ZA200103478B - Use of an enterobacterium protein OmpA for specific targeting towards antigen-presenting cells. - Google Patents

Use of an enterobacterium protein OmpA for specific targeting towards antigen-presenting cells. Download PDF

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Publication number
ZA200103478B
ZA200103478B ZA200103478A ZA200103478A ZA200103478B ZA 200103478 B ZA200103478 B ZA 200103478B ZA 200103478 A ZA200103478 A ZA 200103478A ZA 200103478 A ZA200103478 A ZA 200103478A ZA 200103478 B ZA200103478 B ZA 200103478B
Authority
ZA
South Africa
Prior art keywords
protein
antigen
fragment
active substance
biologically active
Prior art date
Application number
ZA200103478A
Other languages
English (en)
Inventor
Jean-Yves Bonnefoy
Sybille Lecoanet
Jean-Pierre Aubry
Pascale Jeannin
Thierry Baussant
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of ZA200103478B publication Critical patent/ZA200103478B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA200103478A 1998-11-06 2001-04-30 Use of an enterobacterium protein OmpA for specific targeting towards antigen-presenting cells. ZA200103478B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9814007A FR2785542B1 (fr) 1998-11-06 1998-11-06 UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES

Publications (1)

Publication Number Publication Date
ZA200103478B true ZA200103478B (en) 2002-02-12

Family

ID=9532467

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200103478A ZA200103478B (en) 1998-11-06 2001-04-30 Use of an enterobacterium protein OmpA for specific targeting towards antigen-presenting cells.

Country Status (14)

Country Link
EP (1) EP1124577B1 (de)
JP (1) JP2002529428A (de)
CN (1) CN1181890C (de)
AT (1) ATE247978T1 (de)
AU (1) AU764205B2 (de)
BR (1) BR9915071A (de)
CA (1) CA2350183A1 (de)
DE (1) DE69910809T2 (de)
DK (1) DK1124577T3 (de)
ES (1) ES2205946T3 (de)
FR (1) FR2785542B1 (de)
PT (1) PT1124577E (de)
WO (1) WO2000027432A1 (de)
ZA (1) ZA200103478B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790960B1 (fr) * 1999-03-15 2002-10-31 Pf Medicament Utilisation de fractions membranaires bacteriennes a activite immunostimulante dans le traitement de cancers, leurs procedes de preparation et les compositions pharmaceutiques les contenant
FR2790959B1 (fr) * 1999-03-15 2003-06-27 Pf Medicament Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant
JP2003507433A (ja) * 1999-08-20 2003-02-25 ザ ゼネラル ホスピタル コーポレーション 敗血症治療において治療に用いる対象としての外膜タンパク質a、ペプチドグリカン関連リポタンパク質およびムレインリポタンパク質
FR2803302B1 (fr) * 2000-01-04 2004-12-10 Pf Medicament Procede de preparation d'un polypeptide soluble en solvant aqueux en absence de detergent
FR2809014A1 (fr) * 2000-05-16 2001-11-23 Pf Medicament Utilisation d'une proteine ompa d'enterobacterie comme agent antimicrobien
FR2822071B1 (fr) * 2001-03-15 2005-07-01 Pf Medicament Utilisation d'une fraction membranaire de bacteries a gram negatif pour induire la maturation des cellules dendritiques
EP2377883A1 (de) * 2010-04-15 2011-10-19 Universite d'Auvergne Clermont I Antagonisten zur Vorbeugung oder Behandlung von entzündlicher Darmerkrankung, speziell von Morbus Crohn
CN102286106B (zh) * 2011-07-11 2013-05-01 中国人民解放军军事医学科学院微生物流行病研究所 夹心外膜蛋白展示载体及应用其制备的大肠埃希菌疫苗
KR20170011221A (ko) * 2015-07-22 2017-02-02 이화여자대학교 산학협력단 클렙시엘라균 감염질환의 예방용 백신

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726472B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
US5853719A (en) * 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
FR2748476B1 (fr) * 1996-05-07 1998-08-14 Pf Medicament Complexe immunogene, son utilisation, son procede de preparation et vaccin le contenant

Also Published As

Publication number Publication date
CA2350183A1 (fr) 2000-05-18
FR2785542A1 (fr) 2000-05-12
ES2205946T3 (es) 2004-05-01
AU764205B2 (en) 2003-08-14
DE69910809T2 (de) 2004-06-17
CN1181890C (zh) 2004-12-29
EP1124577A1 (de) 2001-08-22
EP1124577B1 (de) 2003-08-27
DE69910809D1 (de) 2003-10-02
AU1164100A (en) 2000-05-29
WO2000027432A1 (fr) 2000-05-18
FR2785542B1 (fr) 2001-02-09
BR9915071A (pt) 2001-07-17
ATE247978T1 (de) 2003-09-15
CN1326360A (zh) 2001-12-12
PT1124577E (pt) 2004-01-30
DK1124577T3 (da) 2003-12-08
JP2002529428A (ja) 2002-09-10

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