YU45348B - Process for preaparation of resorufine derivatives - Google Patents

Process for preaparation of resorufine derivatives

Info

Publication number
YU45348B
YU45348B YU1302/86A YU130286A YU45348B YU 45348 B YU45348 B YU 45348B YU 1302/86 A YU1302/86 A YU 1302/86A YU 130286 A YU130286 A YU 130286A YU 45348 B YU45348 B YU 45348B
Authority
YU
Yugoslavia
Prior art keywords
carboxamido
cyano
carboxyl
case
derivatives
Prior art date
Application number
YU1302/86A
Other languages
English (en)
Other versions
YU130286A (en
Inventor
C Klein
H G Batz
R Hermann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of YU130286A publication Critical patent/YU130286A/xx
Publication of YU45348B publication Critical patent/YU45348B/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38[b, e]-condensed with two six-membered rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/802Chromogenic or luminescent peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
YU1302/86A 1985-07-25 1986-07-21 Process for preaparation of resorufine derivatives YU45348B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853526565 DE3526565A1 (de) 1985-07-25 1985-07-25 Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays

Publications (2)

Publication Number Publication Date
YU130286A YU130286A (en) 1987-12-31
YU45348B true YU45348B (en) 1992-05-28

Family

ID=6276697

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1302/86A YU45348B (en) 1985-07-25 1986-07-21 Process for preaparation of resorufine derivatives

Country Status (11)

Country Link
US (2) US4954630A (xx)
EP (1) EP0209875B1 (xx)
JP (3) JPS6236368A (xx)
KR (1) KR870001184A (xx)
AT (1) ATE55998T1 (xx)
CA (1) CA1338320C (xx)
CS (1) CS273617B2 (xx)
DE (2) DE3526565A1 (xx)
ES (1) ES2002110A6 (xx)
SU (1) SU1621811A3 (xx)
YU (1) YU45348B (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0319620A1 (en) * 1987-12-10 1989-06-14 Viomedics Inc. Novel oxazines-ureas and thiazine urea chromophors
DE3526565A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays
DE3644401A1 (de) * 1986-12-24 1988-07-07 Boehringer Mannheim Gmbh Neue hydrolase-substrate
JPH01211595A (ja) * 1988-02-18 1989-08-24 Kikkoman Corp 新規N−アセチル−β−D−グルコサミン誘導体、その製法及びN−アセチル−β−D−グルコサミニダーゼ活性測定用試薬への利用
AU6351896A (en) * 1995-07-26 1997-02-26 Universite De Montreal Elisa serodiagnosis of pig pleuropneumonia serotypes 5a and 5b
DE69836396T2 (de) 1997-04-08 2007-09-27 Université de Montreal, Montreal ELISA-Serodiagnose von Schweinepleuropneumonie des Serotyps 2
JP3810035B2 (ja) 1997-09-08 2006-08-16 日本精機株式会社 易開封性包装袋およびその製造装置
EP1140888B1 (en) * 1998-12-14 2003-05-14 Vertex Pharmaceuticals (San Diego) LLC Optical molecular sensors for cytochrome p450 activity
US6420130B1 (en) * 1998-12-14 2002-07-16 Aurora Biosciences Corporation Optical molecular sensors for cytochrome P450 activity
US6143492A (en) * 1998-12-14 2000-11-07 Aurora Biosciences Corporation Optical molecular sensors for cytochrome P450 activity
US6514687B1 (en) 1998-12-14 2003-02-04 Vertex Pharmaceuticals (San Diego), Llc Optical molecular sensors for cytochrome P450 activity
GB9902068D0 (en) * 1999-01-29 1999-03-24 Smithkline Beecham Plc Compounds
US6727356B1 (en) * 1999-12-08 2004-04-27 Epoch Pharmaceuticals, Inc. Fluorescent quenching detection reagents and methods
US20040081959A9 (en) 1999-12-08 2004-04-29 Epoch Biosciences, Inc. Fluorescent quenching detection reagents and methods
US6972339B2 (en) * 2001-09-07 2005-12-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
US8569516B2 (en) * 2001-09-07 2013-10-29 Elitech Holding B.V. Compounds and methods for fluorescent labeling
WO2004026804A1 (en) * 2002-09-20 2004-04-01 Integrated Dna Technologies, Inc. Anthraquinone quencher dyes, their methods of preparation and use
WO2005040357A2 (en) * 2003-10-24 2005-05-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
EP2298312B1 (en) 2003-10-31 2018-09-26 Molecular Probes Inc. Fluorinated resorufin compounds and their application in detecting hydrogen peroxide
US7439341B2 (en) 2003-11-14 2008-10-21 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
US7671218B2 (en) 2004-08-13 2010-03-02 Elitech Holdings B.V. Phosphonate fluorescent dyes and conjugates
EP1907560B1 (en) 2005-05-20 2013-01-23 Integrated DNA Technologies, Inc. Compounds and methods for labeling oligonucleotides
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
JP5886828B2 (ja) 2010-03-26 2016-03-16 インテグレイテッド ディーエヌエイ テクノロジーズ インコーポレイテッド 核酸のハイブリダイゼーションを強化する方法
US8735575B2 (en) 2010-07-30 2014-05-27 Washington University Phenoxazine derivatives and methods of use thereof
WO2012033848A1 (en) 2010-09-07 2012-03-15 Integrated Dna Technologies, Inc. Modifications for antisense compounds
DK2714939T3 (en) 2011-05-24 2015-06-29 Elitech Holding Bv DETECTION OF METHICILLIN-RESISTENT STAPHYLOCOCCUS AUREUS
US20140220598A1 (en) 2011-09-09 2014-08-07 Tohoku University Biological substance detection method
US9642858B2 (en) 2012-10-30 2017-05-09 University of Pittsburgh—of the Commonwealth System of Higher Education Use of resazurin, or analogs thereof, for antibacterial therapy
US20140255928A1 (en) 2013-03-11 2014-09-11 Elitech Holding B.V. Methods for true isothermal strand displacement amplification
WO2014186147A2 (en) 2013-05-13 2014-11-20 Elitech Holding B.V. Droplet digital pcr with short minor groove probes
WO2016094607A2 (en) 2014-12-12 2016-06-16 Elitechgroup B.V. Methods and compositions for detecting antibiotic resistant bacteria
US10266903B2 (en) 2014-12-12 2019-04-23 Elitechgroup, Inc. Methods and compositions for detecting antibiotic resistant bacteria
WO2021080629A1 (en) 2019-10-23 2021-04-29 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
EP3932995A1 (en) 2020-07-04 2022-01-05 Emulseo SAS Novel fluorescent substrates and uses thereof in microfluidics

