (ru)
BR (1) BR0008635A (ru)
CA (1) CA2362908C (ru)
CY (1) CY1109211T1 (ru)
CZ (1) CZ20013127A3 (ru)
DE (2) DE1156835T1 (ru)
DK (1) DK1156835T3 (ru)
EE (1) EE05582B1 (ru)
ES (1) ES2165830T3 (ru)
GR (1) GR20010300078T1 (ru)
HK (1) HK1045656B (ru)
HR (1) HRP20010713A2 (ru)
HU (1) HU227986B1 (ru)
IL (2) IL145112A0 (ru)
ME (1) ME00783B (ru)
MX (1) MXPA01008745A (ru)
MY (1) MY133346A (ru)
NO (1) NO330728B1 (ru)
NZ (1) NZ513667A (ru)
PL (1) PL204239B1 (ru)
PT (1) PT1156835E (ru)
RS (1) RS50342B (ru)
RU (1) RU2221807C2 (ru)
SI (1) SI1156835T1 (ru)
SK (1) SK287650B6 (ru)
TW (1) TWI283178B (ru)
UA (1) UA75036C2 (ru)
WO (1) WO2000052031A2 (ru)
ZA (1) ZA200106945B (ru)

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EP2236172A1 (en) 2003-11-04 2010-10-06 Novartis Vaccines and Diagnostics, Inc. Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers
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Also Published As

Publication number Publication date
HUP0105489A2 (hu) 2002-05-29
HU227986B1 (en) 2012-07-30
ES2165830T3 (es) 2009-06-19
DE1156835T1 (de) 2002-05-23
BG105853A (en) 2002-06-28
PT1156835E (pt) 2009-07-24
EE05582B1 (et) 2012-10-15
US7618613B2 (en) 2009-11-17
KR20020002474A (ko) 2002-01-09
CN1251767C (zh) 2006-04-19
CN1345249A (zh) 2002-04-17
KR100734023B1 (ko) 2007-06-29
MY133346A (en) 2007-11-30
EP1156835A2 (en) 2001-11-28
US20070297978A1 (en) 2007-12-27
CA2362908C (en) 2012-01-31
TWI283178B (en) 2007-07-01
ATE428446T1 (de) 2009-05-15
RS50342B (sr) 2009-11-10
CZ20013127A3 (cs) 2002-02-13
BG65568B1 (bg) 2008-12-30
UA75036C2 (ru) 2006-03-15
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AU780311B2 (en) 2005-03-17
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