ZA200005445B - Improved immunodiagnostic assays using reducing agents. - Google Patents
Improved immunodiagnostic assays using reducing agents. Download PDFInfo
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- ZA200005445B ZA200005445B ZA200005445A ZA200005445A ZA200005445B ZA 200005445 B ZA200005445 B ZA 200005445B ZA 200005445 A ZA200005445 A ZA 200005445A ZA 200005445 A ZA200005445 A ZA 200005445A ZA 200005445 B ZA200005445 B ZA 200005445B
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- Prior art keywords
- hcv
- reducing agent
- solid phase
- protein
- polypeptide
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
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| EP (2) | EP1071955B2 (cs) |
| JP (2) | JP2002512370A (cs) |
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| CN (1) | CN1305589A (cs) |
| AT (2) | ATE401340T1 (cs) |
| AU (1) | AU751362B2 (cs) |
| BR (1) | BRPI9909678B8 (cs) |
| CA (2) | CA2324970C (cs) |
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| DE (2) | DE69920895T3 (cs) |
| DK (2) | DK1471074T3 (cs) |
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| HU (1) | HUP0101719A3 (cs) |
| IL (1) | IL138791A0 (cs) |
| PL (1) | PL343469A1 (cs) |
| PT (2) | PT1471074E (cs) |
| TR (4) | TR200101647T2 (cs) |
| WO (1) | WO1999054735A1 (cs) |
| ZA (1) | ZA200005445B (cs) |
Families Citing this family (24)
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| PT1090033E (pt) * | 1998-06-24 | 2005-05-31 | Innogenetics Nv | Particulas de proteinas de envelope do hcv: utilizacao para vacinacao |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| EP1947185B1 (en) * | 2000-08-17 | 2011-07-20 | Tripep Ab | HCV NS3/4A encoding nucleic acid |
| AR035868A1 (es) | 2001-04-24 | 2004-07-21 | Innogenetics Nv | Un acido nucleico recombinante que codifica una proteina de un peptido lider de lisozima de ave o equivalente funcional, un vector que lo comprende, una celula huesped, un metodo para producir una proteina de envoltura del hcv o una parte de la misma. |
| JP2004108914A (ja) * | 2002-09-18 | 2004-04-08 | Kudo Norio | コラーゲンの測定方法 |
| WO2004041853A2 (en) * | 2002-11-08 | 2004-05-21 | Innogenetics N.V. | Hcv vaccine compositions comprising e1 and ns3 peptides |
| US20050014136A1 (en) * | 2003-05-28 | 2005-01-20 | Innogenetics N.V. | Modified HCV NS5 |
| CN1871518B (zh) | 2003-10-28 | 2010-08-25 | 株式会社先端生命科学研究所 | 丙型肝炎病毒的检测方法 |
| WO2008006017A1 (en) * | 2006-07-07 | 2008-01-10 | Pall Corporation | Use of denaturing agents during affinity capture |
| US20100304353A1 (en) * | 2007-07-16 | 2010-12-02 | Pfizer Inc | Methods of improving a genomic marker index of dairy animals and products |
| US20110123983A1 (en) * | 2007-09-12 | 2011-05-26 | Pfizer Inc. | Methods of Using Genetic Markers and Related Epistatic Interactions |
| CN101883869A (zh) * | 2007-10-03 | 2010-11-10 | 美国辉瑞有限公司 | 有角牛和无角牛的遗传标志及其相关方法 |
| JP2011505872A (ja) * | 2007-12-17 | 2011-03-03 | ファイザー・インク | 乳用動物および乳用生産物の遺伝的プロフィールを改良する方法 |
| EP2318838B1 (en) | 2008-07-16 | 2013-09-04 | Radiometer Medical ApS | High capacity solid phase |
| CN102081018A (zh) * | 2009-11-30 | 2011-06-01 | 希森美康株式会社 | 样品的预处理方法及hcv的免疫测定方法 |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| WO2016069762A2 (en) * | 2014-10-29 | 2016-05-06 | Abbott Laboratories | Subject anti-hcv antibody detection assays employing ns3 capture peptides |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN109678954B (zh) * | 2018-12-29 | 2022-01-07 | 山东莱博生物科技有限公司 | 一对能够特异性识别hcv ns3蛋白的单克隆抗体及其应用 |
| CN110988362B (zh) * | 2019-12-20 | 2023-11-14 | 迈克生物股份有限公司 | 抗组蛋白抗体测定试剂、试剂盒及其使用方法 |
| CN112225783B (zh) * | 2020-09-16 | 2021-08-31 | 东莞市朋志生物科技有限公司 | Hcv重组抗原及其突变体 |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| CN113219169B (zh) * | 2021-05-22 | 2021-12-17 | 北京金诺百泰生物技术有限公司 | 生物检测用封闭剂及其制备方法、包被板及应用该包被板的试剂盒 |
| CN115112897B (zh) * | 2021-12-10 | 2024-11-01 | 中山大学附属第八医院（深圳福田） | 一种用于鉴别抗体检测生物学假阳性的方法 |
