YU30302A - Supstituisani norbornilamino-derivati, postupak za njihovu proizvodnju, njihova primena u svojstvu leka ili dijagnostičkog reagensa kao i lekovi koji sadrže jedinjenja - Google Patents
Supstituisani norbornilamino-derivati, postupak za njihovu proizvodnju, njihova primena u svojstvu leka ili dijagnostičkog reagensa kao i lekovi koji sadrže jedinjenjaInfo
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- YU30302A YU30302A YU30302A YUP30302A YU30302A YU 30302 A YU30302 A YU 30302A YU 30302 A YU30302 A YU 30302A YU P30302 A YUP30302 A YU P30302A YU 30302 A YU30302 A YU 30302A
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- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
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Abstract
Pronalazak se odnosi na supstituisane norbornilamino-derivate, koji sadrze egzokonfigurisani azot i endo-spojeni petoclani prsten Formule (I) i koji sadrze egzokonfigurisani azot i egzo-spojeni petoclani prsten Formule (Ia), u kojoj R1, R2, R3, R4, R5, A, B, S1 i S2 imaju znacenja navedena u patentnim zahtevima. Ovi derivati su narocito podesni kao sredstva protiv visokog krvnog pritiska, za smanjenje ili sprecavanje ostecenja prouzrokovanih ishemicnim stanjima, kao lekovi za operativne zahvate, za lecenje ishemija nervnog sistema, mozdanog udara i edema mozga, soka, ostecenog respiratornog nagona, za lecenje hrkanja, kao laksativ, kao sredstvo protiv ektoparazita, u predohrani stvaranja kamena u zuci, kao antiaterosklerotik, sredstvo protiv kasnijih komplikacija kod diabetesa, kancerogenoznih oboljenja, fibroznih oboljenja, endotelialne disfunkcije, hipertrofije i hiperplazije organa. Oni su inhibitori celijskog natrijum-proton-antiporta. Oni uticu na nivo lipoproteina u serumu i mogu zbog toga da se primene za profilaksu i za regresiju ateroskleroticnih promena.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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DE19960204A DE19960204A1 (de) | 1999-12-14 | 1999-12-14 | Substituierte Norlbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
Publication Number | Publication Date |
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YU30302A true YU30302A (sh) | 2005-06-10 |
Family
ID=7932583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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YU30302A YU30302A (sh) | 1999-12-14 | 2000-12-01 | Supstituisani norbornilamino-derivati, postupak za njihovu proizvodnju, njihova primena u svojstvu leka ili dijagnostičkog reagensa kao i lekovi koji sadrže jedinjenja |
Country Status (26)
Country | Link |
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US (1) | US6825231B2 (sh) |
EP (1) | EP1255724B1 (sh) |
JP (1) | JP2003517033A (sh) |
KR (1) | KR20030004308A (sh) |
CN (1) | CN1210251C (sh) |
AR (1) | AR032434A1 (sh) |
AT (1) | ATE338022T1 (sh) |
AU (1) | AU778888B2 (sh) |
BR (1) | BR0016360A (sh) |
CA (1) | CA2394130A1 (sh) |
CZ (1) | CZ20022006A3 (sh) |
DE (2) | DE19960204A1 (sh) |
EE (1) | EE200200292A (sh) |
HK (1) | HK1049655B (sh) |
HR (1) | HRP20020517A2 (sh) |
HU (1) | HUP0204360A3 (sh) |
IL (1) | IL150228A0 (sh) |
MX (1) | MXPA02003763A (sh) |
NO (1) | NO20022801L (sh) |
NZ (1) | NZ519511A (sh) |
PL (1) | PL356235A1 (sh) |
RU (1) | RU2260584C2 (sh) |
SK (1) | SK8202002A3 (sh) |
WO (1) | WO2001044164A1 (sh) |
YU (1) | YU30302A (sh) |
ZA (1) | ZA200204663B (sh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10063294A1 (de) | 2000-12-19 | 2002-07-04 | Aventis Pharma Gmbh | Substituierte Heterocyclo-Norbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE10156617A1 (de) | 2001-11-17 | 2003-05-28 | Biosphings Ag | Herstellung reiner Stereoisomere von Tricyclo[5.2.1.0··2··.··6··]-dec-9-yl-xanthogenat und Arzneimittel daraus |
US20030187045A1 (en) * | 2001-12-21 | 2003-10-02 | Uwe Heinelt | Substituted imidazolidines, process for their preparation, and their use as a medicament or diagnostic |
DE10163239A1 (de) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituierte Imidazolidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie enthaltendes Medikament |
