WO2012050359A3 - 리피드로 코팅된 하이드로겔 입자 및 이의 제조방법 - Google Patents

리피드로 코팅된 하이드로겔 입자 및 이의 제조방법 Download PDF

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Publication number
WO2012050359A3
WO2012050359A3 PCT/KR2011/007578 KR2011007578W WO2012050359A3 WO 2012050359 A3 WO2012050359 A3 WO 2012050359A3 KR 2011007578 W KR2011007578 W KR 2011007578W WO 2012050359 A3 WO2012050359 A3 WO 2012050359A3
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WO
WIPO (PCT)
Prior art keywords
present
lipid
manufacturing same
manufacturing
hydrogel particles
Prior art date
Application number
PCT/KR2011/007578
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English (en)
French (fr)
Other versions
WO2012050359A2 (ko
Inventor
안은정
김도훈
임형준
심종원
김진웅
김한곤
정춘복
권이경
김준오
Original Assignee
(주)아모레퍼시픽
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020100100227A external-priority patent/KR101550941B1/ko
Priority claimed from KR1020110060318A external-priority patent/KR101839826B1/ko
Application filed by (주)아모레퍼시픽 filed Critical (주)아모레퍼시픽
Priority to US13/878,735 priority Critical patent/US9849089B2/en
Priority to CN201180049515.5A priority patent/CN103167868B/zh
Publication of WO2012050359A2 publication Critical patent/WO2012050359A2/ko
Publication of WO2012050359A3 publication Critical patent/WO2012050359A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/622—Coated by organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/65—Characterized by the composition of the particulate/core
    • A61K2800/654—The particulate/core comprising macromolecular material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)

Abstract

본 발명은 하이드로겔 입자를 리피드가 용해된 유기용매에 분산시켜 제조하는 리피드로 코팅된 하이드로겔 입자 및 그의 제조방법에 관한 것이다. 본 발명은 기존 하이드로겔 코어 베지클의 제조방법과는 다르게 하이드로겔 표면의 화학적 처리나 희석과정 없이 유화 방법을 이용해 효과적으로 제조할 수 있어 대량생산이 용이하고 약물의 봉입효율 저하를 극복할 수 있다. 이 방법을 통해 다양한 유/수용성 활성 물질의 전달체나 세포구조 모사연구에 폭넓게 활용될 수 있고, 특히 본 발명의 천연보습인자를 담지한 각질세포 모사체는 다량의 결합수를 장시간 함유하여 우수한 수분보유능과 보습효과를 나타내고, 이를 보습 성분으로 하는 보습용 화장료 조성물을 제공한다.
PCT/KR2011/007578 2010-10-14 2011-10-12 리피드로 코팅된 하이드로겔 입자 및 이의 제조방법 WO2012050359A2 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US13/878,735 US9849089B2 (en) 2010-10-14 2011-10-12 Hydrogel particle coated with lipid and method for manufacturing same
CN201180049515.5A CN103167868B (zh) 2010-10-14 2011-10-12 包覆有脂质的水凝胶粒子及其制备方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2010-0100227 2010-10-14
KR1020100100227A KR101550941B1 (ko) 2010-10-14 2010-10-14 리피드가 코팅된 하이드로겔 입자 및 이의 제조방법
KR1020110060318A KR101839826B1 (ko) 2011-06-21 2011-06-21 천연보습인자를 담지한 각질세포 모사체, 이의 제조방법, 및 이를 함유하는 보습용 화장료 조성물
KR10-2011-0060318 2011-06-21

Publications (2)

Publication Number Publication Date
WO2012050359A2 WO2012050359A2 (ko) 2012-04-19
WO2012050359A3 true WO2012050359A3 (ko) 2012-07-05

Family

ID=45938798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/007578 WO2012050359A2 (ko) 2010-10-14 2011-10-12 리피드로 코팅된 하이드로겔 입자 및 이의 제조방법

Country Status (3)

