YU111292A - Naprava za regulisano ispuštanje disperzije leka - Google Patents

Naprava za regulisano ispuštanje disperzije leka

Info

Publication number
YU111292A
YU111292A YU111292A YU111292A YU111292A YU 111292 A YU111292 A YU 111292A YU 111292 A YU111292 A YU 111292A YU 111292 A YU111292 A YU 111292A YU 111292 A YU111292 A YU 111292A
Authority
YU
Yugoslavia
Prior art keywords
hydration
gelatinous
polymer
core
dispersion
Prior art date
Application number
YU111292A
Other languages
English (en)
Other versions
YU48762B (sh
Inventor
G.S. Pork
J.D. Pipkin
Original Assignee
Merck & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. filed Critical Merck & Co.
Publication of YU111292A publication Critical patent/YU111292A/sh
Publication of YU48762B publication Critical patent/YU48762B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)

Abstract

NAPRAVA ZA REGULISANO ISPUŠTANJE DISPERZIJE LEKA, pronalazak se odnosi na napravu (10) za regulisano ispuštanje jednog delotvornog agensa (12) kao želatinozne disperzije, koja se sastoji od (i) jednog jezgra (11) koje sadrži delotvorni agens (12), polimer (13) koji nakon hidratacije obrazuje želatinozne mikros-kopske čestice i, ako se želi, neki agens (14) za modulisanje hidratacije polimera, i (ii) jednu nepropustljivu, nerastvorljivu oblogu (16) koja prianja na, i okružuje, jezgro (11) i sadrži otvore (17) koji obezbedjuju jedno područje za hidrataciju i ispuštanje disperzije koja sadrži želatinozne mikroskopske čestice.
YU111292A 1991-12-27 1992-12-25 Naprava za regulisano ispuštanje disperzije hemijskog jedinjenja YU48762B (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81530491A 1991-12-27 1991-12-27
US90218892A 1992-07-29 1992-07-29

Publications (2)

Publication Number Publication Date
YU111292A true YU111292A (sh) 1995-12-04
YU48762B YU48762B (sh) 1999-11-22

Family

ID=27123932

Family Applications (1)

Application Number Title Priority Date Filing Date
YU111292A YU48762B (sh) 1991-12-27 1992-12-25 Naprava za regulisano ispuštanje disperzije hemijskog jedinjenja

Country Status (26)

