WO2012084217A1 - Kindersichere hochinerte beutelverpackung für einzeldosierte wirkstoffhaltige filme - Google Patents
Kindersichere hochinerte beutelverpackung für einzeldosierte wirkstoffhaltige filme Download PDFInfo
- Publication number
- WO2012084217A1 WO2012084217A1 PCT/EP2011/006460 EP2011006460W WO2012084217A1 WO 2012084217 A1 WO2012084217 A1 WO 2012084217A1 EP 2011006460 W EP2011006460 W EP 2011006460W WO 2012084217 A1 WO2012084217 A1 WO 2012084217A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- packaging
- weakening
- local
- packaging according
- crack
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
- B65D75/5827—Tear-lines provided in a wall portion
- B65D75/5833—Tear-lines provided in a wall portion for tearing out a portion of the wall
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2221/00—Small packaging specially adapted for product samples, single-use packages or échantillons
Definitions
- the invention relates to a child-resistant combininerte
- Film-shaped dosage forms make a special
- Packaging is comparatively long and a relatively high material usage is required.
- Touching part of the film structure must be peelable. These are usually always polyethylene-based peel layers or similar compositions that have a relatively weak seal seam strength to achieve peelability.
- WO 2010/091813 A1 describes a pouch packaging for film-shaped dosage forms, which achieves a tearability of the pouch by means of a weakening line.
- the combination of kinking and tearing at the weakening line allows one side of the package to be opened per line of weakness and thus access to the product from that side of the weave
- Preferred embodiments have the additional advantage of having a minimum film consumption per dose, are inert to drug migration, and seal seams which do not have to fulfill maximum seal strength.
- a package according to claim 1 wherein a single dose is housed in a pouch produced by sealing, which has at least on each side an outer cover layer, in particular with a minimum tensile strength of 30 N, the at least one side, preferably both sides with local weakenings that are not the edge of the packaging
- the local weakenings encompass an angle range of at least 90 ° from the point of view of the single dose
- the local weakenings are in large part, but at least completely outside the beginning and end areas, in an unsealed area, which also includes the single dose.
- At the edge of the packaging is preferably completely enclosed by a continuous sealing seam.
- the arc which the local weakenings describe can have different bending radii, but preferably has no corners or bending radii smaller than 1 mm, particularly preferably no bending radii smaller than 1 cm. In this way, an opening of the package is through
- Tearing open to the local weakenings favorably influenced by a single movement.
- the local local weakenings favorably influenced by a single movement.
- Weakenings designed so that they total or at least apart from their beginning and end areas not more than 5 cm, preferably at most 2 cm, more preferably at most 1 cm, run away from the outer contour of the single dose.
- the local weakenings run at least partially so that a portion of the single dose is exposed along the weakenings after the packaging has been torn open.
- both sides contain local weakenings to the outer layer, with the areas of weakening preferably on both sides
- the line of weakness has a shape which allows twice a crack deflection through an angle of at least 45 degrees, more preferably at least 75 degrees, thereby allowing the product to be exposed in the bag package on three sides.
- the weakening is not formed by a cut that covers the whole
- Cover layer or both cover layers severed, but by a selective weakening of the cover layer.
- crack initiation is enabled only after the bag has been bent over at a defined line.
- the outer cover layer is preferably printable.
- the cover layer wears arrows which mark the local weakenings and indicate the tear direction.
- a metal layer located between the outer cover layer and the single dose on at least one side of the bag, but preferably on both sides, a metal layer, in particular a high density
- Metal layer preferably aluminum, which the
- Bag surfaces are inert to drug migration
- Gas exchange and water vapor are.
- an inner, in particular product-contacting, sealing layer which is able to form solid and gas-tight sealing seams, which the outer cover layer
- the outer cover layer, the sealing layer and optionally the metal layer are firmly joined together, in particular in the form of a laminate.
- the sealing layer is present only in the region of the sealing seams, so that the
- Cover layer or optionally the metal layer comes into direct contact with the single dose.
- This embodiment has the further advantage of having seal seams that are inert to drug migration.
- Rissinitiation done by a second weakening in the form of a cut, which is within the bag and can be brought by bending along a crease line across the cut also to the perimeter of the bag.
- This second weakening particularly preferably has the form of a "sidecut.” Of course, this sidecut does not reach the edge of the packaging.
