WO2014183861A1 - Substrat sers - Google Patents
Substrat sers Download PDFInfo
- Publication number
- WO2014183861A1 WO2014183861A1 PCT/EP2014/001276 EP2014001276W WO2014183861A1 WO 2014183861 A1 WO2014183861 A1 WO 2014183861A1 EP 2014001276 W EP2014001276 W EP 2014001276W WO 2014183861 A1 WO2014183861 A1 WO 2014183861A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sers
- substrate
- carrier
- sers substrate
- substrate according
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title claims abstract description 112
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 claims abstract description 80
- 239000000463 material Substances 0.000 claims abstract description 73
- 230000005284 excitation Effects 0.000 claims description 35
- 239000012876 carrier material Substances 0.000 claims description 30
- 230000005855 radiation Effects 0.000 claims description 27
- 238000005259 measurement Methods 0.000 claims description 21
- 229910052737 gold Inorganic materials 0.000 claims description 13
- 239000010931 gold Substances 0.000 claims description 13
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 229910052709 silver Inorganic materials 0.000 claims description 6
- 239000004332 silver Substances 0.000 claims description 6
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 4
- 239000004793 Polystyrene Substances 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 239000002086 nanomaterial Substances 0.000 claims description 3
- 239000004417 polycarbonate Substances 0.000 claims description 3
- 229920000515 polycarbonate Polymers 0.000 claims description 3
- 229920002223 polystyrene Polymers 0.000 claims description 3
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 2
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- 229910052793 cadmium Inorganic materials 0.000 claims description 2
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 239000010432 diamond Substances 0.000 claims description 2
- 229910003460 diamond Inorganic materials 0.000 claims description 2
- 239000005308 flint glass Substances 0.000 claims description 2
- 229910052733 gallium Inorganic materials 0.000 claims description 2
- 229910052738 indium Inorganic materials 0.000 claims description 2
- APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 claims description 2
- 239000005355 lead glass Substances 0.000 claims description 2
- 229910052697 platinum Inorganic materials 0.000 claims description 2
- 229910052594 sapphire Inorganic materials 0.000 claims description 2
- 239000010980 sapphire Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- 239000011701 zinc Substances 0.000 claims description 2
- 238000006073 displacement reaction Methods 0.000 claims 1
- 238000001069 Raman spectroscopy Methods 0.000 description 26
- 239000010410 layer Substances 0.000 description 16
- RMVRSNDYEFQCLF-UHFFFAOYSA-N thiophenol Chemical compound SC1=CC=CC=C1 RMVRSNDYEFQCLF-UHFFFAOYSA-N 0.000 description 12
- 230000003321 amplification Effects 0.000 description 11
- 238000003199 nucleic acid amplification method Methods 0.000 description 11
- 239000012491 analyte Substances 0.000 description 10
- 238000004364 calculation method Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 7
- 238000001514 detection method Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000005670 electromagnetic radiation Effects 0.000 description 4
- 230000014509 gene expression Effects 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 4
- 108010014173 Factor X Proteins 0.000 description 3
- 238000001237 Raman spectrum Methods 0.000 description 3
- 239000013590 bulk material Substances 0.000 description 3
- 239000004020 conductor Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002105 nanoparticle Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 238000013016 damping Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 229910000510 noble metal Inorganic materials 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910005191 Ga 2 O 3 Inorganic materials 0.000 description 1
