WO2011157561A1 - Inhaler - Google Patents

Inhaler Download PDF

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Publication number
WO2011157561A1
WO2011157561A1 PCT/EP2011/059091 EP2011059091W WO2011157561A1 WO 2011157561 A1 WO2011157561 A1 WO 2011157561A1 EP 2011059091 W EP2011059091 W EP 2011059091W WO 2011157561 A1 WO2011157561 A1 WO 2011157561A1
Authority
WO
WIPO (PCT)
Prior art keywords
inhaler
monitoring device
fluid
container
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2011/059091
Other languages
English (en)
French (fr)
Inventor
Herbert Wachtel
Andree Jung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to US13/703,998 priority Critical patent/US10155094B2/en
Priority to PL16020261T priority patent/PL3108966T3/pl
Priority to JP2013514626A priority patent/JP6067554B2/ja
Priority to EP11723062.3A priority patent/EP2582468B1/en
Priority to EP16020261.0A priority patent/EP3108966B1/en
Priority to ES11723062.3T priority patent/ES2604482T3/es
Publication of WO2011157561A1 publication Critical patent/WO2011157561A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083—Timers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00446—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means the means being located at the bottom of the container or of an enclosure surrounding the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/108—Means for counting the number of dispensing strokes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/332—Force measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8293—Solar
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0038—Inner container disposed in an outer shell or outer casing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
    • B05B11/1091—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring being first hold in a loaded state by locking means or the like, then released
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/004—Arrangements for controlling delivery; Arrangements for controlling the spray area comprising sensors for monitoring the delivery, e.g. by displaying the sensed value or generating an alarm
    • B05B12/006—Pressure or flow rate sensors
    • B05B12/008—Pressure or flow rate sensors integrated in or attached to a discharge apparatus, e.g. a spray gun
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/02—Arrangements for controlling delivery; Arrangements for controlling the spray area for controlling time, or sequence, of delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus

Definitions

  • the monitoring device comprises a pressure sensor for measuring the air pressure in a housing of the inhaler or the monitoring device, particularly in a mouthpiece of the inhaler, for detecting inhalation.
  • a pressure sensor of very simple construction can be used instead of a flow sensor.
  • the pressure sensor can be arranged separately from the mouthpiece, in particular outside the mouthpiece, but preferably within the inhaler in another region, most preferably in the lower actuating or housing part. This preferred arrangement of the pressure sensor outside a path for supply air allows a particularly simple construction.
  • Fig. 1 is a schematic section through a proposed inhaler according to a first embodiment in the untensioned state
  • the monitoring device 24 preferably comprises an interface 39 for the transmission of data, particularly for inputting or outputting data, particularly for outputting data relating to the use of the inhaler 1 .
  • the interface 39 preferably operates optically or in the infrared range. This is particularly secure against unwanted listening-in or eavesdropping.
  • the data transmission may also be effected by any other method, for example by radio or electrical contact of the transmission device 24 or printed circuit board 25 or via another electrical connection such as a plug or the like.
  • For the issuing or transmission of data it is also possible to use generally known or special protocols or interfaces such as Bluetooth, USB, SATA or the like. Alternatively or additionally, the inductive transmission of data is also possible.
  • the monitoring device 24 After being switched on or activated or woken up, the monitoring device 24 measures the pressure (air pressure) preferably continuously or at short intervals, over and over again, by means of the pressure sensor 29.
  • the monitoring device 24 is thus designed particularly for determining a pressure pattern. If, after the tensioning of the inhaler 1 or after the monitoring device 24 has been switched on or activated, a user breaths in or inhales through the mouthpiece 13 or other delivery section of the inhaler 1 , air is sucked in through the supply air pathway 44. A reduced pressure is thereby produced in the inhaler 1 or mouthpiece 13. This reduced pressure is measured or detected or determined by the pressure sensor 29 which is fluidically or pressure-connected to the supply air pathway 44 or
  • the monitoring device 24 can also indicate to the user optically and/or acoustically, for example, how long and/or how powerfully he has to breath in and/or inhale and/or when the end of the (required) inhalation is reached.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
PCT/EP2011/059091 2010-06-18 2011-06-01 Inhaler Ceased WO2011157561A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US13/703,998 US10155094B2 (en) 2010-06-18 2011-06-01 Inhaler
PL16020261T PL3108966T3 (pl) 2010-06-18 2011-06-01 Inhalator
JP2013514626A JP6067554B2 (ja) 2010-06-18 2011-06-01 吸入器
EP11723062.3A EP2582468B1 (en) 2010-06-18 2011-06-01 Inhaler
EP16020261.0A EP3108966B1 (en) 2010-06-18 2011-06-01 Inhaler
ES11723062.3T ES2604482T3 (es) 2010-06-18 2011-06-01 Inhalador