Country Link
EP (1) EP0549331B1 (sh)
JP (1) JPH089534B2 (sh)
KR (1) KR100281609B1 (sh)
CN (1) CN1074368A (sh)
AT (1) ATE157001T1 (sh)
AU (1) AU660057B2 (sh)
BG (1) BG61751B1 (sh)
CA (1) CA2085871C (sh)
CZ (1) CZ284045B6 (sh)
DE (1) DE69221711T2 (sh)
DK (1) DK0549331T3 (sh)
ES (1) ES2106838T3 (sh)
FI (1) FI109451B (sh)
GR (1) GR3024885T3 (sh)
HU (1) HU219594B (sh)
IL (1) IL104189A (sh)
LV (1) LV12082B (sh)
MX (1) MX9207541A (sh)
NO (1) NO310672B1 (sh)
NZ (1) NZ245514A (sh)
PL (1) PL171110B1 (sh)
RO (1) RO112810B1 (sh)
RU (1) RU2127586C1 (sh)
SK (1) SK279964B6 (sh)
WO (1) WO1993012765A1 (sh)
YU (1) YU48762B (sh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582838A (en) * 1994-12-22 1996-12-10 Merck & Co., Inc. Controlled release drug suspension delivery device
US5654005A (en) * 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
DE59803511D1 (de) * 1997-01-14 2002-05-02 Lohmann Therapie Syst Lts Expandierbares gastroretentives therapie-system mit kontrollierter wirkstofffreisetzung im gastrointestinaltrakt
TWI243687B (en) * 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US6506397B1 (en) * 1999-02-19 2003-01-14 Curt Thies Pest controlling
AU3957400A (en) 1999-04-16 2000-11-02 Novo Nordisk A/S Dry, mouldable drug formulation
US6861071B2 (en) * 2000-08-08 2005-03-01 Daiichi Pharmaceutical Co., Ltd. Highly absorptive solid preparation
CA2434169C (en) 2001-01-12 2011-03-15 Sun Pharmaceutical Industries Limited Spaced drug delivery system
AU2002353659A1 (en) * 2001-12-18 2003-07-15 Synthon B.V. Simvastatin dosage forms
US8454997B2 (en) 2001-12-18 2013-06-04 Novo Nordisk A/S Solid dose micro implant
WO2003051328A1 (en) * 2001-12-18 2003-06-26 Novo Nordisk A/S Solid dose micro implant
AR040588A1 (es) * 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
EP2255795A1 (en) * 2002-09-28 2010-12-01 McNeil-PPC, Inc. Immediate release dosage form comprising shell having openings therein
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US7922702B2 (en) 2004-07-02 2011-04-12 Qlt Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such a delivery device
US8795711B2 (en) 2006-03-31 2014-08-05 Mati Therapeutics Inc. Drug delivery methods, structures, and compositions for nasolacrimal system
EP2205193A2 (en) 2007-09-07 2010-07-14 QLT Plug Delivery, Inc. Lacrimal implant detection
CN103889401B (zh) 2011-08-29 2017-10-13 Qlt公司 持续释放递送活性剂以治疗青光眼和高眼压
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
JP2020066606A (ja) * 2018-10-25 2020-04-30 株式会社ダイセル １型ヘルパーｔ細胞増加剤、食品、及び医薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4915954A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering a drug at two different rates
US4814181A (en) * 1987-09-03 1989-03-21 Alza Corporation Dosage form comprising fast agent delivery followed by slow agent delivery
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin

Also Published As

Publication number Publication date
PL171110B1 (pl) 1997-03-28
DE69221711T2 (de) 1998-03-12
AU660057B2 (en) 1995-06-08
DE69221711D1 (de) 1997-09-25
CA2085871A1 (en) 1993-06-28
SK76994A3 (en) 1995-05-10
BG61751B1 (bg) 1998-05-29
BG98805A (bg) 1995-03-31
CN1074368A (zh) 1993-07-21
CZ157094A3 (en) 1994-12-15
AU3034892A (en) 1993-08-12
EP0549331A1 (en) 1993-06-30
WO1993012765A1 (en) 1993-07-08
HU9401913D0 (en) 1994-09-28
RU94031474A (ru) 1997-04-20
YU48762B (sh) 1999-11-22
LV12082A (lv) 1998-07-20
IL104189A (en) 1996-10-31
MX9207541A (es) 1994-06-30
KR100281609B1 (ko) 2001-02-15
RU2127586C1 (ru) 1999-03-20
ATE157001T1 (de) 1997-09-15
EP0549331B1 (en) 1997-08-20
ES2106838T3 (es) 1997-11-16
JPH05255071A (ja) 1993-10-05
CZ284045B6 (cs) 1998-07-15
LV12082B (en) 1998-09-20
JPH089534B2 (ja) 1996-01-31
RO112810B1 (ro) 1998-01-30
NO942430L (no) 1994-06-27
HUT70437A (en) 1995-10-30
SK279964B6 (sk) 1999-06-11
FI943011A (fi) 1994-06-22
IL104189A0 (en) 1993-05-13
NO310672B1 (no) 2001-08-13
DK0549331T3 (da) 1997-09-15
GR3024885T3 (en) 1998-01-30
KR940703653A (ko) 1994-12-12
NO942430D0 (no) 1994-06-27
FI943011A0 (fi) 1994-06-22
HU219594B (hu) 2001-05-28
NZ245514A (en) 1994-12-22
CA2085871C (en) 2002-05-07
FI109451B (fi) 2002-08-15

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