WO2024108661A1 - 腔道支架制备方法 - Google Patents
腔道支架制备方法 Download PDFInfo
- Publication number
- WO2024108661A1 WO2024108661A1 PCT/CN2022/137693 CN2022137693W WO2024108661A1 WO 2024108661 A1 WO2024108661 A1 WO 2024108661A1 CN 2022137693 W CN2022137693 W CN 2022137693W WO 2024108661 A1 WO2024108661 A1 WO 2024108661A1
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- WIPO (PCT)
- Prior art keywords
- spiral tube
- spiral
- preparing
- spiral groove
- tube
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 45
- 239000000126 substance Substances 0.000 claims abstract description 23
- 238000004804 winding Methods 0.000 claims abstract description 20
- 239000000463 material Substances 0.000 claims description 5
- 230000003044 adaptive effect Effects 0.000 abstract description 7
- 239000000243 solution Substances 0.000 description 9
- 239000011295 pitch Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000000084 colloidal system Substances 0.000 description 3
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 210000000013 bile duct Anatomy 0.000 description 2
- 210000003238 esophagus Anatomy 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 210000003437 trachea Anatomy 0.000 description 2
- 210000003708 urethra Anatomy 0.000 description 2
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 210000004081 cilia Anatomy 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 230000005389 magnetism Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
Definitions
- the present invention relates to the technical field of medical appliances, and in particular to a method for preparing a cavity stent.
- stents are needed in natural cavities of the human body, such as the trachea, esophagus, bile duct or urethra, due to pathological changes or invasive treatment measures.
- Some cavitary stents use barrel-shaped stents, but the size of barrel-shaped stents is difficult to adjust, lacks adaptability to the internal structure of the cavity, and is prone to cause poor gas and liquid circulation during use due to its thick wall.
- the barrel-shaped stent is also prone to hinder the cilia movement and mucus exchange of some cavities within the stent coverage area; some cavitary stents use memory alloys to form an integral mesh stent, but memory alloys may form a relatively large extrusion force, which is easy to induce the growth of tracheal epithelial tissue and form granulation tissue, and also increases the difficulty of removing the cavitary stent and the intraoperative risk.
- Some cavity stents use a braided mesh stent, which maintains the structure fixed by multiple abutments between the braided wires.
- this type of stent is difficult to deform and it is difficult to perform structural adaptive deformation.
- the main purpose of the present invention is to provide a method for preparing a cavity stent, so as to manufacture a cavity stent with structural self-adaptation characteristics.
- the method for preparing a cavity stent proposed in the present invention includes the following steps: preparing a columnar mold so that a first spiral groove is provided on the side wall surface of the columnar mold; winding along the first spiral groove to form a first spiral tube; fixing the first spiral tube so that the first spiral tube maintains a preset shape; and injecting a substance to be solidified into the first spiral tube.
- the step of preparing the columnar mold also includes: providing a second spiral groove on the side wall surface of the columnar mold, and the rotation direction of the second spiral groove is opposite to that of the first spiral groove; the method for preparing the cavity stent also includes the following steps: winding along the second spiral groove to form a second spiral tube, so that the second spiral tube forms at least one abutment point with the first spiral tube.
- the step of fixing the first spiral tube so that the first spiral tube maintains a preset shape further includes: fixing the abutment point to form a polygonal structure, and the number of sides of the polygonal structure is greater than or equal to four.
- the step of preparing the columnar mold further includes: providing at least two spiral groove groups on the side wall surface of the columnar mold, the spiral groove groups being arranged at intervals along the circumferential direction, and the spiral groove groups including the first spiral groove and/or the second spiral groove.
- the step of fixing the abutment point to form the polygonal structure includes: using a circumferential binding line to wind and fix the abutment point in parallel to the circumferential direction of the first spiral tube; and/or using an axial binding line to wind and fix the abutment point in parallel to the axial direction of the first spiral tube;
- the method for preparing the cavity stent further includes the following steps: inserting one end of the plug into the port of the first spiral tube, inserting the other end of the plug into the port of the second spiral tube, and the port of the second spiral tube is arranged opposite to the port of the first spiral tube.
