YU89875A - Process for obtaining imidazole derivatives - Google Patents

Process for obtaining imidazole derivatives

Info

Publication number
YU89875A
YU89875A YU00898/75A YU89875A YU89875A YU 89875 A YU89875 A YU 89875A YU 00898/75 A YU00898/75 A YU 00898/75A YU 89875 A YU89875 A YU 89875A YU 89875 A YU89875 A YU 89875A
Authority
YU
Yugoslavia
Prior art keywords
unsubstituted
alkyl
substituted
infections
imidazole derivatives
Prior art date
Application number
YU00898/75A
Other languages
English (en)
Inventor
Dr P Strehlke
Dr H J Kessler
U Redmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742418502 external-priority patent/DE2418502C3/de
Priority claimed from DE19752510130 external-priority patent/DE2510130A1/de
Priority claimed from DE19752510781 external-priority patent/DE2510781A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of YU89875A publication Critical patent/YU89875A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
YU00898/75A 1974-04-11 1975-04-09 Process for obtaining imidazole derivatives YU89875A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19742418502 DE2418502C3 (de) 1974-04-11 1974-04-11 Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19752510130 DE2510130A1 (de) 1975-03-06 1975-03-06 Imidazolderivate und verfahren zu ihrer herstellung
DE19752510781 DE2510781A1 (de) 1975-03-07 1975-03-07 Imidazolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
YU89875A true YU89875A (en) 1982-05-31

Family

ID=27185894

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00898/75A YU89875A (en) 1974-04-11 1975-04-09 Process for obtaining imidazole derivatives

Country Status (17)

Country Link
US (1) US4006243A (fr)
JP (1) JPS6018654B2 (fr)
AT (1) AT341518B (fr)
CA (1) CA1051908A (fr)
CH (1) CH612185A5 (fr)
CS (1) CS194221B2 (fr)
DD (1) DD121515A5 (fr)
DK (1) DK139909C (fr)
ES (1) ES436546A1 (fr)
FR (1) FR2267101B1 (fr)
GB (1) GB1510016A (fr)
HU (1) HU172895B (fr)
IE (1) IE40911B1 (fr)
IL (1) IL47061A (fr)
NL (1) NL7504387A (fr)
SE (1) SE418498B (fr)
YU (1) YU89875A (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT328587B (de) * 1973-08-20 1976-03-25 Vianova Kunstharz Ag Verfahren zur herstellung von wasserigen uberzugsmitteln
US4237158A (en) * 1975-02-05 1980-12-02 Rohm And Haas Company 1-Substituted aralkyl imidazoles and their use as fungicides
DE2549798C3 (de) * 1975-11-06 1978-06-29 Nordmark-Werke Gmbh, 2000 Hamburg 1,2-Dipheny l-3-(imidazo Wl-1 )propene, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
US4115578A (en) * 1975-12-18 1978-09-19 Rohm And Haas Company 1-Substituted aralkyl imidazoles
US4118461A (en) * 1975-12-18 1978-10-03 Rohm And Haas Company 1-Substituted aralkyl imidazoles
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
US4284641A (en) * 1977-08-26 1981-08-18 Burroughs Wellcome Co. Pharmaceutically active imidazole derivatives
US4431815A (en) * 1977-08-26 1984-02-14 Burroughs Wellcome Co. 1-[3-(2,4-Dichlorophenyl)propyl]imidazole and salts thereof
US4396771A (en) * 1977-10-19 1983-08-02 Burroughs Wellcome Co. Imidazole derivatives and salts thereof
IT1097314B (it) * 1978-07-26 1985-08-31 Recordati Chem Pharm Derivati dell'imidazolo ad attivita' anticonvulsivante
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
DK531479A (da) * 1979-01-19 1980-07-20 Pfizer Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
DK157860C (da) * 1979-06-07 1990-07-30 Shionogi & Co Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf
US4218461A (en) * 1979-08-15 1980-08-19 E. R. Squibb & Sons, Inc. 2,3-Dihydro-2-[(1H-imidazol-1-yl)-methylene]-1H-inden-1-ones
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
CA1156661A (fr) * 1980-02-25 1983-11-08 Hoffmann-La Roche Limited Derives de phenoxy-aminopropanol
JPS57502126A (fr) * 1980-12-05 1982-12-02
IL66242A0 (en) * 1981-07-23 1982-11-30 Erba Farmitalia N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene,indan and 2-substituted-1-chroman,their preparation and pharmaceutical compositions containing them
JPS58150566A (ja) * 1982-03-03 1983-09-07 Yoshitomi Pharmaceut Ind Ltd 新規イミダゾ−ル誘導体
ES523609A0 (es) * 1982-07-05 1985-03-01 Erba Farmitalia Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.
GB2126218B (en) * 1982-08-14 1986-01-22 Wellcome Found Imidazoles
JPS60142965A (ja) * 1983-09-05 1985-07-29 Yoshitomi Pharmaceut Ind Ltd イミダゾ−ル誘導体の製造法
EP0149976A3 (fr) * 1983-12-30 1986-12-10 Ciba-Geigy Ag Imidazoles substitués
US4755526A (en) * 1984-06-18 1988-07-05 Eli Lilly And Company Method of inhibiting aromatase
US4937250A (en) * 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US5459145A (en) * 1988-01-19 1995-10-17 Pfizer Inc. Calcium independent camp phosphodiesterase inhibitor antidepressant
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására
CA1329614C (fr) * 1987-05-02 1994-05-17 Rainer Buerstinghaus Azoles substituees en n
US5280036A (en) * 1987-05-02 1994-01-18 Basf Aktiengesellschaft N-phenoxyphenyloxymethyl substituted azoles and method for controlling pests therewith
US5214064A (en) * 1987-05-02 1993-05-25 Basf Aktiengesellschaft Phenoxyphenylmethyl substituted azoles and pesticidal composition thereof
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives
US5395935A (en) * 1992-05-08 1995-03-07 Pfizer Inc. Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents
AU2352295A (en) * 1994-04-27 1995-11-16 Nippon Soda Co., Ltd. Imidazole derivative and process for producing the same
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
DE19541146A1 (de) * 1995-10-25 1997-04-30 Schering Ag Imidazolderivate und deren Verwendung als Stickstoffmonoxid-Synthase-Inhibitoren
US6297239B1 (en) 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
AU2477400A (en) 1998-12-08 2000-06-26 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
US6632818B2 (en) 2000-01-12 2003-10-14 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
EP1178038A1 (fr) * 2000-08-04 2002-02-06 Aventis Cropscience S.A. Dérivés de phenylamidine fongicides
EP1650206A4 (fr) 2003-08-01 2006-12-20 Nippon Soda Co Composes de phenylazole, leur procede de production et antioxydants
UA106748C2 (uk) 2009-04-20 2014-10-10 Ф. Хоффманн-Ля Рош Аг Похідні проліну як інгібітори катепсину

