WO2010117150A2 - Film médical multicouche et utilisation associée - Google Patents
Film médical multicouche et utilisation associée Download PDFInfo
- Publication number
- WO2010117150A2 WO2010117150A2 PCT/KR2010/001824 KR2010001824W WO2010117150A2 WO 2010117150 A2 WO2010117150 A2 WO 2010117150A2 KR 2010001824 W KR2010001824 W KR 2010001824W WO 2010117150 A2 WO2010117150 A2 WO 2010117150A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypropylene
- multilayer film
- copolymer
- styrene
- medical
- Prior art date
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B25/00—Layered products comprising a layer of natural or synthetic rubber
- B32B25/04—Layered products comprising a layer of natural or synthetic rubber comprising rubber as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B25/08—Layered products comprising a layer of natural or synthetic rubber comprising rubber as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
- B32B27/302—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising aromatic vinyl (co)polymers, e.g. styrenic (co)polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2250/00—Layers arrangement
- B32B2250/03—3 layers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2250/00—Layers arrangement
- B32B2250/24—All layers being polymeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2270/00—Resin or rubber layer containing a blend of at least two different polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2274/00—Thermoplastic elastomer material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/30—Properties of the layers or laminate having particular thermal properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/30—Properties of the layers or laminate having particular thermal properties
- B32B2307/306—Resistant to heat
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/40—Properties of the layers or laminate having particular optical properties
- B32B2307/412—Transparent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/50—Properties of the layers or laminate having particular mechanical properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/50—Properties of the layers or laminate having particular mechanical properties
- B32B2307/558—Impact strength, toughness
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/10—Polypropylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
Definitions
- the chemical liquid packaging bag is required to have flexibility such as crushability, transparency that can easily observe the state of use of the solution, heat resistance, heat sealability, drop impact resistance, etc., and drug stability that can withstand high temperature sterilization.
- the medical sap bag of the general sap bag is formed by bonding the two layers of the film through the thermal bonding, for this purpose is produced by melting the raw material of the inner layer and sealing under conditions that heat and pressure is applied outside the outer layer.
- the blocking phenomenon due to the adhesion of the film inner layers during high temperature sterilization occurs when the Tm of the inner layer is low and the viscous behavior becomes strong at the sterilization temperature (during viscoelastic behavior of the polymer).
- the raw material having a high Tm has good affinity between the raw materials constituting the inner layer, it occurs when the surface energy at the interface is small and the inner layers adhere to each other.
- the term 'polypropylene' is made using only propylene monomers, and includes all polypropylenes having isotactic, syndiotactic, and atactic structures.
- a melt index (based on ASTM D1238) of 7 to 9 g / 10 minutes, a density of 0.85 to 0.95 and a softening point of 145 to 165 ⁇ are used.
- polyethylene which is one of the components of the inner layer 6, is a component that makes the multilayer film have antiblocking property. If the content is less than the above range, it is difficult to realize antiblocking property. It leads to degradation.
- fusing point of the outer layer 2 is 145-165 degreeC
- middle layer 4 is 140-155 degreeC
- the inner layer 6 has the range of 125-140 degreeC.
- Medical multilayer film according to the present invention is not particularly limited in the present invention, it can be produced using a method known in the art.
- the multilayer film is capable of co-extrusion and lamination of the film and the film.
- the anti-blocking property was checked after the three-side sealing of the film (100 X 120 mm), filled with 50 mL of distilled water, after sealing the remaining one side at 121 ° C. for 30 minutes under high temperature steam sterilization.
