WO2011112117A1 - Prémélange pour produits alimentaires - Google Patents
Prémélange pour produits alimentaires Download PDFInfo
- Publication number
- WO2011112117A1 WO2011112117A1 PCT/RU2010/000460 RU2010000460W WO2011112117A1 WO 2011112117 A1 WO2011112117 A1 WO 2011112117A1 RU 2010000460 W RU2010000460 W RU 2010000460W WO 2011112117 A1 WO2011112117 A1 WO 2011112117A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dihydroquercetin
- premix
- propylene glycol
- products
- solution
- Prior art date
Links
- 235000013305 food Nutrition 0.000 title claims abstract description 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 90
- CXQWRCVTCMQVQX-LSDHHAIUSA-N (+)-taxifolin Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC=C(O)C(O)=C1 CXQWRCVTCMQVQX-LSDHHAIUSA-N 0.000 claims abstract description 87
- XCGZWJIXHMSSQC-UHFFFAOYSA-N dihydroquercetin Natural products OC1=CC2OC(=C(O)C(=O)C2C(O)=C1)c1ccc(O)c(O)c1 XCGZWJIXHMSSQC-UHFFFAOYSA-N 0.000 claims abstract description 79
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 45
- 235000011187 glycerol Nutrition 0.000 claims abstract description 20
- 229920000136 polysorbate Polymers 0.000 claims abstract description 18
- 239000000945 filler Substances 0.000 claims abstract description 10
- 229930003935 flavonoid Natural products 0.000 claims description 15
- 235000017173 flavonoids Nutrition 0.000 claims description 15
- -1 flavonoid compounds Chemical class 0.000 claims description 14
- FTVWIRXFELQLPI-ZDUSSCGKSA-N (S)-naringenin Chemical compound C1=CC(O)=CC=C1[C@H]1OC2=CC(O)=CC(O)=C2C(=O)C1 FTVWIRXFELQLPI-ZDUSSCGKSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- WGEYAGZBLYNDFV-UHFFFAOYSA-N naringenin Natural products C1(=O)C2=C(O)C=C(O)C=C2OC(C1)C1=CC=C(CC1)O WGEYAGZBLYNDFV-UHFFFAOYSA-N 0.000 claims description 8
- 229940117954 naringenin Drugs 0.000 claims description 8
- 235000007625 naringenin Nutrition 0.000 claims description 8
- 239000012535 impurity Substances 0.000 claims description 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 abstract description 11
- 230000003078 antioxidant effect Effects 0.000 abstract description 10
- 235000009508 confectionery Nutrition 0.000 abstract description 7
- 235000013365 dairy product Nutrition 0.000 abstract description 5
- 230000001476 alcoholic effect Effects 0.000 abstract description 4
- 230000004872 arterial blood pressure Effects 0.000 abstract 1
- 229950008882 polysorbate Drugs 0.000 abstract 1
- 230000001012 protector Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 description 32
- 235000013772 propylene glycol Nutrition 0.000 description 26
- 239000000654 additive Substances 0.000 description 12
- 230000000694 effects Effects 0.000 description 11
- 235000006708 antioxidants Nutrition 0.000 description 10
- 238000010835 comparative analysis Methods 0.000 description 9
- 238000002360 preparation method Methods 0.000 description 8
- 230000008859 change Effects 0.000 description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- 235000013351 cheese Nutrition 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 235000019219 chocolate Nutrition 0.000 description 4
- 235000015142 cultured sour cream Nutrition 0.000 description 4
- 240000002129 Malva sylvestris Species 0.000 description 3
- 235000006770 Malva sylvestris Nutrition 0.000 description 3
- 229920001213 Polysorbate 20 Polymers 0.000 description 3
- 235000015278 beef Nutrition 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003925 fat Substances 0.000 description 3
- 235000019197 fats Nutrition 0.000 description 3
- 150000002215 flavonoids Chemical class 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 239000004310 lactic acid Substances 0.000 description 3
- 235000014655 lactic acid Nutrition 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 235000013622 meat product Nutrition 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 239000012071 phase Substances 0.000 description 3
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 3
- RTIXKCRFFJGDFG-UHFFFAOYSA-N Chrysin Natural products C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 description 2
- FGUBFGWYEYFGRK-HNNXBMFYSA-N Pinocembrin Natural products Cc1cc(C)c2C(=O)C[C@H](Oc2c1)c3ccccc3 FGUBFGWYEYFGRK-HNNXBMFYSA-N 0.000 description 2
- 235000019486 Sunflower oil Nutrition 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 235000013334 alcoholic beverage Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 235000013373 food additive Nutrition 0.000 description 2
- 239000002778 food additive Substances 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 235000019645 odor Nutrition 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 150000002978 peroxides Chemical class 0.000 description 2