- the method for preparing the cavity stent also includes the following steps: using a tube to wind along the first spiral groove to form the first spiral tube until it is wound to the intersection of the first spiral groove and the second spiral groove; then winding the tube along the second spiral groove to form the second spiral tube, so that the first spiral tube and the second spiral tube are integrally formed at the other end in the axial direction.
- the method for preparing the cavity stent further includes the following steps: making the diameter of the first spiral tube greater than or equal to the diameter of the first spiral groove; or making the diameter of the first spiral tube smaller than the diameter of the first spiral groove.
- the step of injecting the substance to be cured into the first spiral tube is performed before the step of winding along the first spiral groove to form the first spiral tube; or, after the step of fixing the first spiral tube so that the first spiral tube maintains a preset shape, the step of injecting the substance to be cured into the first spiral tube is performed.
- the method for preparing the cavity stent further includes the following steps: preliminarily fixing the first spiral tube formed by winding; separating the first spiral tube from the columnar mold; and adjusting the first spiral tube to a preset diameter value corresponding to the preset shape.
- the technical solution of the present invention is to set the cavity stent preparation method to include the following steps: prepare a columnar mold, so that the side wall surface of the columnar mold has a first spiral groove; wind along the first spiral groove to form a first spiral tube; fix the first spiral tube so that the first spiral tube maintains a preset shape; inject the substance to be cured into the first spiral tube; at this time, the first spiral tube can be formed by winding the first spiral groove on the side wall surface of the columnar mold, and then fixed to maintain the preset shape; inject the substance to be cured into the first spiral tube, so that the prepared cavity stent can adjust the shape and size and maintain elasticity before the substance to be cured is cured, so as to facilitate installation in cavities of different structures; and the prepared cavity stent can provide stable support after the substance to be cured is cured and perform structural adaptive deformation, that is, the manufactured cavity stent can have structural adaptive characteristics.
- FIG. 1 is a diagram showing the steps of an embodiment of a method for preparing a cavity stent according to the present invention.
- FIG. 2 is a schematic diagram of an embodiment of a columnar mold in the present invention.
- FIG. 3 is a schematic diagram of a cavity stent prepared by an embodiment of a method for preparing a cavity stent of the present invention.
- FIG. 4 is a schematic diagram of a cavity stent prepared by another embodiment of the method for preparing a cavity stent of the present invention.
- FIG. 5 is a cross-sectional view of a first spiral tube in an embodiment of a method for preparing a lumen stent of the present invention.
- the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.
- directional indications such as up, down, left, right, front, back, etc.
- the present invention provides a method for preparing a cavity stent, which is convenient for manufacturing a cavity stent with structural adaptability.
- the cavity stent can be suitable for natural cavities of the human body such as the trachea, esophagus, bile duct or urethra.
- the method for preparing the cavity stent comprises the following steps:
- Step S100 preparing a columnar mold 100, so that a first spiral groove 101 is provided on the side wall surface of the columnar mold 100;
- the shape of the columnar mold 100 can be referred to FIG. 2, and the columnar mold 100 and the first spiral groove 101 can be made by machining, injection molding, casting, etc.;
- Step S200 winding along the first spiral groove 101 to form a first spiral tube 110;
- Step S300 fixing the first spiral tube 110 so that the first spiral tube 110 maintains a preset shape
- the first spiral tube 110 may be fixed by a fixing member such as a rope, a buckle, a pre-tightening member, an external mold, etc., which is not limited in this embodiment;
- Step S400 injecting the material to be cured 111 into the first spiral tube 110, the material to be cured 111 can be set as a fluid to be cured or a colloid to be cured; wherein, the colloid to be cured can be made of one of near-infrared light glue and ultraviolet light glue, and the colloid to be cured can be cured by light induction.
