YU34303A - Postupak za proizvodnju 4-(17alfa-supstituisani-3-oksoestra -4,9-dien-11beta-il)benzaldehid-(1e ili 1z)-oksima - Google Patents
Postupak za proizvodnju 4-(17alfa-supstituisani-3-oksoestra -4,9-dien-11beta-il)benzaldehid-(1e ili 1z)-oksimaInfo
- Publication number
- YU34303A YU34303A YU34303A YUP34303A YU34303A YU 34303 A YU34303 A YU 34303A YU 34303 A YU34303 A YU 34303A YU P34303 A YUP34303 A YU P34303A YU 34303 A YU34303 A YU 34303A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- oxoestra
- benzaldehyd
- dien
- oximes
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Epoxy Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Studio Devices (AREA)
Abstract
Pronalazak se odnosi na postupak za proizvodnju 4-(17α-supstituisanih-3-oksoestra-4,9-dien-11ГЎ-il)benzaldehid-(1E ili 1Z)-oksima opšte formule (I), gde je R1=H, C1-6alkil ili CnF2n+1 grupa; R2 = C1-4alkil, X= E- ili Z-OH; a Y=O-C1-6 alkil, S-C1-6 alkil ili O-CH2CNF2n+1, pri čemu n=1, 2 ili 3, koji proizvodi cijana jedinjenja formule (I) sa visokim prinosom i selektivnošću.[The invention relates to a method for the production of 4-(17α substituted 3-oxoestra-4,9-dien-11ГЎ-yl)benzaldehyd-(1E or 1Z)- oximes of general formula (I), where R1 = H, C1-6 alkyl or a CnF2n+1 group; R2 = C1- 4 alkyl, X = E- or Z-OH; and Y = O-C1-6 alkyl, S- C1-6 alkyl or O-CH2CnF2n+1, where n = 1, 2 or 3, which produces the target compounds of formula (I) with high yield and selectivity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10056676A DE10056676A1 (de) | 2000-11-10 | 2000-11-10 | Verfahren zur Herstellung von 4-/17alpha-substituierten-3-oxoestra-4,9-dien-11beta-yl)benzaldehyd-(1E oder 1Z)-oximen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU34303A true YU34303A (sh) | 2006-08-17 |
Family
ID=7663441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU34303A YU34303A (sh) | 2000-11-10 | 2001-11-09 | Postupak za proizvodnju 4-(17alfa-supstituisani-3-oksoestra -4,9-dien-11beta-il)benzaldehid-(1e ili 1z)-oksima |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7214808B2 (sh) |
| EP (1) | EP1339734B1 (sh) |
| JP (1) | JP4263478B2 (sh) |
| KR (1) | KR100836323B1 (sh) |
| CN (1) | CN100368427C (sh) |
| AT (1) | ATE337328T1 (sh) |
| AU (2) | AU2002216911B2 (sh) |
| BG (1) | BG107886A (sh) |
| BR (1) | BR0115249A (sh) |
| CA (1) | CA2427632C (sh) |
| CZ (1) | CZ301425B6 (sh) |
| DE (2) | DE10056676A1 (sh) |
| EA (1) | EA005530B1 (sh) |
| EE (1) | EE200300222A (sh) |
| HK (1) | HK1063187A1 (sh) |
| HR (1) | HRP20030458A2 (sh) |
| HU (1) | HUP0301765A2 (sh) |
| IL (2) | IL155680A0 (sh) |
| MX (1) | MXPA03004109A (sh) |
| NO (1) | NO20032080D0 (sh) |
| NZ (1) | NZ525962A (sh) |
| PL (1) | PL205091B1 (sh) |
| SK (1) | SK286601B6 (sh) |
| WO (1) | WO2002038582A2 (sh) |
| YU (1) | YU34303A (sh) |
| ZA (1) | ZA200304480B (sh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006018888A1 (de) * | 2006-04-18 | 2007-10-25 | Bayer Schering Pharma Ag | Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil) |
| JP4843372B2 (ja) * | 2006-05-09 | 2011-12-21 | 株式会社リコー | 画像処理装置 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4332284C2 (de) * | 1993-09-20 | 1997-05-28 | Jenapharm Gmbh | 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE4332283A1 (de) * | 1993-09-20 | 1995-04-13 | Jenapharm Gmbh | Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US5576310A (en) * | 1994-09-20 | 1996-11-19 | Jenapharm Gmbh | 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds |
-
2000
- 2000-11-10 DE DE10056676A patent/DE10056676A1/de not_active Withdrawn
-
2001
- 2001-11-09 MX MXPA03004109A patent/MXPA03004109A/es active IP Right Grant
- 2001-11-09 EE EEP200300222A patent/EE200300222A/xx unknown
- 2001-11-09 SK SK551-2003A patent/SK286601B6/sk not_active IP Right Cessation
- 2001-11-09 US US10/416,029 patent/US7214808B2/en not_active Expired - Lifetime
- 2001-11-09 CZ CZ20031282A patent/CZ301425B6/cs not_active IP Right Cessation
- 2001-11-09 KR KR1020037006317A patent/KR100836323B1/ko not_active IP Right Cessation
- 2001-11-09 PL PL361399A patent/PL205091B1/pl not_active IP Right Cessation
- 2001-11-09 AU AU2002216911A patent/AU2002216911B2/en not_active Ceased
- 2001-11-09 HU HU0301765A patent/HUP0301765A2/hu unknown
- 2001-11-09 CA CA2427632A patent/CA2427632C/en not_active Expired - Lifetime
- 2001-11-09 NZ NZ525962A patent/NZ525962A/en unknown
- 2001-11-09 AU AU1691102A patent/AU1691102A/xx active Pending
- 2001-11-09 EA EA200300506A patent/EA005530B1/ru not_active IP Right Cessation
- 2001-11-09 BR BR0115249-1A patent/BR0115249A/pt not_active IP Right Cessation
- 2001-11-09 AT AT01993608T patent/ATE337328T1/de not_active IP Right Cessation
- 2001-11-09 CN CNB018186785A patent/CN100368427C/zh not_active Expired - Fee Related
- 2001-11-09 JP JP2002541114A patent/JP4263478B2/ja not_active Expired - Fee Related
- 2001-11-09 YU YU34303A patent/YU34303A/sh unknown
- 2001-11-09 DE DE50110829T patent/DE50110829D1/de not_active Expired - Lifetime
- 2001-11-09 WO PCT/DE2001/004218 patent/WO2002038582A2/de active IP Right Grant
- 2001-11-09 EP EP01993608A patent/EP1339734B1/de not_active Expired - Lifetime
- 2001-11-09 IL IL15568001A patent/IL155680A0/xx unknown
-
2003
- 2003-04-30 IL IL155680A patent/IL155680A/en not_active IP Right Cessation
- 2003-05-09 NO NO20032080A patent/NO20032080D0/no unknown
- 2003-06-06 HR HR20030458A patent/HRP20030458A2/hr not_active Application Discontinuation
- 2003-06-06 BG BG107886A patent/BG107886A/bg unknown
- 2003-06-09 ZA ZA200304480A patent/ZA200304480B/en unknown
-
2004
- 2004-08-10 HK HK04105980A patent/HK1063187A1/xx not_active IP Right Cessation
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