- URFCJEUYXNAHFI-ZDUSSCGKSA-N pinocembrin Chemical compound C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=CC=C1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000002600 sunflower oil Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- OIQOAYVCKAHSEJ-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol;hexadecanoic acid;octadecanoic acid Chemical compound OCCOCC(OCCO)COCCO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O OIQOAYVCKAHSEJ-UHFFFAOYSA-N 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241000218652 Larix Species 0.000 description 1
- 235000005590 Larix decidua Nutrition 0.000 description 1
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000003217 anti-cancerogenic effect Effects 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 235000008452 baby food Nutrition 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 229940088623 biologically active substance Drugs 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- 235000012970 cakes Nutrition 0.000 description 1
- 230000004856 capillary permeability Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000020057 cognac Nutrition 0.000 description 1
- 235000020186 condensed milk Nutrition 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 235000014048 cultured milk product Nutrition 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- KQNGHARGJDXHKF-UHFFFAOYSA-N dihydrotamarixetin Natural products C1=C(O)C(OC)=CC=C1C1C(O)C(=O)C2=C(O)C=C(O)C=C2O1 KQNGHARGJDXHKF-UHFFFAOYSA-N 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 235000021056 liquid food Nutrition 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000002114 nanocomposite Substances 0.000 description 1
- 239000007908 nanoemulsion Substances 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 235000013324 preserved food Nutrition 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- OJTDGPLHRSZIAV-UHFFFAOYSA-N propane-1,2-diol Chemical compound CC(O)CO.CC(O)CO OJTDGPLHRSZIAV-UHFFFAOYSA-N 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- OTNVGWMVOULBFZ-UHFFFAOYSA-N sodium;hydrochloride Chemical compound [Na].Cl OTNVGWMVOULBFZ-UHFFFAOYSA-N 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 235000002316 solid fats Nutrition 0.000 description 1
- 239000002594 sorbent Substances 0.000 description 1
- 235000021262 sour milk Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 235000014268 sports nutrition Nutrition 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 235000013522 vodka Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/035—Organic compounds containing oxygen as heteroatom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the invention relates to the food industry, in particular to a premix based on dihydroquercetin, which can be used in dairy, confectionery, alcoholic, non-alcoholic products.
- Dihydroquercetin in the form of a powder with a purity of 92-96% is used as an additive to many food products, such as juices, milk, sunflower oil, dairy products, cheeses, fat-containing canned food, (see, for example, RF patents 2043030, 2097977, 2183966, 2186097, 2243725, 2254858, 2313258, 2362544, 2370047, RF application 2004113197, 2006117747, etc.).
- Dihydroquercetin is a known compound from the group of flavonoids and has a wide spectrum of action. First of all, it has a positive effect on human health. The drug inhibits the development of tumor cells, activates the regeneration of the gastric mucosa, has an antitoxic effect, improves the functioning of the heart, liver, gall bladder, gastrointestinal tract, prostate gland, kidneys, bladder, has the properties of a natural antioxidant, antioxidant and vitamin P.
- dihydroquercetin in the form of a powder is the inability to dissolve it in liquid fractions due to the physicochemical properties of this compound.
- the latter is practically insoluble in water and in liquid food products (juices, milk, sunflower oil, sour-milk products, cheeses, canned fat, etc.), therefore it is very difficult to introduce it into the final product. This makes it impossible to evenly distribute dihydroquercetin throughout the product.
- dihydroquercetin in powder with insufficiently high purity has a characteristic woody odor, which is unacceptable for use in many products.
- a hydrophobic phase is prepared in the form of a transparent homogeneous solution containing a flavonoid, for example, taxifolin (dihydroquercetin) as a biologically active substance, labrafil, tween and a surfactant, for example, propylene glycol in the amount of 5-8.3% in May, by mixing these components at a temperature of 60-70 ° C.