- the material to be cured 111 can be a material that can be cured by physical means such as magnetism, heat, etc., and this embodiment does not limit this.
- the method for preparing the cavity stent can form a first spiral tube 110 by winding the first spiral groove 101 on the side wall surface of the columnar mold 100, and then fix it to maintain a preset shape; injecting the to-be-cured substance 111 into the first spiral tube 110 can enable the prepared cavity stent to adjust its shape and size and maintain elasticity before the to-be-cured substance is cured, so as to facilitate installation in cavities of different structures; and can also enable the prepared cavity stent to provide stable support after the to-be-cured substance is cured and perform structural adaptive deformation, that is, the manufactured cavity stent can have structural adaptive characteristics.
- the step of preparing the columnar mold 100 also includes: providing a second spiral groove 102 on the side wall surface of the columnar mold 100, and the rotation direction of the second spiral groove 102 is opposite to the rotation direction of the first spiral groove 101.
- the second spiral groove 102 and the first spiral groove 101 form at least one intersection (corresponding to the abutment point between the second spiral tube 120 and the first spiral tube 110 described below);
- the method for preparing the cavity stent also includes the following steps: winding along the second spiral groove 102 to form the second spiral tube 120, so that the second spiral tube 120 and the first spiral tube 110 form at least one abutment point.
- the step of fixing the first spiral tube 110 so that the first spiral tube 110 maintains a preset shape further includes: fixing the abutment points to form a polygonal structure.
- the method for preparing the luminal stent can more efficiently prepare a luminal stent with more supporting positions through the columnar mold 100 and the fixed abutment points.
- the step of fixing the first spiral tube 110 so that the first spiral tube 110 maintains a preset shape includes:
- the first spiral tube 110 is formed into a polygonal structure to maintain a preset shape, and the number of sides of the polygonal structure is greater than or equal to four, which can be specifically achieved by the above-mentioned fixing member or by a fixture.
- the step of preparing the columnar mold 100 further includes: providing at least two spiral groove groups on the side wall surface of the columnar mold 100, the spiral groove groups are arranged at intervals along the circumferential direction, and the spiral groove groups include a first spiral groove 101 and/or a second spiral groove 102.
- the method for preparing a luminal stent can further improve the preparation of a luminal stent with more support points.
- the step of fixing the abutment point to form a polygonal structure includes: using a circumferential binding line 210 to wind and fix the abutment point in parallel to the circumferential direction of the first spiral tube 110; and/or using an axial binding line 220 to wind and fix the abutment point in parallel to the axial direction of the first spiral tube 110.
- the circumferential binding line 210 and the axial binding line 220 can more conveniently pass through the small space between the first spiral tube 110, the second spiral tube 120 and the columnar mold 100, which can reduce the impact caused by the small space between the columnar mold 100 and the first spiral tube 110, the second spiral tube 120, so that the preparation method of the luminal stent maintains a high preparation efficiency.
- the method for preparing the luminal stent further includes the following steps: inserting one end of the plug 300 into the port of the first spiral tube 110, inserting the other end of the plug 300 into the port of the second spiral tube 120, and the port of the second spiral tube 120 is arranged opposite to the port of the first spiral tube 110.
- the method for preparing the luminal stent can effectively seal the substance to be solidified 111 to prevent leakage of the substance to be solidified 111.
- the method for preparing the cavity stent also includes the following steps: using a pipe to wind along the first spiral groove 101 to form a first spiral tube 110, until it is wound to the intersection of the first spiral groove 101 and the second spiral groove 102; then winding the pipe along the second spiral groove 102 to form a second spiral tube 120, so that the first spiral tube 110 and the second spiral tube 120 are integrally formed at the other end in the axial direction; specifically, a specific length of the first spiral groove 101 and the second spiral groove 102 can be selected, and the specific length can be set to an integer multiple of 0.25 pitches, specifically including an integer number of pitches and 0.25 pitches, or an integer number of pitches and 0.75 pitches, so that the method for preparing the cavity stent can use the same pipe to wind the integrally formed first spiral tube 110 and second spiral tube 120, thereby further improving manufacturing efficiency.
