CS273617B2 - Method of resorufine's derivatives production - Google Patents

Method of resorufine's derivatives production Download PDF

Info

Publication number
CS273617B2
CS273617B2 CS549286A CS549286A CS273617B2 CS 273617 B2 CS273617 B2 CS 273617B2 CS 549286 A CS549286 A CS 549286A CS 549286 A CS549286 A CS 549286A CS 273617 B2 CS273617 B2 CS 273617B2
Authority
CS
Czechoslovakia
Prior art keywords
group
carboxylic acid
hydroxysuccinimide
substituted
amino
Prior art date
Application number
CS549286A
Other languages
Czech (cs)
English (en)
Other versions
CS549286A2 (en
Inventor
Christian Dr Klein
Hans-Georg Dr Batz
Rupert Dr Herrmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Priority to CS104187A priority Critical patent/CS273630B2/cs
Publication of CS549286A2 publication Critical patent/CS549286A2/cs
Publication of CS273617B2 publication Critical patent/CS273617B2/cs

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38—[b, e]-condensed with two six-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/802—Chromogenic or luminescent peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS549286A 1985-07-25 1986-07-18 Method of resorufine's derivatives production CS273617B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS104187A CS273630B2 (en) 1985-07-25 1987-02-17 Method of resorufine's derivatives production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853526565 DE3526565A1 (de) 1985-07-25 1985-07-25 Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays

Publications (2)

Publication Number Publication Date
CS549286A2 CS549286A2 (en) 1990-08-14
CS273617B2 true CS273617B2 (en) 1991-03-12

Family

ID=6276697

Family Applications (1)

Application Number Title Priority Date Filing Date
CS549286A CS273617B2 (en) 1985-07-25 1986-07-18 Method of resorufine's derivatives production

Country Status (11)

Country Link
US (2) US4954630A (xx)
EP (1) EP0209875B1 (xx)
JP (3) JPS6236368A (xx)
KR (1) KR870001184A (xx)
AT (1) ATE55998T1 (xx)
CA (1) CA1338320C (xx)
CS (1) CS273617B2 (xx)
DE (2) DE3526565A1 (xx)
ES (1) ES2002110A6 (xx)
SU (1) SU1621811A3 (xx)
YU (1) YU45348B (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0319620A1 (en) * 1987-12-10 1989-06-14 Viomedics Inc. Novel oxazines-ureas and thiazine urea chromophors
DE3526565A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays
DE3644401A1 (de) * 1986-12-24 1988-07-07 Boehringer Mannheim Gmbh Neue hydrolase-substrate
JPH01211595A (ja) * 1988-02-18 1989-08-24 Kikkoman Corp 新規Ｎ−アセチル−β−Ｄ−グルコサミン誘導体、その製法及びＮ−アセチル−β−Ｄ−グルコサミニダーゼ活性測定用試薬への利用
WO1997005487A1 (en) * 1995-07-26 1997-02-13 Universite De Montreal ELISA SERODIAGNOSIS OF PIG PLEUROPNEUMONIA SEROTYPES 5a AND 5b
ES2277376T3 (es) 1997-04-08 2007-07-01 Universite De Montreal Serodiagnostico mediante elisa de la pleuroneumonia porcina de serotipo 2.
JP3810035B2 (ja) 1997-09-08 2006-08-16 日本精機株式会社 易開封性包装袋およびその製造装置
US6514687B1 (en) 1998-12-14 2003-02-04 Vertex Pharmaceuticals (San Diego), Llc Optical molecular sensors for cytochrome P450 activity
CA2352631A1 (en) * 1998-12-14 2000-06-22 Aurora Biosciences Corporation Optical molecular sensors for cytochrome p450 activity
US6143492A (en) * 1998-12-14 2000-11-07 Aurora Biosciences Corporation Optical molecular sensors for cytochrome P450 activity
US6420130B1 (en) * 1998-12-14 2002-07-16 Aurora Biosciences Corporation Optical molecular sensors for cytochrome P450 activity
GB9902068D0 (en) * 1999-01-29 1999-03-24 Smithkline Beecham Plc Compounds
US6727356B1 (en) * 1999-12-08 2004-04-27 Epoch Pharmaceuticals, Inc. Fluorescent quenching detection reagents and methods
US20040081959A9 (en) * 1999-12-08 2004-04-29 Epoch Biosciences, Inc. Fluorescent quenching detection reagents and methods
US8569516B2 (en) * 2001-09-07 2013-10-29 Elitech Holding B.V. Compounds and methods for fluorescent labeling
US6972339B2 (en) 2001-09-07 2005-12-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
US7803536B2 (en) * 2002-09-20 2010-09-28 Integrated Dna Technologies, Inc. Methods of detecting fluorescence with anthraquinone quencher dyes
US7541454B2 (en) * 2003-10-24 2009-06-02 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
WO2005042504A1 (en) * 2003-10-31 2005-05-12 Molecular Probes, Inc. Fluorinated resorufin compounds and their application in detecting hydrogen peroxide
US7439341B2 (en) 2003-11-14 2008-10-21 Integrated Dna Technologies, Inc. Fluorescence quenching azo dyes, their methods of preparation and use
ES2461858T3 (es) 2004-08-13 2014-05-21 Epoch Biosciences, Inc. Colorantes fluorescentes de fosfonato y conjugados
CA2601554A1 (en) * 2005-05-20 2006-11-30 Integrated Dna Technologies, Inc. Compounds and methods for labeling oligonucleotides
WO2011120049A1 (en) * 2010-03-26 2011-09-29 Integrated Dna Technologies, Inc. Methods for enhancing nucleic acid hybridization
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
US8735575B2 (en) 2010-07-30 2014-05-27 Washington University Phenoxazine derivatives and methods of use thereof
EP2896696B1 (en) 2010-09-07 2017-12-27 Integrated Dna Technologies, Inc. Modifications for antisense compounds
DK2714939T3 (en) 2011-05-24 2015-06-29 Elitech Holding Bv DETECTION OF METHICILLIN-RESISTENT STAPHYLOCOCCUS AUREUS
JP5812095B2 (ja) 2011-09-09 2015-11-11 コニカミノルタ株式会社 生体物質検出方法
WO2014070760A1 (en) 2012-10-30 2014-05-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of resazurin, or analogs thereof, for antibacterial therapy
WO2014164479A1 (en) 2013-03-11 2014-10-09 Elitech Holding B.V. Methods for true isothermal strand displacement amplification
WO2014186147A2 (en) 2013-05-13 2014-11-20 Elitech Holding B.V. Droplet digital pcr with short minor groove probes
JP2017538418A (ja) 2014-12-12 2017-12-28 エリテックグループ・ベスローテン・フェンノートシャップＥｌｉｔｅｃｈｇｒｏｕｐ Ｂ．Ｖ． 抗生物質耐性細菌を検出する方法および組成物
JP2017538419A (ja) 2014-12-12 2017-12-28 エリテックグループ・ベスローテン・フェンノートシャップＥｌｉｔｅｃｈｇｒｏｕｐ Ｂ．Ｖ． 抗生物質耐性菌を検出するための方法および組成物
WO2021080629A1 (en) 2019-10-23 2021-04-29 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
EP3932995A1 (en) 2020-07-04 2022-01-05 Emulseo SAS Novel fluorescent substrates and uses thereof in microfluidics