- a flavonoid for example, taxifolin (dihydroquercetin) as a biologically active substance, labrafil, tween and a surfactant, for example, propylene glycol in the amount of 5-8.3% in May
- a surfactant for example, propylene glycol
- the nanocomposition provides uniform sustained release of the active substance.
- the nanocomposition is multicomponent and the method for its preparation includes several stages, which is a disadvantage.
- various associated components are also used.
- the closest analogue of the present invention is the composition of the bioflavonoid complex for food and perfumery products, including dihydroquercetin, dihydroquempferol, naringenin, eriodiktiol and pinocembrin in the following ratios of components,%: dihydroquercetin - 87-95; dihydrocampferol - 3.5-9.5; naringenin - 0.5-1.3; eriodiktiol - 0.9-2.1; pinocembrin - 0.04-0.10 (RU2183966, Siblarex Limited Liability Company, 06.27.2002).
- the authors of the present invention unexpectedly found that the use of propylene glycol or glycerol or tween as a filler in a certain ratio with dihydroquercetin allows you to get a premix, which is devoid of all the disadvantages of additives and premixes based on dihydroquercetin, known from the prior art. It was also found that the premix of the present invention allows dihydroquercetin to exhibit all its unique properties more vividly. Thus, the premix of the present invention has the properties of a stronger antioxidant. Thus, the new premix can be used in two ways: as an antioxidant and a functional food ingredient.
- premix inhibits lipid peroxidation, while preserving the original organoleptic (sensory) indicators in the product for a longer time - taste, smell, color, taking into account which the consumer evaluates the quality of the purchased product.
- this premix it is possible to increase the shelf life of products by 1.5-3 times.
- the premix is added to the product in the amount necessary for the functional direction.
- a premix with a content of 10% dihydroquercetin and 90% of the filler can be used for the dairy industry (whole milk powder, condensed milk, baby food, cottage cheese, sour cream, yogurts, fermented milk products, ice cream, cream, cheeses, dry cottage cheese, drinking milk, butter). Premix increases the shelf life of dairy products and gives them a functional purpose;
- premix containing 90% dihydroquercetin and 10% filler can be used for alcoholic beverages (beer, cognac, opaque alcoholic beverages, vodka, wine). Premix gives functional properties.
- Premix with a content of 70% dihydroquercetin and 30% filler can be used for soft drinks, juices, in the confectionery industry (chocolate, sweets, cakes, cookies). Premix gives functional properties.
- Premix with a content of 50% dihydroquercetin and 50% filler can be used for sports nutrition. Gives functional properties.
- Premix containing 80% dihydroquercetin and 20% filler can be used for the oil and fat and meat industries (liquid oils, solid fats, mayonnaises, sauces). Increases shelf life and gives functional properties.
- the manifestation of the corresponding antioxidant and biologically active effects, and the creation of products based on premix, can be intended for the prevention of a number of diseases in humans, with an insufficient level of antioxidants in the body and impaired capillary permeability.
- Dihydroquercetin when ingested with food as a functional ingredient, can break the chain of peroxide degradation (LP) in the body and thereby prevent disturbances caused by the action of an adverse factor on the human body as a whole, on an organ, tissue site or on individual cells, i.e. on the occurrence and development of the pathological process.
- LP peroxide degradation
- the premix of the present invention has a number of cumulative advantages over other antioxidants: a) lack of toxicity, b) physiological harmlessness c) high activity at low concentrations, d) the absence of extraneous tastes and odors in the product when antioxidant is added, e) resistance to temperature, mechanical impacts and processes occurring in the manufacture of products.
- the antioxidant properties of the premix it is possible to use it to improve existing and or create new food products. This is due to the fact that the process of peroxide degradation is characteristic of many food lipids, which leads to a loss of nutritional properties of products and a reduction in their shelf life. It is important to keep in mind that the consumption of products with oxidized lipids can cause a number of pathological conditions of the body. In this connection, the search for methods and means of protecting lipids from initiating peroxidation is important not only to extend the shelf life of food products, but also from a pathogenetic point of view.
- the premix according to the invention contains dihydroquercetin and an excipient selected from the group comprising propylene glycol, glycerin, tween in the following ratio of components,% May: dihydroquercetin 10-90%; filler - 90-10%.
