WO2013072213A3 - Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules - Google Patents

Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules Download PDF

Info

Publication number
WO2013072213A3
WO2013072213A3 PCT/EP2012/071855 EP2012071855W WO2013072213A3 WO 2013072213 A3 WO2013072213 A3 WO 2013072213A3 EP 2012071855 W EP2012071855 W EP 2012071855W WO 2013072213 A3 WO2013072213 A3 WO 2013072213A3
Authority
WO
WIPO (PCT)
Prior art keywords
shell
nanoparticles
silica
core
test device
Prior art date
Application number
PCT/EP2012/071855
Other languages
English (en)
Other versions
WO2013072213A2 (fr
Inventor
Cyrille GAUTIER
Lynda Si-Ahmed
Original Assignee
Metalor Technologies International Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metalor Technologies International Sa filed Critical Metalor Technologies International Sa
Priority to EP12783974.4A priority Critical patent/EP2780710A2/fr
Priority to JP2014541602A priority patent/JP2015507078A/ja
Priority to CN201280056008.9A priority patent/CN103988081A/zh
Priority to KR1020147015643A priority patent/KR20140092390A/ko
Priority to US14/358,154 priority patent/US20140308756A1/en
Publication of WO2013072213A2 publication Critical patent/WO2013072213A2/fr
Publication of WO2013072213A3 publication Critical patent/WO2013072213A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F9/00—Making metallic powder or suspensions thereof
    • B22F9/16—Making metallic powder or suspensions thereof using chemical processes
    • B22F9/18—Making metallic powder or suspensions thereof using chemical processes with reduction of metal compounds
    • B22F9/24—Making metallic powder or suspensions thereof using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/05—Metallic powder characterised by the size or surface area of the particles
    • B22F1/054—Nanosized particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/05—Metallic powder characterised by the size or surface area of the particles
    • B22F1/054—Nanosized particles
    • B22F1/0547—Nanofibres or nanotubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/05—Metallic powder characterised by the size or surface area of the particles
    • B22F1/054—Nanosized particles
    • B22F1/056—Submicron particles having a size above 100 nm up to 300 nm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/10—Metallic powder containing lubricating or binding agents; Metallic powder containing organic material
    • B22F1/102—Metallic powder coated with organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/16—Metallic particles coated with a non-metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F1/00—Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
    • B22F1/17—Metallic particles coated with metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/60—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape characterised by shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F2998/00—Supplementary information concerning processes or compositions relating to powder metallurgy

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Manufacturing & Machinery (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Powder Metallurgy (AREA)
  • Silicon Compounds (AREA)

Abstract

La présente invention concerne une nanoparticule cœur-coquille comprenant au moins un cœur composé d'au moins un premier matériau métallique à base d'au moins un métal présentant une résonance plasmonique dans le domaine choisi parmi le domaine de l'ultraviolet, le domaine du visible et le domaine du proche infrarouge, et une coquille de silice, ladite silice comprenant des groupes fonctionnels. Selon l'invention, la silice comprend à sa surface, liés de façon covalente, des agents de stabilisation de ladite nanoparticule. La présente invention concerne également une nanoparticule cœur-coquille comprenant un cœur composé d'au moins ledit premier matériau et une coquille métallique réalisée dans un second matériau à base d'au moins un métal présentant une résonance plasmonique dans le domaine choisi parmi le domaine de l'ultraviolet, le domaine du visible et le domaine du proche infrarouge, ledit second matériau étant différent du premier matériau, la coquille métallique étant stabilisée par un agent surfactant sans halogénure.La présente invention concerne également un dispositif de test par immunochromatographie pour la détection d'au moins un analyte, comprenant des agents de liaison spécifiques de l'analyte, lesdits agents de liaison étant marqués par des nanoparticules, dans lequel les nanoparticules comprennent au moins un cœur composé d'au moins ledit premier matériau et une coquille de silice, ladite silice comprenant des groupes fonctionnels.
PCT/EP2012/071855 2011-11-15 2012-11-05 Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules WO2013072213A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP12783974.4A EP2780710A2 (fr) 2011-11-15 2012-11-05 Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules
JP2014541602A JP2015507078A (ja) 2011-11-15 2012-11-05 金属／シリカコア／シェルナノ粒子、および作製方法、ならびに該粒子を含む免疫クロマトグラフィー検査デバイス
CN201280056008.9A CN103988081A (zh) 2011-11-15 2012-11-05 金属/二氧化硅芯/壳纳米颗粒、制造工艺以及包括该纳米颗粒的免疫层析测试装置
KR1020147015643A KR20140092390A (ko) 2011-11-15 2012-11-05 금속/실리카 코어/쉘 나노입자들, 제조방법 및 이러한 나노입자들을 포함하는 면역크로마토그래피 테스트 장치
US14/358,154 US20140308756A1 (en) 2011-11-15 2012-11-05 Metal/silica core/shell nanoparticles, manufacturing process and immunochromatographic test device comprising such nanoparticles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH01825/11A CH705758B1 (fr) 2011-11-15 2011-11-15 Nanoparticules cœur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules.
CH01825/11 2011-11-15

