YU101692A - SUBSTITUTED BENZIMIDAZOLES AND THE PROCEDURE FOR THEIR MANAGEMENT - Google Patents

SUBSTITUTED BENZIMIDAZOLES AND THE PROCEDURE FOR THEIR MANAGEMENT

Info

Publication number
YU101692A
YU101692A YU101692A YU101692A YU101692A YU 101692 A YU101692 A YU 101692A YU 101692 A YU101692 A YU 101692A YU 101692 A YU101692 A YU 101692A YU 101692 A YU101692 A YU 101692A
Authority
YU
Yugoslavia
Prior art keywords
compounds
management
procedure
substituted benzimidazoles
methyl
Prior art date
Application number
YU101692A
Other languages
Serbo-Croatian (sh)
Inventor
K.B.C. Holstein
Elisabeth Sunden Gunnel
Original Assignee
Aktiebol Aget Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebol Aget Astra filed Critical Aktiebol Aget Astra
Publication of YU101692A publication Critical patent/YU101692A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Abstract

SUPSTITUISANI BENZIMIDAZOLI I POSTUPAK ZA NJIHOVO PRAVLJENJE, nova jedinjenja formule I: u kojoj: R1 i R2, koji su različiti, je svaki metil, -C(O)-CH3 ili -C(O)-OCH3, i gde je jedan od R1 ili R2 uvek metil; i M je fiziološki prihvatljiv suprotni katjon, kao i postupci za pravljenje pomenutih jedinjenja, farmaceutski preparati koji sadrže pomenuta jedinjenja kao aktivan sastojak, i primena jedinjenja u medicini.SUBSTITUTED BENZIMIDAZOLES AND PROCESS FOR THEIR PREPARATION, novel compounds of formula I: wherein: R 1 and R 2, which are different, are each methyl, -C (O) -CH 3 or -C (O) -OCH 3, and wherein one of R 1 or R2 is always methyl; and M is a physiologically acceptable counter cation, as well as methods for making said compounds, pharmaceutical compositions containing said compounds as active ingredient, and the use of the compounds in medicine.

YU101692A 1991-12-19 1992-11-25 SUBSTITUTED BENZIMIDAZOLES AND THE PROCEDURE FOR THEIR MANAGEMENT YU101692A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9103776A SE9103776D0 (en) 1991-12-19 1991-12-19 NEW COMPOUNDS

Publications (1)

Publication Number Publication Date
YU101692A true YU101692A (en) 1995-10-03

Family

ID=20384667

Family Applications (1)

Application Number Title Priority Date Filing Date
YU101692A YU101692A (en) 1991-12-19 1992-11-25 SUBSTITUTED BENZIMIDAZOLES AND THE PROCEDURE FOR THEIR MANAGEMENT

Country Status (25)

Country Link
EP (1) EP0628049A1 (en)
JP (1) JPH07502503A (en)
KR (1) KR940703840A (en)
CN (1) CN1031827C (en)
AP (1) AP397A (en)
AU (1) AU665043B2 (en)
CA (1) CA2124689A1 (en)
CZ (1) CZ146794A3 (en)
FI (1) FI942912A (en)
HR (1) HRP921400A2 (en)
HU (1) HUT68270A (en)
IL (1) IL104025A0 (en)
IS (2) IS4079A (en)
MA (1) MA22746A1 (en)
MX (1) MX9207269A (en)
NO (1) NO942230L (en)
NZ (1) NZ246220A (en)
SE (1) SE9103776D0 (en)
SI (1) SI9200402A (en)
SK (1) SK73594A3 (en)
TN (1) TNSN92115A1 (en)
TW (1) TW224100B (en)
WO (1) WO1993012124A1 (en)
YU (1) YU101692A (en)
ZA (1) ZA928836B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19645974C1 (en) * 1996-11-07 1998-08-13 Andreas Johannes Kesel (Z) -5 - [[3-Hydroxy-2-methyl-5 - [(phosphonooxy) methyl] -4-pyridinyl] methylene] -2-thioxo-4-thiazolidinone, process for its preparation and use
WO1999033846A2 (en) * 1997-12-31 1999-07-08 The University Of Kansas Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof
ATE467637T1 (en) 2005-07-28 2010-05-15 Intervet Int Bv NEW BENZIMIDAZOLE(THIO)CARBAMATES WITH ANTIPARASITIC EFFECT AND THEIR SYNTHESIS
TWI385169B (en) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd Heterocyclic substituted pyridine derivatives and antifungal agent containing same
PL2037914T3 (en) 2006-06-14 2014-04-30 Intervet Int Bv A suspension comprising benzimidazole carbamate and a polysorbate
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
US8513287B2 (en) * 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
MX365051B (en) 2014-11-26 2019-05-09 Univ Mexico Nac Autonoma Novel hydrosoluble compounds derived from benzimidazole used in treating fasciolosis.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
SE8801907D0 (en) * 1988-05-20 1988-05-20 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
SE9002206D0 (en) * 1990-06-20 1990-06-20 Haessle Ab NEW COMPOUNDS
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use

Also Published As

Publication number Publication date
MA22746A1 (en) 1993-07-01
AU3175293A (en) 1993-07-19
TW224100B (en) 1994-05-21
CN1073446A (en) 1993-06-23
FI942912A0 (en) 1994-06-17
NO942230D0 (en) 1994-06-14
AP397A (en) 1995-08-14
ZA928836B (en) 1993-07-05
HUT68270A (en) 1995-06-28
HU9401840D0 (en) 1994-09-28
AU665043B2 (en) 1995-12-14
MX9207269A (en) 1993-06-01
IS4079A (en) 1993-06-20
TNSN92115A1 (en) 1993-06-08
CA2124689A1 (en) 1993-06-24
KR940703840A (en) 1994-12-12
SE9103776D0 (en) 1991-12-19
NZ246220A (en) 1996-02-27
HRP921400A2 (en) 1994-08-31
SI9200402A (en) 1993-06-30
EP0628049A1 (en) 1994-12-14
CN1031827C (en) 1996-05-22
SK73594A3 (en) 1995-02-08
FI942912A (en) 1994-06-17
AP9200463A0 (en) 1993-01-31
JPH07502503A (en) 1995-03-16
NO942230L (en) 1994-06-14
CZ146794A3 (en) 1996-02-14
IL104025A0 (en) 1993-05-13
IS3960A (en) 1993-06-20
WO1993012124A1 (en) 1993-06-24

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