WO2012150839A3 - Procédé pour microencapsuler de la phosphatidylsérine - Google Patents

Procédé pour microencapsuler de la phosphatidylsérine Download PDF

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Publication number
WO2012150839A3
WO2012150839A3 PCT/KR2012/003504 KR2012003504W WO2012150839A3 WO 2012150839 A3 WO2012150839 A3 WO 2012150839A3 KR 2012003504 W KR2012003504 W KR 2012003504W WO 2012150839 A3 WO2012150839 A3 WO 2012150839A3
Authority
WO
WIPO (PCT)
Prior art keywords
phosphatidylserine
microencapsulating
liquid
mixing
starch solution
Prior art date
Application number
PCT/KR2012/003504
Other languages
English (en)
Korean (ko)
Other versions
WO2012150839A2 (fr
Inventor
한지영
한정준
이관형
정국훈
황성기
Original Assignee
주식회사 두산
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 두산 filed Critical 주식회사 두산
Priority to CN201280033216.7A priority Critical patent/CN103635181A/zh
Publication of WO2012150839A2 publication Critical patent/WO2012150839A2/fr
Publication of WO2012150839A3 publication Critical patent/WO2012150839A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

La présente invention concerne un procédé pour microencapsuler de la phosphatidylsérine, qui comprend les étapes consistant : (a) à produire une composition de phosphatidylsérine liquide par fusion de phosphatidylsérine dans de l'huile et de la graisse comestibles ; (b) à préparer une solution aqueuse d'amidon, avant, après ou en même temps que l'étape (a) par mélange avec de l'amidon modifié par de l'eau, qui a été modifié pour être lipophile et hydrophile ; (c) à émulsifier par mélange et homogénéisation de la solution aqueuse d'amidon avec la composition de phosphatidylsérine liquide ; et (d) à sécher le liquide émulsifié obtenu.
PCT/KR2012/003504 2011-05-04 2012-05-04 Procédé pour microencapsuler de la phosphatidylsérine WO2012150839A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201280033216.7A CN103635181A (zh) 2011-05-04 2012-05-04 磷脂酰丝氨酸的微胶囊化方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110042580A KR101763947B1 (ko) 2011-05-04 2011-05-04 포스파티딜세린의 마이크로캡슐화 방법
KR10-2011-0042580 2011-05-04

Publications (2)

Publication Number Publication Date
WO2012150839A2 WO2012150839A2 (fr) 2012-11-08
WO2012150839A3 true WO2012150839A3 (fr) 2013-01-03

Family

ID=47108156

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/003504 WO2012150839A2 (fr) 2011-05-04 2012-05-04 Procédé pour microencapsuler de la phosphatidylsérine

Country Status (3)

Country Link
KR (1) KR101763947B1 (fr)
CN (1) CN103635181A (fr)
WO (1) WO2012150839A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103892281B (zh) * 2014-04-11 2016-04-06 内蒙古伊利实业集团股份有限公司 含磷脂酰丝氨酸的营养组合物及其制备方法与应用
CN109222109A (zh) * 2017-12-15 2019-01-18 理星（天津）生物科技有限公司 一种磷脂酰丝氨酸微丸及其制备方法和应用
CN108142950A (zh) * 2017-12-27 2018-06-12 浙江健智元生物科技有限公司 一种改善脑部神经的元宝枫籽油复合纳米微囊粉及其制备方法
CN109568292A (zh) * 2018-12-29 2019-04-05 中山百灵生物技术有限公司 一种含gpc的微凝胶及其制备方法
CN110368362B (zh) * 2019-08-01 2022-10-04 聊城大学 一种磷脂酰丝氨酸乳剂的制备方法
CN110583801A (zh) * 2019-10-17 2019-12-20 东北农业大学 一种辛烯基琥珀酸酐改性淀粉与黄原胶复合制备粉末油脂的方法
CN110692893A (zh) * 2019-11-12 2020-01-17 南通厚元生物科技有限公司 一种含有磷脂酰丝氨酸和ω-3脂肪酸的固体饮料制备方法
CN111363767A (zh) * 2020-04-22 2020-07-03 山东惠仕莱生物科技有限公司 一种食品用磷脂酰丝氨酸的制备方法
CN111418846A (zh) * 2020-04-27 2020-07-17 南通厚元生物科技有限公司 含工业大麻蛋白和磷脂酰丝氨酸的微胶囊粉末及其制备方法
CN116570018B (zh) * 2023-04-19 2024-01-02 广东萃怪香料有限公司 一种香料缓释纳米粒子及其制备方法和应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991011178A1 (fr) * 1990-01-26 1991-08-08 Fluntera Ag Encapsulation de substances actives au moyen d'amidon
KR20020091492A (ko) * 2001-05-30 2002-12-06 문장조 다공성 전분을 내부 매트릭스로한 마이크로캡슐 및 그의제조방법
KR20030058839A (ko) * 2002-01-02 2003-07-07 주식회사 두산 포스파티딜세린 함유 액상 조성물 및 그 제조방법
KR20030070798A (ko) * 2002-02-26 2003-09-02 주식회사 국순당 다당류 및 단백질 물질로 미세캡슐화된 지용성 항산화제및 그의 제조 방법
KR20080014379A (ko) * 2006-08-11 2008-02-14 주식회사 두산 포스파티딜세린 함유 고체 지질 나노입자 조성물 및 그의제조방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991011178A1 (fr) * 1990-01-26 1991-08-08 Fluntera Ag Encapsulation de substances actives au moyen d'amidon
KR20020091492A (ko) * 2001-05-30 2002-12-06 문장조 다공성 전분을 내부 매트릭스로한 마이크로캡슐 및 그의제조방법
KR20030058839A (ko) * 2002-01-02 2003-07-07 주식회사 두산 포스파티딜세린 함유 액상 조성물 및 그 제조방법
KR20030070798A (ko) * 2002-02-26 2003-09-02 주식회사 국순당 다당류 및 단백질 물질로 미세캡슐화된 지용성 항산화제및 그의 제조 방법
KR20080014379A (ko) * 2006-08-11 2008-02-14 주식회사 두산 포스파티딜세린 함유 고체 지질 나노입자 조성물 및 그의제조방법

Also Published As

Publication number Publication date
KR20120124745A (ko) 2012-11-14
CN103635181A (zh) 2014-03-12
WO2012150839A2 (fr) 2012-11-08
KR101763947B1 (ko) 2017-08-01

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