WO2015146759A1 - Récipient médical - Google Patents

Récipient médical Download PDF

Info

Publication number
WO2015146759A1
WO2015146759A1 PCT/JP2015/058160 JP2015058160W WO2015146759A1 WO 2015146759 A1 WO2015146759 A1 WO 2015146759A1 JP 2015058160 W JP2015058160 W JP 2015058160W WO 2015146759 A1 WO2015146759 A1 WO 2015146759A1
Authority
WO
WIPO (PCT)
Prior art keywords
medical container
container
liquid
seal
container body
Prior art date
Application number
PCT/JP2015/058160
Other languages
English (en)
Japanese (ja)
Inventor
糸瀬一徳
山口剛之
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to JP2016510279A priority Critical patent/JP6564766B2/ja
Publication of WO2015146759A1 publication Critical patent/WO2015146759A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A61J7/0445—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system for preventing drug dispensing during a predetermined time period
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0454—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for dispensing of multiple drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A61J7/049—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis automatically changing in response to a schedule deviation by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/30—Printed labels
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers

Definitions

  • the present invention relates to a medical container having a container body formed by welding two sheets into a bag shape.
  • a medical container (so-called soft bag) having a container body formed as a bag by bonding two flexible resin sheets by welding as a kind of medical container such as a chemical container or an infusion container Is known (see, for example, Japanese Patent Laid-Open No. 8-155009).
  • the sheet constituting the container body of the soft bag is made of a material having transparency so that the remaining liquid amount of the content liquid filled in the container body can be visually recognized.
  • the scale which shows the amount of residual liquid is normally attached
  • two sheets constituting the container body may stick to each other in the container body.
  • the two sheets are close to each other when the content liquid is filled in the container body, so that the two sheets are stuck to each other during drainage.
  • the liquid level is curved at the sticking point, making it unclear where the liquid level is in relation to the scale, and as a result It becomes difficult to grasp the remaining liquid amount.
  • the present invention has been made in consideration of such a problem, and a medical container capable of suppressing a decrease in liquid level visibility at the time of draining without accompanying an increase in the remaining amount of space more than necessary.
  • the purpose is to provide.
  • the present invention provides a container main body having a seal portion in which two sheets are welded to each other and formed in a bag shape and extending in a circular shape along the outer edge of the liquid storage portion,
  • a medical container comprising a mouth provided at one end of a container body and a liquid contained in the container body, wherein the seal part is a first seal formed on the mouth side. Part, a second seal part formed on the opposite side of the mouth part, and a pair of side seal parts extending between the first seal part and the second seal part,
  • the side seal portion is provided with a bulging portion that bulges toward the inside of the container body, and the medical container is heat sterilized.
  • the side seal portion is provided with the bulging portion so that both side portions of the liquid storage portion of the container body are constricted.
  • the sheet is distorted due to shrinkage anisotropy during cooling after the sealing process (after welding) in the manufacturing process, and the sheets are difficult to stick to each other.
  • sticking of sheets to each other is suppressed at the time of filling the container main body with the liquid in the manufacturing process, and as a result, an appropriate remaining amount is ensured without additionally injecting air.
  • the sheets are further distorted, and the difficulty of sticking between the sheets is enhanced. Therefore, sticking of sheets near the liquid surface is suppressed during drainage (during use), and liquid surface visibility is ensured, so that the remaining liquid amount can be easily grasped.
  • the bulging portion may be provided at a substantially central portion in the extending direction of the side seal portion.
  • Said medical container WHEREIN Each inner side outline of the part between the said bulging part and the said 1st seal part, and the part between the said bulging part and the said 2nd seal part among the said side seal parts.