DE10224892A1 (de) * | 2002-06-04 | 2003-12-18 | Aventis Pharma Gmbh | Substituierte Thiophene, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US7049333B2 (en) | 2002-06-04 | 2006-05-23 | Sanofi-Aventis Deutschland Gmbh | Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis |
US20050054705A1 (en) * | 2003-02-04 | 2005-03-10 | Aventis Pharma Deutschland Gmbh | N-substituted (benzoimidazol-2-yl) phenylamines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
DE10304374A1 (de) * | 2003-02-04 | 2004-08-05 | Aventis Pharma Deutschland Gmbh | Neue substituierte 2-Aminoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE102005001411A1 (de) | 2005-01-12 | 2006-07-27 | Sanofi-Aventis Deutschland Gmbh | Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament |
EP2170872B1 (en) | 2007-06-28 | 2010-09-01 | Sanofi-Aventis U.S. LLC | Process for the preparation of the n-(2-chloro-4-methyl-3-thienyl)-1h- benzimidazol-2-amine hydrochloride and intermediates thereof |
KR20110050718A (ko) | 2008-09-02 | 2011-05-16 | 사노피-아벤티스 | 치환된 아미노인단 및 그의 유사체, 및 그의 제약 용도 |
DE102009030291A1 (de) * | 2009-06-24 | 2011-01-05 | Cu Chemie Uetikon Gmbh | Enantiomerenreine tricyclische Verbindung und Verfahren zur diastereomerenreinen und enantiomerenreinen Herstellung bicyclischer und tricyclischer Verbindungen |
US9556322B2 (en) | 2013-08-13 | 2017-01-31 | Colormatrix Holdings, Inc. | Liquid pigment dispersions |
WO2023249027A1 (ja) * | 2022-06-20 | 2023-12-28 | 三菱ケミカル株式会社 | 第4級アンモニウム塩、有機構造規定剤、第4級アンモニウム塩の製造方法、con型ゼオライト、con型ゼオライトの製造方法、触媒および低級オレフィンの製造方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2403138A1 (de) * | 1974-01-23 | 1975-07-31 | Hoechst Ag | Benzylaminderivate und verfahren zu ihrer herstellung |
EP0556674B1 (de) * | 1992-02-15 | 1996-06-19 | Hoechst Aktiengesellschaft | 3,5-Substituierte Benzoylguanidine, mit antiarrythmischer Wirkung und inhibierender Wirkung auf die Proliferationen von Zellen |
DE19518073A1 (de) * | 1995-05-17 | 1996-11-21 | Hoechst Ag | Substituierte Benzyloxycarbonylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
DE19633966A1 (de) * | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1999
- 1999-12-14 DE DE19960204A patent/DE19960204A1/de not_active Withdrawn
-
2000
- 2000-12-01 YU YU30302A patent/YU30302A/sh unknown
- 2000-12-01 CZ CZ20022006A patent/CZ20022006A3/cs unknown
- 2000-12-01 AU AU15254/01A patent/AU778888B2/en not_active Ceased
- 2000-12-01 EP EP00977604A patent/EP1255724B1/de not_active Expired - Lifetime
- 2000-12-01 HU HU0204360A patent/HUP0204360A3/hu unknown
- 2000-12-01 JP JP2001545253A patent/JP2003517033A/ja active Pending
- 2000-12-01 WO PCT/EP2000/012107 patent/WO2001044164A1/de active Search and Examination
- 2000-12-01 DE DE50013410T patent/DE50013410D1/de not_active Expired - Lifetime
- 2000-12-01 KR KR1020027007555A patent/KR20030004308A/ko not_active Application Discontinuation
- 2000-12-01 IL IL15022800A patent/IL150228A0/xx unknown
- 2000-12-01 MX MXPA02003763A patent/MXPA02003763A/es active IP Right Grant
- 2000-12-01 RU RU2002118700/04A patent/RU2260584C2/ru not_active IP Right Cessation
- 2000-12-01 CN CNB008144648A patent/CN1210251C/zh not_active Expired - Fee Related
- 2000-12-01 CA CA002394130A patent/CA2394130A1/en not_active Abandoned
- 2000-12-01 SK SK820-2002A patent/SK8202002A3/sk unknown
- 2000-12-01 BR BR0016360-0A patent/BR0016360A/pt not_active IP Right Cessation
- 2000-12-01 NZ NZ519511A patent/NZ519511A/en unknown
- 2000-12-01 AT AT00977604T patent/ATE338022T1/de not_active IP Right Cessation
- 2000-12-01 EE EEP200200292A patent/EE200200292A/xx unknown
- 2000-12-01 PL PL00356235A patent/PL356235A1/xx not_active Application Discontinuation
- 2000-12-12 AR ARP000106577A patent/AR032434A1/es unknown
- 2000-12-12 US US09/734,008 patent/US6825231B2/en not_active Expired - Fee Related
-
2002
- 2002-06-11 ZA ZA200204663A patent/ZA200204663B/en unknown
- 2002-06-12 NO NO20022801A patent/NO20022801L/no not_active Application Discontinuation
- 2002-06-13 HR HR20020517A patent/HRP20020517A2/hr not_active Application Discontinuation
-
2003
- 2003-03-14 HK HK03101859.5A patent/HK1049655B/zh not_active IP Right Cessation
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