WO2019004636A3 - 자동화된 핵산 분리 장치 - Google Patents

자동화된 핵산 분리 장치 Download PDF

Info

Publication number
WO2019004636A3
WO2019004636A3 PCT/KR2018/006745 KR2018006745W WO2019004636A3 WO 2019004636 A3 WO2019004636 A3 WO 2019004636A3 KR 2018006745 W KR2018006745 W KR 2018006745W WO 2019004636 A3 WO2019004636 A3 WO 2019004636A3
Authority
WO
WIPO (PCT)
Prior art keywords
vertical plate
plate
nucleic acid
separation apparatus
acid separation
Prior art date
Application number
PCT/KR2018/006745
Other languages
English (en)
French (fr)
Other versions
WO2019004636A2 (ko
Inventor
김근영
Original Assignee
(주)오상헬스케어
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)오상헬스케어 filed Critical (주)오상헬스케어
Publication of WO2019004636A2 publication Critical patent/WO2019004636A2/ko
Publication of WO2019004636A3 publication Critical patent/WO2019004636A3/ko

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Hydrology & Water Resources (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

개시되는 발명은 핵산 분리 장치에 관한 것으로서, 베이스 플레이트와, 상기 베이스 플레이트에 대해 일정 높이만큼 이격되게 배치되는 수평 플레이트와, 상기 수평 플레이트에 대해 수직으로 배치되는 수직 플레이트를 포함하는 고정 프레임;과, 상기 수직 플레이트 상에 상하 방향으로 이동 가능하도록 결합하는 피펫 블록;과, 상기 피펫 블록을 상하 방향으로 이송하도록 상기 수직 플레이트의 후면에 설치되는 제1구동부;와, 상기 수직 플레이트 상에 상기 피펫 블록의 상방에 배치되어 상하 방향으로 이동 가능하도록 결합하는 마그넷 블록; 및 상기 마그넷 블록을 상하 방향으로 이송하도록 상기 수직 플레이트의 후면에 설치되는 제2 구동부;를 포함한다.
PCT/KR2018/006745 2017-06-28 2018-06-15 자동화된 핵산 분리 장치 WO2019004636A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0081896 2017-06-28
KR1020170081896A KR20190001797A (ko) 2017-06-28 2017-06-28 자동화된 핵산 분리 장치

Publications (2)

Publication Number Publication Date
WO2019004636A2 WO2019004636A2 (ko) 2019-01-03
WO2019004636A3 true WO2019004636A3 (ko) 2019-05-23

Family

ID=64741684

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2018/006745 WO2019004636A2 (ko) 2017-06-28 2018-06-15 자동화된 핵산 분리 장치

Country Status (2)

Country Link
KR (1) KR20190001797A (ko)
WO (1) WO2019004636A2 (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN209727593U (zh) * 2019-03-15 2019-12-03 深圳市易瑞生物技术股份有限公司 一种检测前处理设备
KR102258937B1 (ko) * 2019-07-02 2021-06-01 주식회사 제놀루션 핵산 추출 장치 및 핵산 추출 장치의 구동 제어 방법
CN110408519A (zh) * 2019-09-04 2019-11-05 苏州达微致和基因科技有限公司 一种用于分子诊断的核酸提取装置
CN110923124B (zh) * 2020-02-17 2020-05-22 中国农业科学院蔬菜花卉研究所 用于磁珠法提取纯化核酸的仪器
KR102158793B1 (ko) * 2020-02-24 2020-09-23 주식회사 케이에이치메디칼 핵산 추출 장치
KR102526182B1 (ko) * 2021-03-31 2023-04-27 주식회사 제놀루션 핵산 또는 생물학적 물질의 추출장치 및 추출방법
KR102620858B1 (ko) * 2021-04-29 2024-01-04 주식회사 제놀루션 핵산추출장치 및 핵산추출장치에 사용되는 캡
EP4339618A1 (en) * 2021-05-13 2024-03-20 Autobio Labtec Instruments Co., Ltd. Magnetic attraction incubation mechanism of automatic molecular diagnostic instrument
WO2023041048A1 (zh) * 2021-09-17 2023-03-23 圣湘生物科技股份有限公司 自动核酸提取设备及其核酸提取方法
CN113984419B (zh) * 2021-10-15 2023-09-08 广州国睿科学仪器有限公司 一种核酸提取仪的装载状态及运动干涉检测方法和系统
CN113846007B (zh) * 2021-11-05 2022-07-08 广州国睿科学仪器有限公司 一种核酸提取仪的磁棒套安装机构
CN114371063B (zh) * 2021-12-23 2023-10-20 苏州睿康生物科技有限公司 一种全自动磁性固相萃取装置
KR102443820B1 (ko) * 2022-05-10 2022-09-16 주식회사 제놀루션 핵산추출장치

