YU46989B - Postupak za dobijanje hinolonskih jedinjenja - Google Patents

Postupak za dobijanje hinolonskih jedinjenja

Info

Publication number
YU46989B
YU46989B YU209788A YU209788A YU46989B YU 46989 B YU46989 B YU 46989B YU 209788 A YU209788 A YU 209788A YU 209788 A YU209788 A YU 209788A YU 46989 B YU46989 B YU 46989B
Authority
YU
Yugoslavia
Prior art keywords
procedure
obtaining
quinolone compounds
compounds
quinolone
Prior art date
Application number
YU209788A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU209788A (en
Inventor
L. Mc Lean
D.L. Roberts
K. Barron
K.J. Nichol
Original Assignee
The Boots Co. Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Co. Plc. filed Critical The Boots Co. Plc.
Publication of YU209788A publication Critical patent/YU209788A/xx
Publication of YU46989B publication Critical patent/YU46989B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
YU209788A 1987-11-18 1988-11-11 Postupak za dobijanje hinolonskih jedinjenja YU46989B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878726950A GB8726950D0 (en) 1987-11-18 1987-11-18 Chemical process

Publications (2)

Publication Number Publication Date
YU209788A YU209788A (en) 1990-08-31
YU46989B true YU46989B (sh) 1994-09-09

Family

ID=10627131

Family Applications (1)

Application Number Title Priority Date Filing Date
YU209788A YU46989B (sh) 1987-11-18 1988-11-11 Postupak za dobijanje hinolonskih jedinjenja

Country Status (28)

Country Link
US (2) US5011931A (enExample)
EP (2) EP0343206A1 (enExample)
JP (1) JPH02502013A (enExample)
KR (1) KR890701563A (enExample)
AT (1) ATE69221T1 (enExample)
AU (1) AU628305B2 (enExample)
BG (1) BG50157A3 (enExample)
CS (1) CS274487B2 (enExample)
DD (1) DD290188A5 (enExample)
DE (1) DE3866086D1 (enExample)
ES (1) ES2038310T3 (enExample)
FI (1) FI91063C (enExample)
GB (1) GB8726950D0 (enExample)
GR (1) GR3003378T3 (enExample)
HU (1) HU204511B (enExample)
IE (1) IE883366L (enExample)
IL (1) IL88358A (enExample)
MX (1) MX168918B (enExample)
NZ (1) NZ227008A (enExample)
PH (1) PH27439A (enExample)
PL (1) PL157191B1 (enExample)
PT (1) PT89024B (enExample)
RO (1) RO104615B1 (enExample)
SU (1) SU1766255A3 (enExample)
TW (1) TW204344B (enExample)
WO (1) WO1989004827A1 (enExample)
YU (1) YU46989B (enExample)
ZA (1) ZA888241B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
US6132757A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6426084B1 (en) * 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6132753A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6194433B1 (en) 1998-10-05 2001-02-27 Neal R. Cutler Sexual dysfunction in females
US6110489A (en) * 1998-05-01 2000-08-29 Cutler; Neal R. Use of quinolines and quinolones to treat male erectile dysfunction
US6303135B1 (en) 1999-07-08 2001-10-16 Neal R. Cutler Use of quinolines and quinolones to treat male erectile dysfunction
US6307050B1 (en) * 2000-08-29 2001-10-23 R. T. Alamo Venture I Llc Method of synthesizing flosequinan from 4-fluoroanthranilic acid
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6531603B1 (en) 2001-06-29 2003-03-11 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6660864B2 (en) 2001-06-29 2003-12-09 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6657061B2 (en) 2001-06-29 2003-12-02 Grayson Walker Stowell Polymorphic forms of 6-[4-1(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6596871B2 (en) 2001-06-29 2003-07-22 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1h-tetraol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6388080B1 (en) 2001-06-29 2002-05-14 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
US6573382B2 (en) 2001-06-29 2003-06-03 Grayson Walker Stowell Polymorphic forms of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US6649764B2 (en) 2001-10-25 2003-11-18 R. T. Alamo Ventures I, Llc Stereospecific enrichment of heterocyclic enantiomers
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US6730790B2 (en) * 2002-03-01 2004-05-04 R.T. Alamo Ventures I. Llc Chlorinated heterocyclic compounds and methods of synthesis
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
KR20190116576A (ko) 2009-05-06 2019-10-14 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920699A (en) * 1974-04-26 1975-11-18 Warner Lambert Co Process for the cyclization of aryl(methylsulfinyl)-methyl ketones and compounds produced thereby
US4192873A (en) * 1976-11-25 1980-03-11 Ciba-Geigy Corporation Anti-inflammatory 2-sulphonyl- (or -sulphinyl)-2'-aminoacetophenones
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
FR2532939A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, les compositions les renfermant et les nouveaux intermediaires obtenus
EP0149519B1 (en) * 1984-01-13 1990-06-27 The Boots Company PLC Use of quinolones for the manufacture of a composition for the treatment of heart failure.
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8627698D0 (en) * 1986-11-20 1986-12-17 Boots Co Plc Therapeutic agents
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process

