WO2015079750A1 - Dispositif de stérilisation à faisceau d'électrons - Google Patents

Dispositif de stérilisation à faisceau d'électrons Download PDF

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Publication number
WO2015079750A1
WO2015079750A1 PCT/JP2014/071695 JP2014071695W WO2015079750A1 WO 2015079750 A1 WO2015079750 A1 WO 2015079750A1 JP 2014071695 W JP2014071695 W JP 2014071695W WO 2015079750 A1 WO2015079750 A1 WO 2015079750A1
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WO
WIPO (PCT)
Prior art keywords
container
electron beam
control unit
nozzle
mouth
Prior art date
Application number
PCT/JP2014/071695
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English (en)
Japanese (ja)
Inventor
細川　徹
洋平 寺坂
Original Assignee
日立造船株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日立造船株式会社 filed Critical 日立造船株式会社
Publication of WO2015079750A1 publication Critical patent/WO2015079750A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/087—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/08—Sterilising wrappers or receptacles prior to, or during, packaging by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K5/00—Irradiation devices
    • G21K5/04—Irradiation devices with beam-forming means

Definitions

  • the present invention particularly relates to an electron beam sterilization apparatus for sterilizing the inner surface of a container or the like with an electron beam.
  • An electron beam sterilization apparatus for sterilizing the inner surface of a container such as a bottle with an electron beam is generally a nozzle that emits an electron beam from the tip, and a container holder that is disposed below the nozzle and can be raised and lowered. And an elevating mechanism for elevating and lowering the container holder.
  • the container is held by the container holder so that the mouth of the container faces upward, and the container is lifted by the lifting mechanism to insert the nozzle into the mouth of the container.
  • the electron beam sterilization apparatus sterilizes the inside of the container B by emitting an electron beam e from the tip of the nozzle n inserted into the mouth m of the container B.
  • the container B that can be handled by the conventional electron beam sterilization apparatus is not limited to the “shoulder shoulder” or the shoulder portion s close thereto, but is limited to the one having the “sloping shoulder” shoulder portion s. It was. Therefore, the container B inevitably has a problem that its volume is small.
  • an object of the present invention is to provide an electron beam sterilization apparatus that can appropriately sterilize a container having a large volume shape.
  • an electron beam sterilization apparatus includes a container holding unit that holds a container, and an electron beam irradiation that irradiates an electron beam inside the container held by the container holding unit.
  • An electron beam sterilization apparatus comprising: An operation control unit for controlling the operation of the container held by the container holding unit; An attitude control unit for controlling the attitude of the container held by the container holding unit, The operation control unit and the posture control unit control the operation and the posture of the container so that the inner surface of the container is irradiated with the electron beam substantially evenly.
  • An electron beam sterilization apparatus is the electron beam sterilization apparatus according to claim 1, wherein the electron beam irradiation unit emits an electron beam from a tip portion inserted into a mouth portion of the container.
  • a nozzle The operation of the container controlled by the operation control unit is rotation of the container around the mouth of the container, The attitude of the container controlled by the attitude control unit is a state in which the axis of the trunk of the container is inclined with respect to the axis of the nozzle.
  • the electron beam sterilization apparatus is the electron beam sterilization apparatus according to claim 2, wherein the container holding part is disposed on the outer periphery of the mouth part of the container, and the outer diameter of the mouth part is larger.
  • a holding elastic ring having a large inner diameter, a fixed body to which the holding elastic ring is fixed, and reducing the diameter of the holding elastic ring with a compression fluid, so that the holding elastic ring holds the mouth portion.
  • the operation control unit has an endless belt hung on the fixed body, and a motor capable of circulatingly driving the endless belt,
  • the posture control unit has a drive mechanism that can tilt the fixed body.
  • An electron beam sterilization apparatus is the electron beam sterilization apparatus according to claim 1, wherein the electron beam irradiation unit emits an electron beam from a tip portion inserted into a mouth portion of the container.
  • a nozzle The operation of the container controlled by the operation control unit is the withdrawal of the nozzle with respect to the mouth of the container,
  • the attitude of the container controlled by the attitude control unit is a state in which the axis of the trunk of the container is inclined with respect to the axis of the nozzle.
  • the electron beam sterilization method according to claim 5 of the present invention is an electron beam sterilization method for sterilizing the inside of a container with an electron beam emitted from the tip of a nozzle, An inclining step for inclining the axis of the barrel of the container with respect to the axis of the nozzle; An insertion step of inserting the tip of the nozzle into the mouth of the container; A rotation step of rotating the container around the mouth of the container, The tilting and rotation causes the inner surface of the container to be irradiated with an electron beam substantially evenly.
  • a container having a large volume can be appropriately sterilized.
  • FIG. 1 is a schematic configuration diagram of an electron beam sterilization apparatus according to an embodiment of the present invention. It is a front view of the same electron beam sterilizer. It is a figure which shows the to-be-lifted body of the same electron beam sterilization apparatus, FIG. 3A is a top view, FIG. 3B is AA sectional drawing of FIG. 3A. It is an expanded front sectional view which shows the vicinity of the opening
  • FIG. 5 is a sectional view taken along line BB in FIG. 4. It is a front view after the inclination process of the same electron beam sterilizer.
  • FIG. 11A is an enlarged front view for explaining sterilization of a container by a conventional electron beam sterilization apparatus, FIG. 11A shows sterilization of a container close to an “anchoring shoulder”, and FIG. The simulation result of the electron beam radiate