- the method for preparing the luminal stent further includes the following steps: making the diameter of the first spiral tube 110 greater than or equal to the diameter of the first spiral groove 101; or making the diameter of the first spiral tube 110 smaller than the diameter of the first spiral groove 101.
- the method for preparing the luminal stent further includes the following steps: preliminarily fixing the first spiral tube 110 formed by winding; making the first spiral tube 110 separate from the columnar mold 100; adjusting the first spiral tube 110 to a preset diameter value corresponding to the preset shape, even if the diameter of the first spiral tube 110 is greater than or equal to the diameter of the first spiral groove 101 or making the diameter of the first spiral tube 110 smaller than the diameter of the first spiral groove 101.
- the diameter of the luminal stent can be roughly determined by the columnar mold 100 first, and then the diameter value can be fine-tuned after the luminal stent is demoulded, so that the diameter adjustment of the luminal stent is more stable and controllable, and the number of specifications of the columnar mold 100 can also be reduced.
- the above-mentioned preliminary fixing and fixing of the first spiral tube 110 so that the first spiral tube 110 maintains a preset shape can be adjusted by adjusting the winding strength of the circumferential binding wire 210 and the axial binding wire 220 .
- the step of injecting the substance to be cured 111 into the first spiral tube 110 is performed before the step of winding along the first spiral groove 101 to form the first spiral tube 110; at this time, the filling degree of the substance to be cured 111 is increased, which is not only conducive to the binding of the binding parts, but also conducive to the step of injecting the substance to be cured 111 and preparing the columnar mold 100 to improve the manufacturing efficiency.