Publications (2)

Publication Number Publication Date
WO2013072213A2 WO2013072213A2 (fr) 2013-05-23
WO2013072213A3 true WO2013072213A3 (fr) 2013-08-01

Family

ID=47148789

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/071855 WO2013072213A2 (fr) 2011-11-15 2012-11-05 Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules

Country Status (7)

Country Link
US (1) US20140308756A1 (fr)
EP (1) EP2780710A2 (fr)
JP (1) JP2015507078A (fr)
KR (1) KR20140092390A (fr)
CN (1) CN103988081A (fr)
CH (1) CH705758B1 (fr)
WO (1) WO2013072213A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106198967A (zh) * 2015-04-29 2016-12-07 中国科学院宁波材料技术与工程研究所 海鲜产品检测试剂盒、其制备方法及应用

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014118775A1 (fr) * 2013-01-29 2014-08-07 Bio-Rad Haifa Ltd Dosages de détection employant des nanoparticules magnétiques
US10794904B2 (en) 2013-03-15 2020-10-06 Nicoya Lifesciences Inc. Self-referencing sensor for chemical detection
EP2905034B1 (fr) * 2014-02-06 2024-05-01 Maillefer Instruments Holding S.À.R.L. Solution d'irrigation à nanoparticules pour utilisation dans une méthode de traitement endodontique.
WO2015171892A1 (fr) * 2014-05-07 2015-11-12 Yadong Yin Nanostructures entièrement alliées à base d'argent/or
CN104551008B (zh) * 2015-01-16 2016-08-17 吉林大学 一种光谱可调的金纳米壳的制备方法
ES2856874T3 (es) * 2015-05-13 2021-09-28 Slsbio Co Ltd Método de análisis simultáneo para múltiples dianas usando múltiples nanoetiquetas metálicas
CN117434261A (zh) 2015-08-04 2024-01-23 硕腾服务有限责任公司 基于溶液的等离子体特异性结合配偶体测定中的信号放大
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US11867699B2 (en) 2016-06-10 2024-01-09 The University Of Queensland Detecting an analyte
FR3057470B1 (fr) * 2016-10-13 2021-01-29 Univ Paris Diderot Synthese de nanoparticules cœur-coquille et applications de ces nanoparticules pour la spectroscopie raman exaltee de surface
CN106324260B (zh) * 2016-11-10 2018-06-22 中国科学院成都生物研究所 一种牛血清白蛋白检测探针及其制备方法和应用
CN110892250A (zh) 2017-01-30 2020-03-17 爱贝斯股份有限公司 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
JP6923778B2 (ja) * 2017-02-10 2021-08-25 国立大学法人山梨大学 シリカコーティングされた高分散性金ナノロッドの合成方法及び合成された金ナノロッドの分散液
CN108746603A (zh) * 2018-05-31 2018-11-06 西安邮电大学 一种单分散Au-Ag合金@SiO2复合纳米颗粒的制备方法
CN109752536B (zh) * 2018-12-04 2022-03-15 浙江工业大学 基于金纳米颗粒高效组装结构的光学探针及其制备与应用
US20230001477A1 (en) * 2019-11-22 2023-01-05 Ludwig-Maximilians-Universität München Method of making nanoparticles in an aqueous solution providing functionalization and hindered aggregation in one step
CN111068722A (zh) * 2019-12-28 2020-04-28 合肥学院 一种溴化银/二氧化硅复合粉体及其制备方法
US20230159821A1 (en) * 2020-04-30 2023-05-25 Istanbul Sabahattin Zaim Üniversitesi Fabrication of the si quantum dots by uv method and thereof
CN112103393B (zh) * 2020-09-18 2023-10-10 隆基绿能科技股份有限公司 等离子激元结构及钙钛矿光电器件
KR102660010B1 (ko) * 2022-03-17 2024-04-25 울산대학교 산학협력단 메조포러스 실리카 쉘 코팅된 단일 금 나노로드를 포함하는 다기능성 배향 탐침
CN114951636B (zh) * 2022-07-11 2023-09-29 中国石油大学(华东) 银纳米立方@枝杈状纳米金核壳结构及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100150828A1 (en) * 2008-12-17 2010-06-17 National Health Research Institutes Radioactive gold nanoparticles and methods of making and using them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020004246A1 (en) 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
CN1698582A (zh) * 2005-04-29 2005-11-23 同济大学 表面包硅的近红外荧光磁性纳米粒子及其制备方法和应用
EP2122356A2 (fr) 2006-09-06 2009-11-25 QuantRX Biomedical Corporation Bandelette réactive pour chromatographie avec marqueur mobile
CN102216202A (zh) * 2008-10-03 2011-10-12 生命科技公司 磺酸酯改性纳米晶体
CN101789295B (zh) * 2009-12-22 2012-07-04 湖南大学 金壳磁性纳米颗粒及其制备和应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100150828A1 (en) * 2008-12-17 2010-06-17 National Health Research Institutes Radioactive gold nanoparticles and methods of making and using them