  • the electron beam sterilization apparatus described below is a so-called ITB (In the Bottle) type for sterilizing the inside of a container.
  • ITB In the Bottle
  • the electron beam sterilization apparatus 1 has a configuration common to that of the conventional one, a container holding unit 2 that holds a container B, and an electron inside the container B held by the container holding unit 2.
  • an electron beam irradiation unit 3 for irradiating a line.
  • the electron beam irradiation unit 3 includes a nozzle n that emits an electron beam from a tip t inserted into the mouth m of the container B.
  • the electron beam sterilization apparatus 1 includes, as a gist of the present invention, an operation control unit 4 that controls the operation of the container B held by the container holding unit 2 and the container B held by the container holding unit 2. And a posture control unit 5 that controls the posture.
  • the operation control unit 4 and the posture control unit 5 control the operation and the posture of the container B so that the electron beam is irradiated almost uniformly on any part of the inner surface of the container B.
  • the above-mentioned substantially equal does not mean perfect equality, but means that even non-uniformity that does not generate an insufficient or excessive portion of electron beam irradiation is allowed.
  • the above-described substantially uniform electron beam irradiation means that an insufficiently sterilized portion does not occur on the inner surface of the container B, and a portion where the material deteriorates due to the electron beam irradiation does not occur.
  • movement is rotation of the said container B centering on the opening
  • the posture is a state in which the axial center Cb of the body portion b in the container B is inclined with respect to the axial center Cn of the nozzle n (precisely the tip portion t).
  • the electron beam sterilization apparatus 1 has a configuration common to the conventional one, and an elevating unit 6 (e.g., FIG. See also).
  • the elevating unit 6 includes an elevating / holding plate 61 that holds the body to be lifted and has a U-shape in plan view, and a sliding body attached to the elevating / holding plate 61. 62, a linear slider 63 that can guide the sliding body 62 up and down, and a lifting drive device (not shown) that moves the sliding body 62 up and down to raise and lower the lifting holding plate 61.
  • the electron beam irradiation unit 3 has an electron beam generator 31 that generates an electron beam emitted from the nozzle n in addition to the nozzle n described above.
  • the electron beam irradiation unit 3 is arranged such that the tip end t of the nozzle n is vertically downward.
  • the electron beam irradiation unit 3 is configured to irradiate the electron beam generated by the electron beam generator 31 vertically downward from the tip t of the nozzle n. Needless to say, as described in FIG. 11 as the background art, the electron beam emitted vertically downward spreads to the side.
  • the container holding part 2 is disposed on the outer periphery of the mouth part m in the container B and has a grip rubber 21 (holding elastic ring) having an inner diameter larger than the outer diameter of the mouth part m, A rotating fixed body 22 (fixed body) to which the grip rubber 21 is fixed, and a pneumatic device group 26 that supplies compressed air (an example of compressed fluid) to the grip rubber 21 are provided.
  • a grip rubber 21 holding elastic ring
  • a rotating fixed body 22 fixed body to which the grip rubber 21 is fixed
  • a pneumatic device group 26 that supplies compressed air (an example of compressed fluid) to the grip rubber 21 are provided.
  • the grip rubber 21 has a configuration (elasticity and shape) capable of holding the mouth m on the inner periphery by reducing the diameter when compressed air is supplied to the outer periphery.
  • the grip rubber 21 is formed in a thin film shape along the mouth m at the middle portion while keeping the air tightness with the rotating fixed body 22 at the upper and lower portions over the entire circumference.
  • the rotating fixed body 22 has a substantially cylindrical shape with a through-hole 23 formed in the center.
  • the through-hole 23 is a space in which the mouth m in the container B can be inserted from below and the nozzle n can be inserted from above.
  • a circumferential space portion 24 that fixes the grip rubber 21 and receives compressed air on the outer peripheral side of the grip rubber 21 is formed on the inner periphery of the rotating fixed body 22.
  • the rotary fixed body 22 is formed with a large number of inner communication passages 25 communicating radially from the outer peripheral surface thereof to the circumferential space portion 24 in a plan view. These inner communication passages 25 guide the compressed air from the circumferential groove 42 (described later in detail) of the housing 41 to the circumferential space 24.
  • the pneumatic device group 26 generates compressed air and supplies it to the grip rubber 21 (exactly the circumferential space portion 24) and the air cylinder 53 (details will be described later).
  • a pneumatic pump an example of a fluid supplier
  • a pneumatic circuit that guides compressed air
  • valves that control the flow of the compressed air.
  • the container holding part 2 receives the compressed air supplied from the pneumatic device group 26 in the circumferential space part 24 and reduces the diameter of the grip rubber 21 (particularly a thin film-like intermediate part). In this configuration, the mouth m of the container B is held by the grip rubber 21.
  • the operation control unit 4 includes a housing 41 that rotatably supports the rotating fixed body 22, an endless belt 45 that is hung on the outer periphery of the rotating fixed body 22, and the endless belt 45. And a motor 46 that can be circulated.
  • the housing 41 is provided with a bearing 43 on the inner peripheral side thereof, so that the rotating fixed body 22 can rotate around the axis of the mouth portion m in the container B. .
  • a circumferential groove 42 is formed on the inner periphery of the housing 41 at a position corresponding to the inner communication path 25.
  • the housing 41 is formed with an outer communication path that communicates from the outer peripheral surface to the circumferential groove 42.
  • the outer communication path guides compressed air from the pneumatic device group 26 to the circumferential groove 42.
  • the motor 46 is attached to the housing 41 via a fixed plate 49 so that the shaft 47 thereof is parallel to the rotational axis of the rotating fixed body 22.
