ZA200006475B - Factors affecting tumor necrosis factor receptor releasing enzyme activity. - Google Patents
Factors affecting tumor necrosis factor receptor releasing enzyme activity. Download PDFInfo
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- ZA200006475B ZA200006475B ZA200006475A ZA200006475A ZA200006475B ZA 200006475 B ZA200006475 B ZA 200006475B ZA 200006475 A ZA200006475 A ZA 200006475A ZA 200006475 A ZA200006475 A ZA 200006475A ZA 200006475 B ZA200006475 B ZA 200006475B
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A—HUMAN NECESSITIES
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/525—Tumor necrosis factor [TNF]
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Immunology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
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- Toxicology (AREA)
- Hematology (AREA)
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- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Orthopedic Medicine & Surgery (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US09/081,385 US6593456B1 (en) | 1996-11-06 | 1998-05-14 | Tumor necrosis factor receptor releasing enzyme |
Publications (1)
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| ZA200006475B true ZA200006475B (en) | 2001-05-25 |
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| ZA200006475A ZA200006475B (en) | 1998-05-14 | 2000-11-09 | Factors affecting tumor necrosis factor receptor releasing enzyme activity. |
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| US (6) | US6593456B1 (ko) |
| EP (1) | EP1076710B1 (ko) |
| JP (1) | JP2002514402A (ko) |
| KR (1) | KR100891899B1 (ko) |
| CN (1) | CN100368547C (ko) |
| AR (1) | AR020588A1 (ko) |
| AT (1) | ATE376063T1 (ko) |
| AU (1) | AU768093B2 (ko) |
| BR (1) | BR9910458A (ko) |
| CA (1) | CA2328133C (ko) |
| DE (1) | DE69937344T2 (ko) |
| ES (1) | ES2294841T3 (ko) |
| IL (1) | IL139566A0 (ko) |
| MY (1) | MY135968A (ko) |
| NZ (1) | NZ507977A (ko) |
| RU (1) | RU2279478C2 (ko) |
| TW (1) | TWI244501B (ko) |
| WO (1) | WO1999058559A2 (ko) |
| ZA (1) | ZA200006475B (ko) |
Families Citing this family (23)
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| US6593456B1 (en) | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| US6930084B1 (en) | 1996-11-06 | 2005-08-16 | The Regents Of The University Of California | Treating arthritis with TNF receptor releasing enzyme |
| NZ335864A (en) | 1996-11-06 | 2001-09-28 | Univ California | Isolated tumor necrosis factor receptor releasing enzyme (TRRE), compositions comprising the enzyme and methods of the use in modulation of TNF levels |
| US20050191661A1 (en) * | 1996-11-06 | 2005-09-01 | Tetsuya Gatanaga | Treatment of inflammatory disease by cleaving TNF receptors |
| WO2001064856A2 (en) * | 2000-02-28 | 2001-09-07 | The Government Of The United States Of America, A S Represented By The Secretary, Department Of Hea Lth And Human Services | Regulators of type-1 tumor necrosis factor receptor and other cytokine receptor shedding |
| WO2003027279A1 (fr) * | 2001-09-25 | 2003-04-03 | Sony Corporation | Inhibiteur de l'histone acetylase de p300 |
| WO2004031388A1 (ja) * | 2002-07-25 | 2004-04-15 | Sony Corporation | 転写調節に関与する因子 |
| US20090204076A1 (en) * | 2003-02-03 | 2009-08-13 | Barry Peter Liversidge | Medical Injector |
| CN100375750C (zh) * | 2003-05-15 | 2008-03-19 | 中国疾病预防控制中心病毒病预防控制所 | 抑制人肿瘤坏死因子活性的寡聚核苷酸 |
| US7738952B2 (en) * | 2003-06-09 | 2010-06-15 | Palo Alto Investors | Treatment of conditions through modulation of the autonomic nervous system |