Also Published As

Publication number Publication date
IL88358A0 (en) 1989-06-30
HU204511B (en) 1992-01-28
MX168918B (es) 1993-06-14
NZ227008A (en) 1991-10-25
EP0317149A1 (en) 1989-05-24
RO104615B1 (en) 1992-11-03
JPH02502013A (ja) 1990-07-05
PL157191B1 (pl) 1992-05-29
FI893405L (fi) 1989-07-13
KR890701563A (ko) 1989-12-21
ATE69221T1 (de) 1991-11-15
PL275880A1 (en) 1989-06-12
ZA888241B (en) 1989-10-25
SU1766255A3 (ru) 1992-09-30
AU628305B2 (en) 1992-09-17
AU2616388A (en) 1989-06-14
YU209788A (en) 1990-08-31
TW204344B (enExample) 1993-04-21
GB8726950D0 (en) 1987-12-23
IL88358A (en) 1993-02-21
DD290188A5 (de) 1991-05-23
CS274487B2 (en) 1991-04-11
WO1989004827A1 (en) 1989-06-01
DE3866086D1 (de) 1991-12-12
FI91063B (fi) 1994-01-31
PT89024A (pt) 1988-12-01
GR3003378T3 (en) 1993-02-17
PT89024B (pt) 1993-02-26
HUT53085A (en) 1990-09-28
EP0343206A1 (en) 1989-11-29
FI91063C (fi) 1994-05-10
BG50157A3 (bg) 1992-05-15
ES2038310T3 (es) 1993-07-16
IE883366L (en) 1989-05-18
US5079264A (en) 1992-01-07
EP0317149B1 (en) 1991-11-06
FI893405A0 (fi) 1989-07-13
PH27439A (en) 1993-07-02
US5011931A (en) 1991-04-30
CS748988A2 (en) 1990-09-12

Similar Documents

Publication Publication Date Title
YU46989B (sh) Postupak za dobijanje hinolonskih jedinjenja
YU25497A (sh) Postupak za dobijanje sildenafila
ES482089A1 (es) Un procedimiento para la preparacion de octahidro pirazolo- (3,4-g) aminolinas.
EP0302525A3 (en) Quinolones as antibacterial agents
NO862426D0 (no) Fremgangsmaate for fremstilling av pyridobenzoksazinderivater.
FI881825A7 (fi) Uusien heterobisyklisten kinolonijohdannaisten valmistus.
ATE44954T1 (de) Carbostyrilderivat und verfahren zu seiner herstellung.
NO871727D0 (no) Fremgangsmaate for fremstilling av nye kinolinderivater.
MY102277A (en) Quinoline compounds
PT83104B (en) Novel guanidinomethylbenzoic acid derivatives
FR2453175A1 (fr) Trans-5-aryl-2,3,4,4a-5-9b-hexahydro-1h-pyrido(4,3-b)-indoles dextrogyres
PT83423A (en) Process for preparation of new quinoline derivatives
ES8606282A1 (es) Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
GR3004353T3 (enExample)
DK195685D0 (da) N-substituerede neuraminsyrederivater og fremgangsmaade til fremstilling af samme
GR1000355B (el) Μεθοδος παρασκευης 2-υποκατεστημενων ν,ν-διτριμεθοξυβενζουλοπιπεραζινων.
YU31995A (sh) Benzotiofeni glikopiranozida, postupak za njihovo dobijanje i njihova farmaceutska formulacija
GR900100112A (el) Μεθοδος παρασκευης ενωσεων πυριμιδο-πυριμιδινης αναστολεων της λιποξυγενασης.
IE853019L (en) A method for the preparation of derivatives of¹pyridine, quinoline and imidazoline¹unsubstituted 2-carbamoyl nicotinic and¹3-quinolinecarboxylic acids of formula (1).
ES459494A1 (es) Procedimiento de preparacion de hidrox-alfa-aminobencilpeni-cilina.
FR2367763A1 (fr) Nouvelles ( ( ( (phenyl substitue)-5 oxazolyl-2)methylene)
BG28414A4 (bg) Метод за получаване на 1-хидрокси-тетрахидробензо(с)хинолинони
IN167926B (enExample)
MY106512A (en) Process for the preparation of 6-(substitutedaminopro- pionyl)-derivatives of fokskolin.
JPS5412385A (en) Carbostyril derivative