  • a concentric pulley 48 is attached to the shaft 47 of the motor 46.
  • the endless belt 45 is hung on the outer circumferences of the pulley 48 and the rotating fixed body 22 and transmits the rotation of the shaft 47 of the motor 46 to the rotating fixed body 22.
  • the operation control unit 4 rotates the rotating fixed body 22 through the pulley 48 and the endless belt 45 by the rotation of the shaft 47 of the motor 46, and the container B held on the grip rubber 21 together with the rotating fixed body 22. Is also configured to rotate.
  • attitude control unit 5 projects horizontally from the housing 41 and is rotatably supported by the elevation holding plate 61 of the elevation unit 6, and rotates the shaft 51.
  • an air cylinder an example of a drive mechanism 53 connected to the lever plate 52.
  • At least one of the shafts 51 has one end fixed to the housing 41 and the other end fixed to the lever plate 52 as shown in FIG.
  • the shaft 51 is rotatably supported by the lift holding plate 61 by a bearing 55 disposed inside a hole penetrating the lift holding plate 61.
  • the lever plate 52 has one end fixed perpendicularly to the shaft 51 and the other end connected to the piston rod 54 of the air cylinder 53.
  • the cap side of the air cylinder 53 is connected to the lift holding plate 61.
  • the air cylinder 53 is connected to the pneumatic device group 26 and causes the piston rod 54 to move out and with the compressed air from the pneumatic device group 26.
  • the posture control unit 5 rotates the shaft 51 via the lever plate 52 by the withdrawal and withdrawal of the piston rod 54 and tilts the housing 41 along with this rotation, and is held by the grip rubber 21 together with the housing 41.
  • the container B is also inclined.
  • the object to be lifted (moved up and down by the lifting unit 6) includes the container B, the container holding unit 2 (excluding the pneumatic device group 26), the operation control unit 4, and the attitude control. Part 5. Further, what is inclined by the attitude control unit 5 is the container B, the container holding unit 2 (excluding the pneumatic device group 26), and the operation control unit 4.
  • the usage method (electron beam sterilization method) of the said electron beam sterilizer 1 is demonstrated based on drawing.
  • the mouth m in the container B is held by the container holding part 2.
  • the container B is tilted by the attitude control unit 5 until the axis Cb of the body b of the container B is at a predetermined angle ⁇ with respect to the axis Cn of the nozzle n (inclination process). Is).
  • the elevating unit 6 causes the tip portion t of the nozzle n to be in the mouth m in the container B.
  • the object to be lifted is raised until it is inserted (this is an insertion process).
  • FIG. 8 in FIG.
  • the configuration other than the container B and the nozzle n is omitted
  • the electron beam irradiation unit 3 emits the electron beam e from the tip t of the nozzle n.
  • the operation controller 4 rotates the container B around the axis of the mouth m (rotating process).
  • the predetermined angle ⁇ and the rotation speed are such that the inner surface of the container B is irradiated with the electron beam e substantially evenly. For this reason, as shown in FIG. 8, the shoulder part s which became the lower side by the inclination is sufficiently irradiated with the electron beam e.
  • the shoulder s that is on the upper side due to the inclination seems not to be sufficiently irradiated with the electron beam e.
  • the shoulder s becomes the lower side due to the rotation, and as a result, the electron beam e is sufficiently irradiated.
  • the electron beam sterilization apparatus 1 is also used for a container B1 in which the distance between the axis of the mouth m and the shoulder s or the trunk b in the vertical cross section of the axis is not constant. Suitable for sterilizing the inside. If such a container B1 is the conventional electron beam sterilization apparatus 1, in the shoulder part s and the trunk
  • the shoulder s and the body b approach the nozzle n due to the above inclination, so that the inner surface of the container B1 is irradiated with the electron beam e substantially evenly.
  • the operation by the operation control unit is not the rotation of the container B around the mouth m in the container B as shown in FIG. Therefore, the operation control unit in this case is not the operation control unit 4 described above, but an elevating unit 6 that elevates and lowers the body to be lifted.
  • the said inclination and exit / exit may be simultaneous or separate, as long as the electron beam e is irradiated substantially uniformly with respect to the inner surface of the container B1.
  • the electron beam sterilization apparatus 1 is suitable for sterilizing the inside of a container B2 in which the body b is greatly expanded outward. If such a container B2 is the conventional electron beam sterilization apparatus 1, in the trunk
  • the operation control unit in this case is the above-described operation control unit 4 and elevating unit 6.
  • the tilt, rotation, and withdrawal may be simultaneous or separate as long as the electron beam e is irradiated substantially uniformly on the inner surface of the container B2.
  • the inner surface of the container having a large capacity is irradiated with the electron beam e substantially evenly. So it can be sterilized properly.
  • the apparatus configuration can be simplified.
  • mouth part m in the container B it demonstrated as raising the container B, However, It is not limited to this, The nozzle n is lowered
  • the said embodiment demonstrated that there existed an insertion process after an inclination process, there may exist an inclination process after an insertion process.
  • rotation of the container B by the operation control part 4 was not demonstrated in detail, it is the meaning including all rotations, such as intermittent rotation other than continuous rotation.
  • the rotation speed is constant.
  • the rotation speed can be changed according to the distance between the nozzle n and the body b. Preferred from the viewpoint of appropriate sterilization.
  • the posture control unit 6 has been described as having the air cylinder 53, but an electric actuator or the like may be used instead of the air cylinder 53.
  • the said electron beam sterilizer 1 is provided with two or more, and the inner surface of several container B is sterilized simultaneously or sequentially. You may comprise as follows.
  • the pneumatic device group 26 that supplies compressed air has been described.
  • the present invention is not limited to this, and any hydraulic device group that supplies compressed fluid may be used.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