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Laminated Bodies (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
La présente invention a pour objet un film médical multicouche et son utilisation, et plus particulièrement un film médical multicouche comprenant : une couche externe comprenant un type de polymère de polypropylène choisi dans le groupe comprenant le polypropylène, un copolymère de polypropylène, et leur combinaison ; une couche intermédiaire comprenant de 50 à 70 % en poids d'un type de polymère de polypropylène choisi dans le groupe comprenant le polypropylène, un copolymère de polypropylène, et leur combinaison, et de 30 à 50 % en poids d'un élastomère thermoplastique ; et une couche interne comprenant de 95 à 99,9 % en poids d'un type de polymère de polypropylène choisi dans le groupe comprenant le polypropylène, un copolymère de polypropylène, et leur combinaison, et de 0,1 à 5 % en poids de polyéthylène. La présente invention concerne aussi l'utilisation du film. Le film multicouche présente une excellente transparence, une excellente résistance thermique, et d'excellentes propriétés de scellage, et empêche un phénomène de blocage dans lequel les couches internes des films se collent les unes sur les autres pendant une stérilisation à haute température. Par conséquent, le film multicouche de la présente invention peut être utilisé dans des réceptacles pour sève pour l'emballage et l'administration d'un liquide médical tel que la sève ou le sang, des poches médicales, des récipients pour produits de contraste et des récipients pour le sang.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020090029429A KR101091527B1 (ko) | 2009-04-06 | 2009-04-06 | 의료용 다층 필름, 및 이의 용도 |
KR10-2009-0029429 | 2009-04-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010117150A2 true WO2010117150A2 (fr) | 2010-10-14 |
WO2010117150A3 WO2010117150A3 (fr) | 2010-12-09 |
Family
ID=42936674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2010/001824 WO2010117150A2 (fr) | 2009-04-06 | 2010-03-25 | Film médical multicouche et utilisation associée |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR101091527B1 (fr) |
WO (1) | WO2010117150A2 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020020825A1 (fr) | 2018-07-23 | 2020-01-30 | Borealis Ag | Film en polypropylène multicouche |
WO2020245251A2 (fr) | 2019-06-05 | 2020-12-10 | Borealis Ag | Film en polypropylène multicouche |
CN112584815A (zh) * | 2018-08-21 | 2021-03-30 | 费森尤斯卡比德国有限公司 | 输液袋 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101144388B1 (ko) | 2010-11-09 | 2012-05-10 | 기아자동차주식회사 | 교통정보 제공 시스템 및 단말기, 이를 이용한 교통정보 제공 방법 |
KR20130005634A (ko) * | 2011-07-07 | 2013-01-16 | 바프렉스 주식회사 | 의료 수액백용 내포장재 필름 |
KR101516503B1 (ko) * | 2013-12-26 | 2015-05-04 | 강동현 | 의료용 주사제 밀봉 마개 조성물 |
KR102551304B1 (ko) * | 2017-11-30 | 2023-07-03 | 롯데케미칼 주식회사 | 투명성, 연질성 및 내충격성이 우수한 의료용 필름 |
CN111361121B (zh) * | 2017-12-22 | 2022-09-09 | 福建恒安家庭生活用品有限公司 | 基于seps弹性体的柔软底膜的制备方法 |
KR102264553B1 (ko) * | 2020-02-28 | 2021-06-15 | 주식회사 한서씨앤에프 | 보호필름용 수지조성물 및 이에 의하여 제조된 의료용 폴리올레핀계 2차 포장용 필름 |
KR102242811B1 (ko) | 2020-10-29 | 2021-04-20 | 이승영 | 기능성 의료용 다층 필름 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010096295A (ko) * | 2000-04-18 | 2001-11-07 | 유승렬 | 우수한 유연성 및 투명성을 갖는 의료용 다층 공압출 필름 |
KR100347072B1 (ko) * | 2000-06-14 | 2002-08-03 | 주식회사 케미타운 | 의료용 다층 필름 |
KR100760264B1 (ko) * | 2000-06-28 | 2007-09-19 | 후지모리 고교 가부시키가이샤 | 의료용 액체용기용 플라스틱 필름 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100619324B1 (ko) * | 2000-08-11 | 2006-09-06 | 에스케이 주식회사 | 유연성 및 투명성이 우수한 의료용 다층 공압출 필름 |
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2009
- 2009-04-06 KR KR1020090029429A patent/KR101091527B1/ko active IP Right Grant
-
2010
- 2010-03-25 WO PCT/KR2010/001824 patent/WO2010117150A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010096295A (ko) * | 2000-04-18 | 2001-11-07 | 유승렬 | 우수한 유연성 및 투명성을 갖는 의료용 다층 공압출 필름 |
KR100347072B1 (ko) * | 2000-06-14 | 2002-08-03 | 주식회사 케미타운 | 의료용 다층 필름 |
KR100760264B1 (ko) * | 2000-06-28 | 2007-09-19 | 후지모리 고교 가부시키가이샤 | 의료용 액체용기용 플라스틱 필름 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020020825A1 (fr) | 2018-07-23 | 2020-01-30 | Borealis Ag | Film en polypropylène multicouche |
US11440300B2 (en) | 2018-07-23 | 2022-09-13 | Borealis Ag | Multilayer polyproylene film |
CN112584815A (zh) * | 2018-08-21 | 2021-03-30 | 费森尤斯卡比德国有限公司 | 输液袋 |
WO2020245251A2 (fr) | 2019-06-05 | 2020-12-10 | Borealis Ag | Film en polypropylène multicouche |
US11752743B2 (en) | 2019-06-05 | 2023-09-12 | Borealis Ag | Multilayer polypropylene film |
Also Published As
Publication number | Publication date |
---|---|
WO2010117150A3 (fr) | 2010-12-09 |
KR20100111057A (ko) | 2010-10-14 |
KR101091527B1 (ko) | 2011-12-13 |
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