  • the shape may have a straight line.
  • This configuration makes it possible to minimize the decrease in the remaining amount of air due to the provision of the bulging portion.
  • the inner contour shape of the bulging portion may be formed in an arc shape.
  • the seal width of the portion where the bulging portion is formed in the side seal portion may be larger than the seal width of the other portion.
  • the outer contour shape of the bulging portion may be linear.
  • the amount of the liquid may be 200 mL or less.
  • the medical container of the present invention it is possible to suppress a decrease in the liquid level visibility during drainage without accompanying an increase in the remaining amount of space more than necessary.
  • FIG. 1 is an overall perspective view of a medical container according to an embodiment of the present invention. It is a top view of the medical container shown in FIG. It is explanatory drawing of the use condition of the medical container shown in FIG.
  • FIG. 4A is a graph showing a test result for an example of the present invention
  • FIG. 4B is a graph showing a test result for a comparative example.
  • FIG. 1 is an overall perspective view of a medical container 10 according to an embodiment of the present invention.
  • the medical container 10 includes a bag-shaped container main body 12 having a liquid chamber 13 therein, a mouth portion 14 attached to the lower end portion of the container main body 12, a plug 16 disposed inside the mouth portion 14, And a film 18 welded to the mouth portion 14.
  • the medical container 10 is a container in which the container body 12 is constituted by a flexible and transparent resin sheet 20 and is a so-called soft bag.
  • a predetermined liquid 21 is stored in the liquid chamber 13 of the container body 12 in advance.
  • the liquid 21 accommodated in the liquid chamber 13 include physiological saline, electrolyte solution, Ringer's solution, high calorie infusion, glucose solution, water for injection, amino acid preparation, pain relieving agent, antiemetic, blood flow improving agent, free radical.
  • Examples include a remover.
  • the container body 12 is composed of two sheets 20 (20a, 20b) welded at the seal portion 24.
  • the container body 12 includes a liquid storage portion 26 that forms the liquid chamber 13 and a seal portion 24 that extends in a circular shape along the outer edge of the liquid storage portion 26.
  • the seal portion 24 includes a first seal portion 31 formed on the mouth portion 14 side (lower side), a second seal portion 32 formed on the side opposite to the mouth portion 14 (upper side), and a first seal portion. 31 and a pair of side seal portions 34 extending between the second seal portions 32.
  • the first seal portion 31 and the second seal portion 32 are portions of the seal portion 24 that extend in the width direction of the medical container 10.
  • the first seal portion 31 is located on both sides of the mouth portion 14.
  • the second seal portion 32 is located on the opposite side of the first seal portion 31 with respect to the liquid storage portion 26.
  • the pair of side seal portions 34 extend along the center line C of the container main body 12 between both ends of the first seal portion 31 and the second seal portion 32. Both ends of each side seal portion 34 are connected to the first seal portion 31 and the second seal portion 32.
  • Each side seal portion 34 is provided with a bulging portion 36 that bulges toward the center line C side (inward) of the container body 12, so that the liquid storage portion 26 is located at the center in the height direction. It has a shape with a narrowed part.
  • the bulging portion 36 is provided at a substantially central portion in the extending direction of the side seal portion 34.
  • the inner contour shape of the bulging portion 36 is formed in an arc shape (arc shape). That is, the bulging portion 36 is not provided with a sharp top.
  • the radius of curvature R of the inner contour shape of the bulging portion 36 is set to 20 to 450 mm, for example.
  • the outer contour shape of the bulging portion 36 is formed in a straight line shape.
  • the outer contour shape of the side seal portion 34 is linear across the bulging portion 36 and the straight portions 38 on both sides thereof.
  • the length A of the bulging portion 36 is shorter than the length L between the first seal portion 31 and the second seal portion 32.
  • the height B of the bulging portion 36 from the straight portion 38 is too small, the amount of distortion due to the shrinkage anisotropy of the sheet 20 at the time of cooling after heating, which will be described later, is insufficient, and the sheet 20 is stuck on the liquid storage portion 26. Difficult to get bitter.