- Used dihydroquercetin may contain as impurities related flavonoid compounds in an amount up to 20% of the total amount of dihydroquercetin.
- Related flavonoid compounds may be dihydrocampferol, naringenin, or mixtures thereof.
- Dihydroquercetin is obtained according to the following technological scheme: grinding of raw materials (larch wood), extraction, filtration of the obtained extract, salting out the extract — filtering the obtained extract, purifying the extract, planting the extract on a sorbent, isolating dihydroquercetin, drying dihydroquercetin.
- Propylene glycol is a known compound and has the properties of an emulsifier, preservative, moisture retainer and stabilizer of the substances dissolved in it.
- propylene glycol is used that meets the requirements of technical specifications, sanitary norms and instructions “Hygienic requirements for the use of food additives” SanPiN 2.3.2.1290-03 ”, page 78, index 3.4.9.
- the difference between the proposed premix and the closest known premix described in RF2362544 is the qualitative and quantitative composition of the components.
- a method for preparing a premix consists in mixing dihydroquercetin with one of the carriers mentioned above.
- the optimal temperature of dihydroquercetin in the preparation of premix is 40-90 ° C, depending on the ratio of components and the desired functional use.
- the resulting premix solution has the following physical properties:
- Example 1 Preparation of Propyl Anglycol Premix Dihydroquercetin
- the viscosity of the resulting solution at 20 ° C is 45.66 centipoise and does not increase compared to the initial PG.
- the solution When the solution is heated to 100 ° C for 1 hour, the solution remains transparent, the color and viscosity of the solution do not change. When storing the solution for 30 days at 20 ° C, the transparency, color and viscosity of the solution do not change.
- Used dihydroquercetin may contain as impurities related flavonoid compounds in an amount up to 20% of the total amount of dihydroquercetin.
- Related flavonoid compounds may be dihydrocampferol, naringenin, or mixtures thereof.
- the solution When the solution is heated to 100 ° C for 1 hour, the solution remains transparent, the color and viscosity of the solution do not change. When storing the solution for 30 days at 20 ° C, the transparency, color and viscosity of the solution do not change.
- Used dihydroquercetin may contain as impurities related flavonoid compounds in an amount up to 20% of the total amount of dihydroquercetin.
- Related flavonoid compounds may be dihydrocampferol, naringenin, or mixtures thereof.
- the solution When the solution is heated to 100 ° C for 1 hour, the solution remains transparent, the color and viscosity of the solution do not change. When storing the solution for 30 days at 20 ° C, the transparency, color and viscosity of the solution do not change.
- Used dihydroquercetin may contain as impurities related flavonoid compounds in an amount up to 20% of the total amount of dihydroquercetin.
- Related flavonoid compounds may be dihydrocampferol, naringenin, or mixtures thereof.
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2010109194 | 2010-03-12 | ||
RU2010109194 | 2010-03-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2011112117A1 true WO2011112117A1 (fr) | 2011-09-15 |
Family
ID=44563711
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2010/000460 WO2011112117A1 (fr) | 2010-03-12 | 2010-08-24 | Prémélange pour produits alimentaires |
PCT/RU2010/000461 WO2011112118A1 (fr) | 2010-03-12 | 2010-08-24 | Prémélange pour la nourriture d'animaux de ferme |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2010/000461 WO2011112118A1 (fr) | 2010-03-12 | 2010-08-24 | Prémélange pour la nourriture d'animaux de ferme |
Country Status (2)
Country | Link |
---|---|
RU (1) | RU2456811C2 (fr) |