- 229910010413 TiO 2 Inorganic materials 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 238000004374 forensic analysis Methods 0.000 description 1
- 239000005350 fused silica glass Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 150000002343 gold Chemical class 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002061 nanopillar Substances 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- BPUBBGLMJRNUCC-UHFFFAOYSA-N oxygen(2-);tantalum(5+) Chemical compound [O-2].[O-2].[O-2].[O-2].[O-2].[Ta+5].[Ta+5] BPUBBGLMJRNUCC-UHFFFAOYSA-N 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000010970 precious metal Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 239000002210 silicon-based material Substances 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- PBCFLUZVCVVTBY-UHFFFAOYSA-N tantalum pentoxide Inorganic materials O=[Ta](=O)O[Ta](=O)=O PBCFLUZVCVVTBY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
Landscapes
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
L'invention concerne un substrat SERS comprenant un support qui est composé d'un matériau de support et présente une surface, et un substrat qui est composé d'un matériau de substrat ayant une fonction diélectrique ε M, est disposé sur la surface du support et présente une structure, le matériau de support et le matériau de substrat étant choisis de manière qu'une valeur X soit au moins de 6, X étant un produit de deux facteurs qui contiennent les fonctions diélectriques du matériau de substrat ou matériau de support utilisé.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102013008104.1 | 2013-05-14 | ||
DE102013008104.1A DE102013008104A1 (de) | 2013-05-14 | 2013-05-14 | SERS-Substrat |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014183861A1 true WO2014183861A1 (fr) | 2014-11-20 |
Family
ID=50733008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2014/001276 WO2014183861A1 (fr) | 2013-05-14 | 2014-05-12 | Substrat sers |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE102013008104A1 (fr) |
WO (1) | WO2014183861A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109752359A (zh) * | 2017-11-01 | 2019-05-14 | 南京理工大学 | 聚碳酸酯/银复合表面增强拉曼基底及制备方法 |
CN109856116B (zh) * | 2019-02-28 | 2021-06-29 | 吉林大学 | 一种利用表面增强拉曼散射原位监测化学反应的分级纳米锥阵列及其制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080285024A1 (en) * | 2007-05-18 | 2008-11-20 | Prokes Sharka M | Highly efficient surface enhanced Raman and fluorescence nanostructure substrates |
US20100240144A1 (en) * | 2006-03-27 | 2010-09-23 | E2V Biosensors Limited | Improved serrs substrate |
US20110128536A1 (en) * | 2009-12-02 | 2011-06-02 | Bond Tiziana C | Nanoscale array structures suitable for surface enhanced raman scattering and methods related thereto |
US20110194106A1 (en) * | 2010-02-10 | 2011-08-11 | Makoto Murakami | method and apparatus to prepare a substrate for molecular detection |
WO2012128762A1 (fr) * | 2011-03-23 | 2012-09-27 | Hewlett-Packard Development Company, L.P. | Nanostructures hybrides pour analyse moléculaire |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19636355A1 (de) * | 1996-09-02 | 1998-03-05 | Hans Dr Amann | Verfahren und Vorrichtung zum Erhöhen der Intensität von Raman-gestreutem Licht bei der oberflächenverstärkten Raman-Spektroskopie |
ATE324587T1 (de) * | 1999-07-16 | 2006-05-15 | Univ Wm Marsh Rice | Verfahren zum nachweis von bioanalyten mittels metallische nanohüllen |
US7225082B1 (en) * | 1999-10-01 | 2007-05-29 | Oxonica, Inc. | Colloidal rod particles as nanobar codes |
US7075642B2 (en) * | 2003-02-24 | 2006-07-11 | Intel Corporation | Method, structure, and apparatus for Raman spectroscopy |
US7283228B2 (en) * | 2003-04-11 | 2007-10-16 | Purdue Research Foundation | Process and apparatus for segregation and testing by spectral analysis of solid deposits derived from liquid mixtures |