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10006334 2010-06-18
EP10006334.6 2010-06-18

Publications (1)

Publication Number Publication Date
WO2011157561A1 true WO2011157561A1 (en) 2011-12-22

Family

ID=43382538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/059091 Ceased WO2011157561A1 (en) 2010-06-18 2011-06-01 Inhaler

Country Status (8)

Country Link
US (1) US10155094B2 (https=)
EP (2) EP2582468B1 (https=)
JP (2) JP6067554B2 (https=)
DK (1) DK3108966T3 (https=)
ES (2) ES2604482T3 (https=)
HU (1) HUE051560T2 (https=)
PL (1) PL3108966T3 (https=)
WO (1) WO2011157561A1 (https=)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
NL2010405C2 (en) * 2013-03-07 2014-09-10 Medspray Xmems Bv Aerosol generator for generating an inhalation aerosol.
US10155094B2 (en) 2010-06-18 2018-12-18 Boehringer Ingelheim International Gmbh Inhaler
IT201700086905A1 (it) * 2017-07-28 2019-01-28 Amiko S R L Accessorio per inalatore, inalatore e metodo per rilevare un procedimento di somministrazione di farmaco
EP3498326A1 (de) * 2017-12-18 2019-06-19 Boehringer Ingelheim International GmbH Teilzähler für einen zerstäuber, zerstäuber und system mit einem zerstäuber und einer dockingstation
WO2019121386A1 (de) 2017-12-18 2019-06-27 Boehringer Ingelheim International Gmbh Vorrichtung zum versetzen eines inhalators in einen auslösebereiten zustand
CN110167619A (zh) * 2016-11-18 2019-08-23 诺顿（沃特福特）有限公司 具有电子元件的药物递送装置
CN110461394A (zh) * 2016-12-06 2019-11-15 诺顿（沃特福特）有限公司 具有集成电子模块的吸入装置
EP3305105B1 (en) 2012-05-14 2021-01-13 Nicoventures Trading Limited Electronic vapour provision device
EP3357356B1 (en) 2012-05-14 2021-02-17 Nicoventures Trading Limited Electronic vapour provision device
WO2021037462A1 (en) * 2019-08-23 2021-03-04 Igncyerto S.L. Dose measuring device and method in inhalers
EP3485930B1 (en) 2017-11-20 2021-04-14 Presspart Gmbh & Co. Kg Inhalation system
EP3678720A4 (en) * 2017-09-08 2021-05-26 Hcmed Innovations Co., Ltd. ATOMIZER AND NOZZLE ARRANGEMENT FOR IT
WO2021213876A1 (de) * 2020-04-22 2021-10-28 Aesculap Ag Intelligenter ölsprayadapter
US11419995B2 (en) 2019-04-30 2022-08-23 Norton (Waterford) Limited Inhaler system
CN116871078A (zh) * 2019-01-17 2023-10-13 阿普塔尔拉多尔夫策尔有限责任公司 用于排出液体、尤其是排出药用液体的分配器以及包括这种分配器的套件
US11944425B2 (en) 2014-08-28 2024-04-02 Norton (Waterford) Limited Compliance monitoring module for an inhaler
US12036359B2 (en) 2019-04-30 2024-07-16 Norton (Waterford) Limited Inhaler system
US12434022B2 (en) 2017-04-28 2025-10-07 Invox Belgium Nv Inhalation device and method