L'invention concerne un dispositif de stérilisation à faisceau d'électrons (1) comportant une unité de maintien de récipient (2) pour maintenir un récipient (B) et une unité d'émission de faisceau d'électrons (3) pour émettre un faisceau d'électrons dans l'intérieur du récipient (B) maintenu par l'unité de maintien de récipient (2). Ce dispositif de stérilisation à faisceau d'électrons (1) comporte une unité de commande de fonctionnement (4) pour commander le fonctionnement du récipient (B) maintenu par l'unité de maintien de récipient (2) et une unité de commande de posture (5) pour commander la posture du récipient (B) maintenu par l'unité de maintien de récipient (2). L'unité de commande de fonctionnement (4) et l'unité de commande de posture (5) commandent respectivement le fonctionnement et la posture du récipient (B) de sorte que le faisceau d'électrons est émis de façon sensiblement uniforme sur la surface intérieure du récipient (B).
PCT/JP2014/071695 2013-11-28 2014-08-20 Dispositif de stérilisation à faisceau d'électrons WO2015079750A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013245526A JP6076238B2 (ja) 2013-11-28 2013-11-28 電子線滅菌装置
JP2013-245526 2013-11-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112585062A (zh) * 2018-08-24 2021-03-30 三菱瓦斯化学株式会社 多层容器和其制造方法