  • the height B of the bulging portion 36 is too large, the effective internal volume of the container body 12 is reduced accordingly, so that the remaining amount in the container body 12 is reduced too much.
  • the height B of the bulging portion 36 is smaller than the distance W between the straight portion 38 and the center line C of the container body 12.
  • the ratio of the height B of the bulging portion 36 and the distance W between the straight portion 38 and the center line C of the container body 12 is set to, for example, 1:50 to 1: 1.5. Further, the ratio between the length A of the bulging portion 36 and the height B of the bulging portion 36 is set to 2: 1 to 60: 1, for example.
  • the outer contour shape of the side seal portion 34 is linear, and the bulging portion 36 protrudes toward the center line C side of the container body 12 with respect to the straight portion 38.
  • the seal width W1 of the bulging part 36 is larger than the seal width W2 of the other part (straight part 38) of the side seal part 34.
  • the scale part 40 which shows the liquid quantity of a content liquid is provided in the outer surface of the liquid storage part 26 of the container main body 12. As shown in FIG. In the case of the medical container 10 according to the present embodiment, the scale part 40 includes a plurality of scale lines 41 arranged at intervals along the length direction of the container body 12 (extending direction of the side seal part 34). Have. When draining the liquid, if the medical container 10 is hung and the mouth part 14 is directed downward, the liquid level of the content liquid (liquid 21) can be visually recognized through the transparent container body 12, and the liquid level and scale part. From the positional relationship with 40, the remaining liquid amount can be grasped.
  • the upper end of the container body 12 is provided with a hole 28 into which a hook portion 48 (see FIG. 3) provided on a hanger or the like can be inserted.
  • the medical container 10 can be hung on the hanger or the like by being hooked on the hanger or the like at the hole 28.
  • sheet 20 As a constituent material of the container body 12 (sheet 20), for example, polyolefin (eg, polyethylene, polypropylene, polybutene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, ionomer, or a mixture of two or more of these) ), Polyvinyl chloride, polyamide, polyimide, or a multilayer sheet of the above two or more polymer materials.
  • polyolefin eg, polyethylene, polypropylene, polybutene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, ionomer, or a mixture of two or more of these
  • Polyvinyl chloride polyamide, polyimide, or a multilayer sheet of the above two or more polymer materials.
  • a material in which distortion of the sheet 20 due to shrinkage anisotropy is effectively generated at the time of cooling after heating in the sealing process and the heat sterilization process of the manufacturing process That is, it is preferable to employ a material having a large shrinkage ratio at the time of cooling after heating.
  • materials include polypropylene, ethylene-vinyl acetate copolymer, polyethylene, polyvinyl chloride and the like.
  • the mouth part 14 connected to the lower end part of the container body 12 is a part forming a fluid inlet / outlet.
  • the mouth portion 14 is a hollow cylindrical member (in this embodiment, a hollow cylindrical shape) whose both ends are open.
  • the constituent material of the mouth portion 14 include hard resins such as polypropylene, polyethylene, ABS resin, polycarbonate, and acrylic resin.
  • the plug 16 fixed to the mouth part 14 is a member that seals the mouth part 14 in an airtight and liquid-tight manner.
  • the stopper 16 can pierce the needle provided on the syringe and the bottle needle 54 (see FIG. 3) provided on the infusion line 50, and can be liquid-tight after the needle and bottle needle 54 are removed. It is made of an elastic material so that airtightness can be maintained. That is, the plug body 16 is a so-called rubber plug.
  • Examples of the constituent material of the plug body 16 include various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, and polyurethane, polyester, polyamide, olefin, and styrene. Examples thereof include various thermoplastic elastomers such as systems, or mixtures thereof.
  • the film 18 is releasably welded to the end of the mouth portion 14, and the surface of the plug body 16 is covered with the film 18, thereby depending on the external environment. Contamination of the plug 16 is prevented.
  • the film 18 is peeled from the mouth portion 14.