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014004437A1 (en) 2012-06-25 2014-01-03 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
GB2507104A (en) 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
GB2507103A (en) 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
MX358899B (es) 2013-08-28 2018-09-07 Gecko Health Innovations Inc Dispositivos, sistemas y métodos para monitoreo de adherencia y dispositivos, sistemas y métodos para monitorear el uso de dispensadores de consumibles.
CN105492057B (zh) * 2013-08-30 2019-05-14 安瑞智能(新西兰)有限公司 用于药物吸入器的顺从性监视器
SE538264C2 (sv) * 2013-09-17 2016-04-19 Anders Blomberg Injektionsanordning för medicinska ändamål
GB2519101A (en) 2013-10-09 2015-04-15 Nicoventures Holdings Ltd Electronic vapour provision system
CN103566444B (zh) * 2013-11-12 2015-04-15 江苏大学 一种医用盐雾测控仪及盐雾浓度定量控制方法
DE102014204939B3 (de) * 2014-03-17 2014-12-24 Aptar Radolfzell Gmbh Spender mit einer elektronische Betätigungserkennung
ES2824227T3 (es) 2014-08-28 2021-05-11 Microdose Therapeutx Inc Inhalador de polvo seco de marea con activación de sensor de presión en miniatura
CN106999681B (zh) * 2014-08-28 2021-02-02 诺顿（沃特福特）有限公司 吸入器的依从性辅助模块
US11033694B2 (en) * 2014-09-22 2021-06-15 Koninklijke Philips N.V. Inhaler with orientation sensor
GB201420039D0 (en) 2014-11-11 2014-12-24 Teva Uk Ltd System for training a user in administering a medicament
AU2015350319A1 (en) 2014-11-20 2017-06-15 Cognita Labs, LLC Method and apparatus to measure, aid and correct the use of inhalers
US10058661B2 (en) 2014-12-04 2018-08-28 Norton (Waterford) Limited Inhalation monitoring system and method
EP3037120A1 (en) 2014-12-23 2016-06-29 PARI Pharma GmbH Aerosol delivery device and operating method for the aerosol delivery device
DE102015004073B3 (de) * 2015-03-30 2016-07-07 Meda Ab Pumpkappe für einen pharmazeutischen Behälter, Einsatz für eine Pumpkappe für einen pharmazeutischen Behälter, pharmazeutischer Behälter mit der Pumpkappe, und Computerprogrammprodukt
GB2540135B (en) 2015-07-01 2021-03-03 Nicoventures Holdings Ltd Electronic aerosol provision system
JP6818008B2 (ja) 2015-07-20 2021-01-20 パール セラピューティクス，インコーポレイテッド エアロゾル送達システムおよび関連する方法
EP3366095B1 (en) 2015-10-21 2021-04-21 Vertiv Corporation Cooling systems for small equipment rooms and methods of cooling small equipment rooms
US10434525B1 (en) * 2016-02-09 2019-10-08 Steven C. Cooper Electrostatic liquid sprayer usage tracking and certification status control system
GB2547279A (en) * 2016-02-15 2017-08-16 Univ Of Wales Trinity Saint David Inhaler device
ES2915559T3 (es) * 2016-02-17 2022-06-23 Adherium Nz Ltd Monitor de adherencia para un inhalador de medicamentos con tapa sujetada
MX2018012419A (es) * 2016-04-12 2019-03-07 Biocorp Production SA Dispositivo accesorio de inhalador de dosis medida, sistema de mejora de la observancia y metodo para mejorar la observancia de uso en inhaladores de dosis medida.
FR3050116B1 (fr) * 2016-04-15 2020-05-15 Aptar France Sas Dispositif de distribution de produit fluide synchronise avec l'inhalation
ES2929335T3 (es) 2016-05-27 2022-11-28 Proveris Scient Corporation Dispositivos para el uso de dispositivos de medicamento
US20180085540A1 (en) * 2016-09-28 2018-03-29 Qualcomm Incorporated Inhaler with one or more visual sensors