- the step of injecting the substance to be cured 111 into the first spiral tube 110 is performed to prevent the injection power of the substance to be cured 111 from causing the first spiral tube 110 to deform.
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Abstract
一种腔道支架制备方法，包括以下步骤：制备柱状模具（100），使柱状模具（100）的侧壁面上具有第一螺旋凹槽（101）；沿第一螺旋凹槽（101）缠绕形成第一螺旋管（110）；固定第一螺旋管（110）以使第一螺旋管（110）保持预设形态；在第一螺旋管（110）内注入待固化物质（111）。腔道支架制备方法能够通过柱状模具（100）上的第一螺旋凹槽（101）缠绕形成第一螺旋管（110），并在后续固定而保持预设形态；在第一螺旋管（110）内注入待固化物质，既能够使制备得到的腔道支架在待固化物质固化前调节形态大小并保持弹性，便于安装到不同结构的腔道中；又能够使制备得到的腔道支架在待固化物质固化后提供稳定的支撑而进行结构适应性变形，即制造出的腔道支架对于复杂病变腔道具有结构自适应特性。
Description
本发明涉及医疗用具技术领域，特别涉及一种腔道支架制备方法。
气管、食道、胆道或尿道等人体自然腔道有时会因发生病变，或者因侵入性治疗措施，而需要在腔道中使用支架。部分腔道支架采用桶状支架，但桶状支架大小调整困难，缺乏对于腔道内部结构的适应性，且易因其壁厚较大而在使用时导致气、液流通不顺畅，桶状支架在支架覆盖区域内也容易阻碍部分腔道的纤毛运动及粘液交换；部分腔道支架采用记忆合金来形成整体式网状支架，但记忆合金可能形成偏大的挤压力，易诱发气管上皮组织生长而形成肉芽，也增加了腔道支架移除的难度与术中风险。
部分腔道支架采用编织式的网状支架，通过编织线相互之间的多处抵接来保持结构的固定，但该类支架变形较难，难以进行结构适应性变形。
本发明的主要目的是提出一种腔道支架制备方法，以便于制造出具有结构自适应特性的腔道支架。
为实现上述目的，本发明提出的腔道支架制备方法包括以下步骤：制备柱状模具，使所述柱状模具的侧壁面上具有第一螺旋凹槽；沿所述第一螺旋凹槽缠绕形成第一螺旋管；固定所述第一螺旋管以使所述第一螺旋管保持预设形态；在所述第一螺旋管内注入待固化物质。
可选地，所述制备柱状模具的步骤还包括：使所述柱状模具侧壁面上具有第二螺旋凹槽，所述第二螺旋凹槽的旋向与所述第一螺旋凹槽的旋向相反；所述腔道支架制备方法还包括以下步骤：沿所述第二螺旋凹槽缠绕形成第二螺旋管，使所述第二螺旋管与所述第一螺旋管形成至少一个抵接点。
可选地，所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤还包括：固定所述抵接点以形成多边形结构，所述多边形结构的边数大于等于四个。
可选地，所述制备柱状模具的步骤，还包括：使所述柱状模具侧壁面上具有至少两个螺旋凹槽组，所述螺旋凹槽组沿周向间隔设置，所述螺旋凹槽组包括所述第一螺旋凹槽和/或所述第二螺旋凹槽。
可选地，所述固定所述抵接点以形成所述多边形结构的步骤，包括：采用周向绑定线平行于所述第一螺旋管的周向方向缠绕并固定所述抵接点；和/或，采用轴向绑定线平行于所述第一螺旋管的轴向方向缠绕并固定所述抵接点；
可选地，所述腔道支架制备方法还包括以下步骤：将堵头的一端套设至所述第一螺旋管的端口内，将所述堵头的另一端套设至所述第二螺旋管的端口内，所述第二螺旋管的端口与所述第一螺旋管的端口相对设置。
可选地，所述腔道支架制备方法还包括以下步骤：采用管件沿所述第一螺旋凹槽缠绕形成所述第一螺旋管，直至缠绕至所述第一螺旋凹槽与所述第二螺旋凹槽的交点；再将所述管件沿所述第二螺旋凹槽缠绕形成所述第二螺旋管，以使所述第一螺旋管、所述第二螺旋管在轴向方向的另一端一体成型。