| WO2005030241A2 (en) * | 2003-09-23 | 2005-04-07 | Meyer Pharmaceuticals, Llc | Treating inflammation using a biological agent that causes cells to release cytokine receptors |
| WO2005087947A2 (en) * | 2004-03-09 | 2005-09-22 | Meyer Pharmaceuticals Llc | Bioengineered proteolytic enzymes with enhanced specificity for cytokine receptors |
| GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| ITRM20050064A1 (it) * | 2005-02-16 | 2006-08-17 | Univ Siena | Peptide poliepitopico derivato dalla timidilato sintetasi avente attivita' immunologica e antitumorale e composizioni farmaceutiche relative. |
| WO2007022474A2 (en) * | 2005-08-19 | 2007-02-22 | Cylene Pharmaceuticals, Inc. | HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF |
| US20090325944A1 (en) * | 2006-04-12 | 2009-12-31 | Suzanne Walker Kahne | Methods and Compositions for Modulating Glycosylation |
| CN101484199B (zh) | 2006-06-30 | 2014-06-25 | 艾伯维生物技术有限公司 | 自动注射装置 |
| WO2008156676A1 (en) | 2007-06-15 | 2008-12-24 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating o-glycosylation |
| CN102458517B (zh) | 2009-04-29 | 2014-07-23 | 阿布维生物技术有限公司 | 自动注射装置 |
| JP2012528858A (ja) | 2009-06-01 | 2012-11-15 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | Ｏ−ＧｌｃＮＡｃ転移酵素阻害剤およびその使用 |
| GB0915877D0 (en) * | 2009-09-10 | 2009-10-14 | E Therapeutics Plc | Cancer cell apoptosis |
| EP2512558A4 (en) | 2009-12-15 | 2014-08-13 | Abbvie Biotechnology Ltd | IMPROVED TRIP KNOB FOR AUTOMATIC INJECTION DEVICE |
| EP2749305B1 (en) | 2011-01-24 | 2017-11-01 | AbbVie Biotechnology Ltd | Automatic injection devices having overmolded gripping surfaces |
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| US4340586A (en) * | 1977-02-18 | 1982-07-20 | Adam Bekierkunst | Pharmaceutical preparation for treating disorders of the skin |
| US5192537A (en) * | 1984-03-30 | 1993-03-09 | Cellcor Inc. | Method of treating renal cell carcinoma using activated mononuclear cells, renal tumor antigen and cimetidine |
| US5643740A (en) * | 1983-02-24 | 1997-07-01 | Ronald J. Billing | Monoclonal antibody specific for activated lymphocytes and monocytes |
| US5001061A (en) * | 1983-06-22 | 1991-03-19 | Lubrizol Genetics, Inc. | nifD promoter of Bradyrhizobium |
| DE3343530A1 (de) * | 1983-12-01 | 1985-06-13 | Max Planck Gesellschaft | Arzneimittel mit verbesserter penetration der gewebsmembran |
| JPH0611709B2 (ja) * | 1984-10-19 | 1994-02-16 | チロン コーポレイション | 角膜基質創傷の治療のための組成物 |
| US4761371A (en) | 1985-02-12 | 1988-08-02 | Genentech, Inc. | Insulin receptor |
| US4695590A (en) * | 1986-05-05 | 1987-09-22 | California Health Technologies | Method for retarding aging |
| US5017566A (en) * | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US5140043A (en) * | 1989-04-17 | 1992-08-18 | Duke University | Stable ascorbic acid compositions |
| US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| US6232446B1 (en) * | 1989-05-18 | 2001-05-15 | Yeda Research And Development Co. Ltd. | TNF ligands |
| US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
| US5270326A (en) * | 1990-11-21 | 1993-12-14 | University Of Florida | Treatment for tissue ulceration |
| US5268384A (en) * | 1990-11-21 | 1993-12-07 | Galardy Richard E | Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors |
| EP0534907B1 (en) * | 1991-09-26 | 1998-08-05 | Nippon Zoki Pharmaceutical Co., Ltd. | The use of furanone derivatives for the prevention or treatment of autoimmune diseases |
| GB9214857D0 (en) * | 1992-07-13 | 1992-08-26 | Medical Res Council | Human nucleic acid fragments and their use |