JP7014791B2 (ja) 2016-11-18 2022-02-01 ノートン （ウォーターフォード） リミテッド 吸入器
FR3068894B1 (fr) * 2017-07-11 2019-08-09 Aptar France Sas Dispositif de distribution de produit fluide.
FR3069762B1 (fr) * 2017-08-03 2021-07-09 Aptar France Sas Dispositif de distribution de produit fluide.
US11672916B2 (en) * 2017-12-28 2023-06-13 Sanofi Sensor device for attachment to an injection device
FR3077496B1 (fr) * 2018-02-06 2024-03-15 Nemera La Verpilliere Dispositif d’assistance a l’utilisation d’un dispositif de distribution a activation axiale
EP3636348B1 (de) * 2018-10-08 2023-01-04 Aptar Radolfzell GmbH Set aus einem pumpspender und einer auswerteeinheit
EP3653247B1 (en) * 2018-11-19 2021-03-31 Sensirion AG Determination of air flow rate through an inhaler
GB201821331D0 (en) * 2018-12-31 2019-02-13 3M Innovative Properties Co Inhaler detection
CA3140949A1 (en) 2019-05-17 2020-11-26 Norton (Waterford) Limited Drug delivery device with electronics
MX2022007103A (es) 2019-12-10 2022-09-02 Trudell Medical Int Contador de dosis integrado.
US20210346288A1 (en) * 2020-05-11 2021-11-11 Cai Gu Huang Pharmaceutical formulation containing active metabolites of remdesivir for inhalation
US12233201B2 (en) 2020-06-19 2025-02-25 Norton (Waterford) Limited Inhaler system
US11464923B2 (en) 2020-06-19 2022-10-11 Norton (Waterford) Limited Inhaler system
KR102495311B1 (ko) * 2020-12-29 2023-02-06 홍익대학교 산학협력단 흡입기 사용방법 교정장치
WO2022163882A1 (ko) 2021-01-28 2022-08-04 주식회사 인트인 흡입기의 사용법 안내 방법 및 사용자 단말
KR102662560B1 (ko) * 2021-01-28 2024-05-02 (주)인트인 흡입기의 사용법 안내 방법 및 사용자 단말
ES3049594T3 (en) * 2021-03-03 2025-12-17 Philip Morris Products Sa Inhalation counter
CN114496152A (zh) * 2022-02-17 2022-05-13 新拓尼克科技(成都)有限公司 一种吸入型药剂的治疗数据的智能记录系统
KR20250002687A (ko) * 2022-04-29 2025-01-07 자오커 파마슈티컬 (광저우) 컴퍼니., 리미티드 트레프로스티닐 소프트 미스트 흡입제
KR102721384B1 (ko) * 2022-06-21 2024-10-23 강승완 카트리지 기반의 약물 공급 시스템
TWI840878B (zh) * 2022-07-12 2024-05-01 國立陽明交通大學 藥物吸入器用藥技巧改善系統、其嘴套及其方法
EP4342511B1 (en) * 2022-09-23 2025-10-22 Aptar Radolfzell GmbH Inhaler set
JP7618894B2 (ja) * 2022-09-29 2025-01-21 オクテット メディカル インコーポレイテッド 静電型アプリケータ用の使い捨てカートリッジ、システム、およびその方法
US11806740B1 (en) 2022-09-29 2023-11-07 Octet Medical, Inc. Disposable cartridges for electrospraying applicators, systems, and methods thereof
CN117547694B (zh) * 2024-01-12 2024-08-23 橙心数字疗法(天津)有限公司 用于软雾剂吸入用药管理的智能化装置
GB2641893A (en) * 2024-06-14 2025-12-24 Merxin Ltd A method and apparatus for testing the functionality of a liquid delivery device
CN121197596B (zh) * 2025-11-28 2026-03-17 橙心数字疗法(天津)有限公司 用药监测装置、系统及用药监测方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
WO1996006011A2 (de) 1994-08-11 1996-02-29 Boehringer Ingelheim Kg Behälter mit verschlusskappe und verfahren zur gasblasenfreien füllung von behältern
WO1997048431A2 (en) * 1996-06-20 1997-12-24 Medic-Aid Limited Dispensing system
WO2000049988A2 (de) 1999-02-23 2000-08-31 Boehringer Ingelheim International Gmbh Kartusche für eine flüssigkeit
WO2005080001A1 (de) 2004-02-24 2005-09-01 Boehringer Ingelheim International Gmbh Zerstäuber mit einer überwachungseinrichtung zur zählung von betätigungen des zerstäubers
WO2008142015A2 (en) * 2007-05-18 2008-11-27 Bang & Olufsen Medicom A/S A dispenser and a method for operating a dispenser
WO2009047173A2 (de) 2007-10-01 2009-04-16 Boehringer Ingelheim International Gmbh Zerstäuber

