YU46989B - Postupak za dobijanje hinolonskih jedinjenja - Google Patents

Postupak za dobijanje hinolonskih jedinjenja

Info

Publication number
YU46989B
YU46989B YU209788A YU209788A YU46989B YU 46989 B YU46989 B YU 46989B YU 209788 A YU209788 A YU 209788A YU 209788 A YU209788 A YU 209788A YU 46989 B YU46989 B YU 46989B
Authority
YU
Yugoslavia
Prior art keywords
procedure
obtaining
quinolone compounds
compounds
quinolone
Prior art date
Application number
YU209788A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU209788A (en
Inventor
L. Mc Lean
D.L. Roberts
K. Barron
K.J. Nichol
Original Assignee
The Boots Co. Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Co. Plc. filed Critical The Boots Co. Plc.
Publication of YU209788A publication Critical patent/YU209788A/xx
Publication of YU46989B publication Critical patent/YU46989B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
YU209788A 1987-11-18 1988-11-11 Postupak za dobijanje hinolonskih jedinjenja YU46989B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878726950A GB8726950D0 (en) 1987-11-18 1987-11-18 Chemical process

Publications (2)

Publication Number Publication Date
YU209788A YU209788A (en) 1990-08-31
YU46989B true YU46989B (sh) 1994-09-09

Family

ID=10627131

Family Applications (1)

Application Number Title Priority Date Filing Date
YU209788A YU46989B (sh) 1987-11-18 1988-11-11 Postupak za dobijanje hinolonskih jedinjenja

Country Status (28)

Country Link
US (2) US5011931A (enExample)
EP (2) EP0317149B1 (enExample)
JP (1) JPH02502013A (enExample)
KR (1) KR890701563A (enExample)
AT (1) ATE69221T1 (enExample)
AU (1) AU628305B2 (enExample)
BG (1) BG50157A3 (enExample)
CS (1) CS274487B2 (enExample)
DD (1) DD290188A5 (enExample)
DE (1) DE3866086D1 (enExample)
ES (1) ES2038310T3 (enExample)
FI (1) FI91063C (enExample)
GB (1) GB8726950D0 (enExample)
GR (1) GR3003378T3 (enExample)
HU (1) HU204511B (enExample)
IE (1) IE883366L (enExample)
IL (1) IL88358A (enExample)
MX (1) MX168918B (enExample)
NZ (1) NZ227008A (enExample)
PH (1) PH27439A (enExample)
PL (1) PL157191B1 (enExample)
PT (1) PT89024B (enExample)
RO (1) RO104615B1 (enExample)
SU (1) SU1766255A3 (enExample)
TW (1) TW204344B (enExample)
WO (1) WO1989004827A1 (enExample)
YU (1) YU46989B (enExample)
ZA (1) ZA888241B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
US6110489A (en) * 1998-05-01 2000-08-29 Cutler; Neal R. Use of quinolines and quinolones to treat male erectile dysfunction
US6194433B1 (en) 1998-10-05 2001-02-27 Neal R. Cutler Sexual dysfunction in females
US6132753A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6132757A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6303135B1 (en) 1999-07-08 2001-10-16 Neal R. Cutler Use of quinolines and quinolones to treat male erectile dysfunction
US6307050B1 (en) * 2000-08-29 2001-10-23 R. T. Alamo Venture I Llc Method of synthesizing flosequinan from 4-fluoroanthranilic acid
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6562838B2 (en) 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6531603B1 (en) 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6573382B2 (en) 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6660864B2 (en) 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
US6649764B2 (en) * 2001-10-25 2003-11-18 R. T. Alamo Ventures I, Llc Stereospecific enrichment of heterocyclic enantiomers
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US6730790B2 (en) * 2002-03-01 2004-05-04 R.T. Alamo Ventures I. Llc Chlorinated heterocyclic compounds and methods of synthesis
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920699A (en) * 1974-04-26 1975-11-18 Warner Lambert Co Process for the cyclization of aryl(methylsulfinyl)-methyl ketones and compounds produced thereby
US4192873A (en) * 1976-11-25 1980-03-11 Ciba-Geigy Corporation Anti-inflammatory 2-sulphonyl- (or -sulphinyl)-2'-aminoacetophenones
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
FR2532939A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, les compositions les renfermant et les nouveaux intermediaires obtenus
US4552884A (en) * 1984-01-13 1985-11-12 The Boots Company Plc Method of treating heart disease
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process

Also Published As

Publication number Publication date
FI91063B (fi) 1994-01-31
YU209788A (en) 1990-08-31
CS274487B2 (en) 1991-04-11
PL275880A1 (en) 1989-06-12
JPH02502013A (ja) 1990-07-05
KR890701563A (ko) 1989-12-21
RO104615B1 (en) 1992-11-03
AU2616388A (en) 1989-06-14
ATE69221T1 (de) 1991-11-15
MX168918B (es) 1993-06-14
SU1766255A3 (ru) 1992-09-30
HU204511B (en) 1992-01-28
GR3003378T3 (en) 1993-02-17
WO1989004827A1 (en) 1989-06-01
PL157191B1 (pl) 1992-05-29
EP0317149B1 (en) 1991-11-06
EP0343206A1 (en) 1989-11-29
PT89024A (pt) 1988-12-01
GB8726950D0 (en) 1987-12-23
CS748988A2 (en) 1990-09-12
FI893405A0 (fi) 1989-07-13
FI893405L (fi) 1989-07-13
HUT53085A (en) 1990-09-28
TW204344B (enExample) 1993-04-21
DD290188A5 (de) 1991-05-23
EP0317149A1 (en) 1989-05-24
BG50157A3 (bg) 1992-05-15
DE3866086D1 (de) 1991-12-12
ZA888241B (en) 1989-10-25
IL88358A (en) 1993-02-21
ES2038310T3 (es) 1993-07-16
US5011931A (en) 1991-04-30
NZ227008A (en) 1991-10-25
PT89024B (pt) 1993-02-26
IL88358A0 (en) 1989-06-30
PH27439A (en) 1993-07-02
FI91063C (fi) 1994-05-10
US5079264A (en) 1992-01-07
AU628305B2 (en) 1992-09-17
IE883366L (en) 1989-05-18

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