WO (2) | WO2011112117A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2498612C1 (ru) * | 2012-06-09 | 2013-11-20 | Государственное научное учреждение Северо-Кавказский научно-исследовательский институт животноводства Россельхозакадемии (ГНУ СКНИИЖ Россельхозакадемии) | Кормовая добавка для высокопродуктивных коров "биоэффект-корова" с гепатопротекторным и иммуностимулирующим действием |
RU2596069C2 (ru) * | 2013-04-15 | 2016-08-27 | Государственное научное учреждение Северо-Кавказский научно-исследовательский институт животноводства Россельхозакадемии (ГНУ СКНИИЖ Россельхозакадемии) | Корм для цыплят-бройлеров и способ его применения |
RU2606084C1 (ru) * | 2015-06-29 | 2017-01-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет инженерных технологий" (ФГБОУ ВО "ВГУИТ") | Способ приготовления кормовой добавки |
WO2020045689A1 (fr) * | 2018-08-27 | 2020-03-05 | (주) 마샬 코퍼레이션 | Complexe antioxydant et composition pour produire celui-ci |
RU2715630C1 (ru) * | 2019-04-16 | 2020-03-02 | Общество с ограниченной ответственностью "Кедровитин" | Способ приготовления кормовой смеси "тайга" на основе дигидрокверцетина |
RU2711099C1 (ru) * | 2019-04-16 | 2020-01-15 | Общество с ограниченной ответственностью "Кедровитин" | Способ приготовления кормовой смеси для сельскохозяйственных животных и птицы |
RU2729386C1 (ru) * | 2019-12-09 | 2020-08-06 | Федеральное государственное бюджетное научное учреждение "Поволжский научно-исследовательский институт производства и переработки мясомолочной продукции" (ГНУ НИИММП) | Способ продления репродуктивного периода кур родительского стада |
CN113317398A (zh) * | 2021-02-08 | 2021-08-31 | 福建傲农生物科技集团股份有限公司 | 一种仔猪预混剂及其制备方法和应用 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2088256C1 (ru) * | 1996-12-02 | 1997-08-27 | Тюкавкина Нонна Арсеньевна | Средство для комплексной терапии заболеваний "диквертин" и способ его получения |
RU2154967C1 (ru) * | 1999-01-27 | 2000-08-27 | Шачнев Юрий Дмитриевич | Биологически активная добавка "биоскан-с" и способ ее получения |
RU2183966C1 (ru) * | 2001-07-06 | 2002-06-27 | Общество с ограниченной ответственностью "Сибларекс" | Состав биофлавоноидного комплекса сибларекс для биологически активных добавок, медицинских и химико-фармацевтических изделий и способ получения биофлавоноидного комплекса сибларекс для биологически активных добавок, медицинских и химико-фармацевтических изделий |
RU2186097C1 (ru) * | 2001-07-06 | 2002-07-27 | Общество с ограниченной ответственностью "Сибларекс" | Состав биофлавоноидного комплекса сибел для пищевых и парфюмерных изделий и способ получения биофлавоноидного комплекса сибел для пищевых и парфюмерных изделий |
RU2362544C2 (ru) * | 2007-04-09 | 2009-07-27 | Закрытое акционерное общество "Санкт-Петербургский институт фармации" | Наноэмульсия с биологически активными веществами |
RU2375079C2 (ru) * | 2004-03-29 | 2009-12-10 | Уайт | Поливитаминные и минеральные пищевые добавки |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU1768118C (ru) * | 1989-08-02 | 1992-10-15 | Одесский технологический институт пищевой промышленности им.М.В.Ломоносова | Способ приготовлени комбикорма |
RU2041647C1 (ru) * | 1992-04-02 | 1995-08-20 | Николай Иванович Лебедев | Кормовая добавка для животных |
RU2192756C2 (ru) * | 2000-12-28 | 2002-11-20 | Федеральное государственное унитарное предприятие "Всероссийский научно-исследовательский институт пресноводного рыбного хозяйства" | Способ приготовления корма |
GB0202258D0 (en) * | 2002-01-31 | 2002-03-20 | Dodson & Horrell Ltd | Annimal feed supplement |
RU2328132C2 (ru) * | 2006-05-11 | 2008-07-10 | Всероссийский государственный научно-исследовательский институт животноводства (ВИЖ) | Способ выведения тяжелых металлов и радионуклидов из организма животных |
RU2348169C2 (ru) * | 2007-03-29 | 2009-03-10 | Виктор Клавдиевич Трофимов | Способ кормления сельскохозяйственных животных и птицы |