  • the two sheets 20a and 20b are obtained by applying pressure and heating the two resin sheets 20 (material sheets) superimposed on each other with a mold having a pressing surface having a shape corresponding to the seal portion 24.
  • the seal portions 24 are formed by welding them together. Or the sheet
  • the mouth 14 is attached to the container body 12 by an appropriate joining method such as adhesion or welding.
  • a predetermined amount of liquid 21 is filled into the container body 12 through the mouth portion 14 with the mouth portion 14 facing upward.
  • the filling amount of the liquid 21 into the container body 12 is such that air remains in the container body 12 after filling.
  • the container body 12 it is difficult for the sheets 20 a and 20 b to stick to each other before the liquid 21 is filled, so that the liquid 21 is in a state where the sheets 20 a and 20 b of the liquid storage unit 26 are stuck to each other. Will not be filled. Therefore, the effective internal volume as designed can be used, and the remaining amount of space can be prevented from being reduced due to sticking between the sheets 20a and 20b.
  • the plug 16 is attached to the mouth 14 to seal the mouth 14.
  • the film 18 is affixed on the edge part of the opening
  • heat sterilization treatment is performed on the medical container 10.
  • the heat sterilization treatment include autoclave sterilization at 121 ° C. for 20 minutes.
  • the sheet 20 constituting the container body 12 contracts upon cooling after heating.
  • distortion of the sheet 20 due to shrinkage anisotropy occurs along the shape of the bulging portion 36. Therefore, even if the sheet 20 is distorted at this time, it is difficult for the sheets 20a and 20b to stick to each other.
  • the flexibility of the sheet 20 constituting the medical container 10 is reduced (the rigidity is increased) through the heating and cooling by the heat sterilization process, the shape maintaining force of the sheet 20 in a distorted state is increased. Further, the difficulty of sticking between the sheets 20a and 20b is more easily exhibited.
  • the medical container 10 according to the present embodiment is basically configured as described above, and the operation and effect thereof will be described below.
  • the bottle needle 54 provided at the end of the infusion line 50 (end of the infusion tube 52) is pierced through the plug body 16 and provided on the hanger or the like.
  • the medical container 10 By hooking the medical container 10 on the hook portion 48 at the position of the hole 28, the medical container 10 is suspended with the mouth portion 14 facing downward.
  • the lumen of the infusion line 50 communicates with the inside of the liquid storage portion 26 (liquid chamber 13) of the container body 12.
  • the liquid 21 is discharged from the medical container 10 and supplied to the patient via the infusion line 50.
  • the amount of liquid remaining in the medical container 10 can be grasped from the positional relationship between the liquid level Lv1 of the liquid 21 seen through the transparent container body 12 and the scale portion 40 provided on the container body 12. it can.
  • the sheets 20 a and 20 b near the liquid surface are attached to each other due to the effect of the bulging part 36 (constriction of the liquid storage part 26) of the side seal part 34. Since the sticking is suppressed, the liquid level Lv1 of the liquid 21 is horizontal (straight) over the width direction of the liquid container 26. For this reason, it is easy to understand the positional relationship between the liquid level Lv1 and the scale portion 40, and it is easy to grasp the remaining liquid amount.
  • the sheet 20 is distorted by shrinkage anisotropy during the sealing process in the manufacturing process (when the sheets 20a and 20b are welded together). Does not occur.
  • a sticking portion S1 between the sheets 20a and 20b is generated in the vicinity of the side seal portion 34. Cheap.
  • the amount of remaining space in the container body 12 after filling the liquid 21 is reduced by the amount that the effective internal volume of the container body 12 is reduced. Is likely to stick.
  • the sheet 20 is not distorted due to the shrinkage anisotropy during the heat sterilization process in the manufacturing process. For this reason, for example, as shown by an imaginary line in FIG. 3, a sticking portion S ⁇ b> 2 between the sheets 20 a and 20 b near the liquid surface is likely to occur during drainage. When such a sticking portion S2 occurs during drainage, a curved liquid level Lv2 appears. In the case of the curved liquid level Lv2, it is difficult to understand the positional relationship with the scale portion 40, so it is difficult to grasp the remaining liquid amount.