- weakening of the two facing layers is preferably applied by lasering or other suitable ablative process in a mold which allows the tear initiated by the incision to be forced onto the intended web.
- this second weakening there are crackers, in particular Y-shaped pieces, for trapping the crack.
- the beginning and / or end portions of the local weakenings are shaped to serve as a scavenger.
- weakening by a Y-geometry around the second weakening is achieved by lasing. Because of this Y-piece of the weakening line is the capture of the crack after crack in the second weakening possible and the targeted introduction to a defined crack path. It fulfills the function of a cracker.
- Another preferred embodiment has one leg of the Y on one side of the cover layer (e.g., the top) and the other leg on the opposite side (e.g., bottom), the superposition of both top and bottom sides completing the Y.
- This variant allows a particularly short cycle time in the production.
- the packaging and in particular the local weakenings are designed symmetrically.
- the bag packaging of right and left-handers can be easily opened and provides a second opening option, should the first attempt of the opening fail.
- Another preferred embodiment includes a
- Curve radius and material of the top layer allows to guide the crack course after initiation so that several sides of the product are exposed in a single movement.
- a particularly preferred embodiment as set forth in the drawings, characterized in that the line of weakness in the form of a U three sides of the product After the initiation of the crack by the sidecut and the subsequent capture and steering of the crack on the intended curved path through the Y-pieces of the
- the line of weakness be congruent on both sides of the bag, with the top and bottom panels of the bag being of the same material.
- the weakening line is only one-sided
- a facilitation of the function is to be achieved inter alia by suitable material selection, e.g. in that the non-weakened side is made of a material that is less tear-resistant than the locally weakened top.
- a preferred method for weakening the cover layer is laser ablation.
- the outer plastic layer can be locally burned off with high precision without injuring any metal layer that may be present. This preserves the barrier effect of a metal foil.
- Figure 1 shows a sketchy preferred packaging.
- FIGS. 2A and 2B illustrate various crack deflections.
- FIG. 3 shows a sketch of the opening of a preferred packaging.
- Figure 4 shows a sketch of a cover layer, which is provided with characters to represent the opening.
- Figure 5 shows top and bottom of a preferred
- Embodiment An example of a package according to the invention for a single dose (1) is shown in FIG. she is
- high barrier films are constructed in particular on the basis of aluminum foils with thicknesses of preferably 9-20 microns, which ensure a high degree of impermeability and inertness.
- the two aluminum foils are glued or welded together in the region of the sealing seams (3), this being achieved by a laminated heat-sealable plastic layer as the sealing layer, which consists of conventional materials known to the person skilled in the art, preferably from the group PVC, PVDC , PP, Barex (British Petroleum), PE, Aclar (Honeywell), Topaz Advanced Polymers (COP) and Surlyn are and preferably have a thickness of 20-100 microns.
- This sealing layer is usually with the
- Bag structure automatically to the product-contacting layer. The more inert the material, the more advantageous it is for product stability.
- the packaging film is formed by the outer cover layer, which has a sufficiently high tear strength, so that a manual tearing in places where there are no local weakening zones, without aids is not possible.
- a preferred material for this is PET with a thickness of 10 - 100 microns, preferably 10 - 50 microns.
- a particularly preferred packaging material has the structure (from the inside to the outside): Barex with a thickness of 20-40
- Topcoat PET with a thickness of 10-100 microns, preferably 10-50 microns.
- the outer cover layer is optionally printable to mark the product.
- the single dose (1) in an unsealed area (2). Where this unsealed area is located, the cover layer, or have both cover layers, weakening lines (4), which surround the single dose (4) partially in the form of an arc.
- FIG. 2A shows 2 possible crack deflections.
- the crack deflection in FIG. 2A is 85 ° and in FIG. 2B 90 °.
- An example of an embodiment according to FIG. 2B is one
- Packaging consisting of a bag whose top is made of a composite of PET 10-100 microns, preferably 10-50 microns, aluminum 12 microns and Barex 28-50
- the curve line of the weakening should be designed by suitable choice of radii so that the deflection of the crack by 90 ° takes place reliably.
- bag dimensions of For example, 45-65 mm while a radius of curvature of 20 aaa has been found suitable. It may be advantageous that the crack deflection does not have to reach 90 °, but somewhat less, for example 85 ° as shown in Figure 2A. This can be achieved by making the curved line trapezoidal.