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1537887A1 (en) 1999-03-06 2005-06-08 Glaxo Group Limited Medicament delivery system
US6651658B1 (en) * 2000-08-03 2003-11-25 Sequal Technologies, Inc. Portable oxygen concentration system and method of using the same
US6723077B2 (en) 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
JP4795637B2 (ja) 2001-09-28 2011-10-19 カーブ テクノロジー，インコーポレイティド 鼻ネブライザー
GB0125134D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Medicament dispenser
PT2058754E (pt) 2002-06-21 2013-07-24 Glaxo Group Ltd Indicador de accionamento para um dispositivo de distribuição
EP1720659A1 (de) * 2004-02-24 2006-11-15 Boehringer Ingelheim International Gmbh Zerstäuber
WO2007138154A1 (en) 2006-05-29 2007-12-06 Wristop Technologies Oy Apparatus and method for dosing drug and wireless remote control of a drug pump
US8616199B2 (en) 2007-03-16 2013-12-31 Canon Kabushiki Kaisha Inhaler and ejection head unit attachable to the inhaler
JP5247165B2 (ja) 2007-03-16 2013-07-24 キヤノン株式会社 吐出ヘッドユニット
US20090156952A1 (en) * 2007-12-13 2009-06-18 Hunter C Eric Apparatuses and Methods for Diagnosing and Treating Respiratory Conditions
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
AT507187B1 (de) 2008-10-23 2010-03-15 Helmut Dr Buchberger Inhalator
WO2010067240A1 (en) 2008-12-11 2010-06-17 Koninklijke Philips Electronics, N.V. System and method for monitoring a metered dose inhaler
WO2011157561A1 (en) 2010-06-18 2011-12-22 Boehringer Ingelheim International Gmbh Inhaler