可选地，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤之前，所述腔道支架制备方法还包括以下步骤：使所述第一螺旋管的直径大于等于所述第一螺旋凹槽的直径；或，使所述第一螺旋管的直径小于所述第一螺旋凹槽的直径。
可选地，在沿所述第一螺旋凹槽缠绕形成第一螺旋管的步骤之前，执行所述在所述第一螺旋管内注入待固化物质的步骤；或，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤之后，执行所述在所述第一螺旋管内注入待固化物质的步骤。
可选地，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤前，所述述腔道支架制备方法还包括以下步骤：初步固定缠绕形成的所述的第一螺旋管；使所述第一螺旋管脱离所述柱状模具；将所述第一螺旋管调整至所述预设形态所对应的预设直径值。
本发明的技术方案通过将腔道支架制备方法设置为包括以下步骤：制备柱状模具，使柱状模具的侧壁面上具有第一螺旋凹槽；沿第一螺旋凹槽缠绕形成第一螺旋管；固定第一螺旋管以使第一螺旋管保持预设形态；在第一螺旋管内注入待固化物质；此时能够通过柱状模具的侧壁面上的第一螺旋凹槽缠绕形成第一螺旋管，并在后续固定而保持预设形态；在第一螺旋管内注入待固化物质，既能够使制备得到的腔道支架在待固化物质固化前调节形态大小并保持弹性，便于安装到不同结构的腔道中；又能够使制备得到的腔道支架在待固化物质固化后提供稳定的支撑而进行结构适应性变形，即制造出的腔道支架能够具有结构自适应特性。
果值
为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图示出的结构获得其他的附图。
图1为本发明腔道支架制备方法一实施例的步骤图。
图2为本发明中柱状模具一实施例的示意图。
图3为本发明腔道支架制备方法一实施例制备的腔道支架的示意图。
图4为本发明腔道支架制备方法另一实施例制备的腔道支架的示意图。
图5为本发明腔道支架制备方法一实施例中第一螺旋管的横截面视图。
附图标号说明：
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明的一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动的前提下所获得的所有其他实施例，都属于本发明保护的范围。
需要说明，若本发明实施例中有涉及方向性指示（诸如上、下、左、右、前、后……），则该方向性指示仅用于解释在某一特定姿态下各部件之间的相对位置关系、运动情况等，如果该特定姿态发生改变时，则该方向性指示也相应地随之改变。
另外，若本发明实施例中有涉及“第一”、“第二”等的描述，则该“第一”、“第二”等的描述仅用于描述目的，而不能理解为指示或暗示其相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”的特征可以明示或者隐含地包括至少一个该特征。另外，若全文中出现的“和/或”或者“及/或”，其含义包括三个并列的方案，以“A和/或B”为例，包括A方案、或B方案、或A和B同时满足的方案。另外，各个实施例之间的技术方案可以相互结合，但是必须是以本领域普通技术人员能够实现为基础，当技术方案的结合出现相互矛盾或无法实现时应当认为这种技术方案的结合不存在，也不在本发明要求的保护范围之内。
本发明提出一种腔道支架制备方法，便于制造出具有结构自适应性的腔道支架，该腔道支架可适用于气管、食道管、胆道或尿道等人体自然腔道。
参照图1至图3，在本发明一实施例中，该腔道支架制备方法包括以下步骤：
步骤S100，制备柱状模具100，使柱状模具100的侧壁面上具有第一螺旋凹槽101；该柱状模具100的形状可参照图2，柱状模具100及第一螺旋凹槽101可通过机械加工、注塑、铸造等方式制成；
步骤S200，沿第一螺旋凹槽101缠绕形成第一螺旋管110；
步骤S300，固定第一螺旋管110以使第一螺旋管110保持预设形态，如可采用绳、卡扣、预紧件、外模具等固定件进行固定，本实施例对此不加以限制；
步骤S400，在第一螺旋管110内注入待固化物质111，待固化物质111可设置为待固化流体或待固化胶体；其中，待固化胶体可采用近红外光胶、紫外光胶其中一种来制成，此时可通过光诱发对待固化胶体进行固化。此外，待固化物质111可采用通过诸如磁、热等物理方式进行固化的物质，本实施例对此不加以限制。