| IL107268A0 (en) * | 1993-10-12 | 1994-01-25 | Yeda Res & Dev | Molecules influencing the shedding of the tnf receptor, their preparation and their use |
| CA2153480A1 (en) * | 1993-11-12 | 1995-06-01 | Kenichi Matsubara | Gene signature |
| EP0693556B1 (en) * | 1994-01-28 | 2004-10-06 | Ajinomoto Co., Inc. | Transglutaminase originating in japanese oyster |
| IL111125A0 (en) | 1994-05-11 | 1994-12-29 | Yeda Res & Dev | Soluble oligomeric tnf/ngf super family ligand receptors and their use |
| US5741667A (en) | 1994-05-27 | 1998-04-21 | Genentech, Inc. | Tumor necrosis factor receptor-associated factors |
| ZA955430B (en) | 1994-07-07 | 1997-02-13 | Res Dev Foundation | Tumor necrosis factor receptor-ii associated protein kinase and method for their use |
| FR2725213B1 (fr) | 1994-10-04 | 1996-11-08 | Rhone Poulenc Rorer Sa | Vecteurs viraux et utilisation en therapie genique |
| PL188795B1 (pl) | 1995-06-07 | 2005-04-29 | Glaxo Group Ltd | Związek wiążący się z receptorem trombopoetyny, kompozycja farmaceutyczna i zastosowanie związku wiążącego się z receptorem trombopoetyny |
| US5968506A (en) * | 1995-08-04 | 1999-10-19 | Geron Corporation | Purified telomerase |
| US6090605A (en) * | 1996-03-11 | 2000-07-18 | The Board Of Trustees Of The University Of Arkansas | Purified porcine kidney L-fucose kinase |
| US6068838A (en) * | 1996-04-29 | 2000-05-30 | Baxter Aktiengesellschaft | Purified multimerase |
| US5834236A (en) * | 1996-06-27 | 1998-11-10 | The Salk Institute For Biological Studies | AATT repeat transcription enhancer element |
| US5853977A (en) * | 1996-07-12 | 1998-12-29 | Schering Corporation | Mammalian TNF-α convertases |
| US6022948A (en) * | 1996-09-17 | 2000-02-08 | Washington University | Method of cell surface activation and inhibition |
| NZ335864A (en) | 1996-11-06 | 2001-09-28 | Univ California | Isolated tumor necrosis factor receptor releasing enzyme (TRRE), compositions comprising the enzyme and methods of the use in modulation of TNF levels |
| US6593456B1 (en) | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| CN1268980A (zh) * | 1997-03-05 | 2000-10-04 | 华盛顿州大学 | 用于鉴定选择性抑制丙型肝炎病毒复制的试剂的新筛选方法 |
| US6911314B2 (en) | 1999-05-14 | 2005-06-28 | The Regents Of The University Of California | Screening for drugs that affect TNF receptor releasing enzyme |
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| US7399465B2 (en) | 2008-07-15 |
| AR020588A1 (es) | 2002-05-22 |
| NZ507977A (en) | 2004-04-30 |
| WO1999058559A2 (en) | 1999-11-18 |
| US20050090647A1 (en) | 2005-04-28 |
| US6593456B1 (en) | 2003-07-15 |
| MY135968A (en) | 2008-07-31 |
| US20080160002A1 (en) | 2008-07-03 |
| CN100368547C (zh) | 2008-02-13 |
| US20080102075A1 (en) | 2008-05-01 |
| BR9910458A (pt) | 2001-01-02 |
| IL139566A0 (en) | 2002-02-10 |
| DE69937344T2 (de) | 2008-07-17 |
| ES2294841T3 (es) | 2008-04-01 |
| CN1309709A (zh) | 2001-08-22 |
| CA2328133C (en) | 2009-08-11 |
| ATE376063T1 (de) | 2007-11-15 |
| US6955894B1 (en) | 2005-10-18 |
| CA2328133A1 (en) | 1999-11-18 |
| WO1999058559A3 (en) | 2000-01-20 |
| TWI244501B (en) | 2005-12-01 |
| EP1076710B1 (en) | 2007-10-17 |
| KR20010043586A (ko) | 2001-05-25 |
| US20050158826A1 (en) | 2005-07-21 |
| RU2279478C2 (ru) | 2006-07-10 |
| AU768093B2 (en) | 2003-12-04 |
| AU3996099A (en) | 1999-11-29 |
| KR100891899B1 (ko) | 2009-04-07 |
| US8101174B2 (en) | 2012-01-24 |
| JP2002514402A (ja) | 2002-05-21 |
| WO1999058559B1 (en) | 2000-03-16 |
| DE69937344D1 (de) | 2007-11-29 |
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