- Cutting tools would not open such a bag package manually, the seal can not be opened, and the film itself can not be torn due to the stability of the outer cover layer and not.
- the cover layer As shown in Figure 4, the cover layer
- the local weakenings may have different shapes on the top (7) and bottom (8) of the package, as shown in FIG.
- the weakenings (4) are designed so that the Y-shaped areas at the beginning and end of the weakening, which serve to catch the tear, only at a superposition of the two
- Packaging halves result. This saves time during production.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Packages (AREA)
- Bag Frames (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Wrappers (AREA)
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2822544A CA2822544C (en) | 2010-12-23 | 2011-12-21 | Childproof highly-inert bag packaging for individually dosed films containing an active ingredient |
EP11819089.1A EP2655212A1 (de) | 2010-12-23 | 2011-12-21 | Kindersichere hochinerte beutelverpackung für einzeldosierte wirkstoffhaltige filme |
MX2013007290A MX341099B (es) | 2010-12-23 | 2011-12-21 | Empaque de bolsa altamente inerte a prueba de niños para peliculas con dosis individuales que contienen un ingrediente activo. |
BR112013015750A BR112013015750A2 (pt) | 2010-12-23 | 2011-12-21 | embalagem de saco altamente inerte com segurança para crianças para filmes contendo dose única de princípio ativo. |
KR1020137019362A KR101886463B1 (ko) | 2010-12-23 | 2011-12-21 | 활성 성분을 함유하는 개별 투여 필름을 위한 아동안전 고불활성 백 포장재 |
RU2013134156A RU2608068C2 (ru) | 2010-12-23 | 2011-12-21 | Безопасная для детей высокоинертная упаковка в виде мешка для единичных доз пленок, содержащих действующие вещества |
JP2013545107A JP6121336B2 (ja) | 2010-12-23 | 2011-12-21 | 有効成分を含有する個々に投薬されるフィルム用のチャイルドプルーフ高不活性バッグパッケージング |
AU2011348433A AU2011348433B2 (en) | 2010-12-23 | 2011-12-21 | Childproof highly-inert bag packaging for individually dosed films containing an active ingredient |
US13/923,660 US9370463B2 (en) | 2010-12-23 | 2013-06-21 | Childproof highly-inert packaging for individually dosed films containing an active ingredient |
US15/146,161 US9637293B2 (en) | 2010-12-23 | 2016-05-04 | Childproof highly-inert packaging for individually dosed films containing an active ingredient |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061460023P | 2010-12-23 | 2010-12-23 | |
US61/460,023 | 2010-12-23 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/923,660 Continuation-In-Part US9370463B2 (en) | 2010-12-23 | 2013-06-21 | Childproof highly-inert packaging for individually dosed films containing an active ingredient |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2012084217A1 true WO2012084217A1 (de) | 2012-06-28 |
Family
ID=45688393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2011/006460 WO2012084217A1 (de) | 2010-12-23 | 2011-12-21 | Kindersichere hochinerte beutelverpackung für einzeldosierte wirkstoffhaltige filme |
Country Status (12)
Country | Link |
---|---|
US (2) | US9370463B2 (de) |
EP (1) | EP2655212A1 (de) |
JP (1) | JP6121336B2 (de) |
KR (1) | KR101886463B1 (de) |
AR (1) | AR084451A1 (de) |
AU (1) | AU2011348433B2 (de) |
BR (1) | BR112013015750A2 (de) |
CA (1) | CA2822544C (de) |
MX (1) | MX341099B (de) |
RU (1) | RU2608068C2 (de) |
TW (1) | TWI534052B (de) |
WO (1) | WO2012084217A1 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102014104692A1 (de) * | 2014-04-02 | 2015-10-08 | Huhtamaki Flexible Packaging Germany, Zweigniederlassung Der Huhtamaki Flexible Packaging Germany Gmbh & Co. Kg | Verpackung |