US7355704B2 (en) | 2005-06-13 | 2008-04-08 | Solaris Nanosciences, Inc. | Chemical and biological sensing using metallic particles in amplifying and absorbing media |
US7426025B2 (en) * | 2005-09-23 | 2008-09-16 | Hewlett-Packard Development Company, L.P. | Nanostructures, systems, and methods including nanolasers for enhanced Raman spectroscopy |
DE102007019166A1 (de) * | 2007-04-20 | 2008-10-30 | Fachhochschule Kiel | Verfahren zur Herstellung von Substraten für die Oberflächen-verstärkte Raman-Spektroskopie |
DE102008048342B4 (de) | 2008-09-22 | 2013-01-24 | Laser-Laboratorium Göttingen eV | SERS-Substrat, Verfahren zu seiner Herstellung und Verfahren zum Detektieren eines Analyten mittels SERS |
US8384892B2 (en) | 2008-10-03 | 2013-02-26 | Board Of Trustees Of The University Of Illinois | Surface enhanced raman spectroscopy on optical resonator (e.g., photonic crystal) surfaces |
US8427639B2 (en) * | 2009-05-07 | 2013-04-23 | Nant Holdings Ip, Llc | Surfaced enhanced Raman spectroscopy substrates |
CN102834709A (zh) * | 2010-04-20 | 2012-12-19 | 惠普发展公司,有限责任合伙企业 | 用于分子分析的多柱结构 |
EP2561322B1 (fr) * | 2010-04-20 | 2021-08-04 | Hewlett-Packard Development Company, L.P. | Dispositif d'augmentation de luminescence auto-ajustable pour luminescence exaltée de surface |
US9182338B2 (en) * | 2010-05-21 | 2015-11-10 | The Trustees Of Princeton University | Structures for enhancement of local electric field, light absorption, light radiation, material detection and methods for making and using of the same |
US9001324B2 (en) | 2010-07-30 | 2015-04-07 | Hewlett-Packard Development Company, L.P. | Optical fiber surface enhanced raman spectroscopy (SERS) probe |
GB2502242A (en) * | 2011-03-25 | 2013-11-20 | Imra America Inc | Surface-enhanced raman scattering apparatus and methods |
US20130107250A1 (en) * | 2011-10-27 | 2013-05-02 | Wei Wu | Free-standing structures for molecular analysis |
-
2013
- 2013-05-14 DE DE102013008104.1A patent/DE102013008104A1/de not_active Ceased
-
2014
- 2014-05-12 WO PCT/EP2014/001276 patent/WO2014183861A1/fr active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100240144A1 (en) * | 2006-03-27 | 2010-09-23 | E2V Biosensors Limited | Improved serrs substrate |
US20080285024A1 (en) * | 2007-05-18 | 2008-11-20 | Prokes Sharka M | Highly efficient surface enhanced Raman and fluorescence nanostructure substrates |
US20110128536A1 (en) * | 2009-12-02 | 2011-06-02 | Bond Tiziana C | Nanoscale array structures suitable for surface enhanced raman scattering and methods related thereto |
US20110194106A1 (en) * | 2010-02-10 | 2011-08-11 | Makoto Murakami | method and apparatus to prepare a substrate for molecular detection |
WO2012128762A1 (fr) * | 2011-03-23 | 2012-09-27 | Hewlett-Packard Development Company, L.P. | Nanostructures hybrides pour analyse moléculaire |
Non-Patent Citations (3)
Title |
---|
BELLO J M ET AL: "TITANIUM DIOXIDE BASED SUBSTRATE FOR OPTICAL MONITORS IN SURFACE-ENHANCED RAMAN SCATTERING ANALYSIS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 61, no. 15, 1 August 1989 (1989-08-01), pages 1779 - 1783, XP000081148, ISSN: 0003-2700, DOI: 10.1021/AC00190A600 * |
MICHEL LANGLET ET AL: "Elaboration of an Ag DEG /TiOplatform for DNA detection by surface enhanced Raman spectroscopy", SURFACE SCIENCE, NORTH-HOLLAND, vol. 605, no. 23, 16 August 2011 (2011-08-16), pages 2067 - 2072, XP028304373, ISSN: 0039-6028, [retrieved on 20110824], DOI: 10.1016/J.SUSC.2011.08.007 * |
SHUYI LI ET AL: "<title>An approach to self-cleaning SERS sensors by arraying Au nanorods on TiO<formula><inf><roman>2</roman></inf></formula> layer</title>", PROCEEDINGS OF SPIE, vol. 6647, 13 September 2007 (2007-09-13), pages 66470J - 66470J-8, XP055055446, ISSN: 0277-786X, DOI: 10.1117/12.731991 * |
Also Published As
Publication number | Publication date |
---|---|
DE102013008104A1 (de) | 2014-11-20 |
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