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Publication number Priority date Publication date Assignee Title
DE102016123144A1 (de) * 2016-11-30 2018-05-30 Sig Technology Ag Verfahren und Füllmaschine zum Füllen von einseitig offenen Packungen mit einer von der Transportrichtung abweichenden Bearbeitungsbewegung
JP6857528B2 (ja) * 2017-03-30 2021-04-14 日立造船株式会社 電子線滅菌方法
EP4019249A4 (fr) * 2019-08-22 2022-10-05 Mitsubishi Gas Chemical Company, Inc. Corps stratifié en résine

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JP2001225814A (ja) * 2000-02-15 2001-08-21 Toyo Seikan Kaisha Ltd プリフォーム殺菌方法及びプリフォーム殺菌装置
JP2008296955A (ja) * 2007-05-31 2008-12-11 Shibuya Kogyo Co Ltd 電子線殺菌装置
JP2010058843A (ja) * 2008-08-30 2010-03-18 Krones Ag 容器の電子線滅菌

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WO2007095205A2 (fr) * 2006-02-14 2007-08-23 Advanced Electron Beams, Inc. Emetteur de faisceau electronique

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Publication number Priority date Publication date Assignee Title
JP2001225814A (ja) * 2000-02-15 2001-08-21 Toyo Seikan Kaisha Ltd プリフォーム殺菌方法及びプリフォーム殺菌装置
JP2008296955A (ja) * 2007-05-31 2008-12-11 Shibuya Kogyo Co Ltd 電子線殺菌装置
JP2010058843A (ja) * 2008-08-30 2010-03-18 Krones Ag 容器の電子線滅菌

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112585062A (zh) * 2018-08-24 2021-03-30 三菱瓦斯化学株式会社 多层容器和其制造方法

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JP2015101403A (ja) 2015-06-04

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