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100483684B1 (ko) * 2003-01-29 2005-04-18 (주)바이오넥스 핵산 또는 다양한 생물학적 물질을 분리 및 정제하기 위한키트와, 이러한 키트를 이용하여 생물학적 물질의 분리또는 정제 작업을 자동화하기 위한 시스템
WO2009125971A2 (ko) * 2008-04-09 2009-10-15 (주)바이오니아 자동정제장치, 멀티 웰 플레이트 키트 및 생물학적 시료로부터 핵산을 추출하는 방법
KR20130092185A (ko) * 2012-02-10 2013-08-20 (주)바이오니아 생체시료의 자동 분석 장치 및 방법
US20150079586A1 (en) * 2008-11-28 2015-03-19 Roche Molecular Systems, Inc. System and Method for Nucleic Acids Containing Fluid Processing
KR20160000001A (ko) * 2014-05-30 2016-01-04 주식회사 바이오포커스 자동 면역분석 수행장치
KR20160134542A (ko) * 2015-05-14 2016-11-23 바디텍메드(주) 일체화된 반응 및 검출 수단을 구비한 시험 장치에 사용되는 스테이션
US20170089936A1 (en) * 2015-09-30 2017-03-30 Accubiomed Co., Ltd Machine for automated extraction of nucleic acid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100483684B1 (ko) * 2003-01-29 2005-04-18 (주)바이오넥스 핵산 또는 다양한 생물학적 물질을 분리 및 정제하기 위한키트와, 이러한 키트를 이용하여 생물학적 물질의 분리또는 정제 작업을 자동화하기 위한 시스템
WO2009125971A2 (ko) * 2008-04-09 2009-10-15 (주)바이오니아 자동정제장치, 멀티 웰 플레이트 키트 및 생물학적 시료로부터 핵산을 추출하는 방법
US20150079586A1 (en) * 2008-11-28 2015-03-19 Roche Molecular Systems, Inc. System and Method for Nucleic Acids Containing Fluid Processing
KR20130092185A (ko) * 2012-02-10 2013-08-20 (주)바이오니아 생체시료의 자동 분석 장치 및 방법
KR20160000001A (ko) * 2014-05-30 2016-01-04 주식회사 바이오포커스 자동 면역분석 수행장치
KR20160134542A (ko) * 2015-05-14 2016-11-23 바디텍메드(주) 일체화된 반응 및 검출 수단을 구비한 시험 장치에 사용되는 스테이션
US20170089936A1 (en) * 2015-09-30 2017-03-30 Accubiomed Co., Ltd Machine for automated extraction of nucleic acid

Also Published As

Publication number Publication date
WO2019004636A2 (ko) 2019-01-03
KR20190001797A (ko) 2019-01-07

Similar Documents

Publication Publication Date Title
WO2019004636A3 (ko) 자동화된 핵산 분리 장치
CN204802656U (zh) 一种托盘分离装置
MX2018012499A (es) Flexion de hojas de vidrio.
EP4254287A3 (en) Automated parcel terminal
WO2014009801A3 (en) Cask transport assembly
MX2018001714A (es) Metodo y sistema para dar mantenimiento a un dispositivo de freno para operar junto con un disco de freno arreglado horizontalmente.
CN105013885A (zh) 一种新型钣金折弯机构
CN105818212A (zh) 一种塑料冲孔机架
MX2017005780A (es) Metodo para dividir placa de vidrio y dispositivo divisor para el mismo.
MX2017015448A (es) Dispositivo de colada.
CN104874648A (zh) 一种改进型钣金折弯机构
CN202290882U (zh) 一种模具板料的到位检测装置
WO2013127802A3 (de) Isolationsträger für eine stromschiene für elektrisch getriebene schienenfahrzeuge
MY156953A (en) Method of manufacturing glass blank, method of manufacturing magnetic recording medium substrate, and method of manufacturing magnetic recording medium
CN104333303A (zh) 一种具有前后限位功能的太阳能电池板安装架
CN203875172U (zh) 一种中厚板工件翻转机构
CN102632108A (zh) Led显示屏背板整平治具
CN104986570A (zh) 一种可升降并夹紧零件的定位机构
CN107152920A (zh) 汽车天窗玻璃自动检测装置
CN204223459U (zh) 一种平板玻璃竖放型l架
CN104201976B (zh) 一种太阳能电池板安装架
CN203945439U (zh) 木材加工提升装置
CN206702942U (zh) 多重集聚纺底座等高定位安装工具
CN204052559U (zh) 一种连续模具斜冲孔装置
CN105731124A (zh) 一种车门内板定位装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 18823487

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 18823487

Country of ref document: EP

Kind code of ref document: A2