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
WO1996006011A2 (de) 1994-08-11 1996-02-29 Boehringer Ingelheim Kg Behälter mit verschlusskappe und verfahren zur gasblasenfreien füllung von behältern
WO1997048431A2 (en) * 1996-06-20 1997-12-24 Medic-Aid Limited Dispensing system
WO2000049988A2 (de) 1999-02-23 2000-08-31 Boehringer Ingelheim International Gmbh Kartusche für eine flüssigkeit
WO2005080001A1 (de) 2004-02-24 2005-09-01 Boehringer Ingelheim International Gmbh Zerstäuber mit einer überwachungseinrichtung zur zählung von betätigungen des zerstäubers
WO2008142015A2 (en) * 2007-05-18 2008-11-27 Bang & Olufsen Medicom A/S A dispenser and a method for operating a dispenser
WO2009047173A2 (de) 2007-10-01 2009-04-16 Boehringer Ingelheim International Gmbh Zerstäuber

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10155094B2 (en) 2010-06-18 2018-12-18 Boehringer Ingelheim International Gmbh Inhaler
US11931507B2 (en) 2012-05-14 2024-03-19 Nicoventures Trading Limited Electronic vapor provision device
EP3357356B1 (en) 2012-05-14 2021-02-17 Nicoventures Trading Limited Electronic vapour provision device
EP3305105B1 (en) 2012-05-14 2021-01-13 Nicoventures Trading Limited Electronic vapour provision device
US10369300B2 (en) 2013-03-07 2019-08-06 Medspray Xmems B.V. Aerosol generator for generating an inhalation aerosol
NL2010405C2 (en) * 2013-03-07 2014-09-10 Medspray Xmems Bv Aerosol generator for generating an inhalation aerosol.
WO2014137215A1 (en) * 2013-03-07 2014-09-12 Medspray Xmems B.V. Aerosol generator for generating an inhalation aerosol
CN105209096A (zh) * 2013-03-07 2015-12-30 美德斯普瑞埃克斯门斯公司 用于产生吸入喷雾的喷雾发生器
US20160015912A1 (en) * 2013-03-07 2016-01-21 Medspray Xmems B.V. Aerosol generator for generating an inhalation aerosol
CN105209096B (zh) * 2013-03-07 2019-02-22 美德斯普瑞埃克斯门斯公司 用于产生吸入喷雾的喷雾发生器
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
WO2014204511A3 (en) * 2013-06-18 2015-05-14 Isonea Limited Compliance monitoring for asthma inhalers
US11944425B2 (en) 2014-08-28 2024-04-02 Norton (Waterford) Limited Compliance monitoring module for an inhaler
CN110167619B (zh) * 2016-11-18 2021-11-26 诺顿（沃特福特）有限公司 具有电子元件的药物递送装置
CN110167619A (zh) * 2016-11-18 2019-08-23 诺顿（沃特福特）有限公司 具有电子元件的药物递送装置
US11439777B2 (en) 2016-11-18 2022-09-13 Norton (Waterford) Limited Drug delivery device with electronics
US11344685B2 (en) 2016-11-18 2022-05-31 Norton (Waterford) Limited Drug delivery device with electronics
US11351317B2 (en) 2016-11-18 2022-06-07 Norton (Waterford) Limited Drug delivery device with electronics
US11357935B2 (en) 2016-11-18 2022-06-14 Norton (Waterford) Limited Drug delivery device with electronics
CN110461394A (zh) * 2016-12-06 2019-11-15 诺顿（沃特福特）有限公司 具有集成电子模块的吸入装置
US12329900B2 (en) 2016-12-06 2025-06-17 Norton (Waterford) Limited Inhalation device with integrated electronics
US11266796B2 (en) 2016-12-06 2022-03-08 Norton (Waterford) Limited Inhalation device with integrated electronics
US12434022B2 (en) 2017-04-28 2025-10-07 Invox Belgium Nv Inhalation device and method
IT201700086905A1 (it) * 2017-07-28 2019-01-28 Amiko S R L Accessorio per inalatore, inalatore e metodo per rilevare un procedimento di somministrazione di farmaco
US11701480B2 (en) 2017-07-28 2023-07-18 Amiko S.R.L Accessory for an inhaler, inhaler and method for detecting a drug administration process
EP3678720A4 (en) * 2017-09-08 2021-05-26 Hcmed Innovations Co., Ltd. ATOMIZER AND NOZZLE ARRANGEMENT FOR IT
EP3485930B1 (en) 2017-11-20 2021-04-14 Presspart Gmbh & Co. Kg Inhalation system
WO2019121386A1 (de) 2017-12-18 2019-06-27 Boehringer Ingelheim International Gmbh Vorrichtung zum versetzen eines inhalators in einen auslösebereiten zustand
US12390605B2 (en) 2017-12-18 2025-08-19 Boehringer Ingelheim International Gmbh Device for putting an inhaler into a triggering-ready state
EP3498326A1 (de) * 2017-12-18 2019-06-19 Boehringer Ingelheim International GmbH Teilzähler für einen zerstäuber, zerstäuber und system mit einem zerstäuber und einer dockingstation
CN116871078A (zh) * 2019-01-17 2023-10-13 阿普塔尔拉多尔夫策尔有限责任公司 用于排出液体、尤其是排出药用液体的分配器以及包括这种分配器的套件
US11419995B2 (en) 2019-04-30 2022-08-23 Norton (Waterford) Limited Inhaler system
US12036359B2 (en) 2019-04-30 2024-07-16 Norton (Waterford) Limited Inhaler system
US12138387B2 (en) 2019-04-30 2024-11-12 Norton (Waterford) Limited Inhaler system
WO2021037462A1 (en) * 2019-08-23 2021-03-04 Igncyerto S.L. Dose measuring device and method in inhalers
WO2021213876A1 (de) * 2020-04-22 2021-10-28 Aesculap Ag Intelligenter ölsprayadapter
US12558447B2 (en) 2020-04-22 2026-02-24 Aesculap Ag Smart oil spray adapter

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PL3108966T3 (pl) 2020-04-30
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JP6543240B2 (ja) 2019-07-10
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US20130269685A1 (en) 2013-10-17
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EP3108966A1 (en) 2016-12-28
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DK3108966T3 (da) 2020-01-02
US10155094B2 (en) 2018-12-18

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