  • the constituent material of the container body is polypropylene
  • the sheet thickness is 250 ⁇ m
  • the welding conditions of the sheet are welding temperature 215 ° C., welding time 2 seconds, pressure 0.3 MPa
  • contents The liquid was 106 mL (city water).
  • the side seal portion is provided with a bulge portion
  • the height of the bulge portion is 2 mm
  • the internal size of the liquid storage portion is 92 mm at the location of the straight portion, It was set to 88 mm at the location.
  • the comparative example there was no bulging part, and the internal dimension of the liquid storage part was 92 mm.
  • FIG. 4A is a graph showing the test results regarding the state of generation of the remaining amount after filling the container main body (before heat sterilization treatment), and FIG.
  • Table 1 below is a table showing the test results regarding the state of sticking between sheets in the vicinity of the liquid surface at the time of drainage, with respect to Examples of the present invention, and Table 2 below for Comparative Examples.
  • A indicates that there is no sticking between sheets near the liquid level
  • B indicates that there is sticking between sheets near the liquid level.
  • the specimen having a remaining amount of 16 mL or more is near the liquid surface until the end of drainage. There was no sticking between the sheets. That is, under the conditions of this test, the minimum required remaining amount that does not cause sticking between sheets near the liquid level was 16 mL or more in the present invention, whereas it was 25 mL or more in the comparative example. From this, it is understood that the present invention has an effect of suppressing the sticking between the sheets near the liquid level without increasing the remaining amount more than necessary as compared with the comparative example.
  • the side seal portion 34 is provided with the bulging portion 36 so that both side portions of the liquid storage portion 26 of the container body 12 are constricted. It has become.
  • the sheet 20 is distorted due to shrinkage anisotropy during cooling after the sealing process (after welding) in the manufacturing process, and the sheets 20a and 20b are difficult to stick to each other. Thereby, sticking of the sheets 20a and 20b to each other is suppressed when the container 21 is filled with the liquid 21 in the manufacturing process, and as a result, an appropriate remaining amount is secured.
  • the sheet 20 is further distorted, and the difficulty of sticking between the sheets 20a and 20b is enhanced. Accordingly, the sheets 20a and 20b in the vicinity of the liquid level are prevented from sticking to each other at the time of draining (in use), and the liquid level visibility is ensured, so that the remaining liquid amount can be easily grasped.
  • the amount of the liquid 21 accommodated in the container main body 12 is 200 mL or less, since the distance between the two sheets 20a and 20b is short, it is particularly effective to provide the bulging portion 36.
  • the bulging portion 36 is provided at a substantially central portion in the extending direction of the side seal portion 34, so that the distortion of the sheet 20 due to shrinkage anisotropy is substantially the entire extending direction of the side seal portion 34. And the sticking between the sheets 20a and 20b in the vicinity of the liquid level at the time of drainage can be more suitably suppressed.
  • each inner contour shape of the portion between the bulging portion 36 and the first seal portion 31 and the portion between the bulging portion 36 and the second seal portion 32 in the side seal portion 34. Is linear, it is possible to reduce the reduction in the remaining amount of air due to the provision of the bulging portion 36 as much as possible.
  • the inner contour shape of the bulging portion 36 is formed in an arc shape.
  • the seal width W1 of the portion where the bulging portion 36 is formed in the side seal portion 34 is larger than the seal width W2 of the other portion (straight portion 38), and therefore the sealing process in the manufacturing process.
  • the seal width W1 of the portion where the bulging portion 36 is formed in the side seal portion 34 is larger than the seal width W2 of the other portion (straight portion 38), and therefore the sealing process in the manufacturing process.
  • the outer contour shape of the bulging portion 36 is linear, it depends on the shrinkage anisotropy at the time of cooling after heating during the sealing process (at the time of welding) or the heat sterilization process in the manufacturing process.
  • the distortion of the sheet 20 can be obtained effectively.