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1908991B2 (de) * 1969-02-22 1977-05-26 Bayer Ag, 5090 Leverkusen Alpha, alpha-disubstituierte n- benzylimidazole und deren salze
DE2007794A1 (de) * 1970-02-20 1971-09-02 Farbenfabriken Bayer Aktiengesell schaft, 5090 Leverkusen Fungizide Mittel
US3833603A (en) * 1970-04-09 1974-09-03 Bayer Ag 1-(alpha,alpha-disubstituted 4-phenoxy-benzyl)imidazoles
NL7108387A (fr) * 1970-06-22 1971-12-24 Koninklijke Pharma Fab Nv
US3927017A (en) * 1974-06-27 1975-12-16 Janssen Pharmaceutica Nv 1-({62 -Aryl-{62 -R-ethyl)imidazoles

Also Published As

Publication number Publication date
SE418498B (sv) 1981-06-09
NL7504387A (nl) 1975-10-14
AT341518B (de) 1978-02-10
ES436546A1 (es) 1977-01-16
CS194221B2 (en) 1979-11-30
DK153075A (fr) 1975-10-12
IE40911B1 (en) 1979-09-12
IL47061A (en) 1978-08-31
JPS6018654B2 (ja) 1985-05-11
HU172895B (hu) 1978-12-28
ATA268675A (de) 1977-06-15
DK139909C (da) 1979-10-08
IE40911L (en) 1975-10-11
DK139909B (da) 1979-05-14
CA1051908A (fr) 1979-04-03
JPS50148357A (fr) 1975-11-27
FR2267101B1 (fr) 1980-01-25
SE7504123L (sv) 1975-12-19
DD121515A5 (fr) 1976-08-05
GB1510016A (en) 1978-05-10
FR2267101A1 (fr) 1975-11-07
CH612185A5 (fr) 1979-07-13
IL47061A0 (en) 1975-06-25
US4006243A (en) 1977-02-01
AU8002575A (en) 1976-10-14

Similar Documents

Publication Publication Date Title
YU89875A (en) Process for obtaining imidazole derivatives
ES483700A1 (es) Un procedimiento para preparar 2-nitroimidazols.
UA41865C2 (uk) Сполуки цефему, що мають антимікробну активність, та фармацевтична композиція, що їх містить
KR880012532A (ko) 신규 비시클릭화합물, 그의 제조방법 및 이 화합물로 되는 제약조성물
KR890000482A (ko) (8β)-1-알킬-6-(치환된) 에르 골린의 시클로알킬아미드
IE38096B1 (en) Pharmaceutical preparations comprising derivatives of phenyl propionic acid
ES8703870A1 (es) Procedimiento para preparar compuestos de 5-alquil-1-fenil-2-piperazinoalquilpirazolin-3-ona.
GB1185096A (en) Improvements in or relating to Antibiotic Derivatives and the manufacture thereof
ES446126A1 (es) Procedimiento para preparar 2-(fenoxialquiltio) imidazoles.
KR830001900A (ko) 페닐모르판과 그의 중간물질및 제조방법
IE44184L (en) Imidazole derivatives
KR870004038A (ko) 제초제 화합물의 제조방법
ES421182A1 (es) Procedimiento para preparar 1-fenoxi-3-fenoxi-etilamino-2- propanoles.
ES406098A1 (es) Procedimiento para la obtencion de derivados de 2,6-dini- tro-3,4-xilidena.
KR850003889A (ko) 복소환식 화합물
ES8305377A1 (es) Un procedimiento para la preparacion de un derivado de nitrosourea.
ES422827A1 (es) Procedimiento para la produccion de benzoilfenilguanidinas.
ES400414A1 (es) Procedimiento para la preparacion de derivados de piperidi-na n-sustituidos y su utilizacion como estabilizadores.
ES8306161A1 (es) Un procedimiento para la preparacion de nuevos derivados de nitrosourea.
ES442009A1 (es) Metodo para la preparacion de una composicion para combatir hongos fitopatogenos.
KR870001181A (ko) 시클로펜탄 유도체의 제조방법
ES344346A1 (es) Procedimiento para la preparacion de derivados heterocicli-cos.
ES437041A1 (es) Un procedimiento para preparar derivados de 1-ftalazona.
KR840001151A (ko) N-치환된-테트라하이드로프탈리미드 유도체의 제조방법
KR880002844A (ko) 펜옥사지논, 이의 제조방법 및 용도