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB807687A (en) * 1955-10-10 1959-01-21 Bayer Ag Phenoxazone-dicarboxylic acid derivatives
US4141688A (en) * 1977-08-11 1979-02-27 Miles Laboratories, Inc. Composition, device and method for determining reducing agents
IT1140209B (it) * 1981-09-25 1986-09-24 Anic Spa Reagenti per immunoluorescenza e metodo per la loro preparazione
US4667032A (en) * 1983-01-21 1987-05-19 Merck Frosst Canada, Inc. Phenothiazone derivatives and analogs
US4859667A (en) * 1983-01-21 1989-08-22 Merck Frosst Canada, Inc. Pharmaceutical compositions of phenothiazone derivatives and analogs
US4714763A (en) * 1985-07-11 1987-12-22 Viomedics Inc. Novel oxazine-ureas and thiazine urea chromophors as fluorescent labels
DE3526565A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh Resorufin-derivate, verfahren zu deren herstellung sowie deren verwendung in fluoreszenzimmunoassays
DE3526566A1 (de) * 1985-07-25 1987-02-05 Boehringer Mannheim Gmbh N-acyl-dihydroresorufin-derivate, verfahren zu deren herstellung sowie deren verwendung zur bestimmung von wasserstoffperoxid, peroxidatisch wirkender verbindungen oder peroxidase
DE3644401A1 (de) * 1986-12-24 1988-07-07 Boehringer Mannheim Gmbh Neue hydrolase-substrate
US5242805A (en) * 1991-08-23 1993-09-07 Molecular Probes, Inc. Long wavelength lipophilic fluorogenic glycosidase substrates

Also Published As

Publication number Publication date
YU130286A (en) 1987-12-31
ES2002110A6 (es) 1988-07-16
EP0209875B1 (de) 1990-08-29
DE3673715D1 (de) 1990-10-04
CA1338320C (en) 1996-05-07
US4954630A (en) 1990-09-04
DE3526565A1 (de) 1987-02-05
JPS6236368A (ja) 1987-02-17
SU1621811A3 (ru) 1991-01-15
JPS62174066A (ja) 1987-07-30
JPS62174067A (ja) 1987-07-30
YU45348B (en) 1992-05-28
CS549286A2 (en) 1990-08-14
US5304645A (en) 1994-04-19
EP0209875A1 (de) 1987-01-28
KR870001184A (ko) 1987-03-12
ATE55998T1 (de) 1990-09-15

Similar Documents

Publication Publication Date Title
CS273617B2 (en) Method of resorufine's derivatives production
US9212385B2 (en) Fluorinated resorufin compounds and their application
AU717569B2 (en) Fluorinated xanthene derivatives
US5696157A (en) Sulfonated derivatives of 7-aminocoumarin
EP0321353B1 (fr) Cryptates de terres rares, procédés d'obtention, intermédiaires de synthèse et application à titre de marqueurs fluorescents
US20050123935A1 (en) Pyrenyloxysulfonic acid fluorescent agents
US9513284B2 (en) Pyrenyloxysulfonic acid fluorescent agents
WO2004027388A2 (en) Novel green and orange fluorescent labels and their uses
US5981747A (en) Monomethine cyanines rigidized by a two-carbon chain
JP4098839B2 (ja) インドシアニン化合物
CS273630B2 (en) Method of resorufine's derivatives production