US20150321438A1 (en) * | 2009-02-10 | 2015-11-12 | Lts Lohmann Therapie-Systeme Ag | Childproof, highly inert individual packaging |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10065769B2 (en) * | 2011-08-04 | 2018-09-04 | Phc Holdings Corporation | Easy-open packaging pouch and method for opening same |
CN108337918B (zh) | 2015-07-02 | 2021-07-09 | 亮锐控股有限公司 | 波长转换发光设备 |
CN115571485A (zh) * | 2017-06-16 | 2023-01-06 | 凸版印刷株式会社 | 包装袋 |
USD896634S1 (en) | 2019-01-29 | 2020-09-22 | Golden State Foods Corp. | Container |
USD896633S1 (en) | 2019-01-29 | 2020-09-22 | Golden State Foods Corp. | Container |
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-
2011
- 2011-12-21 BR BR112013015750A patent/BR112013015750A2/pt not_active Application Discontinuation
- 2011-12-21 RU RU2013134156A patent/RU2608068C2/ru active
- 2011-12-21 WO PCT/EP2011/006460 patent/WO2012084217A1/de active Application Filing
- 2011-12-21 MX MX2013007290A patent/MX341099B/es active IP Right Grant
- 2011-12-21 TW TW100147739A patent/TWI534052B/zh active
- 2011-12-21 AU AU2011348433A patent/AU2011348433B2/en not_active Ceased
- 2011-12-21 CA CA2822544A patent/CA2822544C/en active Active
- 2011-12-21 EP EP11819089.1A patent/EP2655212A1/de not_active Withdrawn
- 2011-12-21 KR KR1020137019362A patent/KR101886463B1/ko active IP Right Grant
- 2011-12-21 JP JP2013545107A patent/JP6121336B2/ja active Active
- 2011-12-21 AR ARP110104838A patent/AR084451A1/es active IP Right Grant
-
2013
- 2013-06-21 US US13/923,660 patent/US9370463B2/en active Active
-
2016
- 2016-05-04 US US15/146,161 patent/US9637293B2/en active Active
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US5878888A (en) * | 1996-10-10 | 1999-03-09 | Mcneil-Ppc, Inc. | Push through and peel child resistant blister package |
WO2000024647A1 (en) * | 1998-10-22 | 2000-05-04 | Novartis Ag | Child resistant package and method of dispensing medication |
WO2007142411A1 (en) * | 2006-06-02 | 2007-12-13 | Hee Dong Yoo | Vinyl for packing food |
WO2008019385A1 (en) * | 2006-08-08 | 2008-02-14 | Kellogg Company | Flexible container for pourable product |
WO2010025899A1 (de) | 2008-09-08 | 2010-03-11 | Lts Lohmann Therapie-Systeme Ag | Kindersichere einzeldosisverpackung für transdermale therapeutische systeme oder folienförmige darreichungsformen |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150321438A1 (en) * | 2009-02-10 | 2015-11-12 | Lts Lohmann Therapie-Systeme Ag | Childproof, highly inert individual packaging |
DE102014104692A1 (de) * | 2014-04-02 | 2015-10-08 | Huhtamaki Flexible Packaging Germany, Zweigniederlassung Der Huhtamaki Flexible Packaging Germany Gmbh & Co. Kg | Verpackung |
Also Published As
Publication number | Publication date |
---|---|
JP6121336B2 (ja) | 2017-04-26 |
KR101886463B1 (ko) | 2018-08-07 |
TW201238861A (en) | 2012-10-01 |
AR084451A1 (es) | 2013-05-15 |
CA2822544C (en) | 2019-07-30 |
US9637293B2 (en) | 2017-05-02 |
KR20130140829A (ko) | 2013-12-24 |
RU2608068C2 (ru) | 2017-01-12 |
US20160175194A9 (en) | 2016-06-23 |
MX341099B (es) | 2016-08-08 |
AU2011348433A1 (en) | 2013-07-11 |
MX2013007290A (es) | 2014-02-03 |
AU2011348433B2 (en) | 2016-09-22 |
US20160297592A1 (en) | 2016-10-13 |
US9370463B2 (en) | 2016-06-21 |
BR112013015750A2 (pt) | 2018-05-15 |
RU2013134156A (ru) | 2015-01-27 |
EP2655212A1 (de) | 2013-10-30 |
JP2014501585A (ja) | 2014-01-23 |
CA2822544A1 (en) | 2012-06-28 |
US20130301960A1 (en) | 2013-11-14 |
TWI534052B (zh) | 2016-05-21 |
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