YU55495A - USE OF BENZOTHOPHENE TO OBTAIN MEDICINE - Google Patents

USE OF BENZOTHOPHENE TO OBTAIN MEDICINE

Info

Publication number
YU55495A
YU55495A YU55495A YU55495A YU55495A YU 55495 A YU55495 A YU 55495A YU 55495 A YU55495 A YU 55495A YU 55495 A YU55495 A YU 55495A YU 55495 A YU55495 A YU 55495A
Authority
YU
Yugoslavia
Prior art keywords
benzothiophene
benzothophene
obtain medicine
hexamethyleneamino
piperidino
Prior art date
Application number
YU55495A
Other languages
Serbo-Croatian (sh)
Inventor
Sales
Original Assignee
Eli Lilly And Company Indianapolis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Indianapolis filed Critical Eli Lilly And Company Indianapolis
Publication of YU55495A publication Critical patent/YU55495A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

Opisana je upotreba benzotiofena za dobijanje leka gde je benzotiofen jedinjenje formule u kojoj su R1 i R3 nezavisno vodonik, -CH3, -C-(-C1-C6alkil), ili -C-Ar, gde je Ar opciono supstituisan fenil; R2 je odabrano iz grupe koja se sastoji od pirolidina, heksametilenamino i piperidino; ili njegova farmaceutski prihvatljiva so ili solvat. Benzotiofen se meša sa uobičajenim ekcipijentima, razblaživačima ili nosačima.The use of a benzothiophene for the preparation of a medicament is described wherein the benzothiophene is a compound of the formula wherein R 1 and R 3 are independently hydrogen, -CH 3, -C - (- C 1 -C 6 alkyl), or -C-Ar, wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneamino and piperidino; or a pharmaceutically acceptable salt or solvate thereof. Benzothiophene is mixed with common excipients, diluents or carriers.

YU55495A 1994-08-22 1995-08-21 USE OF BENZOTHOPHENE TO OBTAIN MEDICINE YU55495A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29423794A 1994-08-22 1994-08-22

Publications (1)

Publication Number Publication Date
YU55495A true YU55495A (en) 1998-07-10

Family

ID=23132491

Family Applications (1)

Application Number Title Priority Date Filing Date
YU55495A YU55495A (en) 1994-08-22 1995-08-21 USE OF BENZOTHOPHENE TO OBTAIN MEDICINE

Country Status (14)

Country Link
EP (1) EP0769946A4 (en)
JP (1) JPH10504573A (en)
KR (1) KR970705386A (en)
AU (1) AU692598B2 (en)
CA (1) CA2198108A1 (en)
CZ (1) CZ52197A3 (en)
FI (1) FI970713A (en)
HU (1) HUT76891A (en)
IL (1) IL115017A0 (en)
MX (1) MX9701331A (en)
NO (1) NO970784D0 (en)
WO (1) WO1996005829A1 (en)
YU (1) YU55495A (en)
ZA (1) ZA956987B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss

Also Published As

Publication number Publication date
EP0769946A4 (en) 1997-11-05
FI970713A0 (en) 1997-02-20
HUT76891A (en) 1997-12-29
CZ52197A3 (en) 1997-08-13
NO970784L (en) 1997-02-20
AU3408895A (en) 1996-03-14
ZA956987B (en) 1997-02-21
JPH10504573A (en) 1998-05-06
AU692598B2 (en) 1998-06-11
CA2198108A1 (en) 1996-02-29
MX9701331A (en) 1997-05-31
EP0769946A1 (en) 1997-05-02
FI970713A (en) 1997-02-20
WO1996005829A1 (en) 1996-02-29
KR970705386A (en) 1997-10-09
NO970784D0 (en) 1997-02-20
IL115017A0 (en) 1995-12-08

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