YU41319B - Process for obtaining products of the selective hydrogenation of c-076 compounds - Google Patents

Process for obtaining products of the selective hydrogenation of c-076 compounds

Info

Publication number
YU41319B
YU41319B YU2319/78A YU231978A YU41319B YU 41319 B YU41319 B YU 41319B YU 2319/78 A YU2319/78 A YU 2319/78A YU 231978 A YU231978 A YU 231978A YU 41319 B YU41319 B YU 41319B
Authority
YU
Yugoslavia
Prior art keywords
compounds
selective hydrogenation
obtaining products
obtaining
products
Prior art date
Application number
YU2319/78A
Other languages
English (en)
Other versions
YU231978A (en
Inventor
J C Chabala
M H Fischer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25277555&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU41319(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to SI7812319A priority Critical patent/SI7812319A8/sl
Publication of YU231978A publication Critical patent/YU231978A/xx
Publication of YU41319B publication Critical patent/YU41319B/xx
Priority to HR940102A priority patent/HRP940102B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU2319/78A 1977-10-03 1978-10-02 Process for obtaining products of the selective hydrogenation of c-076 compounds YU41319B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI7812319A SI7812319A8 (sl) 1977-10-03 1978-10-02 Postopek za pripravo makrolidnih spojin.
HR940102A HRP940102B1 (en) 1977-10-03 1994-02-14 Process for the preparation of macrolyde compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83860377A 1977-10-03 1977-10-03

Publications (2)

Publication Number Publication Date
YU231978A YU231978A (en) 1983-01-21
YU41319B true YU41319B (en) 1987-02-28

Family

ID=25277555

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2319/78A YU41319B (en) 1977-10-03 1978-10-02 Process for obtaining products of the selective hydrogenation of c-076 compounds

Country Status (27)

Country Link
EP (1) EP0001689B1 (es)
JP (1) JPS5461198A (es)
AT (1) AT366690B (es)
AU (1) AU519569B2 (es)
BG (1) BG34340A3 (es)
CS (1) CS207678B2 (es)
DD (1) DD140458A5 (es)
DE (1) DE2862390D1 (es)
DK (1) DK152128C (es)
ES (1) ES473926A1 (es)
FI (1) FI67857C (es)
GR (1) GR64919B (es)
GT (1) GT197854449A (es)
HU (1) HU179244B (es)
IE (1) IE48032B1 (es)
IL (1) IL55603A (es)
IT (1) IT1107561B (es)
NL (1) NL930116I1 (es)
NO (1) NO149662C (es)
NZ (1) NZ188460A (es)
OA (1) OA06064A (es)
PH (1) PH15982A (es)
PL (1) PL115455B1 (es)
PT (1) PT68580A (es)
RO (1) RO75612A (es)
YU (1) YU41319B (es)
ZM (1) ZM8278A1 (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4550160A (en) * 1979-08-13 1985-10-29 Merck & Co., Inc. Processes for the interconversion of C-076 compounds
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
ATE21984T1 (de) * 1981-10-06 1986-09-15 Ici Plc Verfahren zur bekaempfung von nematodenschaedlingen der pflanzen und zusammensetzungen dafuer.
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
RU2024527C1 (ru) * 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ES2045146T3 (es) * 1987-11-09 1994-01-16 Pfizer Avermectinas etiladas.
US4963667A (en) * 1987-11-10 1990-10-16 Merck & Co., Inc. Ivermectin derivative compounds and process for preparing the same
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
CA1339481C (en) * 1988-10-18 1997-09-30 Shieh-Shung Tom Chen Anthelmintic bioconversion products
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
US5380838A (en) * 1993-10-08 1995-01-10 Merck & Co. Inc. Stable solvates of avermectin compounds
DE19507018A1 (de) * 1995-03-01 1996-09-05 Bayer Ag Verfahren zur Herstellung von Ivermectin
WO1997046204A2 (en) 1996-06-05 1997-12-11 Ashmont Holdings Limited Injectable compositions
DE19644050A1 (de) * 1996-10-31 1998-05-07 Bayer Ag Verfahren zur Herstellung von Ivermectin
US7001889B2 (en) 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2127522A1 (de) 2008-05-29 2009-12-02 Bayer CropScience AG Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
EP2382865A1 (de) 2010-04-28 2011-11-02 Bayer CropScience AG Synergistische Wirkstoffkombinationen
JPWO2014017319A1 (ja) 2012-07-26 2016-07-11 国立大学法人京都大学 フィラグリン産生促進剤、フィラグリン産生低下に伴う疾患治療剤及び当該治療剤のスクリーニング方法
EP4062907A1 (fr) 2021-03-23 2022-09-28 Substipharm Formulation par voie orale d'ivermectine et utilisations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (es) * 1972-06-08 1974-02-08
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis

Also Published As

Publication number Publication date
IT1107561B (it) 1985-11-25
DK434578A (da) 1979-04-04
NO783307L (no) 1979-04-04
RO75612A (ro) 1981-01-30
AU3999678A (en) 1980-03-27
NL930116I1 (nl) 1993-10-18
IL55603A0 (en) 1978-12-17
IE781963L (en) 1979-04-03
FI67857B (fi) 1985-02-28
DK152128C (da) 1988-06-20
IE48032B1 (en) 1984-09-05
JPS5461198A (en) 1979-05-17
ATA711378A (de) 1981-09-15
EP0001689A1 (en) 1979-05-02
NO149662B (no) 1984-02-20
JPH0317837B2 (es) 1991-03-11
DD140458A5 (de) 1980-03-05
YU231978A (en) 1983-01-21
AU519569B2 (en) 1981-12-10
EP0001689B1 (en) 1984-03-21
PL115455B1 (en) 1981-04-30
CS207678B2 (en) 1981-08-31
BG34340A3 (en) 1983-08-15
DE2862390D1 (en) 1984-04-26
NO149662C (no) 1984-05-30
IT7851277A0 (it) 1978-09-27
PT68580A (en) 1978-10-01
FI782880A (fi) 1979-04-04
FI67857C (fi) 1985-06-10
IL55603A (en) 1982-07-30
ES473926A1 (es) 1980-01-16
PH15982A (en) 1983-05-18
ZM8278A1 (en) 1980-07-21
GR64919B (en) 1980-06-09
OA06064A (fr) 1981-06-30
HU179244B (en) 1982-09-28
GT197854449A (es) 1980-03-25
PL210030A1 (pl) 1979-06-18
DK152128B (da) 1988-02-01
NZ188460A (en) 1980-05-08
AT366690B (de) 1982-04-26

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