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| EP0139526A2 (en) * | 1983-10-20 | 1985-05-02 | Warner-Lambert Company | An insolubilized stable specific binding protein |
| US4616078A (en) * | 1985-04-08 | 1986-10-07 | Eli Lilly And Company | Process for purifying proinsulin-like materials |
| CA1340877C (en) * | 1987-12-28 | 2000-01-18 | Takashi Sugiyama | Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology |
| ATE92633T1 (de) * | 1988-05-11 | 1993-08-15 | Abbott Lab | Verfahren zur erhoehung der spezifizitaet in kompetitiven immuntests. |
| US4923967A (en) * | 1988-09-26 | 1990-05-08 | Eli Lilly And Company | Purification and refolding of recombinant proteins |
| DE69133617D1 (de) * | 1990-04-04 | 2009-07-23 | Novartis Vaccines & Diagnostic | Protease von Hepatitis C Virus |
| US6194140B1 (en) * | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
| US5606031A (en) * | 1990-04-06 | 1997-02-25 | Lile; Jack | Production and purification of biologically active recombinant neurotrophic protein in bacteria |
| JP3516681B2 (ja) * | 1991-06-24 | 2004-04-05 | カイロン コーポレイション | Ｃ型肝炎ウイルス（ｈｃｖ）ポリペプチド |
| JP3225468B2 (ja) | 1992-08-28 | 2001-11-05 | ダイナボット株式会社 | 抗体測定用試薬 |
| FI946066L (fi) | 1993-04-27 | 1994-12-23 | Innogenetics Nv | Hepatiitti-C viruksen genotyyppien uudet sekvenssit ja niiden käyttö terapeuttisina ja diagnostisina aineina |
| ATE274578T1 (de) | 1993-11-04 | 2004-09-15 | Innogenetics Nv | Von menschlichen t-zellen immunodominante epitopen des virus der c-hepatitis |
| ATE208481T1 (de) | 1994-06-23 | 2001-11-15 | Energy Answers Corp | Anlage zur erzeugung von asche enthaltenden produkten und energie aus abfällen |
| PT721505E (pt) * | 1994-07-29 | 2002-10-31 | Innogenetics Nv | Proteinas do envelope do virus da hepatite c purificadas para utilizacao em diagnostico e terapeutica |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| JPH0862219A (ja) | 1994-08-19 | 1996-03-08 | Dainabotsuto Kk | 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法 |
| CA2201703A1 (en) | 1994-10-21 | 1996-05-09 | Geert Maertens | New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents |
| US5705330A (en) | 1995-04-14 | 1998-01-06 | Abbott Laboratories | Chemiluminescent immunoassay for antibody detection |
| US5616460A (en) * | 1995-06-07 | 1997-04-01 | Abbott Laboratories | Buffer composition for reagents for immunoassay |
| IL126460A (en) | 1996-05-24 | 2007-07-04 | Novartis Vaccines & Diagnostic | Multiple epitope fusion protein |
| DE69827789T2 (de) * | 1997-01-13 | 2005-11-10 | Rodel, Inc., Newark | Verfahren zum herstellen von einem photolithographisch gemusterten kunststoffpolierkissen |
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- 1999-04-15 EP EP99920678A patent/EP1071955B2/en not_active Expired - Lifetime
- 1999-04-15 DE DE69920895T patent/DE69920895T3/de not_active Expired - Lifetime
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- 1999-04-15 JP JP2000545027A patent/JP2002512370A/ja active Pending
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- 1999-04-15 HU HU0101719A patent/HUP0101719A3/hu unknown
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- 1999-04-15 ES ES99920678T patent/ES2230851T5/es not_active Expired - Lifetime
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- 1999-04-15 KR KR1020007011555A patent/KR20010042807A/ko not_active Ceased
- 1999-04-15 AT AT04103238T patent/ATE401340T1/de active
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- 1999-04-15 TR TR2002/02213T patent/TR200202213T2/xx unknown
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- 1999-04-15 DE DE69939132T patent/DE69939132D1/de not_active Expired - Lifetime
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2000
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2005
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2006
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2008
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