Abstract

Dans la présente invention, le corps de récipient (12) d'un récipient médical (10) est formé par soudage de deux feuilles (20) l'une à l'autre dans une forme de sac. La section de scellement (24) du corps de récipient (12) possède une première section de scellement (31) formée sur le côté de la bouche (14), une seconde section de scellement (32) formée sur le côté opposé de la bouche (14), et une paire de sections latérales de scellement (34) s'étendant entre la première section de scellement (31) et la seconde section de scellement (32). Chacune des sections latérales de scellement (34) est pourvue d'une protubérance (36) faisant saillie vers l'intérieur du corps de récipient (12). Le récipient médical (10) est stérilisé par chauffage.
PCT/JP2015/058160 2014-03-27 2015-03-19 Récipient médical WO2015146759A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2016510279A JP6564766B2 (ja) 2014-03-27 2015-03-19 医療用容器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014065241 2014-03-27
JP2014-065241 2014-03-27

Publications (1)

Publication Number Publication Date
WO2015146759A1 true WO2015146759A1 (fr) 2015-10-01

Family

ID=54195280

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2015/058160 WO2015146759A1 (fr) 2014-03-27 2015-03-19 Récipient médical

Country Status (2)

Country Link
JP (1) JP6564766B2 (fr)
WO (1) WO2015146759A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009153588A (ja) * 2007-12-25 2009-07-16 Jms Co Ltd 医療用容器及び医療用容器セット
JP2009542367A (ja) * 2006-06-28 2009-12-03 ホスピラ・インコーポレイテツド 医療流体容器
EP2193775A1 (fr) * 2008-12-08 2010-06-09 Technoflex Récipient souple à usage médical

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4387761B2 (ja) * 2003-10-31 2009-12-24 扶桑薬品工業株式会社 フィルムバッグ
JP4583852B2 (ja) * 2004-09-21 2010-11-17 株式会社細川洋行 医療用容器

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009542367A (ja) * 2006-06-28 2009-12-03 ホスピラ・インコーポレイテツド 医療流体容器
JP2009153588A (ja) * 2007-12-25 2009-07-16 Jms Co Ltd 医療用容器及び医療用容器セット
EP2193775A1 (fr) * 2008-12-08 2010-06-09 Technoflex Récipient souple à usage médical

Also Published As

Publication number Publication date
JPWO2015146759A1 (ja) 2017-04-13
JP6564766B2 (ja) 2019-08-21

Similar Documents

Publication Publication Date Title
US6241717B1 (en) Single use universal access device/medical container combination
US4516977A (en) Storage bag
US6287289B1 (en) Multiple use universal connector
KR101510084B1 (ko) 복실 용기
JP2016525396A (ja) 医療用液体用のアンプル及びアンプルを製造する方法
JP6256352B2 (ja) 血液成分分離収容装置及び多血小板血漿の調製方法
US3368560A (en) Outlet fitting for plastic parenteral solution container
US20090105684A1 (en) Medication port for medical fluid container
JP2017516570A (ja) 医療用流体の投与用のドリップチャンバー
JP6564766B2 (ja) 医療用容器
KR20180037071A (ko) 침 부착 접속 부재, 약제 용해 키트
JP7367179B2 (ja) 袋状容器及びその製造方法
JP4366131B2 (ja) 複室容器
JP7021303B2 (ja) 医療用バッグの製造方法
JP3130547B2 (ja) 血液バッグ
KR100780407B1 (ko) 가역성 1회용 혈관 수지침 및 스포이드부를 갖는수액공급장치
JP4066222B2 (ja) 自動開閉弁付コネクターおよびそれを用いた医療用具
WO2016196632A1 (fr) Accessoire à deux accès pour contenant
JP4365948B2 (ja) 輸液バッグ
JP2000262589A (ja) 複室容器
CN210904111U (zh) 一种一次性使用输血袋封闭塞
JP6377133B2 (ja) 採血用器具および採血用器具の製造方法
JP2009542367A (ja) 医療流体容器
CN2717433Y (zh) 软袋输液塞
JP5223562B2 (ja) 血液成分調製用容器及び血液成分分離収容装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 15767765

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2016510279

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 15767765

Country of ref document: EP

Kind code of ref document: A1