Country Link
US (1) US9849089B2 (ko)
CN (1) CN103167868B (ko)
WO (1) WO2012050359A2 (ko)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140335166A1 (en) * 2013-05-08 2014-11-13 Michael W. Fountain Methods of Making and Using Nano Scale Particles
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
JP6416772B2 (ja) 2012-12-07 2018-10-31 オックスフォード ユニヴァーシティ イノヴェーション リミテッド ３ｄプリンティングによる小滴集合
CN104274337B (zh) * 2013-07-02 2016-12-28 济南大学 一种生物液晶作为护肤品保湿成分及其制备方法
CN104910393B (zh) * 2015-06-10 2017-10-20 华南理工大学 一种纤维素硫酸酯水凝胶及其制备方法
CN105708790B (zh) * 2016-03-17 2019-12-10 金陵科技学院 一种高分子囊泡水凝胶药物载体的制备及应用
KR101852092B1 (ko) 2016-05-25 2018-04-26 엠제이바이오 주식회사 대두 삶은 물을 포함하는 하이드로겔 조성물, 이의 제조방법 및 이를 포함하는 화장료 조성물
RU2019135202A (ru) * 2017-04-05 2021-05-05 Джелесис ЭлЭлСи Улучшенные сверхвпитывающие материалы и способы их получения
CN106935933B (zh) * 2017-04-12 2019-04-05 厦门金龙联合汽车工业有限公司 一种用于增强电池模组散热的水凝胶的制备工艺
CN111225652A (zh) 2017-10-20 2020-06-02 宝洁公司 气溶胶泡沫洁肤剂
CN113015904A (zh) * 2018-11-29 2021-06-22 宝洁公司 用于筛选个人护理产品的方法
CN110496247B (zh) * 2019-09-17 2021-09-10 南通大学 一种骨再生材料的制备方法
CN115558170A (zh) * 2021-10-15 2023-01-03 北京华熙海御科技有限公司 水凝胶固体以及使用水凝胶固体评估纸巾水活度的方法
WO2023211276A1 (en) 2022-04-29 2023-11-02 Rijksuniversiteit Te Groningen Oral dosage system and methods for delivery of oxygen-sensitive therapeutic agent(s) to the lower gastrointestinal tract

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004747A1 (en) * 1995-07-27 1997-02-13 Dunn James M Drug delivery systems for macromolecular drugs
KR100186908B1 (ko) * 1996-05-23 1999-05-01 주식회사 삼양사 국소 투여형 치주염 치료제 조성물
US20020061336A1 (en) * 1999-02-03 2002-05-23 O'connor Barbara Horsey Hydrogel particle formulation
US6602952B1 (en) * 1999-06-11 2003-08-05 Shearwater Corporation Hydrogels derived from chitosan and poly(ethylene glycol) or related polymers
KR20060028604A (ko) * 2004-09-25 2006-03-30 경북대학교 산학협력단 수용성 고분자 나노 하이드로겔의 제조방법
KR100852944B1 (ko) * 2007-02-15 2008-08-19 (주)아모레퍼시픽 화학적으로 가교된 히알루론산 하이드로겔 나노입자의제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2764508B1 (fr) * 1997-06-11 2000-10-20 Lipogel Sarl Nouveaux vecteurs liposomaux de principes actifs
US6699504B2 (en) * 2000-01-28 2004-03-02 Pelias Technologies, Inc. Slow release protein polymers
US7943067B2 (en) * 2001-08-16 2011-05-17 Polytechnic Institute Of New York University Nanogels and their production using liposomes as reactors
JP2005053866A (ja) 2003-08-06 2005-03-03 Kao Corp 化粧料
US20050058674A1 (en) * 2003-09-11 2005-03-17 Kimberly-Clark Worldwide, Inc. Moisturizing and lubricating compositions
US20050112151A1 (en) * 2003-11-20 2005-05-26 Horng Liou L. Skin adherent hydrogels
US7227271B2 (en) 2004-09-21 2007-06-05 Honeywell International Inc. Method and apparatus for controlling an engine start system
WO2009015286A2 (en) * 2007-07-24 2009-01-29 Nexbio, Inc. Technology for the preparation of microparticles
KR101527957B1 (ko) 2007-08-03 2015-06-10 가부시키가이샤 코세 액상 화장료
CA2705031A1 (en) * 2007-11-15 2009-05-22 Lipodur Pharmaceutical Inc. Gel-stabilized liposome compositions, methods for their preparation and uses thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004747A1 (en) * 1995-07-27 1997-02-13 Dunn James M Drug delivery systems for macromolecular drugs
KR100186908B1 (ko) * 1996-05-23 1999-05-01 주식회사 삼양사 국소 투여형 치주염 치료제 조성물
US20020061336A1 (en) * 1999-02-03 2002-05-23 O'connor Barbara Horsey Hydrogel particle formulation
US6602952B1 (en) * 1999-06-11 2003-08-05 Shearwater Corporation Hydrogels derived from chitosan and poly(ethylene glycol) or related polymers
KR20060028604A (ko) * 2004-09-25 2006-03-30 경북대학교 산학협력단 수용성 고분자 나노 하이드로겔의 제조방법
KR100852944B1 (ko) * 2007-02-15 2008-08-19 (주)아모레퍼시픽 화학적으로 가교된 히알루론산 하이드로겔 나노입자의제조방법

Also Published As

Publication number Publication date
US9849089B2 (en) 2017-12-26
WO2012050359A2 (ko) 2012-04-19
CN103167868B (zh) 2016-08-03
US20130202667A1 (en) 2013-08-08
CN103167868A (zh) 2013-06-19

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