此时腔道支架制备方法能够通过柱状模具100的侧壁面上的第一螺旋凹槽101缠绕形成第一螺旋管110，并在后续固定而保持预设形态；在第一螺旋管110内注入待固化物质111，既能够使制备得到的腔道支架在待固化物质固化前调节形态大小并保持弹性，便于安装到不同结构的腔道中；又能够使制备得到的腔道支架在待固化物质固化后提供稳定的支撑而进行结构适应性变形，即制造出的腔道支架能够具有结构自适应特性。
进一步作为可选的实施方式，参照图1，制备柱状模具100的步骤还包括：使柱状模具100侧壁面上具有第二螺旋凹槽102，第二螺旋凹槽102的旋向与第一螺旋凹槽101的旋向相反，则此时第二螺旋凹槽102与第一螺旋凹槽101形成至少一个交点（与下述第二螺旋管120与第一螺旋管110的抵接点相对应）；腔道支架制备方法还包括以下步骤：沿第二螺旋凹槽102缠绕形成第二螺旋管120，使第二螺旋管120与第一螺旋管110形成至少一个抵接点。
进一步作为可选的实施方式，固定第一螺旋管110以使第一螺旋管110保持预设形态的步骤还包括：固定抵接点以形成多边形结构。此时，腔道支架制备方法能够通过柱状模具100以及固定抵接点的形式，较为高效地制备出具有更多支撑位置的腔道支架。
进一步作为可选的实施方式，固定第一螺旋管110以使第一螺旋管110保持预设形态的步骤，包括：
使第一螺旋管110形成多边形结构以保持预设形态，多边形结构的边数大于等于四个，具体可通过上述固定件或通过工装夹具。
进一步作为可选的实施方式，制备柱状模具100的步骤，还包括：使柱状模具100侧壁面上具有至少两个螺旋凹槽组，螺旋凹槽组沿周向间隔设置，螺旋凹槽组包括第一螺旋凹槽101和/或第二螺旋凹槽102。在该方案中，腔道支架制备方法能够进一步提高制备出具有更多支撑点的腔道支架。
进一步作为可选的实施方式，固定抵接点以形成多边形结构的步骤，包括：采用周向绑定线210平行于第一螺旋管110的周向方向缠绕并固定抵接点；和/或，采用轴向绑定线220平行于第一螺旋管110的轴向方向缠绕并固定抵接点。当第一螺旋管110、第二螺旋管120缠绕柱状模具100上时，第一螺旋管110、第二螺旋管120与柱状模具100之间的空间狭小，采用周向绑定线210、轴向绑定线220缠绕并固定的方式，周向绑定线210、轴向绑定线220较为便利地穿过第一螺旋管110、第二螺旋管120与柱状模具100之间的狭小空间，能够减小柱状模具100与第一螺旋管110、第二螺旋管120之间空间狭小所造成的影响，使腔道支架制备方法保持较高的制备效率。
进一步作为可选的实施方式，腔道支架制备方法还包括以下步骤：将堵头300的一端套设至第一螺旋管110的端口内，将堵头300的另一端套设至第二螺旋管120的端口内，第二螺旋管120的端口与第一螺旋管110的端口相对设置。此时腔道支架制备方法能够高效地将待固化物质111封堵住，避免待固化物质111的泄漏。
进一步作为可选的实施方式，腔道支架制备方法还包括以下步骤：采用管件沿第一螺旋凹槽101缠绕形成第一螺旋管110，直至缠绕至第一螺旋凹槽101与第二螺旋凹槽102的交点；再将管件沿第二螺旋凹槽102缠绕形成第二螺旋管120，以使第一螺旋管110、第二螺旋管120在轴向方向的另一端一体成型；具体而言，可选用第一螺旋凹槽101、第二螺旋凹槽102的特定长度，该特定长度可设置为0.25个螺距的整数倍，具体包括整数个螺距和0.25个螺距，或整数个螺距和0.75个螺距，使腔道支架制备方法通过同一管件绕制出一体成型的第一螺旋管110、第二螺旋管120，进一步提高制造效率。
进一步作为可选的实施方式，在固定第一螺旋管110以使第一螺旋管110保持预设形态的步骤之前，腔道支架制备方法还包括以下步骤：使第一螺旋管110的直径大于等于第一螺旋凹槽101的直径；或，使第一螺旋管110的直径小于第一螺旋凹槽101的直径。具体而言，在固定第一螺旋管110以使第一螺旋管110保持预设形态的步骤前，腔道支架制备方法还包括以下步骤：初步固定缠绕形成的第一螺旋管110；使第一螺旋管110脱离柱状模具100；将第一螺旋管110调整至预设形态所对应的预设直径值，即使第一螺旋管110的直径大于等于第一螺旋凹槽101的直径或使第一螺旋管110的直径小于第一螺旋凹槽101的直径。在该方案中，能够先通过柱状模具100大体确定腔道支架的直径，再在腔道支架脱模后微调直径值，使腔道支架的直径调节更稳定可控，也可以减少柱状模具100的规格数量。上述初步固定、固定第一螺旋管110以使第一螺旋管110保持预设形态，可通过调节周向绑定线210、轴向绑定线220的缠绕力度来调节。