RU2366268C1 (ru) * | 2008-03-11 | 2009-09-10 | Институт химии твердого тела и механохимии Сибирского отделения Российской академии наук (ИХТТМ СО РАН) | Премикс и способ его получения |
RU2403801C1 (ru) * | 2009-10-19 | 2010-11-20 | Екатерина Васильевна Карпун | Кормовая добавка |
-
2010
- 2010-08-24 WO PCT/RU2010/000460 patent/WO2011112117A1/fr active Application Filing
- 2010-08-24 WO PCT/RU2010/000461 patent/WO2011112118A1/fr active Application Filing
- 2010-08-24 RU RU2010142403/10A patent/RU2456811C2/ru not_active IP Right Cessation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2088256C1 (ru) * | 1996-12-02 | 1997-08-27 | Тюкавкина Нонна Арсеньевна | Средство для комплексной терапии заболеваний "диквертин" и способ его получения |
RU2154967C1 (ru) * | 1999-01-27 | 2000-08-27 | Шачнев Юрий Дмитриевич | Биологически активная добавка "биоскан-с" и способ ее получения |
RU2183966C1 (ru) * | 2001-07-06 | 2002-06-27 | Общество с ограниченной ответственностью "Сибларекс" | Состав биофлавоноидного комплекса сибларекс для биологически активных добавок, медицинских и химико-фармацевтических изделий и способ получения биофлавоноидного комплекса сибларекс для биологически активных добавок, медицинских и химико-фармацевтических изделий |
RU2186097C1 (ru) * | 2001-07-06 | 2002-07-27 | Общество с ограниченной ответственностью "Сибларекс" | Состав биофлавоноидного комплекса сибел для пищевых и парфюмерных изделий и способ получения биофлавоноидного комплекса сибел для пищевых и парфюмерных изделий |
RU2375079C2 (ru) * | 2004-03-29 | 2009-12-10 | Уайт | Поливитаминные и минеральные пищевые добавки |
RU2362544C2 (ru) * | 2007-04-09 | 2009-07-27 | Закрытое акционерное общество "Санкт-Петербургский институт фармации" | Наноэмульсия с биологически активными веществами |
Also Published As
Publication number | Publication date |
---|---|
RU2456811C2 (ru) | 2012-07-27 |
WO2011112118A1 (fr) | 2011-09-15 |
RU2010142403A (ru) | 2012-04-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2011112117A1 (fr) | Prémélange pour produits alimentaires | |
US7118688B2 (en) | Antioxidant compositions and methods of use thereof | |
US20070218150A1 (en) | Active Oxygen Scavenging Agent and Moisturizing Agent Containing Wild Watermelon Extract | |
BRPI0814726B1 (pt) | processo para preparar um produto nutricional e produto nutricional | |
JP2005312430A (ja) | マカ抽出物含有アルコール飲料 | |
JP4700694B2 (ja) | 魚油を含有する食品サプリメント | |
AU2006308219B2 (en) | Food composition | |
EP3001916A1 (fr) | Aliment ou boisson comprenant une huile d' extrait d'algues | |
RU2457713C2 (ru) | Премикс для пищевых продуктов | |
AU2011254726B2 (en) | Theobromine for increasing HDL-cholesterol | |
RU2462883C2 (ru) | Пищевой эмульсионный продукт | |
JP2003334022A (ja) | 持久力向上用食品組成物 | |
JP7106829B2 (ja) | マウスコーティング感増強剤 | |
WO2009003832A2 (fr) | Composition comprenant des polyphénols | |
JP2005171116A (ja) | 香味又は香気の劣化抑制剤 | |
RU2812482C1 (ru) | Композиция для получения оксигенного продукта | |
RU2542520C2 (ru) | Безалкогольный напиток (варианты) | |
RU2423057C2 (ru) | Пищевой эмульсионный продукт | |
KR20020024175A (ko) | 약이되는 물질을 함유한 유제품의 제조방법. | |
JP2006160668A (ja) | 過酸化脂質生成抑制剤 | |
RU2694680C1 (ru) | Майонезный соус | |
KR100535706B1 (ko) | 분리대두단백질을 이용한 녹차두유 조성물 및 그 제조방법 | |
JP2007068480A (ja) | 耐熱性多価不飽和脂肪酸製剤およびそれを含有する食品 | |
RU2653886C1 (ru) | Пищевой эмульсионный продукт и способ его получения | |
JP2007006839A (ja) | ローヤルゼリー、松樹皮抽出物及び核酸を含有する冷菓 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 2010142404 Country of ref document: RU |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 10847567 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
32PN | Ep: public notification in the ep bulletin as address of the adressee cannot be established |
Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC (EPO FORM 1205A, DATED 25-01-2013) |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 10847567 Country of ref document: EP Kind code of ref document: A1 |