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GAUTIER C ET AL: "Pigments based on silica-coated gold nanorods: Synthesis, colouring strength, functionalisation, extrusion, thermal stability and colour evolution", GOLD BULLETIN WORLD GOLD COUNCIL UK, vol. 43, no. 2, June 2010 (2010-06-01), pages 94 - 104, XP002691771, ISSN: 0017-1557 *
WANG C ET AL: "SYNTHESIS ASSEMBLY, AND BIOFUNCTIONALIZATION OF SILICA-COATED GOLD NANORODS FOR COLORIMETRIC BIOSENSING", ADVANCED FUNCTIONAL MATERIALS, WILEY - V C H VERLAG GMBH & CO. KGAA, DE, vol. 16, no. 13, 5 September 2006 (2006-09-05), pages 1673 - 1678, XP001244989, ISSN: 1616-301X, DOI: 10.1002/ADFM.200500898 *
XIA CHEN ET AL: "Core-shell nanostructures for ultrasensitive detection of [alpha]-thrombin", NANOSCALE ROYAL SOCIETY OF CHEMISTRY UK, vol. 2, no. 12, November 2010 (2010-11-01), pages 2841 - 2846, XP002672708, ISSN: 2040-3364 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106198967A (zh) * 2015-04-29 2016-12-07 中国科学院宁波材料技术与工程研究所 海鲜产品检测试剂盒、其制备方法及应用

Also Published As

Publication number Publication date
CN103988081A (zh) 2014-08-13
KR20140092390A (ko) 2014-07-23
EP2780710A2 (fr) 2014-09-24
WO2013072213A2 (fr) 2013-05-23
CH705758B1 (fr) 2016-03-31
CH705758A1 (fr) 2013-05-15
US20140308756A1 (en) 2014-10-16
JP2015507078A (ja) 2015-03-05

Similar Documents

Publication Publication Date Title
WO2013072213A3 (fr) Nanoparticules coeur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules
WO2014197097A3 (fr) Capteurs de type réseau de nanocavités plasmoniques permettant d'améliorer la détection d'analytes et procédé de fabrication et d'utilisation desdits capteurs
WO2009135181A3 (fr) Procédé et compositions pour préparer des anticorps et des dérivés d'anticorps avec une fucosylation centrale réduite
CL2015000723A1 (es) Sistema y método para proveer solución de controversias para transacciones de pago electrónico
WO2009140039A3 (fr) Anticorps synthétiques
JP2010517017A5 (fr)
WO2010010329A3 (fr) Procédé de production de nanoparticules compatibles avec l'eau
MX2012004973A (es) Coordinacion de movimiento de vehiculo en un campo.
SE0801909L (sv) Sätt att framställa föremål innehållande nanometall eller kompositmetall
WO2010048585A3 (fr) Composés oligomères et méthodes
WO2007124361A3 (fr) B7-h1 soluble
EP2342162A4 (fr) Compositions et procédés pour fonctionnaliser ou réticuler des ligands sur des surfaces de nanoparticule
BRPI0915727A2 (pt) processo para a preparação de compostos nanoparticulados de cobre modificados na superfície, compostos nanoparticulados de cobre modificados na superfície, uso de compostos nanoparticulados de cobre modificados na superfície, processo para a preparação de uma dispersão aquosa, dispersóes aquosas, e, uso de dispersões aquosas.
WO2013055589A3 (fr) Refaçonnage de feuilles de verre minces
IN2014MU00285A (fr)
WO2013055142A3 (fr) Procédé de fabrication d'un conjugué multifonctionnel de biomatériau au moyen de deux types de particule et conjugué multifonctionnel de biomatériau obtenu grâce à ce procédé
WO2013175185A3 (fr) Procédé de fabrication d'un appareil de surface
WO2014026867A3 (fr) Élément optique plan, élément de détection et procédé de production correspondant
WO2010111299A3 (fr) Anticorps de synthèse
WO2011143574A3 (fr) Marqueurs biologiques plasmatiques pour le diagnostic de la maladie d'alzheimer
WO2009103907A3 (fr) Procede de gravure localisee de la surface d'un substrat
WO2010094043A3 (fr) Nanoparticules lipidiques exprimant le gadolinium destinées à l'imagerie par résonance magnétique
WO2012072987A3 (fr) Ensemble dosage et procédé
EP2495641A3 (fr) Dispositif tactile et son procédé de fabrication
WO2013017961A3 (fr) Procédé et dispositif pour modifier les propriétés des molécules ou des matériaux

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12783974

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2014541602

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 14358154

Country of ref document: US

REEP Request for entry into the european phase

Ref document number: 2012783974

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2012783974

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 20147015643

Country of ref document: KR

Kind code of ref document: A