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB807687A (en) * 1955-10-10 1959-01-21 Bayer Ag Phenoxazone-dicarboxylic acid derivatives
US4141688A (en) * 1977-08-11 1979-02-27 Miles Laboratories, Inc. Composition, device and method for determining reducing agents
IT1140209B (it) * 1981-09-25 1986-09-24 Anic Spa Reagenti per immunoluorescenza e metodo per la loro preparazione
US4667032A (en) * 1983-01-21 1987-05-19 Merck Frosst Canada, Inc. Phenothiazone derivatives and analogs
US4859667A (en) * 1983-01-21 1989-08-22 Merck Frosst Canada, Inc. Pharmaceutical compositions of phenothiazone derivatives and analogs
US4714763A (en) * 1985-07-11 1987-12-22 Viomedics Inc. Novel oxazine-ureas and thiazine urea chromophors as fluorescent labels
DE3526566A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh N-acyl-dihydroresorufin-derivate, verfahren zu deren herstellung sowie deren verwendung zur bestimmung von wasserstoffperoxid, peroxidatisch wirkender verbindungen oder peroxidase
DE3526565A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays
DE3644401A1 (de) * 1986-12-24 1988-07-07 Boehringer Mannheim Gmbh Neue hydrolase-substrate
US5242805A (en) * 1991-08-23 1993-09-07 Molecular Probes, Inc. Long wavelength lipophilic fluorogenic glycosidase substrates

Also Published As

Publication number Publication date
ATE55998T1 (de) 1990-09-15
EP0209875B1 (de) 1990-08-29
DE3673715D1 (de) 1990-10-04
JPS62174066A (ja) 1987-07-30
EP0209875A1 (de) 1987-01-28
CS273617B2 (en) 1991-03-12
ES2002110A6 (es) 1988-07-16
CA1338320C (en) 1996-05-07
CS549286A2 (en) 1990-08-14
YU130286A (en) 1987-12-31
US5304645A (en) 1994-04-19
KR870001184A (ko) 1987-03-12
US4954630A (en) 1990-09-04
SU1621811A3 (ru) 1991-01-15
JPS6236368A (ja) 1987-02-17
DE3526565A1 (de) 1987-02-05
JPS62174067A (ja) 1987-07-30

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