进一步作为可选的实施方式，在沿第一螺旋凹槽101缠绕形成第一螺旋管110的步骤之前，执行在第一螺旋管110内注入待固化物质111的步骤；此时注入待固化物质111充盈程度提高，既有利于绑定件的绑定，也有利于将注入待固化物质111的步骤与制备柱状模具100而提高制造效率。作为另选的实施方式，在固定第一螺旋管110以使第一螺旋管110保持预设形态的步骤之后，执行在第一螺旋管110内注入待固化物质111的步骤，避免待固化物质111的注入动力导致第一螺旋管110发生变形。
以上所述仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是在本发明的技术构思下，利用本发明说明书及附图内容所作的等效结构变换，或直接/间接运用在其他相关的技术领域均包括在本发明的专利保护范围内。
Claims (10)
- 一种腔道支架制备方法，其特征在于，所述腔道支架制备方法包括以下步骤：制备柱状模具，使所述柱状模具的侧壁面上具有第一螺旋凹槽；沿所述第一螺旋凹槽缠绕形成第一螺旋管；固定所述第一螺旋管以使所述第一螺旋管保持预设形态；在所述第一螺旋管内注入待固化物质。
- 如权利要求1所述的腔道支架制备方法，其特征在于，所述制备柱状模具的步骤还包括：使所述柱状模具侧壁面上具有第二螺旋凹槽，所述第二螺旋凹槽的旋向与所述第一螺旋凹槽的旋向相反；所述腔道支架制备方法还包括以下步骤：沿所述第二螺旋凹槽缠绕形成第二螺旋管，使所述第二螺旋管与所述第一螺旋管形成至少一个抵接点。
- 如权利要求2所述的腔道支架制备方法，所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤还包括：固定所述抵接点以形成多边形结构，所述多边形结构的边数大于等于四个。
- 如权利要求3所述的腔道支架制备方法，其特征在于，所述制备柱状模具的步骤，还包括：使所述柱状模具侧壁面上具有至少两个螺旋凹槽组，所述螺旋凹槽组沿周向间隔设置，所述螺旋凹槽组包括所述第一螺旋凹槽和/或所述第二螺旋凹槽。
- 如权利要求3或4所述的腔道支架制备方法，其特征在于，所述固定所述抵接点以形成所述多边形结构的步骤，包括：采用周向绑定线平行于所述第一螺旋管的周向方向缠绕并固定所述抵接点；和/或，采用轴向绑定线平行于所述第一螺旋管的轴向方向缠绕并固定所述抵接点；
- 如权利要求3或4所述的腔道支架制备方法，其特征在于，所述腔道支架制备方法还包括以下步骤：将堵头的一端套设至所述第一螺旋管的端口内，将所述堵头的另一端套设至所述第二螺旋管的端口内，所述第二螺旋管的端口与所述第一螺旋管的端口相对设置。
- 如权利要求6所述的腔道支架制备方法，其特征在于，所述腔道支架制备方法还包括以下步骤：采用管件沿所述第一螺旋凹槽缠绕形成所述第一螺旋管，直至缠绕至所述第一螺旋凹槽与所述第二螺旋凹槽的交点；再将所述管件沿所述第二螺旋凹槽缠绕形成所述第二螺旋管，以使所述第一螺旋管、所述第二螺旋管在轴向方向的另一端一体成型。
- 如权利要求1所述的腔道支架制备方法，其特征在于，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤之前，所述腔道支架制备方法还包括以下步骤：使所述第一螺旋管的直径大于等于所述第一螺旋凹槽的直径；或，使所述第一螺旋管的直径小于所述第一螺旋凹槽的直径。
- 如权利要求1所述的腔道支架制备方法，其特征在于，在沿所述第一螺旋凹槽缠绕形成第一螺旋管的步骤之前，执行所述在所述第一螺旋管内注入待固化物质的步骤；或，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤之后，执行所述在所述第一螺旋管内注入待固化物质的步骤。
- 如权利要求1所述的腔道支架制备方法，其特征在于，在所述固定所述第一螺旋管以使所述第一螺旋管保持预设形态的步骤前，所述述腔道支架制备方法还包括以下步骤：初步固定缠绕形成的所述的第一螺旋管；使所述第一螺旋管脱离所述柱状模具；将所述第一螺旋管调整至所述预设形态所对应的预设直径值。
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